• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2013년도 추계학술대회
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• pp.1055-1057
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• 2013

최근 사용되는 유무선 공유기는 하나의 IP를 여러 대의 컴퓨터가 인터넷에 접속할 수 있도록 해주는 기능을 한다. 웹 서버나 프린트 서버, 웹 하드, P2P의 기능을 하기 위해서는 PC나 서버에서 별도의 설정 또는 구축 작업을 통해서만 가능하였다. 본 논문에서는 OpenWRT 공유기 활용한 네트워크 설정과 동시에 방화벽 및 다양한 정책 설정을 기본으로 한 보안이 강화된 서버를 통해 안정적이며 안전한 멀티미디어 서비스 및 인터넷 전화를 제공함으로써, 모바일 APP 및 PC프로그램을 통해 서비스를 제공받을 수 있는 다기능의 유무선 공유기를 통해 웹서버를 구축한다.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 2007년도 정기 학술대회 논문집
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• pp.145-150
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• 2007

The spacer grid set is a component in the nuclear fuel assembly. The set supports the fuel rods saftely. Therefore, the spacer gl1d set should have sufficient strength for the external impact forces. The fretting wear occurs between the spring of the fuel rod and the spacer grid due to tile flow-induced vibration. The conceptual design of the spacer grid set is performed based on the Independence Axiom of axiomatic design. Two functional requirements are defined and corresponding design parameters are selected. The overall flow of the design is defined according to the application of axiomatic design. The design for the impact load is carried out by using nonlinear dynamic analysis to determine the length of the dimple. Topology optimization is carried out to determine a new configuration of the spring. The fretting wear is reduced by shape optimization using the homology theory. In the design to reduce the fretting wear, the deformed shape of the spring should be the same as that of the fuel rod. This condition is transformed to a function and considered as a constraint in the shape optimization process. The fretting wear is expected to be reduced due to the homology constraint. The objective function is minimizing the maximum stress to allow a slight plastic deformation. Shape optimization results are confirmed through nonlinear static analysis because the contact area becomes wider.

• The Korean Journal of Physiology and Pharmacology
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• 제7권1호
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• pp.15-23
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• 2003

Cellular redox state is known to be perturbed during ischemia and that $Ca^{2+}$ and $K^2$ channels have been shown to have functional thiol groups. In this study, the properties of thiol redox modulation of the ATP-sensitive $K^2$ ($K_{ATP}$) channel were examined in rabbit ventricular myocytes. Rabbit ventricular myocytes were isolated using a Langendorff column for coronary perfusion and collagenase. Single-channel currents were measured in excised membrane patch configuration of patch-clamp technique. The thiol oxidizing agent 5,5'-dithio-bis-(2-nitro-benzoic acid) (DTNB) inhibited the channel activity, and the inhibitory effect of DTNB was reversed by dithiothreitol (disulfide reducing agent; DTT). DTT itself did not have any effect on the channel activity. However, in the patches excised from the metabolically compromised cells, DTT increased the channel activity. DTT had no effect on the inhibitory action by ATP, showing that thiol oxidation was not involved in the blocking mechanism of ATP. There were no statistical difference in the single channel conductance for the oxidized and reduced states of the channel. Analysis of the open and closed time distributions showed that DTNB had no effect on open and closed time distributions shorter than 4 ms. On the other hand, DTNB decreased the life time of bursts and increased the interburst interval. N-ethylmaleimide (NEM), a substance that reacts with thiol groups of cystein residues in proteins, induced irreversible closure of the channel. The thiol oxidizing agents (DTNB, NEM) inhibited of the $K_{ATP}$ channel only, when added to the cytoplasmic side. The results suggested that metabolism-induced changes in the thiol redox can also modulate $K_{ATP}$ channel activity and that a modulatory site of thiol redox may be located on the cytoplasmic side of the $K_{ATP}$ channel in rabbit ventricular myocytes.

