• Journal of Acupuncture Research
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• 제27권4호
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• pp.127-135
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• 2010

Objectives : The main purpose of this study is to evaluate effects of acupuncture at Fengchi($GB_{20}$) and Houxi($SI_3$) for acute headache due to whiplash injury. Methods : This study was observed among 50 patients with acute headache due to whiplash injury who admitted to Bundang oriental medicine hospital of Dongguk University from June 16, 2009 to January 31, 2010. These patients were divided into two groups; One was control group that was acupunctured at general acupuncture points except Fengchi($GB_{20}$), Houxi($SI_3$)(Control group) and the other was acupunctured at Fengchi($GB_{20}$), Houxi($SI_3$) with general acupuncture points(Experimental group). Each patient was acupunctured once a day. The effect was assessed through self-rating headache index. Results & Conclusions : As a result of evaluation by using self-rating headache index, pain score at 8th day declined in both groups. But they were not difference between two groups at 8th day.

• 한국조리학회지
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• 제17권5호
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• pp.218-230
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• 2011

본 연구는 식이섬유가 풍부한 고아미 소비를 증가하고자 밀가루 대신 고아미 쌀가루로 모닝빵을 제조하고자 하였다. 고아미 가루의 입도는 5분, 10분, 15분, 20분 분쇄기에 갈아 달리하였으며, 밀가루반죽과 같은 경도를 찾기 위해 물의 양을 달리하여 고아미 반죽의 경도를 측정한 결과 최적의 물의 양은 119 mL~218 mL 이었다. GB4는 60분경과 발효율이 가장 좋았으며, 모닝빵의 부피는 밀가루 모닝빵이 가장 컸고, 경도는 밀가루 모닝빵과 GB4가 비슷하였으며, 명도는 밀가루빵이 가장 밝았다. 관능검사결과 밀가루빵이 가장 선호되었고, 고아미 모닝빵 중에서는 15분 분쇄한 가루로 만든 GB3와 GB4가 선호되었다.

• Korean Journal of Acupuncture
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• 제25권4호
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• pp.119-132
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• 2008

Objectives : To compare the effects of low-frequency electro-acupuncture (EA) stimulation at left and right GB34s on hepatotoxicity in $CCl_4$-intoxicated rats. Methods : Rats were injected with $CCl_4$ and treated with 2 Hz electro-acupuncture (EA) at left and right GB34s for 15 minutes 3 times per week, for 10 weeks. Holder group, injected with $CCl_4$ and strained in a cylinder for same period as the EA group, was established to compare the hepatotoxicity against the two electroacupuncture groups. To estimate the effects of EA on hepatotoxicity in rats, body weight, liver weight and liver index were measured. Biochemical assays for serum ALT, AST, ALP and total cholesterol ; hematological analysis for RBC, WBC, PLT, hemoglobin, lymphocytes, neutrophils and monocytes ; and histology analysis of liver tissue were also performed. Results : Lymphocyte level in blood was significantly decreased by $CCl_4$-intoxication, and increased by low-frequency electroacupuncture applied on both left and right GB34s. Low-frequency EA applied on right and left GB34s significantly reduced serum ALT and AST, both of which had been increased by $CCl_4$-intoxication. Conclusion : Low-frequency electroacupunctures at both left and right GB34s have hepatoprotective effects on $CCl_4$-induced liver damage in rats. However, no significant differences were found between the effects of EAs at left and right GB34s.

• Korean Journal of Acupuncture
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• 제27권1호
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• pp.107-123
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• 2010

Objective & Methods: The purpose of this study is to investigate the effects of Artemisiae Capillaris Herba herbal-acupuncture (ACH-HA) at GB34 (Yangleungchean) on hyperlipidemia induced with alloxan injection and high fat diet in rats. The author performed several experimental items to analyze the levels of various components and enzymes in serum, liver, as well as the histological changes of liver and aorta. Results: 1. ACH-HA solution increased the DPPH radical scavenging activity in rat liver cells. 2. ACH-HA at GB34 significantly decreased the levels of serum total cholesterol, low-density lipoprotein (LDL)-cholesterol, free cholesterol and atherogenic index (AI), while significantly increased the ratios of high-density lipoprotein (HDL)/total cholesterol and phospholipid/total cholesterol in hyperlipidemic rats. 3. ACH-HA at GB34 significantly decreased serum aspartate aminotransferase (AST) level in hyperlipidemic rats. 4. ACH-HA at GB34 significantly increased hepatic glutathione (GSH) activity in hyperlipidemic rats. Conclusion: From the above results, it is suggested that ACH-HA at GB34 may have therapeutic and preventive effects on hyperlipidemia.

