• Title/Summary/Keyword: GBS

Search Result 184, Processing Time 0.022 seconds

Superplastic Deformation Characteristics in Powder Metallurgy Al-Li Aluminum Alloy (분말야금 Al-Li 합금의 초소성 변형 특성)

  • 장영원
    • Proceedings of the Korean Society for Technology of Plasticity Conference
    • /
    • 1999.03b
    • /
    • pp.129-130
    • /
    • 1999
  • The superplastic deformation characteristics is powder metallurgy(PM) Al-Li alloy has been studied within the framework of a recently proposed internal variable theory of superplasticity(SSP). The flow curves were obtained by performing a series of load relaxation tests at the temperature range from 45$0^{\circ}C$ to 52$0^{\circ}C$ It has been found that the overall flow curves were separated into the grain boundary sliding(GBS) and the accommodating dislocation glide processes/ The tensile curves were also obtained to clarify the superplastic deformation bahavior of PM Al-Li alloy. The microstructural features of PM AL-Li alloy have been examined through the transmission electron microscopy.

  • PDF

Intravenous Immunoglobulin Therapy in Peripheral Neuropathy (말초신경병증에 대한 정맥내 면역글로불린 요법)

  • Kim, Nam Hee;Park, Kyung Seok
    • Annals of Clinical Neurophysiology
    • /
    • v.8 no.1
    • /
    • pp.6-15
    • /
    • 2006
  • Intravenous immunoglobulin (IVIg) is the treatment of choice for many autoimmune neuropathic disorders such as Guillain-Barre syndrome (GBS), chronic inflammatory Demyelinating neuropathy (CIDP), and multifocal motor neuropathy (MMN). IVIg is preferred because the adverse reactions are milder and fewer than the other immune-modulating methods such as steroid, other immunosuppressant such as azathioprine, and plasmapheresis. IVIg also has been used in other autoimmune neuromuscular disorders (inflammatory myopathy, myasthenia gravis, and Lambert-Eaton myasthenic syndrome) and has been known as safe and efficient agent in these disorders. Since IVIg would get more indications and be used more commonly, clinicians need to know the detailed mechanism of action, side effects, and practical points of IVIg.

  • PDF

Development of Design Technology for Safety Enhancement of Damaged Ship (손상 선박의 안전성 향상 설계 기술 개발)

  • Lee, Soon-Sup;Lee, Dong-Kon;Kim, Ki-Sup
    • Journal of the Society of Naval Architects of Korea
    • /
    • v.46 no.1
    • /
    • pp.69-77
    • /
    • 2009
  • Loss of human lives and properties including environmental damage due to large scale accidents requires change of our perception to marine safety. IMO is trying to re-establish overall marine safety system through long term plan such as GBS. Along this line, current regulation based safety evaluation is in process of changing into performance based methods, and for this transition, simulation based safety evaluation during design stage considering damage is highly necessary. In this paper, first, damage scenario is developed from IMO regulations and accident case studies. Then an integrated and simulation based safety evaluation prototype system considering both damage stability and structural safety is developed for the use during ship design process.

Drift Control for Multistory Moment Frames under Lateral Loading

  • Grigorian, Carl E.;Grigorian, Mark
    • International Journal of High-Rise Buildings
    • /
    • v.2 no.4
    • /
    • pp.355-365
    • /
    • 2013
  • The paper reports results of recent studies on the effects of column support conditions on the lateral displacements of moment frames at incipient collapse. The article presents a number of exercises in the plastic theory of structures that lead to useful design formulae. It has been shown that Drift Shifting (DS) is caused due to differences in the stiffnesses of adjoining columns, and that changes in drift ratios are more pronounced at first level column joints in both fixed as well as pinned base frames. In well proportioned moment frames, DS in the upper levels could be minimized, even reduced to zero. It has been demonstrated that DS can be eliminated in properly designed fixed and grade beam supported (GBS) moment frames. Several examples, including symbolic P-delta effects, have been provided to demonstrate the validity and the applications of the proposed ideas to the design and drift control of moment frames. The proposed methodology is exact within the bounds of the theoretical assumptions and is well suited for preliminary design and teaching purposes.

