• Journal of the East Asian Society of Dietary Life
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• v.25 no.5
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• pp.813-821
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• 2015

Asthma is an increasing global health problem, and novel strategies to prevent or ameliorate the condition are needed. The purpose of the present study was to evaluate the anti-inflammatory and anti-asthma effects of Adenophora triphylla var. japonica extracts. We investigated the molecular mechanism underlying the effects of 80% ethanol extracts (AE) of A. triphylla on lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. AE treatment inhibited pro-inflammatory cytokines such as TNF-${\alpha}$ and IL-6 as well as nitric oxide (NO) production in LPS-stimulated RAW 264.7 cells. In particular, NO and pro-inflammatory cytokine production was suppressed more effectively by aerial parts (AE-A) than roots (AE-R) of A. triphylla. Quantitative RT-PCR assay showed that AE reduced mRNA levels of iNOS and COX-2. We also evaluated the anti-asthmatic effects of AE-A in an ovalbumin (OVA)-induced BALB/c mouse model. AE-A supplementation significantly reduced the amounts of airway eosinophils, IL-4 and IL-13 levels in BALF, and IgE levels in serum as compared with untreated, OVA-induced mice. These results suggest that AE-A can be considered as a therapeutic agent to potentially relieve asthma.

• The Korean Journal of Community Living Science
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• v.27 no.4
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• pp.779-794
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• 2016

In this study, a functional vegetable garden model is proposed for vegetable gardening users in urban areas to grow different vegetables for various purposes. H vegetable garden user(uneducated) and Y vegetable garden user(educated) urban vegetable gardening users were provided with the functional vegetable garden model and allowed to manage their allocated gardens directly. As the issues raised by the field work and its associated solutions were investigated, the opinions from each group were compared and analyzed. The conclusions are as follows. First, according to the usage survey for vegetable gardening, both groups responded that they had mostly cultivated vegetables. Second, with regard to the kinds of vegetables cultivated in autumn, both groups chose the vegetables required for producing Kimchi. Third, both groups responded that their interest in growing various plants was the major motivation to start gardening. Fourth, regarding the inclusion of flowers and herbs in the functional vegetable garden, more than 90% of the members of both groups responded that the level of the inclusion was appropriate or could be higher.

• Journal of Physiology & Pathology in Korean Medicine
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• v.23 no.5
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• pp.950-957
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• 2009

The purpose of this study was to develop generalized validity evaluation indexes for the Sasang type diagnostic test. As a generalized evaluation index for Sasang type diagnostic test, Generalized Squared Correlation (GC2), Mutual Information (I) and Mutual Information Coefficient (IC) as overall validity index, and Correlation Coefficient (C) and Mutual Information Contribution (ID) as type-specific validity index were suggested and the practicability of these indexes was assessed along with Percentage Correctly Predicted (PCP), adjusted PCP, type-specific sensitivity and type-specific specificity which was proposed previously. The usefulness of the nine validity indexes was examined using previously reported data and three mock Sasang type diagnosis results. We demonstrated here that the PCP is not adequate for the analysis of validity. We also showed that our validity index is recommendable for the comparison and improvement of Sasang type diagnosis. The generalized validity analysis of Sasang type diagnosis can provide a guideline for the development of new Sasang type diagnosis or pattern identification. The working sheet for calculating validity indexes can be acquired at http://www.sasangtypology.org/validity.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.54 no.1
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• pp.24-28
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• 2009

This study was conducted to evaluate the growth characters and yield components of 18 collected sesame cultivars to get basic information on the variation for the sesame breeding using principal component analysis. All characters except days to flowering, days to maturity and 1,000 seed weight showed significantly different. Seed weight per 10 are showed higher coefficient of variance. Capsule bearing stem length and liter weight showed positive correlation with seed yield per 10 are. The principal components analysis grouped the estimated sesame cultivars into four main components which accounted for 83.7% of the total variation at the eigenvalue and its contribution to total variation obtained from principal component analysis. The first principal component ($Z_1$) was applicable to increase plant height, capsule bearing stem length and 1,000-seed weight. The second principal component ($Z_2$) negatively correlated with days to flowering and maturity by which it was applicable to shorten flowering and maturity date of sesame. At the scatter diagram, Yangbaek, Ansan, M1, M2, M4, M7 and M9 were classified as same group, but M10, Yanghuk, Kanghuk, M5, M6, M12 and M13 were classified as different group. This results would be helpful for sesame breeder to understand genetic relationship of some agronomic characters and select promising cross lines for the development of new sesame variety.

