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Synthesis of UV-Curable PDMS-Modified Urethane Acrylate Oligomer and Physical Properties of the Cured Film (광경화형 PDMS 변성 우레탄 아크릴레이트 올리고머 합성과 경화필름 물성에 관한 연구)

  • Yeo, Jun-Seok;Hwang, Seok-Ho
    • Elastomers and Composites
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    • v.48 no.4
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    • pp.249-255
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    • 2013
  • Hydroxypropyl terminated PDMS was synthesized by the hydrosilylation reaction with allyl alcohol in the presence of Karstedt's catalyst. And them, an one-pot reaction with HDI isocyanurate trimer and hydroxyethyl methacrylate was conducted to give a silicone-modified urethane acrylate oligomer (PUA oligomer) having 9000 g/mol, weight average molecular weight. The synthesized PUA oligomer was characterized by using FT-IR and GPC. The UV-curable coatings were prepared by PUA oligomer blending with a reactive monomer (phenylthioethyl acrylate) under the different mole ratios. It was found that the refractive index of cured film increased when the reactive monomer was added but there was no relationship between the refractive index and amount of reactive monomer. Also, their transmittance for cured films was not change as increasing the content of reactive monomer.

Effect of Oviposition Time on Egg Qualities in Laying Hen (산란계에 있어서 방란시간이 란질에 미치는 영향)

  • 이춘지;정선부;오세정
    • Korean Journal of Poultry Science
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    • v.14 no.2
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    • pp.113-123
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    • 1987
  • This study was carried out to investigate the effects of age of hen and oviposition time on egg weight, egg shell quality and e88 shape index in White Leghorn laying hens. The data were collected from 150 laying hens for about 4 months from September 1, 1986 to January 6, 1987. The results obtained from this study were summarized as follows; The percentage of the eggs produced before noon was decreased and that of the eggs produced after noon was increased as the hen gets older. Egg weight was increased rapidly to 270 days of age but after 270 days of age the rate of egg weight increase was slowly downed. The egg shell thickness became thinner and egg shell breaking strength was reduced and egg shape index was increased as the hen gets older. The egg weight was decreased as the oviposition time was proceeded and the regression coefficients of egg weight on oviposition time were -0.6788--0.4170, which means that the egg weight was decreased 0.4170-0.6788g per one hour delay of oviposition time. Egg shell thickness was increased 0. 0.00377-0.00643mm and egg shell breaking strength improved 0.0287-0.034kg/$\textrm{cm}^2$ per one hour delay of oviposition time. But it seems that there was no relationship between the oviposition time and the egg shape index.

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Effects of Cynanchum wilfordii Extract on Serum Lipid Components and Enzyme Activities in Hyperlipidemic and Streptozotocin-Induced Diabetic Rats (백하수오 추출액이 고지혈증 및 Streptozotocin 유발 당뇨성 흰쥐의 혈청 지질성분 및 효소활성에 미치는 영향)

  • 김한수
    • Korean Journal of Human Ecology
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    • v.7 no.2
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    • pp.1-11
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    • 2004
  • The purpose of this study was designed to observe the effects of the feeding Cynanchum wilfordii extract on the improvement of the blood glucose, lipid components in the serum of dietary hyperlipidemic and streptozotocin(STZ) -induced diabetic rats(S.D. strain, ♂) fed the experimental diets for 5 weeks. Concentrations of total cholesterol, atherosclerotic index, LDL, LDL-Cholesterol, free-cholesterol. cholesteryl ester, TG, PL and blood glucose in serum were significantly higher in the cholesterol administration groups((group 2(cholesterol+water), 4(cholesterol+Cynanchum WIlfordii 3.5g% extract)) than those in the control group (group1 , basal diet+water). But the concentrations of total cholesterol. atherosclerotic index, LDL, LDL- cholesterol. free-cholesterol, cholesteryl ester, TG, PL and blood glucose in serum were remakably lower in the group 4 than those in the group 2. In the STZ(55mg/kg B.W.)-induced diabetic groups((group 3(STZ, IP.)+water), 5(STZ(IP.)+Cynanchum WIlfordii 3.5g% extract? the serum total cholesterol, atherosclerotic index, LDL, LDL-cholesterol, free-cholesterol. cholesteryl ester, TG, PL and blood glucose concentrations actions were rather lower in the group 5 than those in the group 3. In the ratio of HDL -cholesterol concentration to total cholesterol and HDL-cholesterol concentration, Cynanchum wilfordii extract administration groups were higher percentage than III the groups 2 and 3. The activities of aspartate aminotransferase(AST), alanine aminotransferase(ALT), alkaline phosphatase (ALP) and lactate dehydrogenase(LDH) in serum were rather lower in the Cynanchum wllfordii extract administration groups (group 4,5) than in the cholesterol diet group(group 2) and STZ-induced diabetic group (group 3). From the above research, the physiological activity substances in Cynanchum wllfordii were effective on the improvement of the blood glucose, lipid compositions in serum of dietary hyperlipidemic and STZ-induced diabetic rats. And particularly, physiological activity substance in Cynanchum wilfordii was more effective therapeutic regimen for the control of metabolic derangements in adult disease.

