• Title/Summary/Keyword: GB34

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The Effect of HK-1001 Pharmacopuncture on Hyperlipidemia Induced Rats (HK-1001 약침이 흰쥐의 고지혈증에 미치는 영향)

  • Kim, Ji-Nam;Hong, Kwon-Eui
    • Journal of Pharmacopuncture
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    • v.11 no.2
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    • pp.41-53
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    • 2008
  • Objective&Methods The purpose of this study is to observe the effects of HK-1001 Pharmacopuncture at GB34(Yangleungchean) on hyperlipidemia in rats. The author performed several experimental items to analyze the levels of various components and enzymes in serum, urine and liver, as well as the histological changes of liver and aorta. Results 1. HK-1001 Pharmacopuncture infusion solution increased the cell viability rate, DPPH radical scavenging activity and HMG-CoA reductase inhibition rate in rat liver cells. 2. The levels of total cholesterol, free cholesterol, LDL-cholesterol, phospholipid in serum and AI(atherogenic index) were decreased, and the ratio of HDL to TCL(HDL/TCL) and the level of TG in serum were increased as compared with those of the control group. 3. In the HK-1001 group, serum GOT was significantly lower than those of the HG group and the saline group, and serum ALP was significantly higher than that of the HG group. 4. Hepatic GSH and catalase activities were significantly increased as compared with those of the saline group. Conclusion From the above results, it is suggested that HK-1001 Pharmacopuncture at GB34 has a therapeutic effect on hyperlipidemia.

Drug-Induced Dyskinesia Outpatient Suspected to be Induced by Risperidone Management with Yigan-san with Citri Pericarpium and Pinelliae Rhizoma (modified Yigan-san, Yokukan-san Kachimpihang), Electro-Acupuncture at GB34 (陽陵泉), and Stopping Suspected Medication: A Case Report (Risperidone으로 유발된 것으로 의심된 약물유발성 이상운동증에 대한 의심약물 중단 및 억간산가진피반하와 GB34(陽陵泉) 전침치료를 통한 외래기반 관리 : 증례보고)

  • Roh, Min-yeong;Jang, Seung-won;Kim, Hyun-ho;Han, Yang-hee;Leem, Jungtae
    • The Journal of Internal Korean Medicine
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    • v.40 no.6
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    • pp.1303-1310
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    • 2019
  • Objectives: Drug-induced Parkinsonism has similar symptoms to Parkinson's disease, but each has different causes. Drug-induced Parkinsonism accounts for the largest proportion of secondary Parkinsonism We report a outpatient case of drug-induced Parkinsonism after taking Risperidone, an atypical antipsychotic. Method: With discontinuing of antipsychotic drug, modified Yigan-san extract was administered for 12 weeks, and acupuncture and electroacupuncture procedures were performed 20 times. Results: Abnormal Involuntary Movement Scale (AIMS) score decreased from 23 to 3 during 59 days of treatment period without adverse events and worsening of depression. The Patient was highly satisfied. Conclusion: Modified Yigan-san and electroacupuncture (GB34) can be used as an treatment option in patients with drug-induced Parkinsonism.

A Review of Case Reports on the Application of Acupuncture as a Treatment for Fracture since 2013 (골절에 침 치료를 적용한 2013년 이후 증례보고 문헌고찰)

