• Restorative Dentistry and Endodontics
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• 제40권1호
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• pp.68-74
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• 2015

Objectives: This study examined the effects of additional acid etching on the dentin bond strength of one-step self-etch adhesives with different compositions and pH. The effect of ethanol wetting on etched dentin bond strength of self-etch adhesives was also evaluated. Materials and Methods: Forty-two human permanent molars were classified into 21 groups according to the adhesive types (Clearfil SE Bond [SE, control]; G-aenial Bond [GB]; Xeno V [XV]; Beauti Bond [BB]; Adper Easy Bond [AE]; Single Bond Universal [SU]; All Bond Universal [AU]), and the dentin conditioning methods. Composite resins were placed on the dentin surfaces, and the teeth were sectioned. The microtensile bond strength was measured, and the failure mode of the fractured specimens was examined. The data were analyzed statistically using two-way ANOVA and Duncan's post hoc test. Results: In GB, XV and SE ($pH{\leq}2$), the bond strength was decreased significantly when the dentin was etched (p < 0.05). In BB, AE and SU (pH 2.4 - 2.7), additional etching did not affect the bond strength (p > 0.05). In AU (pH = 3.2), additional etching increased the bond strength significantly (p < 0.05). When adhesives were applied to the acid etched dentin with ethanol-wet bonding, the bond strength was significantly higher than that of the no ethanol-wet bonding groups, and the incidence of cohesive failure was increased. Conclusions: The effect of additional acid etching on the dentin bond strength was influenced by the pH of one-step self-etch adhesives. Ethanol wetting on etched dentin could create a stronger bonding performance of one-step self-etch adhesives for acid etched dentin.

• 한국작물학회:학술대회논문집
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• 한국작물학회 2022년도 추계학술대회
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• pp.32-32
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• 2022

Abaca (Musa textilis L. Nee) is a native Musa species from the Philippines known for its natural fiber. Abaca fiber a.k.a. Manila hemp extracted from its pseudostems is considered one of the strongest fibers in the world. This is used for commodities such as ropes, papers, and money bills. Abaca is vulnerable to pests and diseases such as the Abaca Bunchy Top Disease (ABTD) caused by Abaca Bunchy Top Virus (ABTV) and Banana Bunchy Top Virus (BBTV). Inosa, one of the varieties of abaca utilized in the Philippines, is highly susceptible to ABTD. In contrast, Pacol (Musa balbisiana L.), a close relative of abaca, is highly resistant to the same disease. Here, we report the sequencing and de novo genome assembly of both abaca var. Inosa and banana var. Pacol. A total of ~16 Gb and ~21 Gb raw reads for Inosa and Pacol, respectively, were generated using Pacbio Hifi sequencing method and assembled with Hifiasm. High-quality de novo assemblies of both Musa species with 99% recovered as per BUSCO analysis were obtained. The assembled Inosa genome has a total length of ~654 Mb and N50 of 7 Mb while Pacol has a total length of 527 Mb and N50 of 3 Mb which are close to their estimated genome size of ~638 Mb and ~503 Mb, respectively. The information that can be derived from the de novo assembled genomes would provide a solid foundation for further research in disease resistance and fiber quality improvement in abaca.

• 한방안이비인후피부과학회지
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• 제37권2호
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• pp.58-73
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• 2024

