• Communications for Statistical Applications and Methods
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• 제25권6호
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• pp.619-631
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• 2018

Functional data analysis continues to attract interest because advances in technology across many fields have increasingly permitted measurements to be made from continuous processes on a discretized scale. Particulate matter is among the most harmful air pollutants affecting public health and the environment, and levels of PM10 (particles less than 10 micrometers in diameter) for regions of California remain among the highest in the United States. The relatively high frequency of particulate matter sampling enables us to regard the data as functional data. In this work, we investigate the dominant modes of variation of PM10 using functional data analysis methodologies. Our analysis provides insight into the underlying data structure of PM10, and it captures the size and temporal variation of this underlying data structure. In addition, our study shows that certain aspects of size and temporal variation of the underlying PM10 structure are associated with changes in large-scale climate indices that quantify variations of sea surface temperature and atmospheric circulation patterns.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2008년도 춘계학술대회 논문집
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• pp.1802-1808
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• 2008

Recent interest in the construction sector, rising about the environment and eco-friendly recycled material resources, and increase the development of method But despite these efforts, and the diverse functional and structural changes in the structure can not be an appropriate response to the functional waterproof structural changes in the structures and appropriate response Diversification does not waterproof and functional issues such as durability, and which are occurring due to the structure to secure stability and durability, never sees the conservative economic losses due to import constructability reinforcement situation. Therefore, this study applies to structure the existing waterproof method (hereinafter referred to as structures water-resistant methode), and to review recent issues of environmental pollution and resource waste, and taking on environmental issues, such as Revelation and functional Inorganic mixed in a way to leverage the manufacturing water-resistant material "Re Inorganic, functional and environmentally friendly high-viscosity mix asphalt waterproof rubber reinforcements, and taking conservative" for the characterization and performance assessment to the issues raised by the structure and whether the judge would respond.

• 한국항공우주학회지
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• 제40권2호
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• pp.157-164
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• 2012

다기능 구조체는 전자장비, 열제어 부품, 우주복사 차폐물 및 지지구조물이 하나의 시스템으로 통합된 구조적 결합체로써, 위성 및 행성탐사선 모듈의 소형화/경량화를 달성하여 경제성을 획기적으로 향상시킬 수 있는 매우 중요한 첨단 모듈이다. 본 연구에서는 구조적인 강도를 고려하여 설계된 다기능 구조체의 6가지 형상에 대하여 방열성능을 수치해석적인 방법으로 검토하였다. 다기능 구조체의 rib 형상이 방열판 내 전열효과에 미치는 영향은 열전도 측면만을 고려하는 것은 의미가 없으며, 구조적인 강성, 제작의 난점, 무게 등을 모두 고려하여야 하고, 전열 측면에서는 rib의 형상보다 면재 외부층의 두께와 무게에 대한 trade-off를 통하여 최적화하는 것이 일반적으로 유효하다고 판단된다.

• 미생물학회지
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• 제29권4호
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• pp.209-214
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• 1991

The PRD1 DNA polymerase is a small multi-functional enzyme containing conserved amino acid sequences shared by family B DNA polymerases. Thus the PRD1 DNA polymerase provides an useful model system with which to study structure-functional relationships of DNA polymerase molecules. In order to investigate the functional and structural roles of the highly conserved amino acid sequences, we have introduced three mutations into a conserved amino acid of the PRD1 DNA polymerase. Genetic complememtation study indicated that each mutation inactivated DNA polymerase catalytic activity.

• 대한안전경영과학회지
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• 제15권3호
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• pp.133-141
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• 2013

As a work analysis technique, Work Domain Analysis (WDA) aims to identify the design knowledge structure of a work domain that human operators interact with through human-system interfaces. Abstraction hierarchy (AH) is a multi-level, hierarchical knowledge representation framework for modeling the functional structure of any kinds of systems. Thus, WDA based on AH aims to identify the functional knowledge structure of a work domain. AH has been used in a range of work domains and problems to model their functional knowledge structure and has proven its generality and usefulness. However, many of researchers and system designers have reported that it is never easy to understand the concepts underlying AH and use it effectively for WDA. This would be because WDA is a form of work analysis that is different from other types of work analysis techniques such as task analysis and AH has several unique characteristics that are differentiated from other types of function analysis techniques used in systems engineering. With this issue in mind, this paper introduces the concepts of WDA based on AH and offers a comprehensive list of references. Next, this paper proposes a set of principles for effectively applying AH for work domain analysis, which are developed based on the author's experiences, consultation with experts, and literature reviews.