  • Paik, Seung-Won;Nam, Kyeong-Ho;Choi, Seung-Kwan;Lee, Jung-Han;Han, Yun-Hee
    • Journal of Korean Medicine Rehabilitation
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    • v.31 no.4
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    • pp.49-63
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    • 2021
  • Objectives This study aimed to investigate the trend in treating fracture with acupuncture and to evaluate the quality of case reports. Methods All case reports of fractures treated with acupuncture were extracted from four Korean web databases. We classified these studies by five fracture sites and investigated frequently used meridian and acupoint, outcome measurements, treatment period. And we assessed the quality of the case reports by the STandards for Reporting Interventions in Clinical Trials of Acupuncture (STRICTA) guidelines. Results A total of 33 case reports were included. The outcome measurements were divided into six categories, and the outcome measurements used in more than three studies showed improvement in patient symptoms. The mainly used meridians for each fracture site were as follows: chest and abdomen (GB, LR, CV), back (BL, GB), upper limb (LI, TE), lower Limb (GB, ST, BL, SP). The most commonly used acupoints for each fracture site were as follows: chest and abdomen (Ashi points, GB24, GB25, GB26, LR13, LR14, CV16, CV17, CV18, CV19), back (BL23, BL24, BL25, BL26, BL40, BL51, BL52, BL60, GB34), upper limb (LI4, LI10, LI11, TE3), lower limb (GB34, GB40). According to the STRICTA guidelines, more than 54.54% of the reports were found to be 'not reported' or 'not sufficient' in the following categories: 'response sought', 'description of participating acupuncturist', and 'number of needle insertions per subject per session'. Conclusions The meridians and acupuncture points frequently used for acupuncture treatment of fractures were near the fracture site. Future clinical studies involving acupuncture must be reported in accordance with the STRICTA guidelines to improve transparency and uniformity.

40 Gb/s Traveling-Wave Electroabsorption Modulator-Integrated DFB Lasers Fabricated Using Selective Area Growth

  • Kwon, Yong-Hwan;Choe, Joong-Seon;Sim, Jae-Sik;Kim, Sung-Bock;Yun, Ho-Gyeong;Choi, Kwang-Seong;Choi, Byung-Seok;Nam, Eun-Soo
    • ETRI Journal
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    • v.31 no.6
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    • pp.765-769
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    • 2009
  • In this paper, we present the fabrication of 40 Gb/s traveling-wave electroabsorption modulator-integrated laser (TW-EML) modules. A selective area growth method is first employed in 40 Gb/s EML fabrication to simultaneously provide active layers for lasers and modulators. The 3 dB bandwidth of a TW-EML module is measured to be 34 GHz, which is wider than that of a lumped EML module. The 40 Gb/s non-return-to-zero eye diagram shows clear openings with an average output power of +0.5 dBm.

A 10Gb/s Analog Adaptive Equalizer for Backplanes (백플레인용 10Gbps 아날로그 어댑티브 이퀄라이저)

  • Yoo, Kwi-Sung;Han, Gun-Hee;Park, Sung-Min
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.44 no.9
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    • pp.34-39
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    • 2007
  • Serial links via backplane channels suffer from severe signal integrity problems which are normally caused by channel imperfections, such as flat loss, frequency-dependent loss, reflection, etc. Particularly, the frequency-dependent loss causes ISI(Inter-Symbol-Interference) at signal waveforms. Therefore, adaptive equalizing techniques have been exploited in many products to facilitate the ISI problem. In this paper, we present an analog adaptive equalizer circuit designed in a $0.18{\mu}m$ CMOS process. It achieves 10Gb/s data transmission through a long 34-inch backplane channel(or transmission line). The post-layout simulations demonstrate $8ps_{p-p}$ jitter with 10mW power dissipation. The core of the adaptive equalizer occupies the area of $0.56mm^2$.

Influence of Gibberellin and Urea treatment on the Production of mulberry leaf and characteristic of silkworm (지베렐린과 요소의 처리가 상수의 수량 및 잠아의 실용형질에 미치는 영향)

