• Journal of the Society of Cosmetic Scientists of Korea
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• v.45 no.2
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• pp.209-216
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• 2019

Ultraviolet rays (UV) cause photoaging by inducing skin photodamages such as erythema and sunburn. Silymarin is a mixture of antioxidant polyphenols extracted from Silybum marianum fruit (S. m), which is known as milk thistle. It is known to protect skin tissues from UV treatment and antioxidant effects. In this study, we aimed to identify the photoprotective effects of S. m extract, which has silymarin in the epidermis layer of the skin. We found that the extract can function as a UV filter, so it can reduce DNA damage by UV treatment. Especially, we found that, in the stratum corneum, the extract can suppress the protein carbonylarion and DNA damages caused by suberythemal dose of UV treatment which does not induce erythema in the skin. UV treatment also increased protein carbonylation levels in the stratum corneum by oxidation, but it was prevented by applying the extract. The extract can absorb UV with minimal phototoxicity. Together, our study suggests that S. m extract can be used as a photo-protective ingredient to avoid photoaging of the skin.

• Korean Journal of Agricultural Science
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• v.45 no.3
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• pp.325-353
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• 2018

Agricultural systems in South Asian countries are dominated by smallholder farmers. Additionally, these farmers have limited access to pre- and post-harvest technologies due to their high initial cost. The lack of these technologies in postharvest handling is responsible for 20% to 44% of fruit and vegetable losses. These high losses are largely the result of a generally weak basic postharvest infrastructure for the preservation of products, which avoids damage from improper handling, transportation, packaging, and storage. High postharvest losses of products negatively affect food availability, food security, and nutrition, as the producer is able to sell less of the farm yield and the net availability of these food commodities for consumption is reduced. An underlying cause of these postharvest losses is the limited awareness and knowledge bases of stakeholders (researchers, farmers, governments, non-governmental organizations, and merchants) in the traditional supply chains in which these losses occur. The analysis presented in this paper explores the state of postharvest practice in South Asian countries and discusses options for low-cost postharvest technologies in the region that can support small-scale farmers and provide a viable pathway for supply to the market, joining with modern value chains and bringing about individual and regional reduction in postharvest losses of fruits and vegetables. The improvement of basic and simple low-cost technologies through precise research efforts has the potential to prevent such huge losses of products, and help meet the ever-increasing demand for food in South Asian countries.

• Proceedings of the Korea Society of Poultry Science Conference
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• 2006.11a
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• pp.28-42
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• 2006

Tannins are phenolic compounds that precipitate proteins and composed of a very diverse group of oligomers and polymers. Tannins are potential biological antioxidants, which are widely believed to be an important line of defense against oxidative damage and may participate in the prevention of cancer and cardiovascular disease. Persimmon(Diospyros kaki L.) has been cultivated in East Asia and is a good source of nutritional antioxidant vitamins, carotenoids and tannins. In general persimmon peel was regarded as a waste matter, although based on recent studies, the peel contains more carotenoids and polyphenols than pulp. Several investigation conducted in experimental animals have reported that dietary persimmon fruit and peel effectively lowered the levels of plasma total cholesterol and LDL-cholesterol. We conducted experiments to investigate in vitro antioxidative activities of persimmon peel powder (PP) and its soluble tannin extract (ST) and their dietary effects on productive performances and physiological responses in poultry. The PP and ST exhibited in vitro antioxidative activity in SOD - like activity model. The yolk color and eggshell color were significantly improved by the addition of PP and ST into layer diets. The contents of total cholesterol, triacylglycerol and phospholipid of liver in the groups fed diets containing PP and ST tended to be reduce as compared with those of control. With adding of PP and ST, Haugh unit was increased after 7 and 14 days of storage. In conclusion, PP and ST can be used as valuable feed additives for reducing hepatic lipid contents without harmful effects on overall productive performances and physiological responses in laying hens.

• Herbal Formula Science
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• v.28 no.4
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• pp.327-337
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• 2020