• 설비공학논문집
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• 제19권8호
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• pp.607-614
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• 2007

This paper investigated that the functional group and chemical structure of additives affect ice adhesion in aqueous solutions cooling with stirring. In order to compare the effect on the ice adhesion in aqueous solutions, the functional group like carboxyl (-COOH), hydroxyl(-OH) or amine($-NH_{2}$) one were compared each other. Among the functional group, the strength of the hydrogen bonding force order is amine, hydroxyl and carboxyl one. It supports that ethylene diamine 7 mass% solution including amine group was effective to suppress the ice adhesion, though it is corrosive. Also, the ice adhesion were effectively resisted and formed lots of ice slurries in cooling experiment of 7 mass% solution of 1, 2-and 1, 3-propanediol which is different molecular structure but equal molecular weight each other.

• 한국의류학회지
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• 제37권3호
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• pp.247-259
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• 2013

This study conceptually approaches and clearly compares the similarities and differences of fashion and architecture through a focus on their correlations. This study identifies the conceptual definitions of functional minimalism by an examination of function that represents the largest similarity between architecture and fashion. This study classifies the nature of functional minimalism and studies cases for each architectural classification in the areas of: the simplicity of a structure, unitarity pursuit of economic value, repeatability in an efficiency unit, reducibility stressing property, and multi-functional spatiality. The characteristics of functional minimalism fashion are distinguish as: simplicity in a structure that highlight structural lines in non-decorated design, unitarity pursuit of economic value represented in united process and pattern for its economic effect, repeatability in an efficiency unit represented through the repeated decoration of a functional unit, reducibility stressing a property that emphasizes property with a dominant design element through a highlight of the characteristics of materials and multi-functional spatiality that represents variability in clothes through an expansion of limited spatial function. This study approaches each discipline with a clear understanding of the differences between the two and suggests standards for a comparative study of architecture and fashion.

• Genomics & Informatics
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• 제19권4호
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• pp.43.1-43.12
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• 2021

Campylobacter jejuni is one of the most prevalent organisms associated with foodborne illness across the globe causing campylobacteriosis and gastritis. Many proteins of C. jejuni are still unidentified. The purpose of this study was to determine the structure and function of a non-annotated hypothetical protein (HP) from C. jejuni. A number of properties like physiochemical characteristics, 3D structure, and functional annotation of the HP (accession No. CAG2129885.1) were predicted using various bioinformatics tools followed by further validation and quality assessment. Moreover, the protein-protein interactions and active site were obtained from the STRING and CASTp server, respectively. The hypothesized protein possesses various characteristics including an acidic pH, thermal stability, water solubility, and cytoplasmic distribution. While alpha-helix and random coil structures are the most prominent structural components of this protein, most of it is formed of helices and coils. Along with expected quality, the 3D model has been found to be novel. This study has identified the potential role of the HP in 2-methylcitric acid cycle and propionate catabolism. Furthermore, protein-protein interactions revealed several significant functional partners. The in-silico characterization of this protein will assist to understand its molecular mechanism of action better. The methodology of this study would also serve as the basis for additional research into proteomic and genomic data for functional potential identification.

• Current Optics and Photonics
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• 제7권2호
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• pp.157-165
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• 2023

We propose a highly directional waveguide grating antenna for an optical phased array, achieving high directionality of more than 97% by interleaving the trenches with different etching depths in the silicon nitride layer, and adopting a multilayered structure. Meanwhile, the multilayered structure reduces the perturbation strength, which enables a centimeter-scale radiation length. The beam-steering range is 13.2°, with a wavelength bandwidth of 100 nm. The 1-dB bandwidth of the grating is 305 nm. The multilayered grating structure has a large tolerance to the fabrication variation and is compatible with CMOS fabrication techniques.

• BMB Reports
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• 제48권2호
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• pp.81-90
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• 2015

p73 is a structural and functional homologue of the p53 tumor suppressor protein. Like p53, p73 induces apoptosis and cell cycle arrest and transactivates p53-responsive genes, conferring its tumor suppressive activity. In addition, p73 has unique roles in neuronal development and differentiation. The importance of p73-induced apoptosis lies in its capability to substitute the pro-apoptotic activity of p53 in various human cancer cells in which p53 is mutated or inactive. Despite the great importance of p73-induced apoptosis in cancer therapy, little is known about the molecular basis of p73-induced apoptosis. In this review, we discuss the p73 structures reported to date, detailed structural comparisons between p73 and p53, and current understanding of the transcription-dependent and -independent mechanisms of p73-induced apoptosis.