• Journal of the Korean Society of Physical Medicine
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• v.15 no.2
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• pp.109-120
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• 2020

PURPOSE: This study was conducted to verify the effects of a functional correction of the pain of patients with chronic low back pain(CLBP), and to examine the effect of dysfunctional factors on health-related quality of life. METHODS: A preliminary survey was first conducted on 90 patients with CLBP after functional orthodontic treatment. Some revised questionnaires were also prepared. The survey was distributed for approximately eight weeks, and 215 copies were used as the final analysis data, except for questionnaires that were inadequate, error or non-response. RESULTS: Path analysis using the structural equation model of CLBP patients showed a positive correlation between all the path coefficients and the potential factors. The multidimensional relationship between pain and dysfunction after orthognathic treatment was confirmed using three subdivisions of the pain variables as independent variables and the dysfunctional variables as the dependent variables. Multiple regression analysis was performed to examine the effects of pain on the dysfunction. To identify the multidimensional relationship between dysfunction and the health-related quality of life, eight sub-factors of dysfunctional variables were set as the independent variables, and multiple regression was analyses were performed with the dependent variables of the health-related quality of life. CONCLUSION: This study examined the structural and influence relationships of the functional correction with pain, dysfunction, and health-related quality of life. The results, suggest that a functional orthodontic treatment can be used as a positive program for the health-related quality of life. In addition, this study is meaningful in that it provieds useful information for intervention such as psychosocial change of patients.

• The Journal of Korean Physical Therapy
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• v.32 no.4
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• pp.203-209
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• 2020

Purpose: This study examined the effects of a physical stability exercise program on the functional movement and balance of middle school volleyball players to provide future management and training data to improve the performance of volleyball players. Methods: The subjects were 20 volleyball players from Y Middle School in Mokpo. The results of comparing and analyzing the effects of the physical stability exercise program on the functional movement and balance of middle school volleyball players for 10 weeks are as follows. Results: The number of participants who showed power and agility (p<0.01) was increased significantly, and the response time was shortened significantly (p<0.01). On the evaluation of functional movement, the total score showed a significant difference between the pre-test at 10.90±1.30 points and the post-test at 13.81±.60 (p<0.001). The subjects' balance showed a significant difference from 84.11±7.53 to 97.65±8.47 (p<0.001), and the Right Composite Score showed a significant difference from 83.74±6.64 to 97.27±8.48 (p<0.001). Conclusion: The application of a physical stability exercise program for 10 weeks is effective in improving the speed, agility, functional movement, and balance to volleyball players who are weakened and at risk of injury. This is believed to prevent or reduce injury.

• Food Science and Preservation
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• v.15 no.3
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• pp.396-404
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• 2008

This study investigated the functional properties of lateral roots of red ginseng following roasting treatment The ten different conditions, based on the central composite design for roasting parameters, were pre-established according to roasting temperature($140{\sim}240^{\circ}C$) and time($5{\sim}25\;min$). The functional characteristics were monitored using response surface methodology, whereby polynomial equations and correlation coefficients were investigated between roasting conditions. The functional properties of the samples were affected more by roasting time than temperature. The optimal roasting condition ranges for maximizing the functional qualities of lateral roots of red ginseng were predicted to be a roasting temperature of $194.5-210.9^{\circ}C$, and a roasting time of 13.8-20.0 min.

• Journal of Neurogastroenterology and Motility
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• v.24 no.4
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• pp.512-527
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• 2018

