• Microbiology and Biotechnology Letters
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• v.23 no.2
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• pp.220-228
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• 1995

For polyhydroxyalkanoic acid (PHA) production, several microorganisms were isolated from sewage sludge. One of them, GB-77 strain, was chosen from its PHB/HV copolymer production on only fructose without cosubstrate. The isolated strain GB-77 was identified as the genus Alcaligenes. Optimal temperature and pH for cell growth were 36C and 6.8. Optimal medium composition was 10 g/l of fructose and 5 g/l of polypeptone, 1 $\times$ 10$^{-2}$M Na$^{2}$HP0$^{4}$, 1.3 $\times$ 10$^{-2}$M KH$^{2}$PO$^{4}$. To investigate the optimal condition for polyhydroxyalkanoic acid production two-stage culture technique was used; first stage for cell growth and second stage for PHA production on unbalanced growth conditions. Optimal conditions for high PHA production were C/N ratio 50, temperature 36$\circ$C and pH 6.8. To overcome fructose inhibition on cell growth, intermittent feeding fed-batch culture technique was used. Total cell concentration was 17.4 g/l with 9.1 g/l of PHA. The purified PHA was identified PHB/HV copolymer by NMR analysis.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2002.07b
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• pp.1022-1025
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• 2002

This paper presents the reliability of planar InP/InGaAs avalanche photodiodes (APD's) with recess etching, which is very crucial for the commercial 10-Gb/s optical receiver application. A versatile design for the planar InP/InGaAs APD's and bias-temperature tests to evaluate long-term reliability at temperature from 200 to $250^{\circ}C$. The reliability is examined by accelerated life tests by monitoring dark current and breakdown voltage. The lifetime of the APD's is estimated by a degradation activation energy. Based on the test results, it is concluded that the planar InP/InGaAs APD's with recess etching shows the sufficient reliability for practical 10-Gb/s optical receivers.

• Korean Journal of Optics and Photonics
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• v.7 no.4
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• pp.428-433
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• 1996

We have demonstrated 200 km non-dispersion shifted fiber(NDSF) transmission of 10 Gb/s signal by using mid-span spectral inversion(MSSI) method as a dispersion compensation technique. We have used four-wave mixing process in dispersion shifted fiber(DSF) to generate a spectrum inverted signal. The spectral inversion efficiency of -26.7dB and signal to noise ratio of 23.0 dB have been achieved. The measured sensitivities at $10^{-9}$ bit error rates (BER) were -28.0 dBm in back to back configuration and -27.0 dBm after transmission of 200 km NDSF.

• Proceedings of the IEEK Conference
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• 2003.07b
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• pp.979-982
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• 2003

Due to the differential transmission technique and low voltage swing, LVDS has been widely used for high speed transmission with low power consumption. This paper presents the design and implementation of interface circuits for 1.5Gb/s operation in 0.35um CMOS technology. The interface circuit ate fully compatible with the low-voltage differential signaling(LVDS) standard. The LVDS proposed in this paper utilizes a sense amplifiers instead of the conventional differential pre-amplifier, which provides a 1.5Gb/s transmission speed with further reduced driver output voltage. Furthermore, the reduced driver output voltage results in reducing the power consumption.

• Proceedings of the Korea Electromagnetic Engineering Society Conference
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• 2002.11a
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• pp.394-397
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• 2002

A design study of phase detectors for the 2.5 Gb/s CDR circuit using a standard 0.18-${\mu}{\textrm}{m}$ CMOS process has been performed. The targeted CDR is based on the phase-locked loop and thus it consists of a phase detector, a charge pump, a LPF, and a VCO. For high frequency operation of 2.5 Gb/s, phase detector and charge pump, which accurately compare phase errors to reduce clock jitter, are critical for designing a reliable CDR circuit. As a phase detector, the Hogge phase detector is selected but two transistors are added to improve the performance of the D-F/F. The charge pump was also designed to be placed indirectly input and output.

