• 제목/요약/키워드: G-Index

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각종 갑상선 질환에서 혈청 Thyroxine 결합글로부린 (TBG)의 진단적 의의 (Diagnostic Significance of the Serum Thyroxine Binding Globulin(TBG) in Various Thyroid Diseases)

  • 한봉헌;이헌영;고석만;윤상룡;노흥규
    • 대한핵의학회지
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    • 제15권2호
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    • pp.43-51
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    • 1981
  • In an attempt to evaluate the diagnostic significance of the serum thyroxine binding globulin (TBG) in various thyroid disease states, the authors measured serum $T_3$ uptake, $T_3$, total $T_4\;free\;T_4$, TSH and TBG by radioimmunoassay technique, and calculated the free $T_4$ index$(FT_4I)$ and $T_4/TBG$ ratio in 10 cases of normal subjects, 11 cases of hypothyroidism, 62 cases of euthyroidism and 37 cases of hyperthyroidism. The data were analysed in the aspects of diagnostic significance in each thyroid disease state, and the results were as follows; 1. In 10 cases of normal subjects, serum TBG was $17.4\sim26.8{\mu}g/ml$, $FT_4I$ was $5.1\sim9.7$, and $T_4/TBG$ ratio was $21.9\sim49.9(Mean{\pm}S.D.)$. 2. In 62 cases of euthyroidism with diffuse and nodular goiter, $FT_4I$ was $7.26{\pm}1.82,\;T_4/TBG$ ratio was $31.47{\pm}10.42$, and there were no significant difference from those of normal subjects (p>0.5). 3. In 11 cases of hypothyroidism, the $FT_4I$ was $3.13{\pm}2.15,\;T_4/TBG$ ratio was $11.3{\pm}5.31$, significantly lower than normal controls (p<0.01). 4. In 37 cases of hyperthyroidism, the $FT_4I$ was $30.0{\pm}12.0,\;T_4/TBG$ ratio was $121.4{\pm}62.2$, significantly higher than normal controls (p<0.01). 5. There were significant correlations between the $FT_4I$ and $T_4/TBG$ ratio, total $T_4\;and\;T_4/TBG$ ratio, in each thyroid function states. 6. The $FT_4I$ showed 100% of diagnostic value in hyperthyroidism, 89.2% in euthyroidism, and 80% in hypothyroidism group. The $T_4/TBG$ ratio showed 100% of diagnostic value in hyperthyroidism and hypothyroidism, and 80.6% in euthyroidism group. The above results suggest that $T_4/TBG$ ratio and $FT_4I$ showed same diagnostic value in hyperthyroidism group, but $T_4/TBG$ showed higher diagnostic significance than $FT_4I$ in hypothyroidism.

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최장발성폐기능저하를 동반한 일측성 성대마비 환자에서의 S/Z Ratio와 최장 발성시간(Maximum Phonation Time)의 유용성 비교 (Usefulness of S/Z Ratio and Maximum Phonation Time in Unilateral Vocal Fold Paralysis with Decreased Pulmonary Function)

  • 박준표;정고은;강병철;김성태;남순열;김상윤;노종렬;최승호
    • 대한후두음성언어의학회지
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    • 제23권2호
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    • pp.129-132
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    • 2012
  • Background and Objectives : MPT is directly related to degree of glottal closure. So it is widely used in the assessment of glottal closure with unilateral vocal fold paralysis. But MPT could be influenced not only by glottal closure but also by pulmonary function. So MPT might not reflect glottal closure in UVFP with decreased pulmonary function. The purpose of the study is to evaluate usefulness of MPT and ratio of /s/ time to /z/ time before and after injection laryngoplasty in UVCP with decreased pulmonary function. Materials and Methods : This study involved 34 patients with unilateral vocal fold paralysis : with decreased pulmonary function in group A (n=15) : with normal pulmonary function in group B (n=19). All patients underwent injection laryngoplasty. Paramters of perceptual analysis, acoustic analysis, aerodynamic analysis, videostroboscopy were compared between two groups. Results : Breathness and asthenic scale, G scale of perceptual analysis were significantly improved in both groups. Glottal gap index were significantly decreased after injection in both groups. In aerodynamic analysis, MPT was improved after injection laryngoplasty in both groups, but S/Z ratio was improved only in group B. In correlation analysis, /s/ time was not correlated with pulmonary function. Conclusion : S/Z ratio reflects neither the pulmonary function nor the glottal clousure properly. MPT is more useful indicator than S/Z ratio to evaluate vocal fold paralysis even with decreased pulmonary function.

