• 동아시아식생활학회지
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• 제25권5호
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• pp.813-821
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• 2015

Asthma is an increasing global health problem, and novel strategies to prevent or ameliorate the condition are needed. The purpose of the present study was to evaluate the anti-inflammatory and anti-asthma effects of Adenophora triphylla var. japonica extracts. We investigated the molecular mechanism underlying the effects of 80% ethanol extracts (AE) of A. triphylla on lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. AE treatment inhibited pro-inflammatory cytokines such as TNF-${\alpha}$ and IL-6 as well as nitric oxide (NO) production in LPS-stimulated RAW 264.7 cells. In particular, NO and pro-inflammatory cytokine production was suppressed more effectively by aerial parts (AE-A) than roots (AE-R) of A. triphylla. Quantitative RT-PCR assay showed that AE reduced mRNA levels of iNOS and COX-2. We also evaluated the anti-asthmatic effects of AE-A in an ovalbumin (OVA)-induced BALB/c mouse model. AE-A supplementation significantly reduced the amounts of airway eosinophils, IL-4 and IL-13 levels in BALF, and IgE levels in serum as compared with untreated, OVA-induced mice. These results suggest that AE-A can be considered as a therapeutic agent to potentially relieve asthma.

• 한국지역사회생활과학회지
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• 제27권4호
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• pp.779-794
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• 2016

In this study, a functional vegetable garden model is proposed for vegetable gardening users in urban areas to grow different vegetables for various purposes. H vegetable garden user(uneducated) and Y vegetable garden user(educated) urban vegetable gardening users were provided with the functional vegetable garden model and allowed to manage their allocated gardens directly. As the issues raised by the field work and its associated solutions were investigated, the opinions from each group were compared and analyzed. The conclusions are as follows. First, according to the usage survey for vegetable gardening, both groups responded that they had mostly cultivated vegetables. Second, with regard to the kinds of vegetables cultivated in autumn, both groups chose the vegetables required for producing Kimchi. Third, both groups responded that their interest in growing various plants was the major motivation to start gardening. Fourth, regarding the inclusion of flowers and herbs in the functional vegetable garden, more than 90% of the members of both groups responded that the level of the inclusion was appropriate or could be higher.

• 동의생리병리학회지
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• 제23권5호
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• pp.950-957
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• 2009

The purpose of this study was to develop generalized validity evaluation indexes for the Sasang type diagnostic test. As a generalized evaluation index for Sasang type diagnostic test, Generalized Squared Correlation (GC2), Mutual Information (I) and Mutual Information Coefficient (IC) as overall validity index, and Correlation Coefficient (C) and Mutual Information Contribution (ID) as type-specific validity index were suggested and the practicability of these indexes was assessed along with Percentage Correctly Predicted (PCP), adjusted PCP, type-specific sensitivity and type-specific specificity which was proposed previously. The usefulness of the nine validity indexes was examined using previously reported data and three mock Sasang type diagnosis results. We demonstrated here that the PCP is not adequate for the analysis of validity. We also showed that our validity index is recommendable for the comparison and improvement of Sasang type diagnosis. The generalized validity analysis of Sasang type diagnosis can provide a guideline for the development of new Sasang type diagnosis or pattern identification. The working sheet for calculating validity indexes can be acquired at http://www.sasangtypology.org/validity.

• 한국작물학회지
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• 제54권1호
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• pp.24-28
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• 2009

This study was conducted to evaluate the growth characters and yield components of 18 collected sesame cultivars to get basic information on the variation for the sesame breeding using principal component analysis. All characters except days to flowering, days to maturity and 1,000 seed weight showed significantly different. Seed weight per 10 are showed higher coefficient of variance. Capsule bearing stem length and liter weight showed positive correlation with seed yield per 10 are. The principal components analysis grouped the estimated sesame cultivars into four main components which accounted for 83.7% of the total variation at the eigenvalue and its contribution to total variation obtained from principal component analysis. The first principal component ($Z_1$) was applicable to increase plant height, capsule bearing stem length and 1,000-seed weight. The second principal component ($Z_2$) negatively correlated with days to flowering and maturity by which it was applicable to shorten flowering and maturity date of sesame. At the scatter diagram, Yangbaek, Ansan, M1, M2, M4, M7 and M9 were classified as same group, but M10, Yanghuk, Kanghuk, M5, M6, M12 and M13 were classified as different group. This results would be helpful for sesame breeder to understand genetic relationship of some agronomic characters and select promising cross lines for the development of new sesame variety.

• Weed & Turfgrass Science
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• 제2권1호
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• pp.8-14
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• 2013