• Journal of Acupuncture Research
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• 제26권4호
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• pp.79-90
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• 2009

Objectives & Methods : The purpose of this study is to observe the effects of Puerariae Radix Herbal-acupuncture at $GB_{34}$(Yangleungcheon) on hyperlipidemia in rats. The author made several items to compare body-weight of the rats, weight of its liver, serum, enzymes in liver as well as the histological changes in each group. Results : 1. In the Puerariae Radix herbal-acupuncture group, there was a significant improvement of the levels of total cholesterol, HDL-cholesterol, atherosclerosis index and phospholipid in serum as compared with the control group but there was no significant difference as compared with the NP or saline group. 2. There was a significant improvement of HMG-CoA reductase activity and catalase level in Puerariae Radix herbal-acupuncture group as compare with the control group, the NP group and the saline group. 3. The pathohistological changes of liver and aorta was suppressed in the Puerariae Radix herbalacupuncture group than the control group. Conclusions : From the above results, it is suggested that Puerariae Radix herbal-acupuncture at GB34 has a therapeutic effect on hyperlipidemia.

• Journal of Periodontal and Implant Science
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• 제23권2호
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• pp.352-357
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• 1993

The purpose of the present study was to evaluate and compare the periodontal conditions of distally extending cantilever bridges(CB) and removable patial dentures(RPD). 78 patients treated with removable partial dentures were divided into 2 groups; bilateral free-ending (type 1) and unilateral free-ending(type 2). 43 patients treated with distally extending cantilever bridges were divided into 4 groups according to position of missing molars and number of including abutment tooth (or teeth) (type 1-4). Prosthodontic status of the abutment teeth were assessed; overcontoured crown, overhanged margin, embrasure closure, and others. Their Periodonted status were assessed with Plaque Index Gingial Index(GI) Sulcus bleedy Index (SBI), Tooth mobility(TM) & Posher depth(PPD). 35.9% of RPD group and 38.1 of CB grouphad disconfort on mastication with prosthetics. 16.7% of RPD group and 6.1% of CB group showed on opposing sites. Overhanged margins were 58.3% for RPD group and 86.6% for GB group. 45.5% of RPD group and 72% of CB group had embrasure closure on the abutment teeth. 30.5% of GB group had oversized pontic. Gb group showed much higher clinical parameters than RPD groups, but statistically not significant. Type 2 of RPD group showed lower GI and SBI, but statistically not significant. Type 3 of CB group showed the highest GI and SBI and type 2 showed the highest tooth mobility, but there is no differences between the same type of groups. In conclusion, only minor differences in periodontal conditions were recorded in RPD and CB group.

• 대한한방내과학회지
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• 제19권1호
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• pp.22-38
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• 1998

This study was to investigate the hepatoprotective and anticirrhotic effects of Ganyeumilhobang(GIE) on the acute and chronic liver injury induced by various agents. Chronic liver injury induced by dimethylnitrosamine(DMN) ; a new experimental model for cirrhosis and the intraperitoneal injection of dimethylnitrosamine in the rat. Acute liver njury induced by carbon tetrachloride$(CCl_4)$ and D-galactosamine ; a experimental model for acute liver injury, the administration of $CCl_4$ and the intraperitoneal injection of D-galactosamine in the rat. The development of fibrosis and acute liver injury by the three prescriptions were examined by the chemical analysis of AST, ALT, prothrombin time and hydroxyproline. The results obtained were as follows. 1. The increasing level of hydroxyproline volume induced by DMN in mice was decreased by the oral administration of GIB. 2. The degree of histological fibrosis and hepatic inflammatory cell infiltration induced by $CCl_4$ decreased by the oral administration of GIB. 3. The increase of senun AST and ALT of mice with acute liver damage induced by $CCl_4$ and D-galactosamine was inhibited by the administration of GIB. 4. The prolongation of prothrombin time(seconds) of mice acute liver damage induced by $CCl_4$ was shortened by the oral administration of GIB. 5. The liver of mice was hepatectomized partial1y after the oral administration of GIB. The mitotic index(% of nuclei), weight of liver, contents of protein, RNA and DNA synthesis of the liver tissue were increased by the oral administration of GIB.

