• Title/Summary/Keyword: Functional Evalution

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Prevention effect of Allium tuberosum extract on ateriosclerosis in LDL Receptor Knockout Mouse (LDL Receptor Knockout Mouse에서 부추추출물의 죽상경화증 예방 효과)

  • Kwon, OJun;Lee, JooYoung;Roh, Seong-Soo
    • The Korea Journal of Herbology
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    • v.31 no.2
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    • pp.13-19
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    • 2016
  • Objectives : The present study was designed to evaluate the protective effect of Allium tuberosum (AT) extract on atherosclerosis in LDL receptor knockout (LDLr KO) mouse fed western diet.Methods : The AT was extracted 70% ethanol. The experimental groups were divided with four groups of LDLr KO mice, one group fed a normal diet and the others fed a Western diets for 8weeks. Two Western diet groups were orally administered AT extract at dosage of 100 and 300 mg/kg body weight. The body weight and food intake were measured every day. We measured levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), triglyceride (TG), total cholesterol (TC), high-density lipoprotein (HDL), low-density lipoprotein (LDL), and Glucose in serum. Also, effect of AT extract performed using H&E staining.Results : The AT treatment groups showed decrease in body weight and food efficiency in comparison with control group. Blood biochemistry parameters such as TG, TC, LDL, and glucose levels were increased in control group, while AT treatment groups were reduced. Also, the increased levels of ALT and AST were improved by AT extract. We confirmed that the weights of liver, kidney, subcutaneous fat, epididymal fat, kidney leaf fat, and intraabdominal fat were change in LDLr KO mice treated AT extract. In addition, histopathological changes in liver and aorta were similar to normal group.Conclusions : Based on these results, the AT extract is considered to make prevention of atherosclerosis through reduction and functional improvement of the liver and vascular endothelial cells in the body fat accumulation and lipid content in LDLr ko mouse model.

Landscape Ecology Concept, Principles and Its Rlation to Monothematic (e.g. Vegetation) Survey (경관생태학의 개념, 원리 및 식생조사와의 관계)

  • Isaak, S. Zonneveld
    • The Korean Journal of Ecology
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    • v.21 no.4
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    • pp.357-372
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    • 1998
  • Land (scape) ecology is a trans-disciplinary science studying the related systems at the earth surface, in their visual, structural and functional aspects. it serves as an umbrella under which abiotic and biotic sciences, in an integrated way, study the for each relevant land attributes and their interrelations. The spatial aspects of these relations have a special interest. Landscape ecology my have a pure scientific purpose, but usually is executed in an applied context, related to land evaluation for land use and conservation. Depending on the aim and application of the study, one of the land attributes may get special attention. Vegetation mapping may contribute to landscape ecological study but also benefit from it especially in case of reconnaissance surveys. This is because in less detailed surveys of any land attribute, like land form, soil, vegetation, one must necessarily apply landscape ecological principles in the survey methodology, including remote sensing.

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Biodegradabilities of Cotton Fabrics treated with Silicones (실리콘 처리한 면직물의 생분해성)

  • 김보형;박정희;임승순
    • Journal of the Korean Society of Clothing and Textiles
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    • v.28 no.8
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    • pp.1048-1056
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    • 2004
  • Hydrophilicities of finished cotton fabrics were evaluated in respect of moisture regain and wickability. Changes in internal structure were determined using X-ray diffraction and surface changes in degraded samples were observed through a microscopy. Activated sludge test, soil burial test and enzyme hydrolysis were employed to evaluate the biodegradabilities. In addition, correlation analysis was done between biodegradability and the factors affecting biodegradability in each evalution methods. It was shown that hydrophilicities of silicone finished specimens were lower than that of untreated cotton and decreased in a row of PDMS(polydimethyl siloxane : -CH$_3$)>AFS(amino functional siloxane ; -C$_3$H$_{6}$ NHC$_2$H$_4$NH$_2$)>MHPS(methylhydrogen polysiloxane : -H, Cat : (C$_{17}$ H$_{35}$ COO)$_2$Zn) Although, moisture regain of mercerized cotton was higher than those of the others, wickability was shown to be lower. It was represented that crystalinities of cotton fabrics decreased by the silicone treatment. In activated sludge test and soil burial test, biodegradabilities of silicone treated specimens were lower than that of untreated cotton, where specimens of higher biodegradability exhibited higher biodegradability except mercerized ones. The results from enzyme hydrolysis, however, showed somewhat different tendency in that biodegradability was more closely related with the crystallinities of fabrics. It can be thought that enzyme hydrolysis is carried out for short time, physical accessibility becomes important.

