• International Journal of Naval Architecture and Ocean Engineering
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• v.3 no.1
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• pp.86-94
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• 2011

This paper compares frequency domain and time domain predictions from the ShipMo3D ship motion library with observed motions from model tests and sea trials. ShipMo3D evaluates hull radiation and diffraction forces using the frequency domain Green function for zero forward speed, which is a suitable approach for ships travelling at moderate speed (e.g., Froude numbers up to 0.4). Numerical predictions give generally good agreement with experiments. Frequency domain and linear time domain predictions are almost identical. Evaluation of nonlinear buoyancy and incident wave forces using the instantaneous wetted hull surface gives no improvement in numerical predictions. Consistent prediction of roll motions remains a challenge for seakeeping codes due to the associated viscous effects.

• Interdisciplinary Bio Central
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• v.1 no.2
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• pp.8.1-8.6
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• 2009

Introduction: It is a challenge to design a protein score function which stabilizes the native structures of many proteins simultaneously. The coarse-grained description of proteins to construct the pairwise-contact score function usually ignores the backbone directionality of protein structures. We propose a new two-body score function which stabilizes all native states of 1,006 proteins simultaneously. This two-body score function differs from the usual pairwise-contact functions in that it considers two adjacent amino acids at two ends of each peptide bond with the backbone directionality from the N-terminal to the C-terminal. The score is a corresponding propensity for a directional alignment of two adjacent amino acids with their local environments. Results and Discussion: We show that the construction of a directional adjacency-score function was achieved using 1,006 training proteins with the sequence homology less than 30%, which include all representatives of different protein classes. After parameterizing the local environments of amino acids into 9 categories depending on three secondary structures and three kinds of hydrophobicity of amino acids, the 32,400 adjacency-scores of amino acids could be determined by the perceptron learning and the protein threading. These could stabilize simultaneously all native folds of 1,006 training proteins. When these parameters are tested on the new distinct 382 proteins with the sequence homology less than 90%, 371 (97.1%) proteins could recognize their native folds. We also showed using these parameters that the retro sequence of the SH3 domain, the B domain of Staphylococcal protein A, and the B1 domain of Streptococcal protein G could not be stabilized to fold, which agrees with the experimental evidence.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.42 no.8 s.338
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• pp.41-46
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• 2005

Microstrip open-end and linear resonator are analyzed by method of moment (MoM) taking the entire-domain current distribution, found in literature, along the transverse direction of microstrip line. A transverse correlation function which incorporates permittivity, thickness and width of the line is derived. Numerical examples are investigated and compared with the available other data and methods in order to give the validity of the proposed method. It is found that the proposed method can generate more accurate results than the conventional methods.

• Honam Mathematical Journal
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• v.29 no.4
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• pp.701-721
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• 2007

Recently, a new singular function(NSF) method was posed to get accurate numerical solution on quasi-uniform grids for two-dimensional Poisson and interface problems with domain singularities by the first author and his coworkers. Using the singular function representation of the solution, dual singular functions, and an extraction formula for stress intensity factors, the method poses a weak problem whose solution is in $H^2({\Omega})$ or $H^2({\Omega}_i)$. In this paper, we show that the singular functions, which are not in $H^2({\Omega})$, also satisfy the integration by parts and note that this fact suggests the possibility of different choice of the weak formulations. We show that the original choice of weak formulation of NSF method is critical.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.37 no.2
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• pp.8-15
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• 2000

This study presents an H$_{\infty}$ optimal controller synthesis by the frequency domain analysis of weighting function. The main purpose of our study is to visualize weighting function domains and open loop transfer function domains that satisfy robustness and performance. Also we aim to simplify the iterative algorithm for H$\infty$ optimal controller synthesis. We report that the designed regulator by the proposed method in this paper satisfies the desired specifications and performance in spite of the plant uncertainty variation at any operating point.

