Surgical Treatment of Primary Cardiac Tumor -Report of 27 cases -

원발성 심장 종양의 수술적 치료 - 27례 보고-

  • 박성용 (가톨릭대학교 의과대학 흉부외과학교실) ;
  • 문석환 (가톨릭대학교 의과대학 흉부외과학교실) ;
  • 김치경 (가톨릭대학교 의과대학 흉부외과학교실) ;
  • 조건현 (가톨릭대학교 의과대학 흉부외과학교실) ;
  • 왕영필 (가톨릭대학교 의과대학 흉부외과학교실) ;
  • 이선희 (가톨릭대학교 의과대학 흉부외과학교실) ;
  • 곽문섭 (가톨릭대학교 의과대학 흉부외과학교실) ;
  • 김세화 (가톨릭대학교 의과대학 흉부외과학교실)
  • Published : 1998.08.01

Abstract

Materials and methods: Between 1979 and 1996, 27 patients with primary cardiac tumor underwent surgery at Catholic University Medical College. Mean age of patient was 45.1${\pm}$3.03 ranging from 21 to 67 years old. Twenty-four cases were myxomas, 2 cases were chondrosarcoma, and remained case was angiosarcoma. Diagnosis was confirmed by echocardiography, cardiac angiography, CT scan, and MRI. The most common site of tumor origin was fossa ovalis limbus area(17cases:63%). A biatrial operative approach was commonly used in 15 cases and the tumor was removed through left atriotomy site. Complete excision of the tumor with a cuff of normal tissue was performed. All heart chambers were carefully explored for evidence of multicentric myxomas or other tumor debris. Most of the patients were improved on postoperative period compared to preoperative NYHA functional class. Results: There was one operative death due to low cardiac output syndrome. Follow up period was 3 months to 17 years. There was 2 late deaths due to local recurrences. Conclusion: complete surgical excion is important for increasing cure rate. Malignancy cannot be ruled out even though preoperative echocardiography suggests benign nature. Chest CT or MRI is effective for further evalution in addition to echocardiography. In suspicious of malignancy, more extensive resection is essential and postoperative chemotheraphy or radiotherapy is useful.

대상 및 방법: 가톨릭대학교 의과대학 흉부외과학 교실에서는 1979년 부터 1996년까지 27명의 원발성 심장 종양 환자를 수술하였으며, 환자의 연령은 21세부터 67세까지로 평균 45.1세이었다. 술후 병리학적 진단결과 24례는 점액종, 2례는 연골 육종, 1례는 혈관 육종이며, 가장 흔한 술전 증상은 심부전이었다. 진단은 심장초음파로 확진되었고 호발 부위는 난원와였다. 종양 주위를 세심히 관찰후 심방 중격을 포함하여 완전 절제를 시행하였으며 술후 대부분의 환자 에서 증상 호전이 있었다. 결과: 1례에서 수술 직후 저심박출증으로 사망하였고, 2례에서 국소 재발로 인해 만기 사망하였다. 결론: 결론적으로, 수술시 완전 절제가 중요하며 술전 심장 초음파 검사상 양성으로 보일지라도 악성의 가능성을 배제해서는 안되며 CT나 MRI가 진단에 도움이 되며 수술시에 악성이 의심되면 광범위한 절제와 더불어 술후 항암제및 방사선 요법이 도움이 되리라 생각된다.

Keywords

References

  1. Surgery of the chest(6th ed.) Tumors of the Heart Trigt III PV;Sabiston Jr DC;Sabiston JR DC(ed.);Spencer FC(ed.)
  2. 대흉외지 v.22 원발성 심장종양의 수술적 치료 강면식;정경영;조범구;홍승록;소동문
  3. Ann Thorac Surg v.36 Surgical implantations in malignant cardiac disese Poule GV;Meredith JW;Breyer RH;Millis SA
  4. Ann Thorac Surg v.29 Cardiac myxoma Attar S;Lee Y;singleton R;Scherlis L;David R;McLaughlin JS
  5. Ann Surg v.183 Myxoma of the heart: clinical and experimental observations Symbas PN;Hatcher CR Jr;Gravanis MB
  6. Ann Surg v.191 Primary cardiac tumors Silverman NA
  7. Surgery v.111 Atrial myxoma with remote metastasis: Case report and review of the literature Diflo T;Cantelmo NL;Haudenechild CC;Watkins MT
  8. Ann Thorac Surg v.42 Malignant clinical behavior of cardiac myxomas and Attum AA;Johnson GS;Masri Z(et al.)
  9. Br Heart J v.53 Recurring cardiac myxoma Gray IR;Wiliams WG
  10. Chest v.100 DNA analysis of atrial myxoma Kotylo PK;Kennedy JE;Waller BF;Sample RB
  11. Am Heart J v.99 spontaneous cure of infected LA myxoma following embolization Schweiger MJ;Hafer JG;Brown R;Giannelly RE
  12. Am Heart J v.112 Carcinoma of the heart presenting as myocardial infarction Movahead A;Wait J
  13. Chest v.92 Malignant primary cardiac tumors. The Cleveland Clinic experience, 1956-1986 Bear PA;Moodie DS
  14. Ann Thorac Surg v.29 Cardiac myxoma Attar S;Lee Y;Singleton R;Scherlis L;David R;McLaughlin JS
  15. J Thorac Cardiovasc Surg v.93 Primary cardiac neoplasms. early and late result of surgical treatment in 42 patients Dein JR;Frist WH;Stinson EB(et al.)
  16. J Thorac Cardiovasc Surg v.77 Surgical treatment of recurrent primary malignant tumor of the left atrium Gobelman C;AI-Sadir J;Lamberti J(et al.)
  17. Surgery v.61 Surgical management of tumors of the heart Geborde F;Kerth WJ;Hill JD