  • 유근섭;오준식
    • Journal of Sericultural and Entomological Science
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    • v.9
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    • pp.27-34
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    • 1969
  • This study was conducted investigate the effect of Gibberellin and Urea on the growth of mulberry tree with the compound treatment, and the characteristic of silkworm when the mulberry leaves simply treated with GB and the compound treatment with GB and Urea were supplied. The results are as follows. 1. Mulberry tree A. The leaf weight per mulberry tree with the compound treatment of GB+ Urea was heavier in spring silkworm and the leaf yield was increased by 7% compared with the non-treatment plot. B. The growth of wattle, leaf length and leaf width was more accelerated in the compound treatment plot of GB+Urea, the single treatment plot of GB and Urea than th!: non-treatment plot in autumn silkworm, and there was observed an incredse yielding effect of 16% in GB+Urea plot, in 16% GB plot and 18% in Urea plot respectively as compared with th: non-treatment plot, hut yield per l000m unit of wattle length was the least in GB plot. C. In the composition of mulberry leaves of treatment, water and crude protein was increased in the compound treatment plot of GB + Urea and the single treatment plot of GB and Urea than the non-treatment plot, but dry matter and carbohydrate were decredsed. 2. Characteristics of Larva in spring silkworm A. The mortality ratio of 4 and 5 instar plot was equally high in the compound treatment plot of GB+ Urea and the pupation ratio of 4 instar plot was lower than other treatment plot. B. Although there was no significant difference observed in the cocoon weight of 10.000 1st-day worms in both 4 and 5 instar plots between each treatment plot, the single treatment plot of GB showed somewhat great than other treatment plots. C. There was no significant difference observed in the cocoon layer ratio between each treatment plot, but 4 instar plots was slightly higher than 5 instar plots. 3. Characteristics of Larva in Autumn silkworm A. The mortality ratio of the compound treatment plot of GB+ Urea and GB was higher than that of the nontreatment and single treatment plot of Urea. B. The pupation ratio of the single treatment plot of Urea was higher than that of the compound treatment plot of GB + Urea, and there was no significant difference observed between other treatment plot. C. The cocoon weight of 10.000 1st-day th instar worms was heavier in the single treatment plot of Urea than nontreatment plot, GB+Urea plot and GB plot. D. The cocoon layer ratio was no significant difference observed between each-treatment.

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Therapeutic Approach by Traditional Veterinary Medicine in a Case with Canine Myleomalacia: Case Report (척수연화증 개에서 전통 수의학적 방법을 이용한 치료 시도: 증례 보고)

  • Jun, Hyung-Kyou;Oh, Hyun-Uk;Lee, Hyun-Hwa;Han, Ji-Won;Lee, Byung-Kon;Park, Jin-Ho;Lee, Young-Won;Jeong, Seong-Mok;Kim, Duck-Hwan
    • Journal of Veterinary Clinics
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    • v.24 no.4
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    • pp.608-612
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    • 2007
  • A 4-year-old castrated male Cocker spaniel was referred with chief complaint of pelvic limbs paralysis and trembling. This dog was diagnosed as a case of myelomalacia complicated with intervertebral disc disease(IVDD) by radiography and magnetic resonance imaging(MRI). This patient was treated by injection-AP with apitoxin, herbal medicine and moxibustion. The acupoints such as GV02-1, GV04, GV11, GV12, GV13, GV14, BL11, BL18, BL23, BL25, BL28, GB21, HT07, KI03, LI04, LU07, SI03, SI06, ST36, ST38, ST39, ST40, ST41, GB30, GB31, GB34, Liv03, SP06 and trigger points($T1{\sim}T4\;and\;T9{\sim}L1$) were used for treatment. At the session 1, the dog could not stand and move the limbs. However, gradual improvement of clinical signs was observed after 7, 14 and 21 session of treatment. Although the clinical signs related to pelvic paralysis were not completely abolished with TVM methods, this case showed the marked improvement of clinical signs after 21 sessions of treatment. In conclusion, the present patient was a case with canine myelomalacia complicated with IVDD which showed not so complete but somewhat improvement by TVM method.