• Weed & Turfgrass Science
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• v.2 no.1
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• pp.8-14
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• 2013

Collection of weeds were done in 3 remodeled paddy fields located in different districts with different soil moisture conditions such as Samolpo district (14.6%), Gimhae (9.8%) and Chilhyun (5.6%). Remodeled paddy fields composed of 62 plant species belonging to 23 families. Among 23 families, Compositae was the largest family with 11 species belonged to (17.7%) followed by Poaceae with 9 species (14.5%), Leguminosae with 8 species (12.9%), Cyperaceae with 7 species (11.3%), and Polygonaceae with 5 species (8.1%). Summed dominance ratio of each species based on number, coverage, frequency, and plant height in Samolpo district was Echinochloa oryzoides (100%) > Cyperus difformis (9.0%) > Bidens frondosa (5.3%) > Panicum dichotomiflorum (4.8%) > Eclipta prostrata (4.4%). In Gimhae; Digitaria ciliaris (100%) > Panicum dichotomiflorum (49.4%) > Echinochloa oryzoides (48.8%) > Persicaria hydropiper (27.1%) > Chenopodium ficifolium (10.2%), and in Chilhyun were Panicum dichotomiflorum (90.8%) > Digitaria ciliaris (66.7%) > Cyperus iria (8.6%) > Bidens frondosa (7.6%). Total dry weight of weeds recorded was 535.4 g $m^{-2}$, 316.1 g $m^{-2}$ and 346.2 g $m^{-2}$ in Samolpo, Gimhae and Chilhyun districts, respectively. Simpson's index was calculated to 0.09~0.28, which showed that weed occurrence in remodeled paddy fields with different soil moistures varied.

• Safe Food
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• v.3 no.4
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• pp.12-17
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• 2008

• East Asian mathematical journal
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• v.14 no.2
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• pp.299-309
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• 1998

• The Journal of Internal Korean Medicine
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• v.32 no.4
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• pp.584-598
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• 2011

Objectives : Functional dyspepsia is a type of disease characterized by bothersome postprandial fullness, early satiation, epigastric pain and burning without structural gastrointestinal disease. The aim of this study was to analyze the characteristics of functional dyspepsia patients and evaluate changes in symptoms, quality of life, and electrogastrography parameters before and after oriental medical interventions. Methods : We recruited forty-six functional dyspepsia patients who visited gastroenterology clinic in the oriental medicine hospital of Kyung Hee University between November 2009 and February 2011. Patients were assessed for their frequency of dyspepsia (based on short form-Leeds Dyspepsia Questionnaire: SF-LDQ), quality of life (based on functional dyspepsia-related quality of life questionnaire: FD-QoL), gastric motility (based on electrogastrography: EGG) on the first visit. Then, the effect of oriental medical interventions was evaluated using EGG on the second visit. Results : The majority of patients had symptoms of nausea and indigestion. The largest decrease in EGG parameters was found in the indigestion group. The frequency of regurgitation and postprandial EGG power % bradygastria showed a significant correlation. Also, significant correlations were found between some items of FD-QoL and some EGG parameters. Compared to the EGG parameters before oriental medical interventions, some parameters after treatment had positive results, implying the improvement of gastric motility disorder. We also found improvement of EGG parameters in both digestant medicinal group and digestant combined with qi-tonifying medicinal group. Conclusions : The results of this study suggest that clinical application of EGG can be an objective diagnostic tool in functional dyspepsia patients visiting oriental medical hospital.

• Journal of Food Hygiene and Safety
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• v.39 no.2
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• pp.72-82
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• 2024

This study aimed to develop a scientifically and systematically standardized xylooligosaccharide analytical method that can be applied to products with various formulations. The analysis method was conducted using HPLC with Cadenza C₁₈ column, involving pre-column derivatization with 1-phenyl-3-methyl-5-pyrazoline (PMP) and UV detection at 254 nm. The xylooligosaccharide content was analyzed by converting xylooligosaccharide into xylose through acid hydrolysis. The pre-treated methods were compared and evaluated by varying sonication time, acid hydrolysis time, and concentration. Optimal equipment conditions were achieved with a mobile phase consisting of 20 mM potassium phosphate buffer (pH 6)-acetonitrile (78:22, v/v) through isocratic elution at a flow rate of 0.5 mL/min (254 nm). Furthermore, we validated the advanced standardized analysis method to support the suitability of the proposed analytical procedure such as specificity, linearity, detection limits (LOD), quantitative limits (LOQ), accuracy, and precision. The standardized analysis method is now in use for monitoring relevant health-functional food products available in the market. Our results have demonstrated that the standardized analysis method is expected to enhance the reliability of quality control for healthy functional foods containing xylooligosaccharide.

• Molecules and Cells
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• v.21 no.2
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• pp.284-293
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• 2006

Even though Ac/Ds gene-tagging systems have been established in many higher plants, maize is the only major plant in which short-distance transposition of Ac/Ds has been utilized to probe gene function. This study was performed to evaluate the efficiency of obtaining new alleles and functional revertants from Ds insertion loci in rice. By analyzing 1,580 plants and the progeny of selected lines, the insertion sites and orientations of Ds elements within 16 new heritable alleles of three rice loci were identified and characterized. Intragenic transposition was detected in both directions from the original insertion sites. The closest interval was 35 bp. Three of the alleles had two Ds elements in cis configuration in the same transcription units. We also analyzed the excision footprints of intragenic and extragenic transpositions in Ds-inserted alleles at 5 loci. The 134 footprints obtained from different plants revealed predominant patterns. Ds excision at each locus left a predominant footprint at frequencies of 30-75%. Overall, 66% of the footprints were 7-bp additions. In addition, 16% of the excisions left 0-, 3-, 6-, and 9-bp additions with the potential of conserving reading frame.