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Dosimetric Comparison of Noncoplanar and Coplanar Volumetric Modulated Arc Therapy Plans for Esophageal Cancer

  • Park, So-Yeon
    • 한국의학물리학회지:의학물리
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    • 제31권4호
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    • pp.179-188
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    • 2020
  • Purpose: We compared noncoplanar volumetric modulated arc therapy (ncVMAT) plans to coplanar VMAT (cVMAT) plans by evaluating the dosimetric quality of each for esophageal cancer. Methods: Twenty patients treated for esophageal cancer with the cVMAT technique were retrospectively selected. The cVMAT plans consisted of three coplanar full arc beams. The ncVMAT plans consisted of two coplanar full arc beams and one noncoplanar partial arc beam ranging from 45° to 315° with a couch rotation angle of 315°±5°. For dosimetric evaluation, the dose-volumetric (DV) parameters of the planning target volume (PTV) and organs at risk (OARs) were calculated for all VMAT plans. Results: No clinically noticeable differences between the cVMAT and ncVMAT plans were observed in the DV parameters of the PTV. For the lungs, the V13 Gy and mean dose for ncVMAT plans were smaller than those for cVMAT plans, showing statistically significant differences. For the heart, the values of the maximum dose for cVMAT and ncVMAT plans were 53.8±2.9 and 50.9±3.3 Gy, respectively (P=0.004). For the spinal cord, the values of the maximum dose for cVMAT and ncVMAT plans were 37.1±5.1 and 34.7±5.7 Gy, respectively (P<0.001). Conclusions: The use of ncVMAT plans provides better PTV coverage and sparing of OARs compared to that of cVMAT plans for long, tube-like esophageal cancer. For esophageal cancer, the ncVMAT plans showed a more favorable plan quality than the cVMAT plans.

New Obligations of Health Insurance Review and Assessment Service: Taking Full-fledged Action Against the COVID-19 Pandemic

  • Yoo, Seung Mi;Chung, Seol Hee;Jang, Won Mo;Kim, Kyoung Chang;Lee, Jin Yong;Kim, Sun Min
    • Journal of Preventive Medicine and Public Health
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    • 제54권1호
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    • pp.17-21
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    • 2021
  • In 2020, the coronavirus disease 2019 (COVID-19) pandemic has caused unprecedented disruptions to global health systems. The Korea has taken full-fledged actions against this novel infectious disease, swiftly implementing a testing-tracing-treatment strategy. New obligations have therefore been given to the Health Insurance Review and Assessment Service (HIRA) to devote the utmost effort towards tackling this global health crisis. Thanks to the universal national health insurance and state-of-the-art information communications technology (ICT) of the Korea, HIRA has conducted far-reaching countermeasures to detect and treat cases early, prevent the spread of COVID-19, respond quickly to surging demand for the healthcare services, and translate evidence into policy. Three main factors have enabled HIRA to undertake pandemic control preemptively and systematically: nationwide data aggregated from all healthcare providers and patients, pre-existing ICT network systems, and real-time data exchanges. HIRA has maximized the use of data and pre-existing network systems to conduct rapid and responsive measures in a centralized way, both of which have been the most critical tactics and strategies used by the Korean healthcare system. In the face of new obligations, our promise is to strive for a more responsive and resilient health system during this prolonged crisis.

단일치 상실을 레진 접착 고정성 보철물로 수복한 증례 (Resin bonded fixed prosthesis for single tooth restoration: A case report)

  • 김은경;이종혁
    • 대한치과보철학회지
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    • 제55권3호
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    • pp.325-330
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    • 2017
  • 단일 치아 상실 시 전부피개관을 유지장치로 사용하는 고정성 보철이나 임플란트를 이용한 치료가 우선적으로 선택되어 사용되고 있다. 하지만 전부 피개관 지대치 형성을 위해서는 건전한 치질을 많이 삭제해야 한다는 단점이 있다. 임플란트의 경우 인접 치아의 손상을 피할 수 있으나 환자의 구강 상태와 전신 상태에 따라 불가능하거나 일정기간 연기해야 하는 경우도 있다. 본 증례에서는 최소한의 치질 삭제로 젊은 환자와 치은 퇴축이 있는 환자의 단일 치아 상실을 수복하기 위해 레진 접착 고정성 보철물을 선택하였다. 모든 환자들이 심미적, 기능적으로 만족하였기에 이를 보고하는 바이다.

