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Evidence-Based Clinical Practice Guideline for Fluid Therapy to Prevent Contrast-induced Nephropathy (조영제 유발 신장병증 예방을 위한 수액요법에 관한 근거기반 임상실무지침 개발)

  • Lee, Kyung Hae;Shin, Kyung Min;Lee, Hyeon Jeong;Kim, So Young;Chae, Jung Won;Kim, Mi Ra;Han, Min Young;Ahn, Mi Sook;Park, Jin Kyung;Chung, Mi Ae;Chu, Sang Hui;Hwang, Jung Hwa
    • Journal of Korean Clinical Nursing Research
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    • v.23 no.1
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    • pp.83-90
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    • 2017
  • Purpose: This study was to develop evidence-based clinical practice guideline in order to prevent contrastinduced nephropathy (CIN) for patients undergoing percutaneous coronary intervention (PCI). Methods: The guideline was developed based on the "Scottish Intercollegiate Guidelines Network (SIGN)". The first draft of guideline was developed through 5 stages and evaluated by 10 experts.(1) Clinical questions were ensured in PICO format.(2) Two researchers conducted a systematic search through electronic database, identifying 170 studies. We selected 27 full text articles including 16 randomized clinical trials, 7 systematic reviews, and 4 guidelines. Quality of each studies were evaluated by the Cochran's Risk of Bias, AMSTAR, K-AGREEII. Among the studies, 11 studies were excluded.(3) The strength of recommendations were classified and quality of recommendations were ranked.(4) Guideline draft was finalized.(5) Content-validation was conducted by an expert group. All contents were ranked above 0.8 in CVI. Results: Evidence-based clinical practice guideline to prevent CIN was dveloped.(1) The guideline for preventing CIN recommends using 0.9% saline.(2) Standardized rate of fluid therapy is 1 to 1.5ml/kg/hr.(3) Execute hydration for 6~12hrs before PCI and after PCI. Conclusion: This study suggests evidence-based clinical practice guideline for preventing CIN which can be more efficiently used in clinical practice.

High Bit-Rates Quantization of the First-Order Markov Process Based on a Codebook-Constrained Sample-Adaptive Product Quantizers (부호책 제한을 가지는 표본 적응 프로덕트 양자기를 이용한 1차 마르코프 과정의 고 전송률 양자화)

  • Kim, Dong-Sik
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.49 no.1
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    • pp.19-30
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    • 2012
  • For digital data compression, the quantization is the main part of the lossy source coding. In order to improve the performance of quantization, the vector quantizer(VQ) can be employed. The encoding complexity, however, exponentially increases as the vector dimension or bit rate gets large. Much research has been conducted to alleviate such problems of VQ. Especially for high bit rates, a constrained VQ, which is called the sample-adaptive product quantizer(SAPQ), has been proposed for reducing the hugh encoding complexity of regular VQs. SAPQ has very similar structure as to the product VQ(PQ). However, the quantizer performance can be better than the PQ case. Further, the encoding complexity and the memory requirement for the codebooks are lower than the regular full-search VQ case. Among SAPQs, 1-SAPQ has a simple quantizer structure, where each product codebook is symmetric with respect to the diagonal line in the underlying vector space. It is known that 1-SAPQ shows a good performance for i.i.d. sources. In this paper, a study on designing 1-SAPQ for the first-order Markov process. For an efficient design of 1-SAPQ, an algorithm for the initial codebook is proposed, and through the numerical analysis it is shown that 1-SAPQ shows better quantizer distortion than the VQ case, of which encoding complexity is similar to that of 1-SAPQ, and shows distortions, which are close to that of the DPCM(differential pulse coded modulation) scheme with the Lloyd-Max quantizer.

A study on the relationship between the onshore and offshore Chinese Yuan markets (중국 역내·외 위안화 현물시장간의 상호 연계성 연구)

  • Lee, Woosik;Chun, Heuiju
    • Journal of the Korean Data and Information Science Society
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    • v.26 no.6
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    • pp.1387-1395
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    • 2015
  • Since the financial crisis of 2008, the People's Republic of China has aggressively been pursuing the internationalization of the Chinese Yuan or Renminbi. In this regard, rapidly increasing use of the Chinese Yuan in the onshore and offshore markets are important milestones. This paper analyzes relationship between the onshore and offshore Chinese Yuan spot markets. Major findings of this paper are as follows : First, there is full feedback relationship between the Onshore and Offshore Chinese Yuan Markets. Second, the difference between the yuan's offshore exchange rate and the onshore was getting tight. Third, the offshore Yuan market affects on the onshore market based on the empirical tests.