• The Korean Journal of Physiology and Pharmacology
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• 제7권1호
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• pp.25-28
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• 2003

Ion channel inhibitors are widely used for pharmacological discrimination between the different channel types as well as for determination of their functional role. In the present study, we tested the hypothesis that 4-aminopyridine (4-AP) could affect the large conductance $Ca^{2+}$-activated $K^+$ channel ($BK_{Ca}$) currents using perforated-patch or cell-attached configuration of patch-clamp technique in the rabbit pulmonary arterial smooth muscle. Application of 4-AP reversibly inhibited the spontaneous transient outward currents (STOCs). The reversal potential and the sensitivity to charybdotoxin indicated that the STOCs were due to the activation of $BK_{Ca}$. The $BK_{Ca}$ currents were recorded in single channel resolution under the cell-attached mode of patch-clamp technique for minimal perturbation of intracellular environment. Application of 4-AP also inhibited the single $BK_{Ca}$ currents reversibly and dose-dependently. The membrane potential of rabbit pulmonary arterial smooth muscle cells showed spontaneous transient hyperpolarizations (STHPs), presumably due to the STOC activities, which was also inhibited by 4-AP. These results suggest that 4-AP can inhibit $BK_{Ca}$ currentsin the intact rabbit vascular smooth muscle. The use of 4-AP as a selective voltage-dependent $K^+$ (KV) channel blocker in vascular smooth muscle, therefore, must be reevaluated.

• 복식
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• 제60권10호
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• pp.133-145
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• 2010

The study used four basic formats classified based on the four principles on costumes discussed in the paper 'Human Beings and Arts Phenomena' by Oskar Schlemmer who studied the relationships between stage space and the human body as an analysis tool with regard to analyses on the abstraction of human body in contemporary dance costume. Abstraction of human body expressed in costume for contemporary dance is as follows: Expansions caused by unclear boundary between spaces and costumes, and the principles of three-dimensional abstract spaces based on a geometric cube change heads, trunks, arms and legs to achieve expansions. Similar mechanical shape is a type of shape made in a succession of functional principles of human body in relationships with spaces. As mechanical mechanism is added to the geometric transformation of a specific part of human body, mechanicalness is contained in it. Motion organisms are geometric simplification of moving traces in a space based on conversion into mechanical organisms based on principles of motion, and as mechanical rotation, consecutive speed caused by refraction and directionality are suggested, mobility is achieved. Immaterial shape is based on change into a metaphysical form, and it is converted into animals, plants or a third life that symbolize body parts. It has metaphysical significance in each body part and extends sensibility. As a result of the study, development into abstract succession and a techno art mode has been confirmed. Combination of geometric cubic figures with the organic human body and configuration of the human body pursued by Oskar Schlemmer's geometric abstraction through the proactive accommodation of mechanical aesthetics has been succeeded and expressed in the contemporary dance costumes.

• 한국생산제조학회지
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• 제25권4호
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• pp.266-270
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• 2016

We present a useful and practical manufacturing technique that enables the structural conversion of delicate as-grown nanostructures to more beneficial and robust thin-film frameworks through controlled mechanical rolling. Functional nanostructures such as carbon nanotubes grown through chemical vapor deposition in a vertically aligned and very loosely packed manner, and thus difficult to manipulate for subsequent uses, can be prepared in an array of thin blades by patterning the growth catalyst layer. They can then be toppled as dominos through precisely controlled mechanical rolling. The nanostructures formulated to horizontally aligned thin films are much more favorable for device applications typically based on thin-film configuration. The proposed technique may broaden the functionality and applicability of as-grown nanostructures by converting them into thin-film frameworks that are easier to handle and more durable and favorable for fabricating thin-film devices for electronics, sensors, and other applications.

• 한국문헌정보학회지
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• 제49권2호
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• pp.135-168
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• 2015

본 연구의 목적은 초 중 고등학교 수업 자료의 재사용과 공유를 효율적으로 지원하기 위한 큐레이션 시스템의 기능을 도출하는 것이다. 수업 자료의 활용현황을 조사한 면담을 통해 현장 교사들이 수업 자료를 자주 사용하고 있다는 것과 수업 자료 생산 매체 및 수업 자료 사용 목적이 초등학교와 중 고등학교 간 차이가 있다는 것을 확인하였다. 설문 조사를 통해 재사용과 공유를 위한 큐레이션 시스템의 요구사항을 도출하였다. 큐레이션 전략에 관한 기존의 연구를 조사하여 효과적인 시스템 운영을 위한 정책, 디자인, 표준 및 도구에 대한 전략을 식별하였다. 이상의 조사 결과를 반영하여 설계한 큐레이션 시스템의 업무와 기능은 다음과 같다. 개인 작업 공간에서 구현되어야하는 업무는 인증, 환경설정, 등록, 보관, 편집을 통한 재사용이다. 공유를 위한 공동 작업 공간으로 구현되어야하는 업무는 접수, 저장, 동료 평가, 접근이다.