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Impact of Marketing Losses on Efficiency in Transacting Banana in Scarce Rainfall Zone of Andhra Pradesh, India

  • Kumar, K. Nirmal Ravi
    • Agribusiness and Information Management
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    • 제9권2호
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    • pp.1-11
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    • 2017
  • Introduction: To analyze the impact of marketing losses on efficiency in transacting banana in Kurnool district of SRZ in Andhra Pradesh and to assess the opinions of the farmers on the constraints in transacting banana. Research back ground, Materials and Methods: The study relies exclusively on primary information obtained from the banana farmers of Kurnool District. Purposive sampling procedure was followed for the selection of the study area. Top two mandals in the district and top two villages in each mandal are selected in accordance with the area under cultivation of banana. Probability proportion to size was followed regarding the selection of sample farmers and accordingly 60 marginal, 37 small and 23 other farmers were selected and thereby, the total sample size was 120. Result and Discussion: Three marketing channels were identified in the marketing of banana in Kurnool district viz., Producer ${\rightarrow}$ Local-exporter ${\rightarrow}$ Wholesaler ${\rightarrow}$ Retailer ${\rightarrow}$ Consumer (Channel-I), Producer ${\rightarrow}$ Wholesaler ${\rightarrow}$ Cart-vendor ${\rightarrow}$ Consumer (Channel-II) and Producer ${\rightarrow}$ Juice-holder ${\rightarrow}$ Consumer (Channel-III). With the inclusion of marketing losses in the price spread analysis of banana in all the three channels, the marketing costs of all the intermediaries were increased and thereby, the farmer's share in consumer's rupee and Net Marketing Margins of the agencies are on the decline. So, without inclusion of marketing losses, the farmer's share in consumer's rupee and Net Marketing Margins of all the agencies are overvalued. The higher the marketing losses, the more is the negative impact on farmer's net selling price, net marketing margins of the intermediaries and marketing efficiency. The sample farmers are facing major problems in marketing of banana like frequent price fluctuations, unorganized marketing and lack of transportation facilities on priority basis. Suggestions: It is suggested to educate the farmers regarding the optimum maturity index for harvest, use of mechanical harvesters, proper placement of fruits during storage and ripening, better packaging and cushioning technologies to absorb shocks during transportation, strengthening of storage facilities and transport facilities, encourage co-operative marketing etc., to promote marketing efficiency of banana in the study area.

벼 건답휴립직파재배(乾畓畦立直播栽培)에서 효과적(效果的)인 제초제(除草劑) 사용법(使用法) (Effective Herbicide Application on Dry Seeded Paddy Rice)