낙동강 유역 리모델링 농경지의 토양수분 함량별 잡초발생 양상과 군락특성을 분석한 결과 다음과 같은 결과를 얻었다. 조사한 3지역의 pH는 6.3~6.4이었으며 EC는 0.1~0.4 ds $m^{-1}$이었다. 토양수분 함량은 사몰포가 14.6%로 가장 높았으며, 김해가 9.8%, 칠현이 5.6% 순이었다. 또 토양화학성은 사몰포가 유기물 함량은 14.8 g $kg^{-1}$로 김해와 칠현에 비해 높은 경향이었으며, 유효 인산의 함량은 48.0 mg $kg^{-1}$이었다. 리모델링 농경지 및 논뚝에서 발생한 초종은 전체 23과 62종으로 과별로는 국화과가 11종(17.7%)으로 가장 높았으며, 화본과 9종(14.5%), 콩과 8종(12.9%), 방동사니과 7종(11.3%)이었고, 기타 27종(43.6%)이었다. 초종별 우점으로는 사몰포가 피(100%) > 알방동사니(9.0%) > 미국가막사리(3%) > 미국개기장(4.8%) > 한련초(4.4%) 순이었고, 김해는 바랭이(100%) > 미국개기장(49.4%) > 피(48.8%) > 여뀌(27.1%) > 좀명아주(10.2%), 칠현은 미국개기장(90.8%) > 바랭이(66.7%) > 참방동사니(8.6%) > 미국가막사리(7.6%) 순이었다. 잡초 건물중은 사몰포에서 535.4 g $m^{-2}$로 가장 높았고, 그 다음으로 칠현에서 346.2 g $m^{-2}$이었으며, 김해에서는 316.1 g $m^{-2}$이었다. 잡초형태별로는 사몰포가 화본과 > 광엽잡초=방동사니과 순이었으며, 김해와 칠현은 광엽잡초 > 화본과 > 방동사니과 순이었다. 잡초군락의 평균유사성 계수는 18.1%로 토양수분 함량별로 다른 조사 지점간에 81.9%로 초종들의 구성에 차이가 많았다.

• Safe Food
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• 제3권4호
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• pp.12-17
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• 2008

• East Asian mathematical journal
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• 제14권2호
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• pp.299-309
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• 1998

• 대한한방내과학회지
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• 제32권4호
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• pp.584-598
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• 2011

Objectives : Functional dyspepsia is a type of disease characterized by bothersome postprandial fullness, early satiation, epigastric pain and burning without structural gastrointestinal disease. The aim of this study was to analyze the characteristics of functional dyspepsia patients and evaluate changes in symptoms, quality of life, and electrogastrography parameters before and after oriental medical interventions. Methods : We recruited forty-six functional dyspepsia patients who visited gastroenterology clinic in the oriental medicine hospital of Kyung Hee University between November 2009 and February 2011. Patients were assessed for their frequency of dyspepsia (based on short form-Leeds Dyspepsia Questionnaire: SF-LDQ), quality of life (based on functional dyspepsia-related quality of life questionnaire: FD-QoL), gastric motility (based on electrogastrography: EGG) on the first visit. Then, the effect of oriental medical interventions was evaluated using EGG on the second visit. Results : The majority of patients had symptoms of nausea and indigestion. The largest decrease in EGG parameters was found in the indigestion group. The frequency of regurgitation and postprandial EGG power % bradygastria showed a significant correlation. Also, significant correlations were found between some items of FD-QoL and some EGG parameters. Compared to the EGG parameters before oriental medical interventions, some parameters after treatment had positive results, implying the improvement of gastric motility disorder. We also found improvement of EGG parameters in both digestant medicinal group and digestant combined with qi-tonifying medicinal group. Conclusions : The results of this study suggest that clinical application of EGG can be an objective diagnostic tool in functional dyspepsia patients visiting oriental medical hospital.

• 한국식품위생안전성학회지
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• 제39권2호
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• pp.72-82
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• 2024

본 연구는 자일로올리고당의 과학적이고 체계적인 표준화된 시험법을 마련하여 다양한 제형의 제품에 적용하고자 하였다. 최적화된 시험법을 마련하기 위해 초음파 처리 시간, 산 가수분해 시간 및 농도를 검토하여 전처리 방법을 비교 평가하였으며, HPLC-UVD를 이용하여 시료 중의 자일로올리고당을 분석하였다. 분석 시 1-phenyl-3-methyl-5-pyrazoline (PMP)으로 유도체화하고, photo diode array (PDA)가 장착된 high performance liquid chromatography (HPLC) (Nanospace SI-2)를 사용하였으며, 칼럼은 Cadenza C₁₈ (4.6 × 250 mm, 3 ㎛)이었으며, 이동상은 pH를 6.0으로 맞춘 20 mM 인산완충용액과 아세토니트릴을 78:22 비율로 혼합하여 사용하였고, 0.5 mL/min 유속으로 254 nm로 하여 분석하였다. 건강기능식품 등 시험법 마련 표준절차에 관한 가이드라인에 따라 밸리데이션을 수행하고, 표준화된 시험법을 이용하여 유통 중인 건강기능식품 대상 품목에 대해 시험법 적용 여부를 확인하였다. 표준화된 시험법은 자일로올리고당을 함유한 건강기능식품 품질관리에 대한 신뢰성을 더 높일 것으로 본다.

• Molecules and Cells
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• 제21권2호
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• pp.284-293
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• 2006

Even though Ac/Ds gene-tagging systems have been established in many higher plants, maize is the only major plant in which short-distance transposition of Ac/Ds has been utilized to probe gene function. This study was performed to evaluate the efficiency of obtaining new alleles and functional revertants from Ds insertion loci in rice. By analyzing 1,580 plants and the progeny of selected lines, the insertion sites and orientations of Ds elements within 16 new heritable alleles of three rice loci were identified and characterized. Intragenic transposition was detected in both directions from the original insertion sites. The closest interval was 35 bp. Three of the alleles had two Ds elements in cis configuration in the same transcription units. We also analyzed the excision footprints of intragenic and extragenic transpositions in Ds-inserted alleles at 5 loci. The 134 footprints obtained from different plants revealed predominant patterns. Ds excision at each locus left a predominant footprint at frequencies of 30-75%. Overall, 66% of the footprints were 7-bp additions. In addition, 16% of the excisions left 0-, 3-, 6-, and 9-bp additions with the potential of conserving reading frame.