• Bulletin of the Korean Mathematical Society
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• v.33 no.3
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• pp.359-366
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• 1996

A linear map T from a Banach algebra A into a Banach algebra B is almost multiplicative if $\left\$\mid$ T(fg) - T(f)T(g) \right\$\mid$ \leq \in\left\$\mid$ f \right\$\mid$\left\$\mid$ g \right\$\mid$(f,g \in A)$ for some small positive $\in$. B.E.Johnson [4,5] studied whether this implies that T is near a multiplicative map in the norm of operators from A into B. K. Jarosz [2,3] raised the conjecture : If T is an almost multiplicative functional on uniform algebra A, there is a linear and multiplicative functional F on A such that $\left\$\mid$ T - F \right\$\mid$ \leq \in', where \in' \to 0$ as $\in \to 0$. B. E. Johnson [4] gave an example of non-uniform commutative Banach algebra which does not have the property described in the above conjecture. He proved also that C(K) algebras and the disc algebra A(D) have this property [5]. We extend this property to a derivation on a Banach algebra.

• The Plant Pathology Journal
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• v.36 no.2
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• pp.185-191
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• 2020

Streptomyces griseus S4-7, a well-characterized keystone taxon among strawberry microbial communities, shows exceptional disease-preventing ability. The whole-genome sequence, functional genes, and bioactive secondary metabolites of the strain have been described in previous studies. However, proteomics studies of not only the S4-7 strain, but also the Streptomyces genus as a whole, remain limited to date. Therefore, in the present study, we created a proteomics reference map for S. griseus S4-7. Additionally, analysis of differentially expressed proteins was performed against a wblE2 mutant, which was deficient in spore chain development and did not express an antifungal activity-regulatory transcription factor. We believe that our data provide a foundation for further in-depth studies of functional keystone taxa of the phytobiome and elucidation of the mechanisms underlying plant-microbe interactions, especially those involving the Streptomyces genus.

• Journal of Korean Dental Science
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• v.17 no.4
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• pp.163-173
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• 2024

The terminal differentiation of odontoblasts is characterized by specific molecular markers that reflect their functional maturity. This review explores both canonical markers, such as Dentin Sialophosphoprotein (DSPP), Dentin Matrix Protein 1 (DMP1), Nestin, and Alkaline Phosphatase (ALP), and emerging markers like MAP1B, MAP Tau, and β-catenin. These markers offer valuable insights into the regulation of odontoblast differentiation and the maintenance of their polarized, dentin-secreting phenotype. The review further discusses the experimental applications of these markers in in vitro studies, dental tissue engineering, regenerative endodontics, and drug discovery. Canonical markers are utilized to confirm the maturity of odontoblasts and evaluate bioengineered tissues, while emerging markers reveal potential new targets for enhancing dentin repair and regeneration. Additionally, the role of signaling pathways, including Wnt5a, BMP, and integrin-mediated pathways, in supporting the structural and functional characteristics of mature odontoblasts is discussed. By consolidating current knowledge on these markers and pathways, this review aims to advance the understanding of odontoblast biology and contribute to the development of innovative strategies for dental tissue engineering and regenerative therapies.

• Spatial Information Research
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• v.5 no.2
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• pp.147-160
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• 1997

"The "Map Algebra", beeing recognized as a viable theoretical framework for GIS (Geographica Infonnation System), models map layers as "operands" which are the basic unit of geo-processing, and a variety of GIS commands as "operators." In this paper, we attempt at lifting some limitations of map algebras proposed in GIS literature. First, we model map layer as "function" such that we may employ the notion of meta operator (or, higher-order funtion) available in the functional programming paradigm. This approach provides map algebraic language with "programmability" needed in GIS user language. Second, we extend the semantics of, and improve on the sytactic structure of map algebraic language. Mer the data model and language associated with map algebra are formalized, we proceed to design and implement a prototype of map algebraic processor. The parser of the language in our prototype plays the role of transforming the native and heterogeneous user language of current GISs into a canonical map algebraic language. The prototype, named "MapSee" is a proof-of-concept system for the ideas we propsed in this paper. We believe that the uniform interface based on the map algebraic language will make promising infrastructure to support "Internet GIS." This is because the uniform but powerful interface through the Web clients allow access to both geo-data and geo-processing resources distributed over the network.to both geo-data and geo-processing resources distributed over the network.

• BMB Reports
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• v.50 no.11
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• pp.535-536
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• 2017

A novel approach has been used to identify functional interactions relevant to human disease. Using high-throughput human-yeast genetic interaction screens, a first draft of disease interactome was obtained. This was achieved by first searching for candidate human disease genes that confer toxicity in yeast, and second, identifying modulators of toxicity. This study found potentially disease-relevant interactions by analyzing the network of functional interactions and focusing on genes implicated in amyotrophic lateral sclerosis (ALS), for example. In the subsequent proof-of-concept study focused on ALS, similar functional relationships between a specific kinase and ALS-associated genes were observed in mammalian cells and zebrafish, supporting findings in human-yeast genetic interaction screens. Results of combined analyses highlighted MAP2K5 kinase as a potential therapeutic target in ALS.