Structural Strength Assessment of Forward Cargo Hold for Kamsarmax CSR Bulk Carrier (Kamsarmax급 CSR Bulk Carrier의 Forward Cargo Hold 구조적 특성 및 안정성 검증)

  • Hwang, Sang-Wook;Park, Jeong-Jun
    • Special Issue of the Society of Naval Architects of Korea
    • /
    • 2011.09a
    • /
    • pp.17-20
    • /
    • 2011
  • The International Association of Classification Societies (IACS) had developed the Common Structural Rules (CSR) for bulk carriers as per the needs noted above. ISO and IMO GBS (Goal-Based Standards) are now being developed in this regard. This study has been prepared to verity the strength of forward cargo hold of 82,000 DWT class bulk carriers. A cargo hold/tank 3-D FE model was established to assess the structural adequacy of the primary structural members with the loading conditions. Full breadth model was established for the analysis considering asymmetric nature of structural layout and loading conditions. To summarize this result of structural assessment based on IACS CRS for bulk carrier, it is benefit to design this kind of bulk carriers and to study the strength assessment for the similar type of bulk carriers.

  • PDF

안전한 자율운항선박 운용을 위한 기능요건 및 기준 개발 기초연구

  • 박혜리;박한선
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
    • /
    • 2023.05a
    • /
    • pp.215-216
    • /
    • 2023
  • 자율운항선박은 제4차 산업혁명 시대의 핵심기술인 사물인터넷과 빅데이터, 인공지능 등이 집약된 미래 고부가가치 선박으로 주목 받고 있으며, 자율운항선박의 도입 및 상용화를 위한 국제적 제도 검토 작업이 활발히 진행되고 있다. 국제해사기구(IMO)는 2017년부터새로운 용어 정립과 함께 기존 협약 규정식별작업(RSE)을 수행했다. 그 결과 기존 협약의 개정과 함께 자율운항선박 운항을 위한 새로운 규정 개발 필요성을 인식하고, 지난해 4월 '자율운항선박 코드(MASS Code)' 개발 로드맵 개발과 함께 세부 기준 개발 작업을 본격화했다. 본 논문에서는 현재 국제해사기구(IMO)에서 개발 중인 자율운항선박 코드를 기반으로 안전한 자율운항선박 운용을 위한 기능요건을 분석하고 세부 기준 및 방향을 제시했다.

  • PDF

Bacterial Meningitis in Children in One Tertiary Hospital (소아의 세균성 수막염)

  • Oh, Ji Eun;Chang, Ji Yeon;Kwon, Young Se;Kim, Soon Ki;Son, Byong Kwan;Hong, Young Jin
    • Pediatric Infection and Vaccine
    • /
    • v.10 no.2
    • /
    • pp.208-214
    • /
    • 2003
  • Purpose : We performed a retrospective study on bacterial meningitis in children, pertaining to the causative organisms, bacterial resistance to antibiotics and the effect of recent introduction of Haemophilus influenzae type b(Hib) vaccine. Methods : We analysed the forty-three cases of bacterial meningitis which had been treated at the Inha University Hospital from June 1996 to June 2003. Results : Nineteen cases(44.2%) of them were infants younger than 2 months of age, and 29 cases(67.5%) younger than 1 year of age. The common causative organisms under 2 months of age were group B streptococcus(GBS)(47.4%), E. coli(21.1%), and Klebsiella pneumoniae(21.1%). In the age group beyond 2 months of age, S. pneumoniae were seen in 50 %, H. influenzae in 16.7% and N. meningitidis in 16.7%. All of the five cases of Hib meningitis had not been vaccinated for Hib. There has been no Hib meningitis cases since 2001. Overall fatality rate was 4.5%, and complication occurred in 39%. Complications was significantly less frequent in patients resumed to be treated within 48 hours after onset compared to after 48 hours after onset. Penicillin resistance of S. pneumoniae and GBS isolated among bacterial meningitis cases was high. Conclusion : Timing of treatment after the onset of the disease appeared the most important factor for prognosis of bacterial meningitis. The cases of H. influenzae meningitis have decreased probably due to Hib vaccination.

