• Archives of Pharmacal Research
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• v.24 no.6
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• pp.514-517
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• 2001

In order to find potent virus-cell fusion inhibitory components from Korean edible clams, thirteen prepared polysaccharides were introduced to syncytia formation inhibition assay, which is based on the interaction between the HIV-1 envelope protein gp 120/41 and the cellular membutane protein CD4 of T lymphocytes. Among them, Meretrix petechialis showed a potent viruscell fusion inhibitory activity. Fusion index (F1) and percent (%) fusion inhibition of the polysaccharide of this clam were $0.21{\pm}0.02$, and $67.52{\pm}4.09$ at 100781m1, respectively. It exhibited almost equivalent virus-cell fusion inhibitory activity to that of dextran sulfate which was used as a standard control.

• Journal of Digital Convergence
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• v.12 no.12
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• pp.227-232
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• 2014

Technology convergence is a global megatrends. In addition, developed contries should study for the new technology convergence production. Index of technology convergence has side effects that increase the value of production in the technology convergence and add to difference list about plan, however, this is difficult to verify. This paper presents a method to maintain consistency using list and confirm this when evaluation.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.36 no.5
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• pp.413-422
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• 2018

Many applications using satellite data from high-resolution multispectral sensors require an image fusion step, known as pansharpening, before processing and analyzing the multispectral images when spatial fidelity is crucial. Image fusion methods are to improve images with higher spatial and spectral resolutions by reducing spectral distortion, which occurs on image fusion processing. The image fusion methods can be classified into MRA (Multi-Resolution Analysis) and CSA (Component Substitution Analysis) approaches. To suggest the efficient image fusion method for Pleiades and KOMPSAT (Korea Multi-Purpose Satellite) 3 satellites, this study will evaluate image fusion methods for multispectral and panchromatic images. HPF (High-Pass Filtering), SFIM (Smoothing Filter-based Intensity Modulation), GS (Gram Schmidt), and GSA (Adoptive GS) were selected for MRA and CSA based image fusion methods and applied on multispectral and panchromatic images. Their performances were evaluated using visual and quality index analysis. HPF and SFIM fusion results presented low performance of spatial details. GS and GSA fusion results had enhanced spatial information closer to panchromatic images, but GS produced more spectral distortions on urban structures. This study presented that GSA was effective to improve spatial resolution of multispectral images from Pleiades 1A and KOMPSAT 3.

• Korean Journal of Remote Sensing
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• v.28 no.1
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• pp.39-54
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• 2012

The objective of this study is to propose efficient data fusion techniques feasible to the KOMPSAT-2 satellite images. The most widely used image fusion techniques, which are the high-pass filter (HPF), the intensity-hue-saturation-based (modified IHS), the pan-sharpened, and the wavelet-based methods, was applied to four KOMPSAT - 2 satellite images having different regional and seasonal characteristics. Each fusion result was compared and analyzed in spatial and spectral features, respectively. Quality evaluation of image fusion techniques was performed in both quantitative and visual analysis. The quantitative analysis methods used for this study were the relative global dimensional error (spatial and spectral ERGAS), the spectral angle mapper index (SAM), and the image quality index (Q4). The results of quantitative and visual analysis indicate that the pan-sharpened method among the fusion methods used for this study relatively has the suitable balance between spectral and spatial information. In the case of the modified IHS method, the spatial information is well preserved, while the spectral information is distorted. And also the HPF and wavelet methods do not preserve the spectral information but the spatial information.

• Korean Journal of Remote Sensing
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• v.26 no.5
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• pp.581-591
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• 2010

In this paper, we proposed a new wavelet-based image fusion algorithm, which has advantages in both frequency and spatial domains for signal analysis. The developed algorithm compares the ratio of SAR image signal to optical image signal and assigns the SAR image signal to the fused image if the ratio is larger than a predefined threshold value. If the ratio is smaller than the threshold value, the fused image signal is determined by a weighted sum of optical and SAR image signal. The fusion rules consider the ratio of SAR image signal to optical image signal, image gradient and local variance of each image signal. We evaluated the proposed algorithm using Ikonos and TerraSAR-X satellite images. The proposed method showed better performance than the conventional methods which take only relatively strong SAR image signals in the fused image, in terms of entropy, image clarity, spatial frequency and speckle index.

• Korean Journal of Pharmacognosy
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• v.34 no.1 s.132
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• pp.28-32
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• 2003

In order to search for the anti-HIV agents from natural products, eighty MeOH extracts of medicinal plants were applied to a syncytia formation inhibition assay which is based on the interaction between the HIV-1 envelope glycoprotein gp120/gp41 and the cellular membrane protein CD4 of T lymphocytes. Among them, Ailanthus altissima showed a potent virus-cell fusion inhibitory activity. Repeated column chromatoghaphy of the methylene chloride fraction of A. altissima afforded compounds 1$({\beta}-sitosterol-3-O-{\beta}-D-glucoside)$, 2(tetramethoxycoumarin), and 3(ocotillone). Virus-cell fusion inhibitory activity of compound 3(ocotillone) was $70.76{\pm}4.09%$ at the concentration of $100\;{\mu}g/ml$.