Objectives : This study was designed to review and analyze domestic research trends of Korean medicine treatment on otitis media, and present data for further research and treatment of otitis media. Methods : Two researchers used six search engines to search for papers on Korean medicine treatment for otitis media published from January 1, 2000 to December 31, 2023. A total of 16 papers were searched, and bibliographic information, main and accompanying symptoms, treatment period, treatment method, evaluation scale, and treatment results of each study were analyzed. Scottish Intercollegiate Guidelines Network was used to evaluate the evidence level. Results : The most common otitis media symptom was hearing loss (12 times). The most frequently mentioned herbs were Ledebouriella seseloides (22 times) and Angelica gigas (20 times), which are the ingredients of the most commonly used prescriptions, Hyunggyeyungyo-tang (5 times), Takrisodok-yeum (4 times), and Bojungikgi-tang (3 times). All the clinical trial papers were conducted on Kamihyunggyeyungyo-tang, which showed improvement in otitis media-related indicators. The most frequently mentioned meridians were the Triple Energizer (44 times), Clinical trials were conducted on the Triple Energizer, the Gall Bladder, and the Small Intestines meridians. The most frequently used acupoints were SI19 (10 times), TE21 (9 times), TE17 (9 times). In clinical trials, acupuncture treatment with TE05, GB15, TE06, SI05, GB38, and KI02 showed a significant improvement in otitis media symptoms. Conclusions : It is believed that more efficient otitis media treatment and follow-up research can be performed by using the above-mentioned research results.

• Journal of Acupuncture Research
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• 제26권2호
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• pp.103-123
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• 2009

Objectives : The aim of this study is to review RCTs of acupuncture treatment for neck pain and to establish standards of acupuncture treatment for neck pain. Methods : We searched articles in Pubmed using ICD 10. Study quality was assessed using the FEAS and Jadad score. Results and Conclusions : Three review studies and nineteen clinical trials were searched and reviewed. Among the nineteen clinical trials reviewed, positive outcome was reported in thirteen studies. Most frequently used meridians were GB, BL, SI, GV and LI, The most frequently used acupuncture points were $GB_{20}$, $GB_{21}$, $LI_4$, $BL_{10}$, $GV_{14}$ and $SI_3$. More than two needles were inserted in the studies and needle retention time was more than 10 minutes. The most frequently used needle length was 40mm, and diameter was 0.25mm and 0.30mm. The mean number of treatment sessions were more than 10 times. Frequency of treatment was more than once a week, And treatment duration was more! than 5 weeks. The total FEAS scores ranged from 3 to 15.5, and the mean value was 9.39. Jadad score ranged from 2 to 5, and the mean value was 3.42. The number of studies scoring over three points on the Jadad scale was sixteen.

• Korean Journal of Acupuncture
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• 제22권3호
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• pp.137-156
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• 2005

Objectives : Cnidium officinale(CO) has been used for medication for stroke in the Oriental Medicine. So this study was planned to investigate the effects of CO on the focal ischemia-induced by Middle Cerebral Artery Occlusion(MCAO) in rats Materials and methods : The focal ischemia was induced by MCAO. CO extracts through oral administration and herbal acupuncture at GB2l was carried out during 3 weeks after focal ischemia-induced. Eight-arm radial maze was used for the behavioral task. For the neuroprotective effect of CO, we investigated AchE, ChAT, and NGF-expression by immnohistochemical method. Results : The error rate in the eight-arm radial maze task was significantly decreased in normal group compared to control group on 1-6days, OA-CO1(CO oral administration, 0.8g/kg) group on 1-6days, OA-CO2(CO oral administration, 1.6g/kg) group on 1-3,5,6days, HA-CO1(CO herbal acupuncture, 0.016g/kg) group on 2,3,6days, HA-CO2(CO herbal acupuncture, 0.008g/kg) group on 1-3,5,6days. The rate of correct choice was significantly increased in OA-CO1, HA-CO2. The density of neurons in the hippocampal CA1 was the most increased in OA-CO1, HA-CO1, HA-CO2. The density of ChAT in the hippocampal CA1 was increased in OA-CO1, HA-CO2. The density of ChAT in the hippocampal CA1 was significantly increased in OA-CO1, HA-CO2. The density of NGE in the hippocampal CAI was significantly increased in OA-CO1, OA-CO2, HA-CO2. Conclusions : These results suggest that CO oral administration with 0.8g/kg and CO herbal acupuncture with 0.008g/kg might be used as a regulator of cell death of cholinergic system induced by stroke.

