• Title/Summary/Keyword: Function Domain

Search Result 2,064, Processing Time 0.032 seconds

Exploring Cross-function Domain Interaction Map

  • Li, Xiao-Li;Tan, Soon-Heng;Ng, See-Kiong
    • Proceedings of the Korean Society for Bioinformatics Conference
    • /
    • 2005.09a
    • /
    • pp.431-436
    • /
    • 2005
  • Living cells are sustained not by individual activities but rather by coordinated summative efforts of different biological functional modules. While recent research works have focused largely on finding individual functional modules, this paper attempts to explore the connections or relationships between different cellular functions through cross-function domain interaction maps. Exploring such a domain interaction map can help understand the underlying inter-function communication mechanisms. To construct a cross-function domain interaction map from existing genome-wide protein-protein interaction datasets, we propose a two-step procedure. First, we infer conserved domain-domain interactions from genome-wide protein-protein interactions of yeast, worm and fly. We then build a cross-function domain interaction map that shows the connections of different functions through various conserved domain interactions. The domain interaction maps reveal that conserved domain-domain interactions can be found in most detected cross-functional relationships and a f9w domains play pivotal roles in these relationships. Another important discovery in the paper is that conserved domains correspond to highly connected protein hubs that connect different functional modules together.

  • PDF

Local structural alignment and classification of TIM barrel domains

  • Keum, Chang-Won;Kim, Ji-Hong;Jung, Jong-Sun
    • Bioinformatics and Biosystems
    • /
    • v.1 no.2
    • /
    • pp.123-127
    • /
    • 2006
  • TIM barrel domain is widely studied since it is one of most common structure and mediates diverse function maintaining overall structure. TIM barrel domain's function is determined by local structural environment at the C-terminal end of barrel structure. We classified TIM barrel domains by local structural alignment tool, LSHEBA, to understand characteristics of TIM barrel domain's functionalvariation. TIM barrel domains classified as the same cluster share common structure, function and ligands. Over 80% of TIM barrels in clusters share exactly the same catalytic function. Comparing clustering result with that of SCOP, we found that it's important to know local structural environment of TIM barrel domains rather than overallstructure to understand specific structural detail of TIM barrel function. Non TIM barrel domains were associated to make different domain combination to form a different function. The relationship between domain combination, we suggested expected evolutional history. We finally analyzed the characteristics of amino acids around ligand interface.

  • PDF

Shape Reconstruction from Unorganized Cloud of Points using Adaptive Domain Decomposition Method (적응적 영역분할법을 이용한 임의의 점군으로부터의 형상 재구성)

  • Yoo Dong-Jin
    • Journal of the Korean Society for Precision Engineering
    • /
    • v.23 no.8 s.185
    • /
    • pp.89-99
    • /
    • 2006
  • In this paper a new shape reconstruction method that allows us to construct surface models from very large sets of points is presented. In this method the global domain of interest is divided into smaller domains where the problem can be solved locally. These local solutions of subdivided domains are blended together according to weighting coefficients to obtain a global solution using partition of unity function. The suggested approach gives us considerable flexibility in the choice of local shape functions which depend on the local shape complexity and desired accuracy. At each domain, a quadratic polynomial function is created that fits the points in the domain. If the approximation is not accurate enough, other higher order functions including cubic polynomial function and RBF(Radial Basis Function) are used. This adaptive selection of local shape functions offers robust and efficient solution to a great variety of shape reconstruction problems.

Filling Holes in Large Polygon Models Using an Implicit Surface Scheme and the Domain Decomposition Method

  • Yoo, Dong-Jin
    • International Journal of Precision Engineering and Manufacturing
    • /
    • v.8 no.1
    • /
    • pp.3-10
    • /
    • 2007
  • A new approach based on implicit surface interpolation combined with domain decomposition is proposed for filling complex-shaped holes in a large polygon model, A surface was constructed by creating a smooth implicit surface from an incomplete polygon model through which the actual surface would pass. The implicit surface was defined by a radial basis function, which is a continuous scalar-value function over the domain $R^{3}$. The generated surface consisted of the set of all points at which this scalar function is zero. It was created by placing zero-valued constraints at the vertices of the polygon model. The well-known domain decomposition method was used to treat the large polygon model. The global domain of interest was divided into smaller domains in which the problem could be solved locally. The LU decomposition method was used to solve the set of small local problems; the local solutions were then combined using weighting coefficients to obtain a global solution. The validity of this new approach was demonstrated by using it to fill various holes in large and complex polygon models with arbitrary topologies.