• 한국통신학회논문지
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• 제37C권12호
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• pp.1222-1229
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• 2012

가정 및 빌딩에서의 에너지 소비 절감 및 효율 향상을 위한 에너지 절감 시스템(ESS)의 새로운 구조와 기능 요구사항을 정의하는 신규 국제표준 제안서를 2009년에 IEC TC 100에 제안하고 최종 IEC PT 62654라는 신규 프로젝트로 채택이 되었다. 최근 표준 발간을 위한 최종 투표에서 만장일치로 통과함에 따라 2012년 8월 IEC TS 62654 규격이 발간되었다. 표준의 검증을 위해 ESS 서버, ESS 클라이언트, 휴대용 ESS 터미널로 구성되는 ESS 시스템의 프로토타입을 표준화 과정과 병행하여 구현하였으며, 또한 ESS 서버와 클라이언트간 통신을 위한 EPCM 프로토콜을 구현하였다. EPCM 프로토콜은 ESS 네트워크의 자동 구성, 전력 소비 모니터링, 원격 전원 제어 및 지능적인 에너지 절감 서비스를 위한 부가 기능들을 지원한다.

• Genomics & Informatics
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• 제2권1호
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• pp.45-52
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• 2004

The self-splicing group I intron from Tetrahymena thermophila has been demonstrated to perform splicing reaction with its substrate RNA in the trans configuration. In this study, we explored the potential use of the trans-splicing group I ribozymes to replace a specific RNA with a new RNA that exerts any new function we want to introduce. We have chosen thymidine phosphorylase (TP) RNA as a target RNA that is known as a valid cancer prognostic factor. Cancer-specific expression of TP RNA was first evaluated with RT-PCR analysis of RNA from patients with gastric cancer. We determined next which regions of the TP RNA are accessible to ribozymes by employing an RNA mapping strategy, and found that the leader sequences upstream of the AUG start codon appeared to be particularly accessible. A specific ribozyme recognizing the most accessible sequence in the TP RNA with firefly luciferase transcript as a 3' exon was then developed. The specific trans-splicing ribozyme transferred an intended 3' exon tag sequence onto the targeted TP transcripts, resulting in a more than two fold induction of the reporter activity in the presence of TP RNA in mammalian cells, compared to the absence of the target RNA. These results suggest that the Tetrahymena ribozyme can be a potent anti-cancer agent to modify TP RNAs in tumors with a new RNA harboring anti-cancer activity.

• 정보처리학회논문지C
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• 제8C권6호
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• pp.865-874
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• 2001

본 논문에서는 Home Phoneline Neworking Aliance(Home PNA) 장치에 연결된 많은 가입자들로부터 야기될수 있는 대역폭 서비스 불균형 현상을 해결하고 이 장비를 이용하는 가입자들을 관리하기 위한 웹 기반 Home PNA 장치 관리시스템을 구현하였다. Simple-Net-work Managment Protocol(SNMP) 를 탑대한 Home PNA장치를 관리하기 위해서 관리항목을 Muti Dewling Unit(MDU) 장비으 Management Information Base(MB)로 부터 추출한 MIB 오브젝트를 이용하여 시스템관리, 포트관리, 성능관리, 장애관리로 분류하였다. 시스템관리는 개별 MDU 장비에 대해 구성정보를 제공하고, 포트관리는 현재 가입되어 있는 가입자에 대한 현황정보를 제공하고 비인가 가입자에 대한 필터링을 수행한다 그리고 성능관리는 트렁크 라인과 가입자 라인의 트랙픽 정보를 제공한다. 마지막으로 장애관리는 예외 상황에 대한 장애로그 및 trap 메시지를 제공한다. 구현된 시스템의 운영성을 시험하기 위하여 실제 네트워크에서 그 동작성을 검증하였다.