  • PDF

The Causative Organisms of Neonatal and Pediatric Bacterial Meningitis in Korea(2000~2005) (국내 신생아와 소아 세균성 수막염의 원인균주(2000~2005))

  • Jeon, Yun Suk;Lee, Soo Young;Mok, Hye Rin;Lee, Jung Hyun;Kim, Jong Hyun;Hur, Je Kyun;Kang, Jin Han
    • Pediatric Infection and Vaccine
    • /
    • v.13 no.2
    • /
    • pp.130-136
    • /
    • 2006
  • Purpose : The purpose of this study is to confirm the epidemiologic change of the causative organisms of neonatal and pediatric bacterial meningitis in Korea. And we tried to evaluate the risk factors correlated with prognosis which was available on the day of admission. Methods : Retrospectively, we reviewed the medical records of 57 patients admitted for bacterial meningitis at six hospitals affiliated with Catholic Medical Center for 6 years(Jan. 2000~Dec. 2005). Results : 22 cases(38.6%) of them were neonates under 28 days and 35 cases were infants and children ; 16 cases(28.1%), under 1 year ; 6 cases(10.5%), under 5 years ; 13 cases (22.8%), under 15 years. In neonates, 16 cases(72.7%) were caused by group B streptococcus (GBS). In infants and children, S. pneumoniae(25.7%), H. influenzae type b(Hib)(22.8%) and N. meningitidis(22.8%) were common cause of bacterial meningitis in order. In the informations available on the day of admission, weight deficit for age under 3 percentile, increased CRP level and decreased glucose level of CSF were related to poor prognosis(P<0.05). Conclusion : GBS became a leading cause of neonatal bacterial meningitis. Though, pneumoccocal, Hib and meningococcal meningitis were confirmed as major causes of bacterial meningitis. The routine immunization of pneumococcal and Hib vaccines will be considered, and it is necessary to introduce meningococcal vaccines to our country in the future.

  • PDF

Construction of Genetic Linkage Map and Identification of Quantitative Trait Loci in Populus davidiana using Genotyping-by-sequencing (Genotyping-by-sequencing 기법을 이용한 사시나무(Populus davidiana) 유전연관지도 작성 및 양적형질 유전자좌 탐색)

  • Suvi Kim;Yang-gil Kim;Dayoung Lee;Hye-jin Lee;Kyu-Suk Kang
    • Journal of Korean Society of Forest Science
    • /
    • v.112 no.1
    • /
    • pp.40-56
    • /
    • 2023
  • Tree species within the Populus genus grow rapidly and have an excellent capacity to absorb carbon, conferring substantial ability to effective purify the environment. Poplar breeding can be achieved rapidly and efficiently if a genetic linkage map is constructed and quantitative trait loci (QTLs) are identified. Here, a high-density genetic linkage map was constructed for the control pollinated progeny using the genotyping-by-sequencing (GBS) technique, which is a next-generation sequencing method. A search was also performed for the genes associated with quantitative traits located in the genetic linkage map by examining the variables of height and diameter at root collar, and resilience to insect damage. The height and diameter at root collar were measured directly, while the ability to recover from insect damage was scored in a 4-year-old breeding population of aspen hybrids (Odae19 × Bonghyeon4 F1) established in the research forest of Seoul National University. After DNA extraction, paternity was confirmed using five microsatellite markers, and only the individuals for which paternity was confirmed were used for the analysis. The DNA was cut using restriction enzymes and the obtained DNA fragments were prepared using a GBS library and sequenced. The analyzed results were sorted using Populus trichocarpa as a reference genome. Overall, 58,040 aligned single-nucleotide polymorphism (SNP) markers were identified, 17,755 of which were used for mapping genetic linkages. The genetic linkage map was divided into 19 linkage groups, with a total length of 2,129.54 cM. The analysis failed to identify any growth-related QTLs, but a gene assumed to be related to recovery from insect damage was identified on linkage group (chromosome) 4 through genome-wide association study.