  • 이석순;김순철
    • 한국잡초학회지
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    • 제11권1호
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    • pp.3-10
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    • 1991
  • 벼 간답직파에 효과적인 제초방법을 구명하기 위하여 이앙재배를 하여온 논에 시판중인 수도용 제초제를 초기 (파종후 1 일), 중기 (파종 18 일), 후가 (파종 40 일)의 3개 시기에 처리하여 제초제의 약해, 제초효과, 벼 생육 및 수량에 미치는 영향을 조사한 결과는 다음과 같다. 1. 건답직파재배를 하므로서 밭상태인 초기 30 일간은 피, 바랭이, 드렁새, 강아지풀, 적미(赤米), 냉이류 등과 같이 밭잡초가 발생하였으나 상시담수 이후에는 밭잡초의 생육은 억제되었고, 대신 자귀풀, 올방개, 너도방동산이, 여뀌바늘, 사마귀풀과 같은 논잡초의 발생이 증가되었다. 2. 공시한 제초제 어느것도 벼 입묘수(立苗數)에는 영향을 미치지 않았으나 잡초방제 효과는 현저한 차이를 보였다. 초기 밭상태 30 일간 제초효과가 좋고 벼의 약해가 거의 없었던 것은 thiobencarb, pyrazoate/butachlor 및 chlomethoxyfen/butachlor의 파종직후 처리와 propanil + butachlor의 파종 18일후 처리이었다. 그러나 벼 출수기의 제초효과 가 우수하였던 bentazone/quinchlorac의 파종후 40일 처리구만 손제초의 90% 이상 제초효과를 보였을 뿐 나머지는 제초효과가 매우 낮았다. 3. 출수기의 잡초발생은 간장, 수수, 천립중, 등 숙비율, 수량을 크게 감소시켰고, 생육초기부터 잡초와 경합이 심했던 무제초구에서 이들 형질의 감소정도는 각각 7, 82, 19, 55, 87%로서 수수와 수량이 가장 많이 감소하였다. 4. 파종후 30일의 잡초발생량은 벼 수량과 관계가 없었으나 벼 출수기의 잡초발생량과 벼 수량과는 부의 상관이 있었으며, 벼 수량이 50% 감소되는 잡초 건물중은 $m^2$ 당 600-700g이었다. 5. 출수기의 잡초발생량이 많을수록 벼 상위 3 빛 4위 절간의 도복지수가 직선적으로 증가하였다.

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오소리 지질이 인슐린 비의존형 당뇨환자의 건강상태 당뇨지표 및 혈청지질농도에 미치는 영향 (The Influences of Meles meles Oil on Health Status, Diabetic Index and Serum Lipid Profile in Non - Insulin Dependent Diabetes Mellitus Patients)

  • 박성혜;백승화;한종현
    • 한국식품영양과학회지
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    • 제33권7호
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    • pp.1139-1146
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    • 2004
  • 본 연구자들은 다른 동물성 지질에 비해 콜레스테롤 함량이 낮고 불포화지방산 함량이 높은 오소리 지질을 당뇨환자들에게 섭취시킨 후 혈당, 혈청의 당뇨지표 및 혈청 지질의 변화를 관찰하여 당뇨환자들에게 동물성인 오소리 지질 섭취가 혈당유지 및 합병증 관리 에 합당한가를 평가하여 오소리 지질을 기능성 식품의 원료로 활용할 수 있는가를 확인하고자 하였다. 일일 평균 7.26 g의 오소리 지질을 12주간 섭취한 후에 총 지질의 섭취량은 유의적 인 차이가 없었으나 $\omega$3계 지방산과 다가불포화지방산의 섭취량은 유의적으로 증가하였고 콜레스테롤의 섭취량은 유의적으로 감소된 결과를 나타냈다. 공복 시 혈당이 오소리 지질의 섭취에 따라 유의적인 상승을 나타내지 않았고 fructosamine과 glucagon농도는 오소리 지질의 섭취 6주째부터 유의적으로 상승되었다. 혈청의 LDL-콜레스테롤 및 중성지방의 농도는 오소리 지질 섭취에 따라 유의적으로 감소되었고 HDL-콜레스테롤 농도는 유의적으로 상승되었다. 또한 일반적인 건강상태 판정지표로 살펴볼 때 간기능 및 철분 영양상태가 증진되었다. 위의 결과들로 보아 제2형 당뇨환자의 12주간 오소리 지질의 섭취는 건강상태와 혈청지질 profile에는 유익한 영향을 주었고 따라서 동물성인 오소리 지질을 건강보조식품으로 사용하거나 기능성 식품의 원재료로 활용이 가능할 것으로 판단된다. 앞으로 오소리 지질 섭취 수준을 달리한 dose-response 실험을 통해 섭취 수준과 혈청지질 및 지방산 조성의 변화를 관찰하여 오소리 지질의 광범위한 활용을 위한 체계적인 자료를 더 확보하고자 한다.