Gamma-ray-induced skin injury in the mini-pig: Effects of irradiation exposure on cyclooxygenase-2 expression in the skin (감마선조사에 의한 돼지 피부장애에 cyclooxygenase-2의 발현변화)

  • Kim, Joong Sun;Park, Sunhoo;Jang, Won Seok;Lee, Sun Joo;Lee, Seung Sook
    • Journal of Radiation Protection and Research
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    • v.40 no.1
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    • pp.65-72
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    • 2015
  • The basic concepts of radiation-induced skin damage have been established, the biological mechanism has not been studied. In this study, we have examined the effects of gamma rays on skin injury and cyclooxygenase(COX)-2 expression. Gamma irradiation induced clinicopathological changes in a dose- and time-dependent manner in mini-pig skin. The histological changes were consistent with the changes in gross appearance at 12 weeks after irradiation. After three days' irradiation, apoptotic cells in the basal layer were found more frequently in irradiated skin than in normal skin, with the magnitude of the effect being dose-dependent. The thickness of the epidermis transiently increased 3 days after irradiation, and then gradually decreased, although changes in the epithelial thickness of the irradiated field were not observed with irradiation doses over 50 Gy. In the epithelium, there was an initial degenerative phase, during which the rate of basal cell depletion was dependent on the radiation dose (20-70 Gy). One week after irradiation, COX-2 expression was mostly limited to the basal cell layer and was scattered across these cells. High COX-2 expression was detected throughout the full depth of the skin after irradiation. The COX-2 protein is upregulated after irradiation in mini-pig skin. These histological changes associated with radiation exposure dose cause the increased COX-2 expression in a dose-dependent fashion.

Fermentation of Cucurbita maxima Extracts with Microganisms from Kimchi (김치 유래 유산균을 이용한 단호박 발효음료 제조 기술 개발)

  • Roh, Hyun-Ji;Kim, Gi-Eun
    • KSBB Journal
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    • v.24 no.2
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    • pp.149-155
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    • 2009
  • 19 strains, which could be identified as Lactobacillus sp. were isolated. The Cucurbita maxima has been known as a traditional healthy food and variable positive effects on the human body were already reported. In this study we tried to develop a production process for a healthy fermented drink with Cucurbita maxima and strains originated from Kimchi. Many kinds of lacctobacci species existed in the fermented food cannot survive in the acidic conditions in the stomach. So we tried to search and select a strain, which can arrive to the small intestine. A species of a Lactobacillus named as C332 was identifed as Lactobacillus plantarum and selected for the fermentation process. With the treatment with artificial gastric juice and artificial bile the survival rate of the cells could be calculated. The physiological characteristics at the variable conditions have been tested. After fermentation process the sensoric tests on the product with panels were tried. The most of the cells could survive in the acidic conditions and falcultive anaerobe. Especially some antibacterial effects aganinst E.coli were also found. With all kinds of the results from our research the fermented Cucurbita maxima drink can be a successful item in the market.

Economic Analysis of Geothermal Energy and VMD Desalination Hybrid Process (지열에너지와 진공 막 증류법을 활용한 해수담수화 연계형 공정의 경제성 분석)

  • Park, Kiho;Kim, Jin Hyun;Kim, Hyuk Soo;Lee, Kwan-Young;Yang, Dae Ryook;Kim, Kyung Nam
    • Clean Technology
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    • v.20 no.1
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    • pp.13-21
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    • 2014
  • Because of the water scarcity caused by the increase of salinity in the underground water, seawater desalination stands out as one of the most promising solution. As there are so much energy costs in operating desalination plants, new hybrid process which is more effective should be researched. A geothermal VMD (vacuum membrane distillation) hybrid process is a competitive alternative for seawater desalination. Because geothermal energy has significant characteristics of high capacity factor to operate the power plant at full capacity for 24 hour per day, it can be a priority heat source of VMD superior to any other renewable energies such as solar and wind power. In this study, we design a geothermal VMD hybrid process, analyze it economically and finally compare the result with a case of conventional VMD process. Geothermal VMD hybrid process generates $23,822,409 of NPV (net present value) more than the conventional VMD process in case of 5% discount rate. The break-even point between these processes is 5.36 year. Sensitivity analysis indicates that steam cost is the most decisive influence variable to the economic outcome.

New Columnar Apple Variety 'Tinkerbell' for Pollenizer (사과 무측지성 수분수용 신품종 '팅커벨')

  • Kwon, Soon-Il;Kwon, Young Soon;Park, Jong-Taek;Kim, Mok-Jong;Kim, Jeong-Hee
    • Journal of Bio-Environment Control
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    • v.25 no.3
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    • pp.173-176
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    • 2016
  • This research was performed to breed new columnar-typed apple variety for pollinator in apple orchard. We cross-fertilized 'Hongro' that was an ovary parent and 'Maypole' a pollen parent in 2003. We gathered seeds in 2003 and sowed after breaking of dormancy in 2004. Seedlings was been growth and development till flowering. After fruit setting, We investigated characteristics of growth and fruit including mating compatibility from 2010 to 2012, then finally selected '03-2-95' named 'Tinkerbell' in 2012, registered as new variety on Korea Seed & Variety Service in 2015. The full bloom stage of 'Tinkerbell' was later 2 days then of 'Maypole'. Tree habit of 'Tinkerbell' was alike to of 'Maypole', for example weak tree vigor, columnar type. But there were many different characteristics between 'Tinkerbell' and 'Maypole'. Fruit shape of 'Tinkerbell' was ovoid whereas of 'Maypole' was ellipsoid. Fruit of 'Tinkerbell' was bigger, smoother skin, no waxy bloom than of 'Maypole'. Fruit of 'Tinkerbell' was more delicious than of 'Maypole' because of having higher soluble sugar content and lower titratable acidity. 'Tinkerbell' was excellent pollinator in apple orchard. Because of having high fruit setting rate with major apple varieties and a narrow tree width that was advantageous as pollinator in apple high density system.