Surgical Treatment of Primary Cardiac Tumor -Report of 27 cases - (원발성 심장 종양의 수술적 치료 - 27례 보고-)

  • 박성용;문석환;김치경;조건현;왕영필;이선희;곽문섭;김세화
    • Journal of Chest Surgery
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    • v.31 no.8
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    • pp.787-791
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    • 1998
  • Materials and methods: Between 1979 and 1996, 27 patients with primary cardiac tumor underwent surgery at Catholic University Medical College. Mean age of patient was 45.1${\pm}$3.03 ranging from 21 to 67 years old. Twenty-four cases were myxomas, 2 cases were chondrosarcoma, and remained case was angiosarcoma. Diagnosis was confirmed by echocardiography, cardiac angiography, CT scan, and MRI. The most common site of tumor origin was fossa ovalis limbus area(17cases:63%). A biatrial operative approach was commonly used in 15 cases and the tumor was removed through left atriotomy site. Complete excision of the tumor with a cuff of normal tissue was performed. All heart chambers were carefully explored for evidence of multicentric myxomas or other tumor debris. Most of the patients were improved on postoperative period compared to preoperative NYHA functional class. Results: There was one operative death due to low cardiac output syndrome. Follow up period was 3 months to 17 years. There was 2 late deaths due to local recurrences. Conclusion: complete surgical excion is important for increasing cure rate. Malignancy cannot be ruled out even though preoperative echocardiography suggests benign nature. Chest CT or MRI is effective for further evalution in addition to echocardiography. In suspicious of malignancy, more extensive resection is essential and postoperative chemotheraphy or radiotherapy is useful.

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A Construction and Operation Analysis of Group Management Network about Control Devices based on CIM Level 3 (CIM 계층 3에서 제어 기기들의 그룹 관리 네트워크 구축과 운영 해석)

  • 김정호
    • The Journal of Society for e-Business Studies
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    • v.4 no.1
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    • pp.87-101
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    • 1999
  • To operate the automatic devices of manufacturing process more effectively and to solve the needs of the resource sharing, network technology is applied to the control devices located in common manufacturing zone and operated by connecting them. In this paper, functional standard of the network layers are set as physical and data link layer of IEEE 802.2, 802.4, and VMD application layer and ISO-CIM reference model. Then, they are divided as minimized architecture, designed as group objects which perform group management and service objects which organizes and operates the group. For the stability in this network, this paper measures the variation of data packet length and node number and analyzes the variated value of the waiting time for the network operation. For the method of the analysis, non-exhausted service method are selected, and the arrival rates of the each data packet to the nodes that are assumed to form a Poission distribution. Then, queue model is set as M/G/1, and the analysis equation for waiting time is found. For the evalution of the performance, the length of the data packet varies from 10 bytes to 100 bytes in the operation of the group management network, the variation of the wating time is less than 10 msec. Since the waiting time in this case is less than 10 msec, response time is fast enough. Furthermore, to evaluate the real time processing of the group management network, it shows if the number of nodes is less than 40, and the average arrival time is less than 40 packet/sec, it can perform stable operation even taking the overhead such as software delay time, indicated packet service, and transmissin safety margin.