Diet intervention to improve cardiovascular risk factors among Iranian postmenopausal women

  • Abedi, Parvin;Lee, Mary Huang-Soo;Kandiah, Mirnalini;Yassin, Zaitun;Shojaeezade, Davood;Hosseini, Mostafa;MSc, Reza Malihi
    • Nutrition Research and Practice
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    • 제4권6호
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    • pp.522-527
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    • 2010
  • Cardiovascular disease is a leading cause of death and disability and remains so in the future. The aim of this study was to detect the impact of a 6-month diet intervention on cardiovascular risk factors in postmenopausal Iranian women. It was a randomized controlled trial that carried out in the East Health Clinic in Ahvaz-Iran. This study started on June 2007 and was completed on May 2008. A total 64 healthy postmenopausal women recruited and randomly assigned to the intervention group (35) and control (29). Over the six months follow-up, the intervention group received five educational sessions (two face to face and three lecture discussion classes with slide demonstration) at the first month. These sessions were about menopause, cardiovascular disease and healthy diet. Every participant in the intervention group received one face to face education session at the $3^{rd}$ month, and also received a telephone call at the end of each month starting with the second month to remain on the diet. Pre-intervention and post-intervention anthropometric measurements, blood pressure, blood lipids and dietary intake were assessed. Data analyzed using the SPSS version 15. Descriptive (means and SD), univariate (paired-t test, Chi-Square and Independent T-test) and multivariate (GLM Repeated Measure) statistics were used. Participants in the diet group had significantly lower weight (-0.9 kg), body mass index (-0.4 $kg/m^2$), and fasting blood sugar (-4.5 mg/dl). The diet group significantly increased their daily intake of fiber (+2.3 g, P=0.05), decreased their intake of sodium (-28 mg, P=0.04), and consumption of fruit and vegetable ${\geq}$ 5 serving a day (80%, P=0.03) compared to the control group. Post menopausal women are at a greater risk for cardiovascular disease. Healthy diet using educational intervention can be an effective means of reducing cardiovascular risk in postmenopausal women.

Effects of a Stair-step Growth Pattern on Improvements in Meat Quality and Growth in Hanwoo Steers

  • Li, Z.H.;Lee, H.G.;Xu, C.X.;Hong, Z.S.;Jin, Y.C.;Yin, J.L.;Zhang, Q.K.;Piao, D.C.;Yang, U.M.;Choi, Y.J.
    • Asian-Australasian Journal of Animal Sciences
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    • 제23권11호
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    • pp.1427-1435
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    • 2010
  • The present study was conducted to examine the effect of a stair-stepped feed intake pattern on growth, feed efficiency, and meat quality of Hanwoo steers. Twenty-seven 11-month-old Hanwoo steers were randomly divided into three groups. The control group was fed according to the Korean steer feeding program, and the other two groups were fed according to an alternated feeding schedule of 3-2-4-2 months. During the first three months of the experiment, treatment group 1 (T1) and treatment group 2 (T2) were fed 20% and 30% less than the control group, respectively. For the following two months, the T1 group was fed 20% more than the control group while the T2 group was fed 20% less than the control group. In the third step, T1 and T2 groups were fed 20% and 10% less, respectively, than the control group for four months. In the last two months, T1 and T2 groups were fed 20% more than the control group. After the stair-step feeding trial, steers were fed concentrated feed ad libitum for five months. The altered feed intake pattern did not affect daily body weight gain. However, daily feed intake tended to decrease and growth efficiency tended to increase in the two treatment groups compared to the control group. Altered feed intake also affected blood metabolite levels. The serum glucose and BUN level of the T1 group increased in the first re-fed period compared to the T2 and control groups. The serum cholesterol level of the T2 group decreased in the first restricted-re-fed growth period compared to the T1 and control groups. The serum NEFA levels of the two treatment groups increased from the first restricted period compared to the controls. The serum insulin level of the T2 group increased in the last period compared to the T1 and control groups. Regarding meat yield index, the control group was significantly higher than the T2 group (p<0.05). Regarding meat yield grade, the carcass back fat thickness of the T2 group was significantly higher than the control group (p<0.05). In marbling score, the T1 group was the highest (4.9), followed by the control group (4.1) and the T2 group (4.0). These results indicate that using a stair-stepped growth pattern (T1) can contribute to improvements in growth efficiency and muscle marbling.