FINDING THE OPTIMUM DOMAIN OF A NONLINEAR WAVE OPTIMAL CONTROL SYSTEM BY MEASURES

  • J., A.Fakharzadeh
    • Journal of applied mathematics & informatics
    • /
    • v.13 no.1_2
    • /
    • pp.183-194
    • /
    • 2003
  • We will explain a new method for obtaining the nearly optimal domain for optimal shape design problems associated with the solution of a nonlinear wave equation. Taking into account the boundary and terminal conditions of the system, a new approach is applied to determine the optimal domain and its related optimal control function with respect to the integral performance criteria, by use of positive Radon measures. The approach, say shape-measure, consists of two steps; first for a fixed domain, the optimal control will be identified by the use of measures. This function and the optimal value of the objective function depend on the geometrical variables of the domain. In the second step, based on the results of the previous one and by applying some convenient optimization techniques, the optimal domain and its related optimal control function will be identified at the same time. The existence of the optimal solution is considered and a numerical example is also given.

CHARACTERIZATIONS OF GRADED PRÜFER ⋆-MULTIPLICATION DOMAINS

  • Sahandi, Parviz
    • Korean Journal of Mathematics
    • /
    • v.22 no.1
    • /
    • pp.181-206
    • /
    • 2014
  • Let $R={\bigoplus}_{\alpha{\in}\Gamma}R_{\alpha}$ be a graded integral domain graded by an arbitrary grading torsionless monoid ${\Gamma}$, and ⋆ be a semistar operation on R. In this paper we define and study the graded integral domain analogue of ⋆-Nagata and Kronecker function rings of R with respect to ⋆. We say that R is a graded Pr$\ddot{u}$fer ⋆-multiplication domain if each nonzero finitely generated homogeneous ideal of R is ⋆$_f$-invertible. Using ⋆-Nagata and Kronecker function rings, we give several different equivalent conditions for R to be a graded Pr$\ddot{u}$fer ⋆-multiplication domain. In particular we give new characterizations for a graded integral domain, to be a $P{\upsilon}MD$.

An Application of k-domain Discrete Wavelet Transform for the Efficient Representation of Green Function (파수영역 이산 웨이블릿 변환을 이용한 효율적인 그린함수 표현에 관한 연구)

  • 주세훈;김형동
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
    • /
    • v.12 no.7
    • /
    • pp.1110-1114
    • /
    • 2001
  • The discrete wavelet concept in the k-domain is applied to efficiently represent Green function of integral equations. Application of discrete wavelet concept to Green function in the k-domain can be implemented equivalently by using spatial domain variable-sized windows. The proposed method consists of constant Q-filtering, changing the center of coordinates, and transforming spatially filtered Green functions into those in the k-domain. A mathematical expression of Green function based on the discrete wavelet concept is derived and its characteristics are discussed.

  • PDF

S-Domain Equivalent System for Electromagnetic Transient Studies PART I : Frequency Dependent Network Equivalent (전자기 과도현상 해석을 위한 S 영역 등가시스템 PART I : 주파수 의존 시스템 등가)

  • 왕용필
    • The Transactions of the Korean Institute of Electrical Engineers A
    • /
    • v.52 no.11
    • /
    • pp.632-638
    • /
    • 2003
  • Modern power systems are very complex and to model them completely is impractical for electromagnetic transient studies. Therefore areas outside the immediate area of interest must be represented by some form of frequency dependent equivalent. The s-domain rational function form of frequency dependent equivalent does not need refitting if the simulation time-step is changed in the electromagnetic transient program. This is because the s-domain rational function coefficients are independent of the simulation time-step, unlike the z-domain rational function coefficients. S-domain rational function fitting techniques for representing frequency dependent equivalents have been developed using Least Squares Fitting(LSF). However it does not suffer the implementation error that exited in this work as it ignored the instantaneous term. This paper Presents the formulation for developing 1 Port Frequency Dependent Network Equivalent(FDNE) with the instantaneous term in S-domain and illustrates its use. This 1 port FDNE have been applied to the CIGRE Benchmark Rectifier test AC system. The electromagnetic transient package PSCAD/EMTDC is used to assess the transient response of the 1 port (FDNE) developed with Thevenin and Norton Equivalent network. The study results have indicated the robustness and accuracy of 1 port FDNE for electromagnetic transient studies.

DOMAIN BLOCK ESTIMATING FUNCTION FOR FRACTAL IMAGE CODING

  • Kousuke-Imamura;Yuuji-Tanaka;Hideo-Kuroda
    • Proceedings of the Korean Society of Broadcast Engineers Conference
    • /
    • 1999.06a
    • /
    • pp.57.2-62
    • /
    • 1999
  • Fractal coding is image compression techniques using one of image characteristics self-transformability. In fractal image coding, the encoding process is to select the domain block similar to a range block. The reconstructed image quality of fractal image coding depends on similitude between a range block and the selected domain block. Domain block similar to a range blocks. In fact, the error of the reconstructed image adds up the generated error in encoding process and the generated error in decoding process. But current domain block estimating function considered only the encoding error. We propose a domain block estimating function to consider not only the encoding error but also the decoding error. By computer simulation, it was verified to obtain the high quality reconstructed image.