• Asian-Australasian Journal of Animal Sciences
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• 제32권3호
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• pp.395-404
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• 2019

Objective: Wheat bran (WB) and rice bran (RB) are the agricultural by-products used as poultry feed in many developing countries. However, their use for poultry feed is limited due to high fiber and the presence of anti-nutritional substances (e.g. ${\beta}-glucans$). The objective of this study was to develop a method to improve the quality of those brans by reducing the fiber content. Methods: A two-step fermentation method was developed where the second fermentation of first fermented dry bran was carried out. Fermentation was performed at a controlled environment for 3 h and 6 h (n = 6). The composition of brans, buffer solution and rumen liquor was maintained in a ratio of 1:2:3, respectively. Brans were analyzed for dry matter, crude fiber (CF), acid detergent fiber (ADF), neutral detergent fiber (NDF), and acid detergent lignin (ADL) content. Celluloses and hemicelluloses were calculated from the difference of ADF-ADL and NDF-ADF, respectively. Samples were compared by two-factor analysis of variance followed by Tukey's multiple comparison tests (p<0.05). Results: CF %, ADF % and cellulose tended to decrease and NDF % and hemicellulose content was reduced significantly (p<0.05). After the 1st fermentation step, NDF decreased $10.7%{\pm}0.55%$ after 3 h vs $17.0%{\pm}0.78%$ after 6 h in case of WB. Whereas, these values were $2.3%{\pm}0.30%$ (3 h) and $7.5%{\pm}0.69%$ (6 h) in case of RB. However, after the 2nd fermentation step, the decrease in the NDF content amounted to $9.1%{\pm}0.72%$ (3 h), $17.4%{\pm}1.13%$ (6 h) and $9.3%{\pm}0.46%$ (3 h), $10.0%{\pm}0.68%$ (6 h) in WB and RB, respectively. Cellulose and hemicellulose content was reduced up to $15.6%{\pm}0.85%$ (WB), $15.8%{\pm}2.20%$ (RB) and $36.6%{\pm}2.42%$ (WB), $15.9%{\pm}3.53%$ (RB), respectively after 2nd fermentation of 6 h. Conclusion: Two-step fermentation process improved the quality of the brans for their use in poultry feed.

• 생물환경조절학회지
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• 제18권3호
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• pp.244-252
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• 2009

본 연구는 우리나라와 네덜란드의 상업적인 온실에서 파프리카의 전체 재배기간 동안 시설 내 외부 기상환경을 비교 분석함으로써 양국간 생산량 차이 원인 분석을 함으로써 우리나라 파프리카의 시설내부 재배환경조건을 최적화하기 위한 기초자료 확보를 위하여 이 연구를 수행하였다 두 온실 모두 'Derby'를 공시하여 우리나라는 3.75주/$m^2$(2 stems), 네덜란드는 2.5주/$m^2$(3 stems), 1.875주/$m^2$(4 stems)로 암면에 수경재배 하였다. 두 온실모두 재식주수는 상이하였지만, 줄기밀도는 7.5m$^2$/stems로 같았다. 양국의 파프리카 주별 생장량은 크게 차이가 나지 않았으나, 전체 마디 대비 수확마디는 네덜란드가 우리나라에 비해 두 배 이상 높았다. 전체 재배기간 동안 일중 평균 광량은 우리나라 14.5MJ/$m^2$/day, 네덜란드 12.1MJ/$m^2$/day로 우리나라가 19.8% 높았다. 시설내부 24시간 평균온도는 우리나라 $21.6^{\circ}C$, 네덜란드 $21.2^{\circ}C$로 비슷한 경향을 보였지만, 우리나라의 시설내부 온도관리가 변화폭이 심하였다. 전체 작기의 시설내부 수분부족분(HD)은 우리나라 4.5g/$m^3$, 네덜란드 3.5g/$m^3$로 우리나라의 시설내부가 더 건조하게 관리되었다. 특히 우리나라 야간의 수분부족분은 매우 변화폭이 컸다. 주간 평균 이산화탄소 농도는 우리나라와 네덜란드가 반대의 경향으로 관리되었고 이는 네덜란드의 겨울철 난방 시 배출되는 이산화탄소를 시설내부로 시용한 결과에 기인한다. 일중 외부 광량 대비 시설내부 24시간 평균온도와 주간 이산화탄소 농도는 우리나라는 매우 불균일하게 관리되었지만 네덜란드의 경우 균일하게 관리되었다. 네덜란드의 시설 내.외부 환경은 우리나라에 비해 균일하게 관리되었고, 우리나라의 불균일한 시설내부 환경은 작물의 불균일한 생육을 유도할 것으로 판단된다.