미숙아 어머니와 정상아 어머니가 지각한 영아의 기질과 양육스트레스 (A Comparative Study on Infant's Temperament & Parenting Stress by Premature & Full-term Infant's Mother)

  • 김소영;권미경
    • 부모자녀건강학회지
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    • 제8권2호
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    • pp.123-136
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    • 2005
  • This research is to compare the infant's temperament and parenting stress perceived by premature infants' mother and full-term infants' mother. It aims at establishing the healthy relationship between mothers and infants. It investigates the basic data of nursing intervention program to help the mother of premature infant. The period of data collection was from May 1, 2005 to May 30, 2005, and the subjects were total 123 mothers: 44 mothers of premature infants and 79 mothers of full-term infants under 6 months who visited general hospitals, individual pediatrics, and health center located in G city. "What My Baby Is Like(WBL)" developed by Pridham, Chang, and Chiu(1994) and translated by Bang Kyeong Sook(1999) was used as a measuring instrument of infants' temperament, and Parenting Stress Index (PSI) developed by Abidin(1990) and revised and complemented by Kim Dong Hee(1997) was used as a measuring instrument of parenting stress. Collected Data were analyzed through $X^2$-test, t-test, Pearson's correlation with SPSS 12.0 window program. The results are as follows: 1. There was a significant difference in the infant's temperament perceived by premature infants' mothers and full-term infants' mothers (t=-4.08, p=.00). In subcategory, there were significant difference between premature infants' mother and full-term infants' mother in geniality(t=-3.62, p=.00), adaptation(t=-3.43, p=.00) and reaction(t=-2.01, p=.05). 2. There was a significant difference in parenting stress between premature infants' mother and full-term infants' mother(t=6.57, p=.00). The parenting stress of premature infants mothers appeared to be higher than full-term infants' mothers. They showed the higher stress in the mother-child relationship area(t=6.27, p=.00) and child area(t=7.38, p=.00) among 3 areas of parenting stress. 3. There were negative correlation between infants' temperament and parenting stress. As mothers perceived the infant's temperament negatively, the parenting stress. Especially, the negative correlation of infants' temperament and parenting stress of premature infants' mothers(r=-.44) was stronger than that of full-term infants' mothers(r=-37). From the research, as mothers of premature infants receive more stress, their stress can cause the serious problem to the relationship of the mother and the infant. Therefore, the nursing intervention should be carried out in order to change the negative perception of mothers towards their infants into the positive perception reduce the parenting stress.

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혈액투석 환자의 빈혈관리에서 Erythropoietin 반응에 영향을 미치는 인자 (Determinants of Erythropoietin Hyporesponsiveness in Management of Anemia in Hemodialysis Patients)