Objective : Citri Unshius Pericarpium is the dried peel of mature fruit of Citrus unshiu Markovich and has been used to treat indigestion, vomiting, and removal of phlegm. This study investigated the hepatoprotective and antioxidant effect of CEE (Ethanol extract of Citri Unshius Pericarpium) in cadmium (CdCl₂)-treated HepG2 cells. Methods : Component analysis of Citri Unshius Pericarpium was analyzed by UPLC with C₁₈ column. Cell viability was determined by MTT assay. The enzyme activity of superoxide dismutase (SOD) and the level of reactive oxygen species (ROS) and reduced glutathione (GSH) were analyzed using commercially available kits. Results : Cadmium caused severe HepG2 cell death. Cadmium also increased ROS production, consistent with depletion of GSH and inhibition of the SOD enzyme. However, CEE treatment reduced cell death and relieved oxidative stress caused by cadmium toxicity. CEE lowered ROS levels and improved depletion of GSH levels. CEE also enhanced the enzymatic activity of SOD. In component analysis, hesperidin was the most abundant of the five marker compounds (Narigenin, Narigin, Narirutin, Hesperidin and Hesperidin), which assumes that hesperidin partially contributed to the antioxidant activity of CEE. Conclusion : These results suggested that CEE could be a potential substance to solve heavy metal-related health problems. In particular, inhibition of oxidative stress by CEE can be a way to treat liver damage caused by cadmium.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.7
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• pp.415-422
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• 2018

Lycorma delicatula, known as spotted lanternfly, is a planthopper native to Southeast Asia, including Vietnam, India and South China. This species damages local fruit trees and has spread rapidly in South Korea in recent years. The purpose of this study is to present the methods and estimation results pertaining to the risk of invasive species like Lycorma delicatula. We used a partial budget (PB) method to assess direct income reduction of farm households and a partial equilibrium (PE) model to examine social welfare change from the outbreak of Lycorma delicatula. We also estimated the future economic impacts of Lycorma delicatula under various climate scenarios considering habitat suitability. As climate change progresses, domestic ecosystems are expected to become increasingly vulnerable to pest outbreaks leading to further economic damage. We believe that this study can be a base to evaluate efficiency of the national pest control and quarantine system.

• Proceedings of the Korea Society of Poultry Science Conference
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• 2005.11a
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• pp.17-30
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• 2005

Lycopene is the red-coloured carotenoid predominantly found in tomato fruit and one of the major carotenoids in the diets of North American and Europeans. Interest in lycopene is growing rapidly following the recent publication of its effects as a natural antioxidant and prevention of cardiovascular disease and cancers. Lycopene, a polyene hydrocarbon carotenoid haying 13 double bond, of which 11 are conjugated double bonds in a linear array exhibits a strong antioxidant property almost twice as strong as that of ${\beta}$-carotene. Lycopene has been shown in recent epidemiological and experimental studies to protect against oxidative damage of DNA which plays an important part in development of various cancer. Lycopene also contribute towards reducing the risk of cardiovascular diseases by preventing oxidation of low-density lipoprotein(LDL) cholesterol. This review summarize our knowledge and the current understanding of lycopene in human health as well as the results of experiments we conducted. We conducted experiments for investigating the effects of antioxidant in broiler and the possibilities of production of high quality eggs containing lycopene by the dietary lycopene supplementation with synthetic lycopene or tomato paste. The results shows that thiobarbituric acid reaction substances(TBARS) values in process of LDL oxidation in blood serum of broiler were significantly decreased by dietary lycopene and tomato paste. The dietary lycopene supplementation resulted in improved egg yolk color and in decreased the malondialdehyde (MDA) of egg yolk after 4 wk of storage at room temperature significantly(P<0.05). The dietary tomato paste was more effective in the MDA reduction compared to the lycopene(P<0.05). The contents of lycopene in egg yolk of the lycopene supplementation groups were significantly higher than those of the control group.

• Journal of Korean society of Dental Hygiene
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• v.9 no.4
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• pp.864-873
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• 2009

Objectives : This study was to collect data about oral health to develop preschool children' oral health program. Methods : This research was from July 20th to August 20th, 2008 with self-administrated questionnaires by post and e-mail. The response rate was 57.6%(144 of 250). Results : 1. Daycare center provided fruit(64.6%), bread(56.9%), milk(82.6%), yoghurt(47.9%). daycare center tend to provide cariogenic snacks and drinks such as bread, yoghurt. 2. 73.6% of teachers said they reward children with sweets for good behavior. 3. Activities related to oral health was done in daycare center were : children brush their teeth with fluoride toothpaste(79.9%), catering staff receive the education about nutrition(79.2%), children participate in the activities and training related to food(78.5%), using sugary food at a birthday party(77.3%), annual dental health check-up by a dentist(65.3%). 4. The percentages of guiding principles based on documentation in the topic of the oral health were : coping with a situation where a child injured his or her teeth(76.4%), annual dental health checkup by a dentist(72.2%), teachers supervise children's tooth brushing using a fluoride toothpaste(70.8%). 5. Documented guide or course for oral health includes the following; training for coping with tooth damage(76.4%), annual dental health check-up(72.2%), and coaching children to brush their teeth with toothpaste that contains fluoride(70.8%). Conclusions : It is believed that for better children's oral healthcare, childcare teacher should be given a range of in-depth oral health program. Furthermore, through detailed analysis on the documented guide of oral health, cooperation from the associated organization will be required to have the guide placed at the childcare center.