• 한국환경농학회지
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• 제32권4호
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• pp.287-293
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• 2013

본 시험은 녹비작물의 토양 혼입시기가 벼의 수량에 미치는 영향을 조사하기 위하여 녹비작물을 벼 이앙 25일전, 18일전 및 11일전에 각각 혼입하였으며, 혼입시기별 녹비보리 및 헤어리베치의 biomass와 무기성분 함량 및 양분공급량을 조사하였고, 각각의 처리구에서 벼의 수량을 조사하였다. 녹비보리 및 헤어리베치의 biomass는 토양으로의 혼입이 늦어질수록 biomass는 증가하였고, T-N, T-P 및 $K_2O$의 함량은 점차 감소하는 경향이었지만 그 차이는 미미하였다. 녹비보리 및 헤어리베치의 N, $P_2O_5$ 및 $K_2O$의 공급량은 다소 차이는 있지만 전반적으로 5월 20일에 혼입한 LPM3 처리구에서 가장 많았다. 벼의 간장, 수장 및 이삭수는 녹비작물의 혼입시기별 처리구에 상관없이 비슷한 경향으로 control 처리구에 비해 생육이 좋았지만, 녹비작물의 토양 혼입시기에 따른 유의성은 없었다. 벼의 총립수, 천립중 및 수량은 control 처리구에 비해 녹비보리 및 헤어리베치 처리구에서 많았으며, 토양 혼입시기에 상관없이 벼의 수량은 control 처리구 대비 녹비보리 혼입 처리구에서 2~3%, 헤어리베치 혼입 처리구에서 4~5%의 증수효과를 보였다.

• 대한한방부인과학회지
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• 제28권2호
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• pp.193-203
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• 2015

목 적: 상열감과 발한과다는 갱년기 증후군의 대표적 증상이다. 본 연구에서는 약침을 이용한 수화조절법을 사용하여 갱년기 증후군 환자의 상열감과 발한과다 증상 감소에 유의한 효과를 얻어 이를 보고하고자 한다. 방 법: 황련해독탕 약침을 양측 견정(GB21), 풍지(GB20) 혈에 각각 0.1 cc씩 총 0.4 cc를 주입하고, BUM(웅담, 우황, 사향)약침은 전중(CV17), 중완(CV12), 기해(CV16)혈에 각각 0.05cc씩 총 0.15cc를 주입한다. 시술은 매일 시행하였으며, 증상에 관하여 상열감점수(Hot flush score), 발한에 대한 Visual Analogue Scale(VAS) 및 발한 부위를 기록하여 증상변화 정도를 평가하였다. 결 과: 1번 증례는 약침 수화조절법 시행 후 상열감점수는 24에서 4로, 발한에 관한 VAS는 7에서 2로 감소하였다. 상열감 및 발한과다 증상의 감소와 더불어 손발이 화끈거리는 증상도 함께 감소되었다.2번 증례는 약침 수화조절법 시행 후 상열감점수가 28에서 2로, 발한에 관한 VAS는 10에서 3으로 감소하였다. 상열감 및 발한과다 증상의 감소와 더불어 불안, 우울, 분노 증의 정서적 증상도 70%정도 감소하였다.3번 증례는 약침 수화조절법 시행 후 상열감점수가 8에서 1로, 발한에 관한 VAS는 6에서 1로 감소하였다. 상열감 및 발한과다 증상의 감소와 더불어 두통, 가슴 답답함 등의 증상도 함께 소실되었다.모든 증례에서 발한 부위의 변화는 없었다. 결 론: 본 증례에서 약침을 이용한 수화조절법은 갱년기 상열감과 발한과다 증상을 감소시키는 효과가 있었으며 부가적으로 호소하던 증상도 감소하거나 소실되는 효과가 있었다. 그러므로 약침을 이용한 수화조절법은 상열감과 발한과다를 호소하는 갱년기 증후군 환자에게 효과적인 치료법이라 사료된다.

