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Treatment of Aplasia Cuti Congenita Using Allogenic Dermal matrix and Cultured Epithelial Autograft: A Case Report  

Lee, Jin Hwa (Department of plastic and Reconstructive Surgery, College of Medicine, Inje University)
Kim, Yong Kyu (Department of plastic and Reconstructive Surgery, College of Medicine, Inje University)
Lee, Sang Joon (Department of plastic and Reconstructive Surgery, College of Medicine, Inje University)
Publication Information
Archives of Plastic Surgery / v.33, no.5, 2006 , pp. 672-675 More about this Journal
Abstract
Purpose: The purpose of this study is to document the surgical methods used in infants with aplasia cutis congenita treated with allogenic dermal matrix and cultured epithelial autografts. Methods: The large defects in both lower legs were replaced with allogenic dermal matrix to avoid the postoperative hypertrophic scar contracture and a full-thickness skin biopsy was taken from right groin area simultaneously. We sent the specimen to a commercial laboratory for culture and obtained cultured epithelial autografts($Holoderm^{(R)}$) after 2 weeks, placed it over the allogenic dermal matrix. Results: The skin-defected area were nearly epithelialized after 2 weeks and there were no significant problem on during 6 months follow-up. Conclusion: The surgical method using allogenic dermal matrix and cultured epithelial autograft provided an excellent coverage of large skin defects of infant with aplasia cutis congenita.
Keywords
Aplasia cutis congenita; Cultured epithelial autograft;
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  • Reference
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