근관 치료 후 수복 방법이 파절 강도와 파절 양상에 미치는 영향 (The Effect of Restorative Method on Fracture Strength and Fracture Pattern in Endodontically Treated Teeth)

  • 안동국;조인호;신수연
    • 구강회복응용과학지
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    • 제21권2호
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    • pp.133-142
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    • 2005
  • The purpose of this study was to evaluate interaction of restorative method according to amount of remaining clinical crown length. For the study, sixty healthy mandibular premolars with no dental caries were chosen. Specimens with clinical crown length of 1 mm, 2 mm, 3 mm above the cemento-enamel junction(CEJ) were prepared and root canal treatment was conducted using Ni-Ti rotaty files. Thirty specimens were restored with $LuxaCore^{(R)}$ and thirty were restored with casting posts. All specimens were restored with full coverage crowns and the fracture strength was teseted with the MTS universal testing marchine. The fracture pattern was observed by measuring the distance between CEJ and fracture line. From the results above, the fracture strength seems to be influenced more by amount of remaining clinical crown length than restorative method. Good prognosis could be expected, when more than 2mm of clinical crown length is retained. In the future, the further studies on restorative method, to increase fracture strength of teeth will be necessary.

동종사체진피와 배양한 자가상피세포를 이용한 선천성 피부 형성 부전증 환자의 치험례 (Treatment of Aplasia Cuti Congenita Using Allogenic Dermal matrix and Cultured Epithelial Autograft: A Case Report)

  • 이진화;김용규;이상준
    • Archives of Plastic Surgery
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    • 제33권5호
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    • pp.672-675
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    • 2006
  • Purpose: The purpose of this study is to document the surgical methods used in infants with aplasia cutis congenita treated with allogenic dermal matrix and cultured epithelial autografts. Methods: The large defects in both lower legs were replaced with allogenic dermal matrix to avoid the postoperative hypertrophic scar contracture and a full-thickness skin biopsy was taken from right groin area simultaneously. We sent the specimen to a commercial laboratory for culture and obtained cultured epithelial autografts($Holoderm^{(R)}$) after 2 weeks, placed it over the allogenic dermal matrix. Results: The skin-defected area were nearly epithelialized after 2 weeks and there were no significant problem on during 6 months follow-up. Conclusion: The surgical method using allogenic dermal matrix and cultured epithelial autograft provided an excellent coverage of large skin defects of infant with aplasia cutis congenita.

Development of Distributed Generic Simulator (GenSim) through Invention of Simulated Network (simNetwork)

  • Koo, Cheol-Hea;Lee, Hoon-Hee;Cheon, Yee-Jin
    • Journal of Astronomy and Space Sciences
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    • 제28권3호
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    • pp.241-252
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    • 2011
  • A simulated network protocol provides the capability of distributed simulation to a generic simulator. Through this, full coverage of management of data and service handling among separated simulators is achieved. The distributed simulation environment is much more conducive to handling simulation load balancing and hazard treatment than a standalone computer. According to the simulated network protocol, one simulator takes on the role of server and the other simulators take on the role of client, and client is controlled by server. The purpose of the simulated network protocol is to seamlessly connect multiple simulator instances into a single simulation environment. This paper presents the development of a simulated network (simNetwork) that provides the capability of distributed simulation to a generic simulator (GenSim), which is a software simulator of satellites that has been developed by the Korea Aerospace Research Institute since 2010, to use as a flight software validation bench for future satellite development.

선천성 피부결손증의 치험 1례 (The Treatment of Congenital Cutis Aplasia)

  • 김용하;차규호;정재호;이경호;설정현
    • Journal of Yeungnam Medical Science
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    • 제9권2호
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    • pp.422-426
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    • 1992
  • 저자들은 회귀하고도 사망율이 높은 선천성 피부결손증 1례를 경험하고 국소피판과 피부이식으로써 치료하고 비교적 만족한 결과를 얻었기에 문헌고찰과 함께 보고하는 바이다.