• 한국가금학회지
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• 제49권4호
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• pp.255-264
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• 2022

본 연구는 인삼 부산물 첨가 급여가 고온에서 사육된 육계의 생산성, 장기발달, 혈액생화학적 특성, 면역반응 및 스트레스 지표에 미치는 영향을 구명하기 위해 실시하였다. 총 100수의 1일령 수컷 병아리(Ross 308)를 공시하여 5주간 육계용 실험 케이지에서 사육하였다. 첫 일주일간은 동일한 초기사료를 급여하였고, 2주차부터 대조구(CON), 진생베리 0.5% 첨가(GB1), 진생베리 1.0% 첨가(GB2), 인삼 잎·줄기 0.5% 첨가(GLS1), 인삼 잎·줄기 1.0% 첨가(GLS2), 총 5개의 시험구에 임의배치 하였다. 환경 온도는 매일 오전 9시부터 오후 5시까지 32±1℃, 이후 시간은 28±1℃를 유지하였고, 사료와 물은 자유채식 시켰다. 생산성은 처리구들 간에 유의한 차이를 보이지 않았으나, 사육후기(21~35일)와 전 기간(7~35일)에는 증체량이 모든 첨가급여구들에서 CON보다 높은 경향을 보였다. 혈액 생화학적 특성은 빌리루빈 수치를 제외하고는 시험구들 간에 유의한 차이가 없었다. 혈청 면역글로불린과 코르티코스테론 수치는 시험구들 간에 유의차가 나타나지 않았으나, 코르티코스테론 함량이 CON보다 첨가급여구들에서 첨가수준에 따라 감소하는 경향이 나타났다. 결론적으로, 인삼 부산물의 사료 내 첨가급여는 육계의 생산성 및 각종 생리지표에 부정적인 영향을 미치지 않으면서 성장기 육계의 고온 스트레스 저감에 긍정적인 효과가 기대되어 향후 지속적인 관심과 후속 연구가 필요할 것으로 사료된다.

• 기계저널
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• 제34권9호
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• pp.711-719
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• 1994

수퍼컴퓨터의 발전속도는 반도체 및 메모리의 급진적인 개발로 인해 날로 가속화되어 가고 있다. 90년대 말에는 화합물반도체 \ulcorner 신소재의 등장으로 연산속도가 더욱 빨라질것으로 추정 되며 메모리도 400GB의 용량을 가진 수퍼폼퓨터가 출현할 것으로 예측된다. 1993년 1월에 Hitachi는 세계 최초로 원자규모(한원자에 한비트) 메모리 개발에 성공하여 21세기에 실용화를 목표로 하고 있다. UR의 타결과 더불어, 각국의 무역장벽이 높아지고 지적 소유권 보호가 강 화됨에 따라 첨단기술의 도입이 점차 어려워지는 현재 시점에서, 급속히 발전되어 가는 최첨단의 수퍼컴퓨터를 효과적으로 활용해야 할 필요성이 더욱 증가하고 있다. 따라서 수퍼컴퓨터의 활용 및 첨단 CAE 기술의 개발을 통하여 국내 연구개발 수준을 선진국 대열로 높이고, 국내 산업 계의 고품질 신제품 개발 및 생산성 향상을 유도하여 국산제품의 국제 경쟁력을 제고해야 할 것이다.

• 한국임상수의학회지
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• 제21권1호
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• pp.49-51
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• 2004

A four-year-old female Pekingese dog was presented with intermittent ambulatory hindlimb lameness and severe back pain. The course of the disease was acute and static and 5 days passed by until presentation. In neurological examination, severe back pain and slightly decreased proprioception in right hindlimb were shown. In radiographic examination, radiopacity was increased at T10-11 intervertebral disc space. According to the history taking, neurological examination and radiographic examination, it was tentatively diagnosed as intervertebral disc disease (IVDD). Conservative treatment was performed including cage rest, medication with prednisolone and traditional acupuncture. Acupoints were GV-6, GV-7, BL-18, BL-19. BL-40 and GB-34. Dry needlings rested for 20 minutes. Just after the first acupuncture treatment back pain was significantly decreased. With additional acupuncture treatment, all the clinical signs were not observed. It is considered that conservative therapy including traditional acupuncture, medication and cage rest might be the first choice of therapeutic method for Grade I or II IVDD in dogs.