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Study on function evaluation tools for stroke patients (뇌졸중(腦卒中) 환자(患者)의 기능평가방법(機能評價方法)에 대(對)한 연구(硏究))

  • Ko, Seong-Gyu;Ko, Chang-Nam;Chox, Ki-Ho;Kim, Young-Suk;Bae, Hyung-Sup;Lee, Kyung-Sup
    • The Journal of Korean Medicine
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    • v.17 no.1 s.31
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    • pp.48-83
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    • 1996
  • Our conclusions for function evaluation tools of Stroke patients are as follows. 1. Evaluating tools of Activities of Daily Living, Katz Index, Barthel Index, Modified Barthel Index have high validity and reliability because of ease of measuring, high accuracy, consistency, sensitivity and sufficient stastistics, but they mainly measure motor function except sense, mentation, language, and social conception. Therefore cerebrovascular disease and brain injury in trauma patients with lacked acknowledgement and sensation, we are not able to apply these tools. 2. PULSES Profile is a useful scale for measuring the patient's over-all status, upper and lower limb functions, sensory components, excretary functions, and intellectual and emotional adaptabilities. It is recognized as a good, useful tool to evaluate patient's whole function. 3. Motor Assessment Scale was designed to measure the progress of stroke patients. The scale was supplemented with upper arm function items. We believe that the Motor Assessment Scale could be a useful evaluation tool with inter-rater reliability ,test-retest reliability. 4. The existing evaluation tools, Katz Index, Barthel Index, Modified Barthel Index, PULSES Profile, Motor Assessment Scale, mainly measured the rehabilitational motor function of sequela of cerebrovascular patients. On the other hand CNS & INH stroke scale can measure cerebrovascular disease patient's neurologic deficits and over-all stautus, which are recognition ability, speech status, motor function, sensory function, activities of daily living. Those scales have been recognized as useful tools to measure function of cerebrovascular disease patients and have increased in use. 5. Every function evaluation tool was recognized to have some validity and inter-rater, test-retest reliability in items of each evaluation tool and total scores of each evaluation tools, but it is thought that none of these scales have been fully validated and proved reliable. Therefore afterward, the development of a highly reliable rating system may best be accomplished by a careful comparison of several tools, using the same patients and the same observers in order to choose the most reliable items from each. 6. Ideal evaluation tools must have the following conditions; (1) It should show the objective functional statues at the same time. (2) It should be repeated consecutively to know changed function status. (3) It should be easy to observe the treatment program. (4) It should have the same result with another rater to help rater exchange information with treatment team members. (5) It should be practical and simple. (6) The patient should not suffer from the observer.

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Effect of Concentrated Dangyooja-derived Flavonoids Extract Added to Citrus Beverage on Obesity and Blood Lipids in Rats (당유자 유래 Flavonoids 농축액이 첨가된 감귤 음료의 쥐 비만 및 혈중 지질에 미치는 영향)

  • Choi, Young-Hun;Lee, Young-Jae;Lee, Sun-Yi;Chae, Chi-Won;Park, Suk-Man;Kim, Sang-Suk;An, Hyun-Joo;King, Dale;Han, Chang-Hoon;Hong, Hyun-Ju
    • Horticultural Science & Technology
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    • v.30 no.2
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    • pp.214-219
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    • 2012
  • This study aimed to develop a new type of functional citrus beverage (Citurs-F) containing flavonoids extracted from the young fruits of satsuma mandarin ($Citrus$ $unshiu$) and matured fruits of Jeju native dangyooja ($C.$ $grandis$). We made beverages that contained 30% of satsuma mandarin extract with different percentages of concentrated dangyooja-derived flavonoid extracts. In sensory evalution, the highest response indices of color, taste and aroma were from the beverages based on the 30% young fruit extracts plus 15% (Citrus-F-15) and 20% (Citrus-F-20) flavonoids extract from the dangyooja using the KILO prep. In the changes of body weight after oral administration of the Citrus-F, the rat group with HF diet plus the Citrus-F decreased the body weight compared to the rat group fed only HF diet. This effect was to be continued for 9 weeks until the end of experiment. In the lipid content in blood, the rat group with oral administration of citrus extractions merely tended to resolve it in serum test. However, all the 0.1% Citrus-F-15 and Citrus-F-20 treated rat groups from the beginning or after 5 weeks appeared the lowest lipid contents in the blood. In the cholesterol contents, the rat group feeding the KILO-prep's extraction from the beginning weren't significantly recognized them in the group but the rat group feeding 0.1% Citrus-F-15 acted to reduce in the cholesterol contents from 5 weeks. The results indicated that the Citrus-F-15 with rich flavonoids might be main source alleviating the vascular diseases and obesity in human diet.