• Journal of Biomedical Engineering Research
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• v.27 no.3
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• pp.110-116
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• 2006

Finite element method (FEM) provides several advantages over other numerical methods such as boundary element method, since it allows truly volumetric analysis and incorporation of realistic electrical conductivity values. Finite element mesh generation is the first requirement in such in FEM to represent the volumetric domain of interest with numerous finite elements accurately. However, conventional mesh generators and approaches offered by commercial packages do not generate meshes that are content-adaptive to the contents of given images. In this paper, we present software that has been implemented to generate content-adaptive finite element meshes (cMESHes) based on the contents of MR images. The software offers various computational tools for cMESH generation from multi-slice MR images. The software named as the Content-adaptive FE Mesh Generation Toolbox runs under the commercially available technical computation software called Matlab. The major routines in the toolbox include anisotropic filtering of MR images, feature map generation, content-adaptive node generation, Delaunay tessellation, and MRI segmentation for the head conductivity modeling. The presented tools should be useful to researchers who wish to generate efficient mesh models from a set of MR images. The toolbox is available upon request made to the Functional and Metabolic Imaging Center or Bio-imaging Laboratory at Kyung Hee University in Korea.

• Anxiety and mood
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• v.10 no.2
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• pp.143-150
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• 2014

Objective : The subgenual cingulate cortex, a part of default-mode network, has been known to playa key role in the pathophysiology of depression. The previous studies have reported abnormal functional connectivity between the subgenual cingulate cortex and other brain regions in the patients with depression. The goal of this shldy was to explore the resting-state functional connectivity of the subgenual cingulate cortex between the patients with depression and healthy subjects. Methods : Twenty patients with major depression and age- and sex-matched 20 healthy subjects underwent 5-minute resting state fMRI scans. The functional connectivity map in each subject was acquired using seed-based correlation analysis with the seed located in the subgenual cingulate cortex (Talairach coordinates; x=-10, y=5, z=-10). The functional connectivity maps were calculated using AFNI and compared between the patient and healthy subject group via two-sample T-test using 3dttest++ in AFNI package. Results : Functional connectivity was decreased between the subgenual cingulate cortex and both sides of fusiform gyrus in depressed subjects. Connectivity was also decreased between the subgenual cingulate cortex and the left cerebellum in the patient group. There was no correlation between the severity of depression and the degree of functional connectivity between the subgenual cingulate cortex and the regions showing decreased functional connectivity. Conclusion : Decreased resting-state functional connectivity between the subgenual cingulate cortex and both sides of fusiform gyrus, and decreased connectivity between the subgenual cingulate cortex and the left cerebellum found in the patients with major depression in comparison to the healthy subjects might be related to abnormal emotional and cognitive processing of depressed patients.

• The korean journal of orthodontics
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• v.50 no.2
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• pp.86-97
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• 2020

Objective: To propose a three-dimensional (3D) method for evaluating temporomandibular joint (TMJ) changes during Twin-block treatment. Methods: Seventeen patients with Class II division 1 malocclusion treated using Twin-block and nine untreated patients with a similar malocclusion were included in this research. We collected their cone beam computed tomography (CBCT) data from before and 8 months after treatment. Segmentations were constructed using ITK-SNAP. Condylar volume and superficial area were measured using 3D Slicer. The 3D landmarks were identified on CBCT images by using Dolphin software to assess the condylar positional relationship. 3D models of the mandible and glenoid fossa of the patients were constructed and registered via voxel-based superimposition using 3D Slicer. Thereafter, skeletal changes could be visualized using 3DMeshMetric in any direction of the superimposition on a color-coded map. All the superimpositions were measured using the same scale on the distance color-coded map, in which red color represents overgrowth and blue color represents resorption. Results: Significant differences were observed in condylar volume, superficial area, and condylar position in both groups after 8 months. Compared with the control group (CG), the Twin-block group exhibited more obvious condyle-fossa modifications and joint positional changes. Moreover, on the color-coded map, more obvious condyle-fossa modifications could be observed in the posterior and superior directions in the Twin-block group than in the CG. Conclusions: We successfully established a 3D method for measuring and evaluating TMJ changes caused by Twin-block treatment. The treatment produced a larger condylar size and caused condylar positional changes.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.18 no.1
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• pp.127-133
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• 2015

Interests in ecosystem services have increased and a number of attempts to perform a quantitative valuation on them have been undertaken. To classify the ecosystem types landcover classification maps are generally used. However, some forest types on landcover classification maps have a number of errors. The purpose of this study is to verify the forest types on the landcover map by using a variety of field survey data and to suggest an improved method for forest type classifications. Forest types are compared by overlaying the landcover classification map with the 4th forest type map, and then they are verified by using National Forest Inventory, 3rd National Ecosystem Survey and field survey data. Misclassifications of forest types are found on the forest on the forest type map and farm and other grassland on the landcover map. Some errors of forest types occur at Daegu, Busan and Ulsan metropolitan cities and Gangwon province. The results of accuracy in comprehensive classification show that deciduous forest is 76.1%; coniferous forest is 54.0%; and mixed forest is 22.2%. In order to increase the classification accuracy of forest types a number of remote sensing images during various time periods should be used and the survey period of NFI and the National Forest Inventory and National Ecosystem Survey should be consistent. Also, examining areas with wide forest patch should be prioritized during the field survey in order to decrease any errors.

• Journal of Korean Society of Archives and Records Management
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• v.16 no.1
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• pp.175-193
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• 2016

A topic map was designed as an efficient information retrieval method that is optimized for classification, organization, and navigation through the use of a semantic link network above information resources. With this, this study aims to design a topic map-based university archives retrieval system to provide the relevant information retrieval. For this study, electronic records that relate to the academic administration within two years of D university were collected, and topic map editing was carried out with Ontopia Omnigator. Topics were classified according to their functional analysis of academic administration. In the end, the number of topics was finalized as 626, with 6 types in general: academic work, staff, college register, student, university, etc. Association was separated into six types as well, which were formed with consideration to the relationships among topics. In addition, there are seven occurrence types: register class, register number, register date, receiver, title, creator, and identifier. It is expected that the associative nature of the designed topic map-based retrieval system in this study will make navigation of large records easy and allow incidental discovery of knowledge.