• Proceedings of the IEEK Conference
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• 2001.06a
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• pp.375-378
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• 2001

A 640Gb/s very advanced ATM switching system using 0.25um CMOS VLSI, 40 layer ceramic MCM and 10Gb/s, 8 wavelength 8$\times$8 optical WDM interconnection has been fabricated. To break though the interconnection bottleneck, optical WDM interconnection is used. It has 20Gb/s 8 wavelength 8$\times$8 interconnection capability. It realizes 640Gb/s interconnections within a very small size. Preliminary tests show that 800b1s ATM switch MCM and optical WDM interconnection technologies can be applied to future high speed broadband networks

• Proceedings of the KSMRM Conference
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• 2003.10a
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• pp.85-85
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• 2003

Purpose： To investigate whether or not acupuncture of GB34 produces a significant response of the modulation of somatomotor areas by functional magnetic resonance imaging (fMRI) study. Materials and methods： The acupoint, GB34, located in the back of the knee, is known to be effective in recovering motor function after stroke. Using 3T MRI scanner, functional MR imaging of the whole brain was peformed in 12 normal healthy subjects during two stimulation paradigms; acupuncture manipulation on GB34 and sham points. This study investigates the activation of the motor cortex elicited by a soft and an intensified stimulation of GB 34.Three different paradigms were carried out to detect any possible modulation of the Blood Oxygenation Level Dependent (BOLD) response in the somatomortor area to motor stimulation through acupuncture.

• Korean Journal of Optics and Photonics
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• v.10 no.2
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• pp.169-173
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• 1999

We have experimentally investigated the eye margin characteristics of intensity modulated 10Gb/s NRZ signals in optically amplified systems depending on optical signal-to-noise ratio and chromatic dispersion. For the practical system application, the minimum optical signal-to-noise ratio was 25 dB. We utilized the negative chirped transmitter and a dispersion compensation fiber to compensate the chromatic dispersion in single mode fiber. We found the optimum eye opening and receiver sensitivity in case of the residual dispersion of 0~+935 ps/nm.

• Proceedings of the Optical Society of Korea Conference
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• 2001.02a
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• pp.176-177
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• 2001

최근에 매우 짧은 펄스를 이용한 RZ 포맷의 고속 광전송이 소개되었다. 컴퓨터 시뮬레이션을 통하여 이 포맷이 40Gb/s 전송에 유효하다는 것이 보여졌으며, 또한 실험을 통하여 이 포맷이 광섬유에서의 SPM에 저항성을 갖는다는 것of 보여졌다. 이 후 몇 편의 논문을 통하여 160Gb/s,300km(3$\times$100km)전송, 40Gb/s, 720km(6$\times$120km)전송 등이 보고되었다. 이 새로운 포맷에서는 짧은 펄스를 사용하므로 광신호가 고유의 정보량이 요구하는 최소한의 것보다 넓은 대역폭을 차지하게 되며 이는 광섬유의 분산과 상호작용을 하여 광전송중 광섬유의 비선형성에 의한 신호의 왜곡을 줄이는 역할을 하게 된다. (중략)

• YAKHAK HOEJI
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• v.60 no.1
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• pp.15-20
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• 2016

Globotriaosylsphingosine (lyso Gb3) is considered as one of the biomarkers for Fabry disease. A rapid and simple UPLC-MS/MS method was developed for the determination of reliable biomarker, lyso Gb3. Total analytical procedure takes only 15 min including sample preparation and MS/MS analysis. Limit of detection was 0.85 ng/ml (S/N=3). The calibration curve was linear over the range of 2.0~400.0 ng/ml ($R^2=0.9999$). Inter-day and intra-day assay accuracy were 93.4~100.6% (RSD, 0.6~6.0%) and 97.5~100.7% (RSD, 3.6~5.2%). Absolute recoveries of 97.6~98.6 showed excellence of a new analytical method. The method was applied to human and mice urines, proved the suitability for the quantification of lyso-Gb3 for screening, diagnosis and therapeutic monitoring of Fabry disease patients.