• Advances in Traditional Medicine
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• 제4권3호
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• pp.187-195
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• 2004

A number of plants from different geographical origins have been shown to possess antioxidant activity. Some of them have been developed as natural antioxidant formulations for food, cosmetic and other applications. Bangladeshi flora is a rich source of a range of plant species, many of which are medicinal plants, and have been used in the preparations of the Unani and Ayurvedic traditional medicines. There are no, or just a few, reports on any systematic screening of the extracts of Bangladeshi plants for free radical scavenging activity using DPPH assay available to date. As part of our on-going search for biological activity in Bangladeshi plants, Kadam (Anthocephalus chinensis), Goran (Ceriaps decandra), Swarnalata (Cuscuta reflexa), Gab (Diospyros peregrina), Sundari (Heritiera fomes), Dhundul (Xylocarpus granatum) and Possur (Xylocarpus mekongensis) have been selected for the assessment of their free radical scavenging activity, and studies on the contents of alkaloids, anthraqunones, flavonoids and tannins in these extracts. Most of these species have been used in traditional medicine in Bangladesh and other countries for the treatment of various illnesses ranging from common cold to cancer. All extracts, except the methanol extract of Cuscuta reflexa, displayed significant free radical scavenging activity in the DPPH assay $(RC_{50}$ values within the range of $2.75\;{\times}\;10^{-2}\;to\;4.7\;{\times}\;10^{-3}\;mg/mL)$. Among these extracts, the methanol extract of Xylocarpus granatum exhibited the most potent activity $(4.7\;{\times}\;10^{-3}\;mg/mL)$ and that of Cuscuta reflexa had the least activity $(1.64\;{\times}\;10^{-1}\;mg/mL)$. While none of these plants showed positive tests with Dragendorff's reagent, presence of low to moderate amounts of phenolic compounds, e.g. anthraquinones, flavonoids and tannins was evident in all of these plants, except for the methanolic extracts of C. reflexa and the barks of D. peregrina, which did not display any evidence for the presence of flavonoids and anthraquinones, respectively.

• Asian Pacific Journal of Cancer Prevention
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• 제17권sup3호
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• pp.125-130
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• 2016

Nepeta cataria L. has been used in traditional medicine of some countries. Here the cytotoxic and apoptogenic activity of methanol extracts, n-hexane, dichloromethane, ethyl acetate, n-butanol, and acqueous extracts and the essential oil obtained from the aerial parts of the plant were evaluated with PC3, DU-145 and MCF-7 cell lines. Cell viability, histograms of PI stained fragmented DNA in apoptotic cells and Western blot analysis of proteins involved in the cascade of apoptosis were compared in all samples. Thirty components were identified as volatile, representing 99.7% of essential oil composition after GC-MS analysis of the oil obtained from aerial parts of the N. cataria by hydro-distillation. The major oil components of the essential oil were nepetalactone stereoisomers. Comparing IC50 values showed estrogen receptor positive PC3 cells were more sensitive to the cytotoxic effects of N. cataria in comparison with low hormone-receptor presenting DU-145 cells. Among multiple extracts and essential oils of the plant, only the ethyl acetate extract could significantly decrease cell viability in PC3 cells, in a concentration dependent manner. Ethyl acetate extract of N. cataria treated cells showed a sub-G1 peak in PC3 cells in a concentration dependent manner that indicates the involvement of an apoptotic process in ethyl acetate extract-induced cell death. Western blotting analysis showed that in PC3 cells treated with ethyl acetate (48 h) caspase 3 and PARP were cleaved to active forms. Overall, the results suggest that further analytical elucidation of N. cataria in respect to finding new cytotoxic chemicals with anti-tumor activity is warranted.

