Archives of Plastic Surgery

Korean Society of Plastic and Reconstructive Surgeons (대한성형외과학회)
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Treatment of Aplasia Cuti Congenita Using Allogenic Dermal matrix and Cultured Epithelial Autograft: A Case Report

동종사체진피와 배양한 자가상피세포를 이용한 선천성 피부 형성 부전증 환자의 치험례

  • Lee, Jin Hwa (Department of plastic and Reconstructive Surgery, College of Medicine, Inje University) ;
  • Kim, Yong Kyu (Department of plastic and Reconstructive Surgery, College of Medicine, Inje University) ;
  • Lee, Sang Joon (Department of plastic and Reconstructive Surgery, College of Medicine, Inje University)
  • 이진화 (인제대학교 의과대학 일산백병원 성형외과학교실) ;
  • 김용규 (인제대학교 의과대학 일산백병원 성형외과학교실) ;
  • 이상준 (인제대학교 의과대학 일산백병원 성형외과학교실)
  • Received : 2006.02.24
  • Published : 2006.09.10
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Abstract

Purpose: The purpose of this study is to document the surgical methods used in infants with aplasia cutis congenita treated with allogenic dermal matrix and cultured epithelial autografts. Methods: The large defects in both lower legs were replaced with allogenic dermal matrix to avoid the postoperative hypertrophic scar contracture and a full-thickness skin biopsy was taken from right groin area simultaneously. We sent the specimen to a commercial laboratory for culture and obtained cultured epithelial autografts($Holoderm^{(R)}$) after 2 weeks, placed it over the allogenic dermal matrix. Results: The skin-defected area were nearly epithelialized after 2 weeks and there were no significant problem on during 6 months follow-up. Conclusion: The surgical method using allogenic dermal matrix and cultured epithelial autograft provided an excellent coverage of large skin defects of infant with aplasia cutis congenita.

Keywords

References

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