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Effects of localised liquid fertilization of N, P, K and Ca on root development in Zoysia matrella, Cynodon dactylon and Stenotaphrum secundatum

  • Ow, Lai Fern;Yusof, Mohamed Lokman Mohd
    • Weed & Turfgrass Science
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    • 제7권1호
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    • pp.76-86
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    • 2018
  • Turfgrass species were evaluated for their rooting and foliar characteristics, and their interaction with the soil. The rooting system was divided into three compartments, one above another, such that the top and bottom compartments of the root system could be supplied with a nutrient deprived solution. Exposure of parts of the roots to nitrate deprivation caused a localised retardation of root initiation and extension, compared with zones receiving the full supply of nutrients. This resulted in considerable modification to root form, coupled with a significant depression in foliar growth. The extension of roots was the least affected by the deprivation of potassium. Phosphate and calcium deprivations gave rise to similar responses in root and foliar formation. Results from this study showed that external concentrations of nitrogen, phosphorus, potassium and calcium are required by the root system in varying amounts for optimal growth of roots. Turfgrass coverage and turf quality ratings further reinforced these findings. No significant difference was observed between the different grasses examined here. All three species responded similarly to the deprivation of the various nutrients. Results from this study confirmed that targeted fertilization programs are beneficial and can help reduce cost, chemical usage and prevent leachate and contamination.

넓은 유리 광 배 근피부 판을 이용한 하지 재건술 (Reconstruction of the Lower Extremities with the Large Latissimus Dorsi Myocutaneous Free Flap)

  • 이준모;허달영
    • Archives of Reconstructive Microsurgery
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    • 제9권1호
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    • pp.80-87
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    • 2000
  • Acute high speed accidents that results in full thickness skin defect and exposure of tendon, nerve, vessel and periosteum over denuded bone demands soft tissue coverage. Exposed bone often ensues chronic infection and requires free flap transplantation which surely covers defects in one stage operation and enhances transport of oxygen-rich blood and converts a non-osteogenic or partially osteogenic site into a highly osteogenic site, but exposed bone which had performed free flap transplantation sometimes necroses and needs secondary bone procedure. Scar contracture limits joint motion should be excised and covered with normal soft tissue to restore normal range of motion. Authors have performed the large latissimus dorsi myocutaneous free flap in 8 cases of extensive soft tissue defect and exposed bone lesion in the leg and 1 case of the flap was failed. The secondary ilizarov bone procedure was performed in 3 of 8 cases. 2 cases of large burn scar contracture and 1 case of posttraumatic scar contracture in lower extremity were restored with the large latissimus dorsi myocutaneous free flap. Authors concluded that large latissimus dorsi myocutaneous free flap is the most acceptable microvascular procedure in large soft tissue defect combined with exposed periosteum and bone requiring secondary bone procedure and in large burn scar contracture limiting knee joint motion.

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L1014 분자운 핵에 대한 SRAO 6m 망원경을 이용한 분자선 관측연구 (MOLECULAR LINE STUDY OF L1014 WITH SRAO 6M TELESCOPE)

  • 이창원
    • 천문학논총
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    • 제20권1호
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    • pp.1-5
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    • 2005
  • We report molecular line observations of CO(1-0), $^{13}CO(1-0)$, CS(2-1), and HCN(1-0) with SRAO 6m telescope toward L1014-IRS which is thought to be a very faint infrared source embedded in previously known 'starless' core L1014. The CO(1-0) observations find several components with different velocities along the line of sight of L1014, $4km\;s^{-1}$ and between $40{\sim}50km\;s^{-1}$. We find a parsec scale CO molecular outflow at the $4km\;s^{-1}$ component for the first time the direction of which is coincident with that of the small scale (${\sim}500pc$) outflow previously found. Although the observation is not covered for whole area of the outflow, the size of the molecular outflow seems not very inconsistent with the expected age of L1014-IRS. More accurate size and shape of the molecular outflow from L1014-IRS will be determined from the full coverage mapping in CO over the outflow region in very near future.