• Transactions of the Korean Society of Automotive Engineers
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• v.5 no.1
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• pp.136-145
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• 1997

To analyzed ride quality and to predict durability in vehicle dynamics, it is essential to describe a road surface profile precisely. This paper presents a technique to generate road surface profiles in a spatial domain by using a power spectral density function. A single track power spectral density function is proposed to describe a road surface profile, which is also applicable for multi-track vehicle response analysis, The derived road surfaces are compared to ISO(International Organization for Standardization) standards and classifications, proposed by the MIRA(Motor Industry Research Association). The methodology in this paper is also proposed to generate road roughness description with a limited external data. A small amount of external curve data is combined with an internal PSD function to generate road surface roughness in a spatial domain.

• Journal of the Korean Institute of Telematics and Electronics B
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• v.29B no.1
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• pp.94-101
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• 1992

The multilayer perceptron, trained by the error back-propagation learning rule, has been known as a mapping network which can represent arbitrary functions. However depending on the complexity of a function and the initial weights of the multilayer perceptron, the error back-propagation learning may fall into a local minimum or a flat area which may require a long learning time or lead to unsuccessful learning. To solve such difficulties in training the multilayer perceptron by standard error back-propagation learning rule, the paper proposes a learning method which progressively enlarges the learning domain from a small area to the entire region. The proposed method is devised from the investigation on the roles of hidden nodes and connection weights in the multilayer perceptron which approximates a function of one variable. The validity of the proposed method was illustrated through simulations for a function of one variable and a function of two variable with many extremal points.

• Journal of Life Science
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• v.14 no.6 s.67
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• pp.991-996
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• 2004

This paper deals with an integrated system that facilitates researchers to do motif and domain search effectively and systematically. The system we developed is constructed on the basis of the integration of various resources related to motif, domain, and protein family. Those resources that can be classified into databases and search programs are dispersed to be available in Internet. In order to develop this system, we extracted core contents of diverse databases, which are required to analyze the protein function in terms of motifs or domains, to construct local databases and installed motif or domain search programs on our server, which corresponding database has as its own search program. Diverse utilities and CGI (Common Gateway Interface) programs make the databases and the search programs interlocked and web-based graphical user interfaces integrate all the components of our system. Employing our integrated system, end-users can receive its one-stop service to do protein function analysis systematically and effectively, without surfing many sites in Internet and wasting time over integrating search results.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.35 no.1A
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• pp.71-79
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• 2010

The algorithm of multiple channel signal processing requires the flexibility of variable frequency band, efficient allocation of transmission power, and flexible frequency band reallocation to satisfy various service types which requires different transmission rates and frequency band. This paper proposes an improved multiple channel signal processing for converting the frequency band of multiple carrier signals efficiently using a window function and DFT in the time domain. In contrast to the previous algorithm of multiple-channel signal processing performing band-pass signal processing in the frequency domain, the proposed algorithm is a method of block signal processing using a window function in the time domain. In addition, the complexity of proposed algorithm of the window function is lower than that of the previous algorithm performing signal processing in the frequency domain, and it performs the frequency band transform efficiently. The computer simulation result shows that the perfect reconstruction of output signal and the flexible frequency band reallocation is performed efficiently by the proposed algorithm.

• BMB Reports
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• v.52 no.12
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• pp.700-705
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• 2019

The bacterial effector protein RavZ is secreted by the intracellular pathogen Legionella pneumophila and inhibits host autophagy through an irreversible deconjugation of mammalian ATG8 (mATG8) proteins from autophagosome membranes. However, the roles of the LC3 interacting region (LIR) motifs in RavZ function remain unclear. In this study, we show that a membrane-targeting (MT) domain or the LIR motifs of RavZ play major or minor roles in RavZ function. A RavZ mutant that does not bind to mATG8 delipidated all forms of mATG8-phosphatidylethanolamine (PE) as efficiently as did wild-type RavZ. However, a RavZ mutant with a deletion of the MT domain selectively delipidated mATG8-PE less efficiently than did wild-type RavZ. Taken together, our results suggest that the effects of LIR motifs and the MT domain on RavZ activity are complementary and work through independent pathways.