• Korean Journal of Environmental Agriculture
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• v.33 no.3
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• pp.184-188
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• 2014

BACKGROUND: White stain symptom caused by Acremonium acutatum and Trichothecium roseum, is one of the most important diseases on the grape. This disease occurs national-wide in Korea and causes irreversible damage on grape, at harvest season. This study was conducted to develop environment-friendly control method against white stain symptom. METHODS AND RESULTS: Environment-friendly materials were tested for control activity against A. acutatum and T. roseum in vitro and in vivo. The effect of environment-friendly materials against white stain symptom on grape in farmer's greenhouse was examined. The materials, NaDCC and sulphur, were sprayed three times on the leaves and fruit of grape at the two sites of farmer's field, Anseong and Hwaseong of Gyeounggi. To evaluate control effect of NaDCC and sulphur against white stain symptom, the disease severity was investigated after the two materials were sprayed from the disease onset three times at the 7-day intervals. NaDCC showed efficacy of 59.71% for Kyoho and 72.26% for Campbell-Early, and sulphur showed 78.31% for Koyho and 66.19% for Campbell-Early. CONCLUSION: We were selected sulphur and Sodium-Dichloroisocyannurate(NaDCC) based on the results of experiments in vitro. In field test, sulphur and NaDCC showed suppressive effect in the white stain symptom of grape. These results suggested that NaDCC and sulphur selected can be used as control agents for controlling white stain symptom on grape.

• Biomolecules & Therapeutics
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• v.14 no.1
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• pp.1-10
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• 2006

Drug dependence deals a heavy socioeconomic burden to the society. For adolescents, the damage from drug dependence is greater than adults considering their higher susceptibility to drug effect and increasing chance for violence leading to criminal punishment process. Habitual drug use depends on genetic and environmental factors and the complex interactions between the two. Mammalian model systems have been useful in understanding the neurochemical and cellular impacts of abused drugs on specific regions of the brain, and in identifying the molecular targets of drugs. More elucidation is required whether biological effects of drugs actually cause the habitual dependence at the cellular level. Although there is much insight available on the nature of drug abuse problems, none of the systems designed to help drug dependent individuals is efficient in screening functional ingredients of the drug, and thus resulting in the failure of helping drug dependent individuals recover from drug dependence. Alternative model systems draw the attention of researchers, such as the invertebrate model systems of nematodes (Caenorhabditis elegans) and fruit flies (Drosophila melanogaster). These models should provide new insight into the mechanisms leading to the behavior of drug users (even functional studies analyzing molecular mechanism), and screening useful components to help remove drug dependence among drug users. The relatively simple anatomy and gene expression of the invertebrate model systems should enable researchers to coordinate current knowledge on drug abuse. Furthermore, the invertebrate model systems should facilitate advance in experiments on the susceptibility of specific genetic backgrounds and the interaction between genetic factors to drug dependence.

• Korean Journal of Agricultural and Forest Meteorology
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• v.12 no.1
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• pp.63-73
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• 2010

A comprehensive mapping project for agroclimatic zoning in South Korea will end by April 2010, which has required 4 years, a billion won (ca. 0.9 million US dollars) and 22 experts from 7 institutions to complete it. The map database from this project may be categorized into primary, secondary and analytical products. The primary products are called "high definition" digital climate maps (HD-DCMs) and available through the state of the art techniques in geospatial climatology. For example, daily minimum temperature surfaces were prepared by combining the climatic normals (1971-2000 and 1981-2008) of synoptic observations with the simulated thermodynamic nature of cold air by using the raster GIS and microwave temperature profiling which can quantify effects of cold air drainage on local temperature. The spatial resolution of the gridded climate data is 30m for temperature and solar irradiance, and 270m for precipitation. The secondary products are climatic indices produced by statistical analysis of the primary products and includes extremes, sums, and probabilities of climatic events relevant to farming activities at a given grid cell. The analytical products were prepared by driving agronomic models with the HD-DCMs and dates of full bloom, the risk of freezing damage, and the fruit quality are among the examples. Because the spatial resolution of local climate information for agronomic practices exceeds the current weather service scale, HD-DCMs and the value-added products are expected to supplement the insufficient spatial resolution of official climatology. In this lecture, state of the art techniques embedded in the products, how to combine the techniques with the existing geospatial information, and agroclimatic zoning for major crops and fruits in South Korea will be provided.