Pediatric Infection and Vaccine
- Volume 13 Issue 2
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- Pages.130-136
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- 2006
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- 2384-1079(pISSN)
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- 2384-1087(eISSN)
The Causative Organisms of Neonatal and Pediatric Bacterial Meningitis in Korea(2000~2005)
국내 신생아와 소아 세균성 수막염의 원인균주(2000~2005)
- Jeon, Yun Suk (Department of Pediatrics, College of Medicine, The Catholic University of Korea) ;
- Lee, Soo Young (Department of Pediatrics, College of Medicine, The Catholic University of Korea) ;
- Mok, Hye Rin (Department of Pediatrics, College of Medicine, The Catholic University of Korea) ;
- Lee, Jung Hyun (Department of Pediatrics, College of Medicine, The Catholic University of Korea) ;
- Kim, Jong Hyun (Department of Pediatrics, College of Medicine, The Catholic University of Korea) ;
- Hur, Je Kyun (Department of Pediatrics, College of Medicine, The Catholic University of Korea) ;
- Kang, Jin Han (Department of Pediatrics, College of Medicine, The Catholic University of Korea)
- 전윤숙 (가톨릭대학교 의과대학 소아과학교실) ;
- 이수영 (가톨릭대학교 의과대학 소아과학교실) ;
- 목혜린 (가톨릭대학교 의과대학 소아과학교실) ;
- 이정현 (가톨릭대학교 의과대학 소아과학교실) ;
- 김종현 (가톨릭대학교 의과대학 소아과학교실) ;
- 허재균 (가톨릭대학교 의과대학 소아과학교실) ;
- 강진한 (가톨릭대학교 의과대학 소아과학교실)
- Published : 2006.11.30
Abstract
Purpose : The purpose of this study is to confirm the epidemiologic change of the causative organisms of neonatal and pediatric bacterial meningitis in Korea. And we tried to evaluate the risk factors correlated with prognosis which was available on the day of admission. Methods : Retrospectively, we reviewed the medical records of 57 patients admitted for bacterial meningitis at six hospitals affiliated with Catholic Medical Center for 6 years(Jan. 2000~Dec. 2005). Results : 22 cases(38.6%) of them were neonates under 28 days and 35 cases were infants and children ; 16 cases(28.1%), under 1 year ; 6 cases(10.5%), under 5 years ; 13 cases (22.8%), under 15 years. In neonates, 16 cases(72.7%) were caused by group B streptococcus (GBS). In infants and children, S. pneumoniae(25.7%), H. influenzae type b(Hib)(22.8%) and N. meningitidis(22.8%) were common cause of bacterial meningitis in order. In the informations available on the day of admission, weight deficit for age under 3 percentile, increased CRP level and decreased glucose level of CSF were related to poor prognosis(P<0.05). Conclusion : GBS became a leading cause of neonatal bacterial meningitis. Though, pneumoccocal, Hib and meningococcal meningitis were confirmed as major causes of bacterial meningitis. The routine immunization of pneumococcal and Hib vaccines will be considered, and it is necessary to introduce meningococcal vaccines to our country in the future.
목 적 : 최근 국내에서 신생아와 소아 세균성 수막염의 발생빈도, 원인균주의 변화, 임상양상, 치료방법, 합병증을 파악하고 예후에 관련된 위험인자를 분석하고자 하였다. 방 법 : 2000년 1월부터 2005년 12월까지 6년간 가톨릭대학교 6개 대학병원에 세균성 수막염으로 신생아실 혹은 소아과 병동에 입원한 57명을 대상으로 의무기록을 후향적으로 조사하였다. 결 과 : 전체 57명 중 신생아는 22명, 1개월 이상 15세까지 소아는 35명이었고 남녀 성비는 1.7 : 1이었다. 연평균 입원 환아수는