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The Iron Status and Diet Quality of Pregnant Women during the First Five Months of Pregnancy (임신 전반기 여성의 철분 영양상태와 식사의 질)

  • 윤지숙;박정아;손숙미
    • Korean Journal of Community Nutrition
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    • v.8 no.6
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    • pp.803-813
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    • 2003
  • Literature suggests that iron deficiency anemia is prevalent among pregnant women all over the world. This study was designed to evaluate the iron status of pregnant women during the fist five months, with the intention of determining ways to reduce the prevalence of iron deficiency anemia among pregnant women in Korea. We collected dietary information and measured the biochemical status of iron in 171 pregnant women over 16 weeks of gestation (=16.7$\pm$2.34 week). Dietary intakes for 3 days were collected using the 24 hour recall and food record methods. The daily Fe intake was measured using the food frequency method. The Body Mass Index (BMI), calculated by using the pre-pregnancy weight and height, indicated that 31.3% of subjects were under-weight. We divided the subjects into normal and anemic group by using the serum ferritin levels. It appeared that the mean dietary intake of iron was 52.3% of the recommended level for pregnant women. The dietary quality evaluation showed that pregnant women ate only 58% of the recommended amount in the food groups of meat, fish, eggs, beans and milk and dairy products. The hematological indices showed that the mean Hemoglobin (Hb) was 11.9 g/dl, Hematocrit (Hct) was 35.1%, ferritin was 23.9 $ng/ml$, and transferrin was 297.3 ${\mu}g/dl$. The dietary intake of iron was significantly lower and the vitamin C intake was significantly higher in the anemic group. The pre-pregnancy BMI was significantly lower in the anemic group. Variables affecting iron intake were the Fe intake frequency index and the food group score. The Fe index showed significantly positive correlation with the pre-pregnancy food intake and the food group score. Hb showed a significantly positive correlation with the pre-pregnancy food intake. We concluded that strategies to improve iron status be implemented in the pre-pregnant stage so as to reduce the prevalence of iron deficiency and that we should stress on the importance of an adequate diet as well as the maintenance of a heathy weight.

Analysis of Bone Mineral Density, Biochemical Index and Nutrient Intakes of 30-70 Years Old Women -Based on 2011 KNHANES- (30~70대 여성의 골밀도, 생화학적 특성 및 영양소 섭취 분석 -2011년 국민건강영양조사를 중심으로-)

  • Koo, Jae Ok;Kim, Myung Sook
    • Korean Journal of Community Nutrition
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    • v.19 no.4
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    • pp.328-341
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    • 2014
  • Objectives: This study was carried out to investigate bone mineral density (BMD), blood pressure, age and biochemical index and nutrient intakes, and to analyze the relationship between BMD, blood pressure, biochemical index, nutrient intakes of Korean women. Methods: The study subjects were 499 women with a age range of 30-79 years living in Seoul and Kyunggi area who participated in 2011 KNHANES. The study subjects were divided into 5 age groups : 30 years (145), 40 years (110), 50 years (102), 60 years (85) and 70 years (57), and 3 BMD groups: normal 258 (50.4%), osteopenia 163 (32.9%) and osteoporosis 78 (16.7%). Results: The average waist circumference, BMI and body fat increased with age, but fat free mass decreased with age. Average BMD and T-score was decreased from 0.84, $0.74g/cm^2$ in 30 years to 0.05, $-1.05g/cm^2$ in 70 years. The rates of osteopenia and osteoporosis increased significantly 22% in 30~40 years, 47% in 50 years and 56% in 60~70 years. Systolic blood pressure and cholesterol were significantly increased with age. The rates of hypertension was significantly increased 2.1% in 30 years, 30.4% in 50 years 89.5% in 70 years. Average nutrient intakes such as protein, calcium, iron, vitamin A and C were significantly decreased with age. There were significant negative correlations between age and calcium, systolic blood pressure, triglyceride. Conclusions: In this study, we found the risk of osteoporosis and hypertension were significantly increase with over 50 years age. Calcium and protein intake decreased with age. Therefore, in order to prevent osteoporosis and hypertension, adult women need to be educated regarding the importance of protein, calcium and other nutrients in their diet.