Development of SSR markers for classification of Flammulina velutipes strains (팽이버섯 (Flammulina velutipes) 계통의 분류를 위한 SSR 마커개발)

  • Woo, Sung-I;Seo, Kyoung-In;Jang, Kab yeul;Kong, Won-Sik
    • Journal of Mushroom
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    • v.15 no.2
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    • pp.78-83
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    • 2017
  • Microsatellite SSR markers were developed and utilized to reveal the genetic diversity of 32 strains of Flammulina velutipes collected in Korea, China, and Japan. From the SSR-enriched library, 490 white colonies were randomly selected and sequenced. Among the 490 sequenced clones, 85 (17.35%) were redundant. Among the remaining 405 unique clones, 201 (49.6%) contained microsatellite sequences. We used 12 primer pairs that produced reproducible polymorphic bands for four diverse strains, and these selected markers were further characterized in 32 Flammulina velutipes strains. A total of 34 alleles were detected using the 12 markers, with an average of 3.42 alleles, and the number of alleles ranged from two to seven per locus. The major allele frequency ranged from 0.42 (GB-FV-127) to 0.98 (GB-FV-166), and values for observed ($H_O$) and expected ($H_E$) heterozygosity ranged from 0.00 to 0.94 (mean = 0.18) and from 0.03 to 0.67 (mean = 0.32), respectively. SSR loci amplified with GB-FV-127 markers gave the highest polymorphism information content (PIC) of 0.61 and mean allele number of five, whereas for loci amplified with GB-FV-166 markers these values were the lowest, namely 0.03 and two. The mean PIC value (0.29) observed in the present study with average number of alleles (3.42). The genetic relationships among the 32 Flammulina velutipes strains on the basis of SSR data were investigated by UPGMA cluster analysis. In conclusion, we succeeded in developing 12 polymorphic SSRs markers from an SSR-enriched library of Flammulina velutipes. These SSRs are presently being used for phylogenetic analysis and evaluation of genetic variations. In future, these SSR markers will be used in clarifying taxonomic relationships among the Flammulina velutipes.

Design and fabrication of GaAs HBT ICs for 10-Gb/s optical communication system (10-Gb/s 광통신시스템을 위한 GaAs HBT IC의 설계 및 제작)

  • 박성호;이태우;김영석;기현철;송기문;박문평;평광위
    • Journal of the Korean Institute of Telematics and Electronics D
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    • v.34D no.3
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    • pp.52-59
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    • 1997
  • Design and performance of principal four ICs for the 10-Gb/s optical communication system are presented. AlGaAs/GaAs HBTs are basic devices to implement a laser diode driver, apre-amplifier, and a limiting amplifier, and GaInP/GaAs HBTs are used for an AGC amplifier. We fbricated 11.5-GHz LD driver, a pre-amplifier, and a limiting amplifier, an dGaInP/GaAs HBTs are used for an AGC amplifier. We fabricated LD deriver, 10.5 GHz pre amplifier, 7.2 GHz AGC amplifier, and 10.3 GHz limiting amplifier, optimized circuit design and the stabilized MMIC fabrication process.

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1-Gb/s Readout Amplifier Array for Panoramic Scan LADAR Systems (파노라믹 스캔 라이다용 1-Gb/s 리드아웃 증폭기 어레이)

  • Kim, Dayeong;Park, Sung Min
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.65 no.3
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    • pp.452-456
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    • 2016
  • In this paper, a dual-channel readout amplifier array is realized in a standard $0.18{\mu}m$ CMOS technology for the applications of panoramic scan LADAR systems. Each channel consists of a PIN photodiode with 0.9 A/W responsivity and a 1.0 Gb/s readout amplifier(ROA). The proposed ROA shares the basic configuration of the previously reported feedforward TIA, except that it exploits a replica input to exclude a low pass filter(LPF), thus reducing chip area and improving integration level, and to efficiently reject common-mode noises. Measured results demonstrate that each channel achieves $70dB{\Omega}$ transimpedance gain, 829 MHz bandwidth, -22 dBm sensitivity for $10^{-9}BER$, -34 dB crosstalk between adjacent channels, and 45 mW power dissipation from a single 1.8 V supply.