• Journal of Korean Neurosurgical Society
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• v.59 no.4
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• pp.363-367
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• 2016

Objective : To compare the fusion rate of a hydroxyapatite demineralized bone matrix (DBM) with post-laminectomy acquired autograft in lumbar interbody fusion surgery and to evaluate the correlation between fusion rate and clinical outcome. Methods : From January 2013 to April 2014, 98 patients underwent lumbar interbody fusion surgery with hydroxyapatite DBM (HA-DBM group) in our institute. Of those patients, 65 received complete CT scans for 12 months postoperatively in order to evaluate fusion status. For comparison with autograft, we selected another 65 patients who underwent lumbar interbody fusion surgery with post-laminectomy acquired autograft (Autograft group) during the same period. Both fusion material groups were matched in terms of age, sex, body mass index (BMI), and bone mineral density (BMD). To evaluate the clinical outcomes, we analyzed the results of visual analogue scale (VAS), Oswestry Disability Index (ODI), and Short Form Health Survey (SF-36). Results : We reviewed the CT scans of 149 fusion levels in 130 patients (HA-DBM group, 75 levels/65 patients; Autograft group, 74 levels/65 patients). Age, sex, BMI, and BMD were not significantly different between the groups (p=0.528, p=0.848, p=0.527, and p=0.610, respectively). The HA-DBM group showed 39 of 75 fused levels (52%), and the Autograft group showed 46 of 74 fused levels (62.2%). This difference was not statistically significant (p=0.21). In the HA-DBM group, older age and low BMD were significantly associated with non-fusion (61.24 vs. 66.68, p=0.027; -1.63 vs. -2.29, p=0.015, respectively). VAS and ODI showed significant improvement after surgery when fusion was successfully achieved in both groups (p=0.004, p=0.002, HA-DBM group; p=0.012, p=0.03, Autograft group). Conclusion : The fusion rates of the hydroxyapatite DBM and Autograft groups were not significantly different. In addition, clinical outcomes were similar between the groups. However, older age and low BMD are risk factors that might induce non-union after surgery with hydroxyapatite DBM.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.2 no.1
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• pp.17-31
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• 1989

This study was under taken to investigate the healing of Sa Gun Ja Tang extract (SE) and Sa Gun Ja Tang added Radix Astragali extract (SHE) on the artificial wound on rabbit skin. The granulation tissues were observed by microscope at the five day interval for twenty days. In order to understand the healing mechanism chick embryo culture was carried out in the presence of the extracts and the growth ratio and fusion index were counted. The results obtained were as follows: 1. The healing power of SE treated group on wound was more significant than the control group. 2. The healing power on wound was more effective at the SHE than the SE. 3. The growth ratio and fusion index were higher at the SHE treated groups than the SE treated groups. From the above result, SHE was more effective than the SE on wound healing activity by the mechanism of stimulating the cell growth ratio and fusion index.

• Aerospace Engineering and Technology
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• v.8 no.2
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• pp.26-32
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• 2009

In the satellite image fusion, the most important point is to preserve both the spatial detail of panchromatic(PAN) image and the spectral information of multispectral(MS) image. Among various image fusion techniques, fusion technique using Intensity-Hue-Saturation(IHS) transform is widely used and it has advantage that computation is very simple. In this study, a fusion technique using fast IHS transform and trade-off parameter $\alpha^i$ proposed. Proposed fusion technique permits customization of the trade-off between the spectral information and spatial detail quality of the fused image through the evaluation of two quality indices: a spectral index(the spectral ERGAS) and a spatial one(the spatial ERGAS). Based on the result of experiment using IKONOS image, we confirmed the proposed fusion technique was more effective in preserving spatial detail and spectral information than existing fusion techniques using fast IHS transform.

• Journal of Korean Society for Geospatial Information Science
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• v.21 no.2
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• pp.63-69
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• 2013

Change detection technique is essential to various applications of Very High-Resolution(VHR) satellite imagery and land monitoring. However, change detection accuracy of VHR satellite imagery can be decreased due to various geometrical dissimilarity. In this paper, the existing fusion evaluation indexes were revised and applied to improve VHR imagery based change detection accuracy between multi-temporal images. In addition, appropriate change detection methodology of VHR images are proposed through comparison of general change detection algorithm with cross-sharpened image based change detection algorithm. For these purpose, ERGAS, UIQI and SAM, which were representative fusion evaluation index, were applied to unsupervised change detection, and then, these were compared with CVA based change detection result. Methodologies for minimizing the geometrical error of change detection algorithm are analyzed through evaluation of change detection accuracy corresponding to image fusion method, also. The experimental results are shown that change detection accuracy based on ERGAS index by using cross-sharpened images is higher than these based on other estimation index by using general fused image.