A Study on the Relation between Dynamic Deflection Modulus and In-Situ CBR Using a Portable FWD (소형FWD를 이용한 노상토의 동적변형계수와 현장 CBR의 상관 연구)

  • Kang, Hee Bog;Kim, Kyo Jun;Park, Sung Kyoon;Kim, Jong Ryeol
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.12 no.2
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    • pp.149-155
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    • 2008
  • The road construction, as part of effort to ease the worsening traffic, has been underway throughout the nation, while the existing road has been increasingly losing its load carrying capacity due to such factors as heavy traffic and weathering. In the case of site, the soil type, plasticity index, and specific gravity were SC, 12.2%, and 2.66, respectively. The maximum dry density, optimum moisture content and modified CBR were $1.895g/cm^3$ (Modified Compaction D), 13.6%, and 16.2%, respectively. A correlation of coefficient expressed good interrelationship by 0.90 between the CBR estimated from a dynamic penetration index of dynamic cone penetrometer test and a deformation modulus converted from a dynamic deflection modulus obtained from a portable FWD test.

Studies of the effects and mechanisms of ginsenoside Re and Rk3 on myelosuppression induced by cyclophosphamide

  • Han, Jiahong;Xia, Jing;Zhang, Lianxue;Cai, Enbo;Zhao, Yan;Fei, Xuan;Jia, Xiaohuan;Yang, He;Liu, Shuangli
    • Journal of Ginseng Research
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    • v.43 no.4
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    • pp.618-624
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    • 2019
  • Background: Ginsenoside Re (Re) is one of the major components of Panax ginseng Meyer. Ginsenoside $Rk_3$ ($Rk_3$) is a secondary metabolite of Re. The aim of this study was to investigate and compare the effects and underlying mechanisms of Re and $Rk_3$ on cyclophosphamide-induced myelosuppression. Methods: The mice myelosuppression model was established by intraperitoneal (i.p.) injection of cyclophosphamide. Peripheral blood cells, bone marrow nucleated cells, and colony yield of hematopoietic progenitor cells in vitro were counted. The levels of erythropoietin, thrombopoietin, and granulocyte macrophage colony-stimulating factor in plasma were measured by enzyme-linked immunosorbent assay. Bone marrow cell cycle was performed by flow cytometry. The expression of apoptotic protein bcl-2, bax, and caspase-3 was detected by Western blotting. Results: Both Re and $Rk_3$ could improve peripheral blood cells, bone marrow nucleated cell counts, thymus index, and spleen index. Furthermore, they could enhance the yield of colonies cultured in vitro and make the levels of granulocyte macrophage colony-stimulating factor, erythropoietin, and thrombopoietin normal, reduce the ratio of $G_0/G_1$ phase cells, and increase the proliferation index. Finally, Re and $Rk_3$ could upregulate the expression of bcl-2, whereas they could downregulate the expression of bax and caspase-3. Conclusion: Re and $Rk_3$ could improve the hematopoietic function of myelosuppressed mice. The effect of $Rk_3$ was superior to that of Re at any dose. Regulating the levels of cytokines, promoting cells enter the normal cell cycle, regulating the balance of bcl-2/bax, and inhibiting the expression of caspase-3 may be the effects of Re and $Rk_3$ on myelosuppression.