This review provides a comprehensive overview of brain imaging studies of the brain-gut interaction in functional gastrointestinal disorders (FGIDs). Functional neuroimaging studies during gut stimulation have shown enhanced brain responses in regions related to sensory processing of the homeostatic condition of the gut (homeostatic afferent) and responses to salience stimuli (salience network), as well as increased and decreased brain activity in the emotional response areas and reduced activation in areas associated with the top-down modulation of visceral afferent signals. Altered central regulation of the endocrine and autonomic nervous responses, the key mediators of the brain-gut axis, has been demonstrated. Studies using resting-state functional magnetic resonance imaging reported abnormal local and global connectivity in the areas related to pain processing and the default mode network (a physiological baseline of brain activity at rest associated with self-awareness and memory) in FGIDs. Structural imaging with brain morphometry and diffusion imaging demonstrated altered gray- and white-matter structures in areas that also showed changes in functional imaging studies, although this requires replication. Molecular imaging by magnetic resonance spectroscopy and positron emission tomography in FGIDs remains relatively sparse. Progress using analytical methods such as machine learning algorithms may shift neuroimaging studies from brain mapping to predicting clinical outcomes. Because several factors contribute to the pathophysiology of FGIDs and because its population is quite heterogeneous, a new model is needed in future studies to assess the importance of the factors and brain functions that are responsible for an optimal homeostatic state.

• Journal of Naturopathy
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• v.9 no.1
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• pp.33-36
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• 2020

Purpose: For the health of pet dogs and to reduce harm to humans, we investigated the preference of pet dogs on cushions made from functional ocher textile, which is known to be beneficial to human health. Methods: The preference of 12 small dogs between cushions made using functional ocher textile and normal yellow colored fabrics was observed. Results: The observation study showed 83.3% preference on cushions made from functional ocher textile where dogs rested or slept mostly. The biting behavior was improved by 83.3%. After using the functional cushions, four dogs with eye disease, one with eczema, and two with allergy showed improvements while others showed no improvement. After the experience, 50% of dogs became quieter. 87.5% of dogs showed more mild temperament. Conclusions: The functional ocher cushions showed preferences by dogs as well as brought positive improvements with the temperament and health conditions. This study proves to be a valuable fundamental research in this field of functional ocher cushions.

• Journal of Biomedical Engineering Research
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• v.45 no.1
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• pp.26-36
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• 2024

Functional brain imaging techniques have been used to diagnose psychiatric disorders such as dementia, depression, and autism. Recently, these techniques have also been actively used to study hearing loss. The present study reviewed the application of the functional brain imaging techniques in auditory research, especially those focusing on hearing loss, over the past decade. EEG, fMRI, fNIRS, MEG, and PET have been utilized in auditory research, and the number of research studies using these techniques has been increasing. In particular, fMRI and EEG were the most frequently used technique in auditory research. EEG studies mostly used event-related designs to analyze the direct relationship between stimulus and the related response, and in fMRI studies, resting-state functional connectivity and block designs were utilized to analyze alterations in brain functionality in hearing-related areas. In terms of age, while studies involving children mainly focused on congenital and pre- and post-lingual hearing loss to analyze developmental characteristics with and without hearing loss, those involving adults focused on age-related hearing loss to investigate changes in the characteristics of the brain based on the presence of hearing loss and the use of a hearing device. Overall, ranging from EEG to PET, various functional brain imaging techniques have been used in auditory research, but it is difficult to perform a comprehensive analysis due to the lack of consistency in experimental designs, analysis methods, and participant characteristics. Thus, it is necessary to develop standardized research protocols to obtain high-quality clinical and research evidence.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.57 no.3
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• pp.262-277
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• 2024

The mid-eastern coast of Korea is located at the boundary between cold and warm currents, which causes changes in the distribution and composition of marine organisms in response to fluctuations in the marine environment. To understand the seasonal changes in the seaweed community, we investigated its species composition, biomass, coverage, and frequency from November 2022 to August 2023. A total of 45 species (7 green, 18 brown, and 20 red algae) were found in the study area. In the intertidal zone, the number of species decreased from autumn to summer; the biomass peaked during winter (471.94 g wet weight m^-2). Seaweed groups were the dominant functional groups, which were coarsely branched, filamentous, and sheet-like during autumn, winter, spring, and summer. The morpho-functional group was dominated by turf species. In the subtidal zone, the number of species increased during autumn to spring, whereas the biomass peaked during spring (655.27 g wet weight m^-2). The functional group was dominated by coarsely branched species throughout all four seasons, whereas the morpho-functional group was dominated by canopy species. Consequently, changes in the biomass of brown and red algae are recognized as key drivers of seasonal changes in seaweed communities.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.3
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• pp.1819-1823
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• 2013