• 한국광학회지
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• 제16권5호
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• pp.417-422
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• 2005

광 펄스가 대기 채널을 통해 전송될 때, 광 펄스는 대기 교란에 의해 감쇄되고 퍼지게 된다. 이러한 펄스 퍼짐이 인접 펄스간의 부호 간 간섭을 일으키고, 그 결과 인접한 펄스들은 중첩이 되어 비트전송률 및 무중계 전송거리를 제한하게 된다. 이에, 본 논문에서는 시간적 모멘트 함수를 이용하여 대기 교란상태에서 부호 간 간섭을 교란 상태를 나타내는 굴절률 구조상수로 구하고, SONET 광 전송방식에서 교란상태에 따른 부호 간 간섭을 수치해석하였다. 그 결과, 교란 정도가 심할수록 부호 간 간섭은 OC-192(9.953 Gb/s) 시스템 이하의 전송률에서는 점차적으로 증가하나, OC-768(39.813 Gb/s) 시스템 이상의 전송률에서는 급격히 증가 후 서서히 수렴함을 알 수 있었다. 또한, OC-48(2.488 Gb/s) 시스템에서는 어떠한 교란상태 하에서도 10 [km] 정도까지 정확한 정보 전송이 가능하나, 100 Gb/s 시스템에서는 $10^{-14}[m^{-2/3}]$ 이상, OC-768 시스템에서는 $10^{-13}[m^{-2/3}]$이상, OC-192 시스템에서는 $10^{-12}[m^{-2/3}]$ 이상의 교란상태에서 심한 부호 간 간섭이 발생하여 정확한 정보 전송이 불가능함을 알 수 있었다.

• Journal of Animal Science and Technology
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• 제61권2호
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• pp.55-60
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• 2019

Colibacillosis is one of the major health problems in young piglets resulting in poor health and death caused by Escherichia coli producing F18 pili and Shiga toxin 2e. It is pivotal to reduce colibacillosis in weaned piglets to enhance production performance. In this study, we evaluated synbiotics as the gut health improvement agents in the mouse model challenged with Shiga toxin-producing E. coli (STEC) isolated from piglets. Prebiotic lactulose was formulated with each $5.0{\times}10^6CFU/mL$ of Pediococcus acidilactici GB-U15, Lactobacillus plantarum GB-U17, and Lactobacillus plantarum GB 1-3 to produce 3 combinations of synbiotics. A total of 40 three weeks old BALB/c mice were randomly assigned to 4 groups (n = 10): a control group and 3 synbiotics treated groups. Each treatment groups were daily administrated with $5.0{\times}10^6CFU/mL$ of one synbiotics for the first week, and every 3 days during the second week. All the mice were challenged with $8.0{\times}10^8CFU/mL$ of STEC 5 days after animals began to receive synbiotics. Mice treated with synbiotics based on Pediococcus acidilactici GB-U15 and Lactobacillus plantarum GB-U17 significantly improved daily weight gain compared to mice in other groups. While mice treated with GB-U15 showed better fecal index, no significant differences were observed among groups. Gross lesion and histopathological evaluations showed that mice treated with GB-U15 moderately improved recovery from STEC infection. In conclusion, our results suggest that the synbiotics formulated with lactulose and Pediococcus acidilactici GB-U15 have potential benefits to prevent and improve colibacillosis in weaned piglets.

• Journal of Acupuncture Research
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• 제32권3호
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• pp.1-13
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• 2015

Purpose : This research was conducted to investigate the effect of sweet bee venom pharmacopuncture and low level laser acupuncture on paw edema, pain index, anti-inflammatory factor, AST, ALT and complete blood cell count of a rat model with Complete Freund's Adjuvant-induced arthritis. Methods : Five experimental groups were formed with each consisting of six rats: normal group, control group, sweet bee venom pharmacopuncture group, lower level laser acupuncture group, and sweet bee venom pharmacopuncture, lower level laser acupuncture group. The experimental model of arthritis was induced by two injections of Freund's adjuvant into the left knee joint of Sprague Dawley(SD) rats. The second injection of Freund's adjuvant was given ten days after the first one. Ten days later, sweet bee venom pharmacopuncture and low level laser acupuncture were administered separately or together by assigned groups at $GB_{34}$ and $GB_{39}$ of rats twice a week for a total of six times. Thereafter, edema rate, pain index, tumor necrosis factor-${\alpha}$, interleukin-6, aspartate aminortansferase, alanine aminotransferase and complete blood cell count were measured. Results : We noticed synergic effects of sweet bee venom pharmacopuncture and low level laser acupuncture according to the results of the paw edema and Von Frey pain index. The sweet bee venom pharmacopuncture(BVA) and sweet bee venom pharmacopuncture+ low level laser acupuncture(BVA+LLA) groups experienced a more significant effect when compared with the control group. Conclusions : These results suggest that Sweet Bee Venom Pharmacopuncture and low level laser acupuncture at GB34 and GB39 have a significant anti-inflammatory effect on Freund's adjuvant arthritis in rats.