The Crucial Role of the Establishment of Computed Tomography Density Conversion Tables for Treating Brain or Head/Neck Tumors

  • Yang, Shu-Chin;Lo, Su-Hua;Shie, Li-Tsuen;Lee, Sung-Wei;Ho, Sheng-Yow
    • Progress in Medical Physics
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    • v.32 no.3
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    • pp.59-69
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    • 2021
  • Purpose: The relationship between computed tomography (CT) number and electron density (ED) has been investigated in previous studies. However, the role of these measures for guiding cancer treatment remains unclear. Methods: The CT number was plotted against ED for different imaging protocols. The CT number was imported into ED tables for the Pinnacle treatment planning system (TPS) and was used to determine the effect on dose calculations. Conversion tables for radiation dose calculations were generated and subsequently monitored using a dosimeter to determine the effect of different CT scanning protocols and treatment sites. These tables were used to retrospectively recalculate the radiation therapy plans for 41 patients after an incorrect scanning protocol was inadvertently used. The gamma index was further used to assess the dose distribution, percentage dose difference (DD), and distance-to-agreement (DTA). Results: For densities <1.1 g/cm3, the standard deviation of the CT number was ±0.6% and the greatest variation was noted for brain protocol conditions. For densities >1.1 g/cm3, the standard deviation of the CT number was ±21.2% and the greatest variation occurred for the tube voltage and head and neck (H&N) protocol conditions. These findings suggest that the factors most affecting the CT number are the tube voltage and treatment site (brain and H&N). Gamma index analyses for the 41 retrospective clinical cases, as well as brain metastases and H&N tumors, showed gamma passing rates >90% and <90% for the passing criterion of 2%/2 and 1%/1 mm, respectively. Conclusions: The CT protocol should be carefully decided for TPS. The correct protocol should be used for the corresponding TPS based on the treatment site because this especially affects the dose distribution for brain metastases and H&N tumor recognition. Such steps could help reduce systematic errors.

Selecting the optimal threshold based on impurity index in imbalanced classification (불균형 자료에서 불순도 지수를 활용한 분류 임계값 선택)

  • Jang, Shuin;Yeo, In-Kwon
    • The Korean Journal of Applied Statistics
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    • v.34 no.5
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    • pp.711-721
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    • 2021
  • In this paper, we propose the method of adjusting thresholds using impurity indices in classification analysis on imbalanced data. Suppose the minority category is Positive and the majority category is Negative for the imbalanced binomial data. When categories are determined based on the commonly used 0.5 basis, the specificity tends to be high in unbalanced data while the sensitivity is relatively low. Increasing sensitivity is important when proper classification of objects in minority categories is relatively important. We explore how to increase sensitivity through adjusting thresholds. Existing studies have adjusted thresholds based on measures such as G-Mean and F1-score, but in this paper, we propose a method to select optimal thresholds using the chi-square statistic of CHAID, the Gini index of CART, and the entropy of C4.5. We also introduce how to get a possible unique value when multiple optimal thresholds are obtained. Empirical analysis shows what improvements have been made compared to the results based on 0.5 through classification performance metrics.

Interrater Reliability of Upper Extremity Function Assessment on Stroke (뇌졸중 환자에 대한 상지기능 평가도구의 검사자간 신뢰도)

  • Hwang, Seong-Soo;Kim, Pu-Reum;Won, Ji-In;Yoo, Seon-Ju;Yoon, Jun-Byung;Lee, Keun-Woo;Lee, Wang-Jae
    • PNF and Movement
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    • v.10 no.1
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    • pp.1-7
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    • 2012
  • Purpose : To verify the interrater reliability of upper extremity function assessment among three tools(Wolf motor function test, Motor assessment scale, Fugl-meyer assessment scale). Methods : The subjects of this study 40 (20 was physical therapists and 20 was physical therapy students). For the test one patients with chronic hemiparesis after stroke participated in the study. The Wolf Motor Function Test consists of 16 functional tasks. The motor assessment scale consists of 3 functional tasks. The fugl-meyer assessment scale consists of 8 functional tasks. All test sessions were videotaped and scored by 40 subjects. Analysis : The data was analysis by SPSS PC 14.0 with Cronbach alpha Coefficients, intraclass Correlation Coefficients Kendall tau-b value. Results : WMFT was highly scored in Cronbach's value, Cronbach's ${\alpha}=0.819$ that means high interrater reliability among assessment. WMFT was highly scored all items in p-value except one item, that means high p-value between therapists and students. WMFT was highly scored in Intrarater correlation coefficient (ICC) = 0.79, that means high interrater reliability of each examination item. WMFT was low index of coincidence from all items, MAS was low index of coincidence from a tim and FMA was low index of coincidence from 4 items. Conclusion : The interrater reliability of WMFT were compared with MAS, FMA and highly verified. WMFT can be more useful tool among upper extremity function assessment.