• Asian Pacific Journal of Cancer Prevention
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• 제17권4호
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• pp.1857-1859
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• 2016

Background: Hodgkin's lymphoma (formerly, Hodgkins disease) is a potentially curable malignancy with distinctive biological behavior and specific clinical characteristics. Limited information is available from developing countries for patients with classical Hodgkin's lymphoma (cHL). Therefore we reviewed the demographical and clinico-hematological profiles along with bone marrow infiltration patterns in adult patients presenting at Liaquat National Hospital and Medical College. Materials and Methods: In this cross sectional study, 62 adult (${\geq}15years$) patients with cHL were enrolled from January 2010 to December 2014. Results: The mean age was $29.7{\pm}13.8years$ with a median of 30 years. The male to female ratio was 2:1. B symptoms were present in 72.5% of patients and lymph node enlargement in 85.4%. The frequency of bone marrow infiltration in our cHL patients was found to be 27.4%, the pattern being predominantly focal followed by diffuse. The mean hemoglobin was $9.4{\pm}1.9g/dl$ with a mean MCV of $78.1{\pm}7.9fl$, a mean total leukocyte count of $10.9{\pm}20.6{\times}10^9/l$ and a mean platelet count of $241.6{\pm}150.1{\times}10^9/l$. Conclusions: Our analysis shows that clinico-pathological features of cHL in Pakistan are comparable to published data. Peripheral lymphodenopathy associated with B symptoms is the commonest presentation. Bone marrow involvement is more common in our setup as patients usually presented at an advanced stage of disease.

• Nutrition Research and Practice
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• 제7권6호
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• pp.466-474
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• 2013

Despite the reports on safety concerns regarding the relationship between aluminum salts and neurological and bone disease, many countries continue to use aluminum as phosphate binders among patients with renal failure. In search for a diet supplement that could reduce aluminum toxicity related to renal failure, we carried out this prospective animal study in which the fenugreek seeds were assessed for their effects on rats nephrotoxicity induced by aluminum chloride ($AlCl_3$). Oral $AlCl_3$ administration during 5 months (500 mg/kg bw i.g for one month then 1600 ppm via drinking water) led to plasma biochemical changes, an inhibition of alkaline phosphatase (ALP), a decrease of total antioxidant status (TAS), and an induction of lipid peroxidation (LPO) in the blood and brain, in addition to kidney atrophy and morphological alterations at the level of Bowman's capsule, the glomerulus and different sorts of tubules, reminiscent of some known kidney disease. The treatment with the whole fenugreek seed powder (FSP) (5% in the diet) during the last 2 months showed its effectiveness in restoring normal plasma values of urea, creatinine, ALP and glucose, as well as re-increasing the TAS, inhibiting LPO and alleviating histopathological changes in the injured kidneys. This study highlights the induced nephrotoxicicity, as well as the related toxicity in the brain and bone, by chronic oral ingestion of the aluminum salts. However, the maintenance of a diet supplemented with fenugreek seeds could offer protection for the kidney, bone and brain, at the same time.

• 대한화장품학회지
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• 제22권2호
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• pp.41-51
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• 1996

Phaseolus aureus (mung bean), Leguminosae, has been used as an antidote from the ancient time. Especially, it has been widely used for cleaning face and skin in oriental countries. Although several constituents such as fatty acids, phytoallexin and phaseol derivatives were reported in P. aureus and related species including seedlings, there has been a few report to describe its biological activity. Therefore, in this investigation, the ethanol extract from P. aureus was obtained and its biological activities including the antioxidative and anti-inflammatory activities were studied. The 70% ethanol extract from P. aureus showed dose-dependent antioxidative activity (52.3% inhibition at 4 mg/ml) against lipid peroxidation assay, while the extract did not show the inhibitory activity of superoxide radical formation. The extract also showed the topical anti-inflammatory activity against croton-oil and arachidonic acid induced mouse ear edema test (18-19% inhibition at 7.5 mg/ear) as well as mild inhibitory activity against picryl chloride induced delayed hypersensitivity in mouse. For investigating active principles, vitexin and isovitexin (apigenin C-glycoside) as flavonoids, and adenosine were isolated from the extract using silica gel chromatography. The actual contents of vitexin and isovitexin were found to be 3.7 and 2.4 mg/g extract, respectively. Vitexin and isovitexin showed the antioxidative activity. They showed the topical anti-inflammatory activity, although the activities were not potent compared to the reference compounds. These results suggested that vitexin and isovitexin may be, at least in part, the compounds contributing the antioxidative activity in vitro and the topical anti-inflammatory activity of P. aureus in vivo. All results of present study might be one of the scientific rationale in using mung bean for skin care from the ancient time.