Real-Time DSP Implementation of IMT-2000 Speech Coding Algorithm (IMT-2000 음성부호화 알고리즘의 실시간 DSP 구현)

  • Seo, Jeong-Uk;Gwon, Hong-Seok;Park, Man-Ho;Bae, Geon-Seong
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.38 no.3
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    • pp.304-315
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    • 2001
  • In this paper, we peformed the real-time implementation of AMR(Adaptive Multi-Rate) speech coding algorithm which is adopted for IMT-2000 service using TMS320C6201, i.e., a Texas Instrument´s fixed-point DSP. With the ANSI C source code released from ETSI, optimization is performed to make it run in real-time with memory as small as possible using the C compiler and assembly language. Implemented AMR speech codec has the size of 32.06 kWords program memory, 9.75 kWords data RAM memory, and 19.89 kWords data ROM memory. And, The time required for processing one frame of 20 ms length speech data is about 4.38 ms, and it is short enough for real-time operation. It is verified that the decoded result of the implemented speech codec on the DSP is identical with the PC simulation result using ANSI C code for test sequences. Also, actual sound input/output test using microphone and speaker demonstrates its proper real-time operation without distortions or delays.

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A Critical Evaluation on the Pension Privatization Reform in Chile (칠레 연금민영화 개혁에 대한 평가)

  • Cho, Young-Hoon
    • Korean Journal of Social Welfare
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    • v.50
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    • pp.87-108
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    • 2002
  • According to Neo-liberalism, the privatization of social security systems is pivotal for a country's economic growth and the wellbeing of its people, because such systems hinder the full operation of the market, eventually leading the national economy to collapse. The Chilean case of pension privatization is often cited as a good evidence for the Neo-liberal argument. Neo-liberalists say that Chile has experienced a rapid economic growth and retirees have enjoyed a much more pension payment since the national pension system was successfully privatized in 1981. The primary purpose of this article is to provide a critical review on the results of the Chilean pension privatization reform implemented in 1981. This study is intended to give an objective understanding of the reform because the existing evaluations, particularly those from the neo-liberalism, over-emphasize the bright sides of the reform. for this purpose, this article will pay a particular attention to the change in the level of pension payment after the reform. The conclusion of this study is that, contrary to the argument of Neo-liberalism, the pension reform has lowered the level of pension payment and, compared to the old public pension, has made the lives of ordinary retirees less secure. Reorganization of the social security system is more desirable than privatization as a remedy for the current problems of the welfare state.

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Organizational Culture and Community-Centered Social Inclusion Orientation Among Social Service Organizations for People with Disabilities: Focused on Market Orientation As a Mediator (장애인복지기관의 조직문화유형과 지역사회중심사회통합지향성에 관한 연구 : 시장지향성의 매개효과를 중심으로)

  • Choi, Jae-Sung;Choi, Jung-Ah;Jung, So-Yon
    • Korean Journal of Social Welfare
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    • v.61 no.1
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    • pp.5-32
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    • 2009
  • The purpose of this study is to examine the effects of organizational culture types (rational culture, developmental culture, group culture, and hierarchical culture) on Community-Centered Social Inclusion Orientation(COSI) among social service organizations for people with disabilities. More specifically, this study developed and empirically tested two theoretical models where each of organizational culture types were hypothesized to affect COSI either directly or indirectly through market orientation. For data collection, self-administered type questionnaires were mailed to 416 social service organizations for people with disabilities across the nation and 293 responded (response rate: 70.4%) from June 1 to September 22, 2006. For analysis, however, only 263 respondents were used, excluding Independent living centers due to their small size and short history. Structural Equation Modeling was employed for analysis and Full Information Maximum Likelihood was used for estimation. Findings indicated that market orientation had a significant effect on COSI. In addition, developmental culture and hierarchical culture were found to affect COSI directly while rational culture and group culture were found to affect COSI indirectly through market orientation. These findings imply that market orientation needs to be emphasized as a strategy in order to enhance social inclusion orientation for those organizations. Given that all the four types of organizational culture have direct or indirect impacts on COSI, those organizations are also advised to develop the four types of organizational culture harmoniously rather than one single type of organizational culture.

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