Objective: Microarray data were analyzed to explore key genes and their functions in progression of colorectal cancer (CRC). Methods: Two microarray data sets were downloaded from Gene Expression Omnibus (GEO) database and differentially expressed genes (DEGs) were identified using corresponding packages of R. Functional enrichment analysis was performed with DAVID tools to uncover their biological functions. Results: 631 and 590 DEGs were obtained from the two data sets, respectively. A total of 32 common DEGs were then screened out with the rank product method. The significantly enriched GO terms included inflammatory response, response to wounding and response to drugs. Two interleukin-related domains were revealed in the domain analysis. KEGG pathway enrichment analysis showed that the PPAR signaling pathway and the renin-angiotensin system were enriched in the DEGs. Conclusions: Our study to systemically characterize gene expression changes in CRC with microarray technology revealed changes in a range of key genes, pathways and function modules. Their utility in diagnosis and treatment now require exploration.

• Journal of Oriental Neuropsychiatry
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• v.8 no.1
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• pp.151-165
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• 1997

The primary purpose of this study was to assess the relation of stress perception and poststroke. This study was done on 50 stroke patients in hospital. According to activities of functional impairment, they were classified into walking disturbance, motor weakness, dysphagia, or reattack etc. The stress perception test(GARS Scles) and stress response assessment shows the follwing results. 1. On the distribution in the stroke 50 patients, For the majority group were male in sex, sixty inage, middle towns people in residence. 2. On the comprehensive GARS scale scores, It marked the higest scores thirty at age, merchandise or salesman on jobs, a city in residence. There was no signigicant difference in mean GARS Scales scores between males and females group, the left hemiplegia and the Rt hemiplegia. 3. On the comprehensive GARS Scale tests, Overall glogal stressor(G8) and sickness stresor(G4) marked the highest scores of all GARS Scales. 4. On the comparative assessment of each group's stress reponse test scores, zung-bu(中腑) was showed higher scores than the other group in oriental diagnosis and hemorrage was showed higher scores than the other group in western medical diagnosis. 5. On the comprehensive assessment of each group's stress reponse test scores, aphsia(不語) marked the highest scores in another disphagia group's. It marked the highest scores in another group's that banshinbulsoo(半身不遂) as regards as hemiplegia generally. Standing disability is the higher scores than another group's walking alone or assist, and standing alone. 6. Secondary attack is the highest scores of all reattack stroke on the stress repones test. 7. Comparing and analyzing the GARS Scale total scores and GARS Scale subject fator at stroke, we found that sickness stressor and fininial stressor is showed the highest correlated to stress response fowlloing stroke. With those results, we can see that functional impairment following stroke is correlated to stress perception and reponse. In the furture studies using, we hope that the findings the study would have clinical relevance to the psychosocial adjustment and total rehabilation of stroke patients.

• Korean Journal of Organic Agriculture
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• v.20 no.1
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• pp.91-99
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• 2012

This study was conducted to develop a functional feed additive for pig with spent $Lycium$ $chinense$ Mill fruit. We investigated the optimum conditions for the extraction of polyphenol from spent $Lycium$ $chinense$ Mill using methanol. Methanol concentration as a solvent for extraction, extraction time and the volume of solvent per a gram of solid (ground spent Lyceum chinense Mill) were selected as parameters. Three levels of parameters were configured according to Box Behnken experiment design, a fractional factorial design, and total 15 trials were employed. Total polyphenol concentration from each trial was used as response from experiment system and effects of parameters on total polyphenol extraction efficiency were determined using response surface model. As a result, all terms in analysis of variance, regression ($p$ = 0.001), linear ($p$ = 0.002), square ($p$ = 0.017) and interaction ($p$ = 0.047) was significant and adjusted determination coefficient ($R^2$) was 94.7%. Total polyphenol extraction efficiency was elevated along increased methanol content and decreased solvent to solid ratio. However extraction time did not affect the efficiency. This study provides a primary information for the optimum extraction conditions to maximize total polyphenol recovery from spent Lycium chinens Mill fruit and this result could be applied to re-use of argo-industrial by-products and to develop of functional feed additives in organic farming.