• 한국산학기술학회논문지
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• 제10권7호
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• pp.1556-1567
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• 2009

자동차 주요 생산국인 우리나라 보행자의 교통사고 사망률은 인구 10만 명 당 5.28명으로서 OECD 평균의 약 2.5배에 달한다. 보행자를 감지하고 운전자에게 경보를 보내주는 시스템이 개발되어 보행자 교통사고를 조금이라도 줄일 수 있다면, 그 자체만으로도 보행자 감지 시스템의 가치는 충분하기 때문에 PDS에 대한 관심이 높아지고 있다. 보행자 교통사고율은 야간에 더 높기 때문에, 야간 보행자 감지 시스템에 주요 자동차 회사들이 관심을 두고 있으나, 그들은 일반적으로 고가의 나이트비젼 또는 복합적 센서를 사용하는 장비를 채택하고 있다. 본 논문에서는 PDS에서 나이트비젼 대신에, 넓은 동적 범위를 갖는 가시 스펙트럼 대역 흑백 카메라 한 대만을 사용하는 야간 보행자 감지 기법을 제안한다. 서로 다른 환경에서 촬영된 야간 동영상들에 대해 실험한 결과, 제안 알고리듬이 에지가 어느 정도 정확하게 검출되는 상황이라면 정확한 보행자 검출 성능을 보였다.

• International Journal of Knowledge Content Development & Technology
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• 제10권4호
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• pp.29-46
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• 2020

The paper describes the quantitative and qualitative dimensions of artificial neural networks (ANN) in India in the global context. The study is based on research publications data (8260) as covered in the Scopus database during 1999-2018. ANN research in India registered 24.52% growth, averaged 11.95 citations per paper, and contributed 9.77% share to the global ANN research. ANN research is skewed as the top 10 countries account for 75.15% of global output. India ranks as the third most productive country in the world. The distribution of research by type of ANN networks reveals that Feed Forward Neural Network type accounted for the highest share (10.18% share), followed by Adaptive Weight Neural Network (5.38% share), Feed Backward Neural Network (2.54% share), etc. ANN research applications across subjects were the largest in medical science and environmental science (11.82% and 10.84% share respectively), followed by materials science, energy, chemical engineering and water resources (from 6.36% to 9.12%), etc. The Indian Institute of Technology, Kharagpur and the Indian Institute of Technology, Roorkee lead the country as the most productive organizations (with 289 and 264 papers). Besides, the Indian Institute of Technology, Kanpur (33.04 and 2.76) and Indian Institute of Technology, Madras (24.26 and 2.03) lead the country as the most impactful organizations in terms of citation per paper and relative citation index. P. Samui and T.N. Singh have been the most productive authors and G.P.S.Raghava (86.21 and 7.21) and K.P. Sudheer (84.88 and 7.1) have been the most impactful authors. Neurocomputing, International Journal of Applied Engineering Research and Applied Soft Computing topped the list of most productive journals.

• 한국응용곤충학회지
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• 제62권2호
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• pp.83-87
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• 2023

애긴노린재는 긴노린재과에 속하며 한국을 포함한 동아시아 국가의 다양한 곡물 및 관상용 식물의 주요 해충으로 여겨진다. 본 연구에서는 애긴노린재의 17,367 bp 미토콘드리아 유전체에서 13개의 protein-coding genes, 22개의 transfer RNA genes, 2개의 ribosomal RNA genes과 non-coding A+T rich region를 확인하였다. G+C content는 23%로 나타났고 다른 긴노린재과와의 염기서열 유사성이 N. cymoides (94.5%), N. fuscovittatus (91.7%)으로 높은 것을 발견하였다. 애긴노린재의 미토콘드리아 유전체 정보는 향후 긴노린재과의 진화 연구와 해충 방제를 위한 정보로 널리 사용될 수 있다.