  • 신승희;지은희;이영숙;오정미
    • 한국임상약학회지
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    • 제21권2호
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    • pp.122-130
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    • 2011
  • Objective: Although recombinant human erythropoietin (rhEPO) has revolutionized the treatment of anemia in chronic kidney disease (CKD) receiving hemodialysis (HD) with no need of blood transfusion, some patients have a blunted or appear to be resistant to rhEPO. There is a controversy in the causes of rhEPO resistance in maintenance HD patients with anemia. This study is to examine current anemia treatment outcomes and the factors influencing the rhEPO responsiveness in HD patient with CKD. Methods: The clinical parameters or factors relating to erythrompoietin treatment outcomes and erythropoietin responsiveness were collected from the HD patients in two large dialysis centers for three months. The collected paramenters included serum iron, total iron biding capacity (TIBC), transferrin saturation rate, ferritin, albumin, intact PTH, C-reactive protein (CRP), nPCR and medications such as an angiotensin converting enzyme inhbitor, an angiotension II receptor blocker and an HMG-CoA reductase inhibitor (HMG-CoA RI). The data were analyzed to examine the degree of acheiveing the anemia treatment goal and factors relating to ERI. Results: Among total 111 patients, 42 (42.3%) and 47 (37.8%) patients achieved the target Hct and Hb based on the Health Insurance Review and Assessment Services (HIRA) reimbursement criteria. In the higher ERI group (upper quartile), the patients had higher CRP levels (0.5 mg/dl) (p=0.0096), and lower TIBC score (<$240{\mu}g/dl$) (p=0.0027), and less patients were taking HMG-CoA RI (p=0.0019). Male patients (p=0.0204), patients with high TIBC score ($R^2$=0.084, p=0.0021) and patients taking HMG-CoA RI (p=0.0052) required to administer less dose of rhEPO meaning higher erythropoietin responsiveness. Conclusion: Less than 50% of CKD patients were achieving the goals of anemia by erythropoietin administration in large hospitals in Korea even though the goals were lower than those of NKF-K/DOQI practice guideline. The factors influencing ERI were sex, TIBC and HMG-CoA RI administration status, and neither an ACEI nor an ARB did not influence ERI.

고농도 수은 노출자의 혈 중 및 뇨 중 수은 농도 변화에 관한 연구 (Patterns of Mercury Concentrations in Blood and Urine After High Mercury Exposure)

  • 윤충식;임상혁;하권철
    • 한국환경보건학회지
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    • 제27권3호
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    • pp.71-80
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    • 2001
  • Blood and urine mercury level of three workers were monitored during 60~80 days after high exposure to mercury at the silver refining plant. Mercury was used to form silver-mercury amalgam from plating sludge. Workers were exposed to mercury about 70 days at the several processes, such as hand held weaving, vibration table, and heating from the furnace. mercury was analysed by atomic absorption spectroscopy-vapor generation technique. Recovery from the biological sample was 95.51% and pooled standard deviation was 0.033. At the time of study, there was no work at the workplace. So, airborne mercury concentration was measured with area sampling 5 days after the work, ranged from 0.1459 to 1.2351 mg/㎥(Arithmatic mean 0.4711 mg/㎥, Geometric mean 0.3566 mg/㎥) at the inside of the plant, that is far above the ACGIH's TLV(0.025 mg/㎥) and ranged from 0.0073 to 0.0330 mg/㎥ at the outdoor. Blood mercury levels at the beginning of the monitoring were 4~14 times greater than the American Conference of Governmental Industrial Hygienists Biological Exposure Index(ACGIH BEI, 15 ug/L). Blood mercury levels were decreased logarithmically, that is, rapidly at the high level and slowly at the low level but sustained above the level of the ACGIH BEI 60~80 days after the work. Urine mercury levels at the beginning of the monitoring were 8~16 times greater than the ACGIH BEI(35 ug/g creatinine). Urine mercury levels were decreased logarithmically, but correlation between urine level and off-days were lower than those of blood. Decreasing pattern of blood mercury levels were little affected than that of urine levels when the chelating agent, D-penicillamine, was administered. There was correlation between blood mercury level and urine mercury level(0.81~0.83) but it didn\`t mean that the highest blood mercury level corresponded the highest urine mercury level. In our study, Case 1 always shows the highest level in urine but case 3 always shows the highest level in blood. Creatinine correction represented better correlations between urine mercury levels and blood levels, and between urine levels and off-days rather than by urine volume. Spot urine sampling had a wide variation than that of whole day urine sampling. So, We recommend spot urine sampling for screening and whole day urine sampling for exact diagnosis.

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