• Clinical and Experimental Reproductive Medicine
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• 제48권2호
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• pp.111-123
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• 2021

Objective: Using domestic cats as a biomedical research model for fertility preservation, the present study aimed to characterize the influences of ovarian tissue encapsulation in biodegradable hydrogel matrix (fibrinogen/thrombin) on resilience to cryopreservation, and static versus non-static culture systems following ovarian tissue encapsulation and cryopreservation on follicle quality. Methods: In experiment I, ovarian tissues (n=21 animals; 567 ovarian fragments) were assigned to controls or hydrogel encapsulation with 5 or 10 mg/mL fibrinogen (5 or 10 FG). Following cryopreservation (slow freezing or vitrification), follicle viability, morphology, density, and key protein phosphorylation were assessed. In experiment II (based on the findings from experiment I), ovarian tissues (n=10 animals; 270 ovarian fragments) were encapsulated with 10 FG, cryopreserved, and in vitro cultured under static or non-static systems for 7 days followed by similar follicle quality assessments. Results: In experiment I, the combination of 10 FG encapsulation/slow freezing led to greater post-thawed follicle quality than in the control group, as shown by follicle viability (66.9%±2.2% vs. 61.5%±3.1%), normal follicle morphology (62.2% ±2.1% vs. 55.2%±3.5%), and the relative band intensity of vascular endothelial growth factor protein phosphorylation (0.58±0.06 vs. 0.42±0.09). Experiment II demonstrated that hydrogel encapsulation promoted follicle survival and maintenance of follicle development regardless of the culture system when compared to fresh controls. Conclusion: These results provide a better understanding of the role of hydrogel encapsulation and culture systems in ovarian tissue cryopreservation and follicle quality outcomes using an animal model, paving the way for optimized approaches to human fertility preservation.

• International Journal of Computer Science & Network Security
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• 제24권3호
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• pp.125-134
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• 2024

The novel coronavirus 2019 is called COVID-19 has outspread swiftly worldwide. An early diagnosis is more important to control its quick spread. Medical imaging mechanics, chest calculated tomography or chest X-ray, are playing a vital character in the identification and testing of COVID-19 in this present epidemic. Chest X-ray is cost effective method for Covid-19 detection however the manual process of x-ray analysis is time consuming given that the number of infected individuals keep growing rapidly. For this reason, it is very important to develop an automated COVID-19 detection process to control this pandemic. In this study, we address the task of automatic detection of Covid-19 by using a popular deep learning model namely the VGG19 model. We used 1300 healthy and 1300 confirmed COVID-19 chest X-ray images in this experiment. We performed three experiments by freezing different blocks and layers of VGG19 and finally, we used a machine learning classifier SVM for detecting COVID-19. In every experiment, we used a five-fold cross-validation method to train and validated the model and finally achieved 98.1% overall classification accuracy. Experimental results show that our proposed method using the deep learning-based VGG19 model can be used as a tool to aid radiologists and play a crucial role in the timely diagnosis of Covid-19.

• ETRI Journal
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• 제35권1호
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• pp.27-34
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• 2013

This paper proposes a network-adaptive mechanism for HTTP-based video streaming over wireless/mobile networks. To provide adaptive video streaming over wireless/mobile networks, the proposed mechanism consists of a throughput estimation scheme in the time-variant wireless network environment and a video rate selection algorithm used to increase the streaming quality. The adaptive video streaming system with proposed modules is implemented using an open source multimedia framework and is validated over emulated wireless/mobile networks. The emulator helps to model and emulate network conditions based on data collected from actual experiments. The experiment results show that the proposed mechanism provides higher video quality than the existing system provides and a rate of video streaming almost void of freezing.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1996년도 추계학술대회
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• pp.281-285
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• 1996

Pulsatile swelling behaviors and their application to drug delivery system were studied by using interpenetrating polymer networks(IPN) hydrogels constructed with poly(vinyl alcohol) and poly(acrylic acid). The PVA/PAAc IPNs hydrogels were symthesized by UV irradiation tallowed by repetitive freezing and thawing method. These hydrogels showed pH and temperature sensitive swelling behaviors. From the release experiment, the release amount of model drug incorporated into these hydrogels showed pulsatile patterns. Permeability coefficients obtained by various solutes differed in response to changes of permeation conditions.

• International Journal of Naval Architecture and Ocean Engineering
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• 제12권1호
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• pp.157-167
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• 2020

The purpose of this study is to analyze the relationship between the occurrence of intermediate peak and time duration, and to conduct a review for the causes of the intermediate peak. In this test, ice impact tests were conducted using a bow side shell frame and ice specimen. A total of 70 samples were manufactured. Two types of ice specimen with relatively different surface conditions were used. The criterion for dividing the two types of ice specimen was the different exposure times to room temperature after freezing. This experiment was conducted for each parameter in order to reproduce the actual icebreaking situation. As a result of the analysis, the intermediate peak in the ice load signal have been found to be caused by mechanisms by which the inner surface of broken ice contact with hull immediately after the initial hitting point of ice has been broken.

• 한국해양공학회지
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• 제22권3호
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• pp.64-70
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• 2008

A full-scale field experiment is an important part in the design of ships and offshore structures. Full-scale tests in the ice-covered sea, however, are usually very expensive and difficult tasks. Model tests in a refrigerated ice tank may substitute this difficulty of full-scale field tests. One of the major tasks to perform proper model tests in an ice towing tank is to select a realistic material for model ice which shows correct similitude with natural sea ice. This study focuses on the testing material properties and the selection of model ice material which will be used in an ice model basin. The first Korean ice model basin will be constructed at the Maritime & Ocean Engineering Research Institute (MOERI) in 2009. With an application to the MOERI ice model basin, in this study the material properties of EG/AD/S model ice of IOT (Institute for Ocean Technology) Canada, were tested. Through comprehensive bending tests, the elastic modulus and the flexural strength of EG/AD/S model ice were evaluated and the results were compared with published test results from Canada. Instead of using an ice model basin, a cold room facility was used for making a model ice specimen. Since the cold room adopts a different freezing procedure to make model ice, the strength of the model ice specimen differs from the published test results. The reason for this difference is discussed and the future development for a making model ice is recommended.

• 정보과학회 논문지
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• 제43권7호
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• pp.763-772
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• 2016

다양한 센서가 부착된 스마트 폰의 보급으로 상황인지 어플리케이션 시장의 규모가 발달하고 있다. 하지만, 한정된 전력으로 인해 원활한 서비스를 제공받기는 어렵다. 상황인지 어플리케이션 관점에서 볼 때, 컨텍스트의 종류에 따라 필요한 센싱 정보가 다르기 때문에, 컨텍스트의 전이가 발생하면 필요한 센서들의 변화로 인해 센서 모듈들을 끄고 켜는 과정에서의 전력 소비가 크며, 정확한 센싱이 되지 않는 상황에서 과도한 센싱을 시도하게된다. 본 논문에서는 실내/실외 컨텍스트 전이에서 발생하는 전력 소모에 초점을 두고 해당 컨텍스트와 연관된 센서 활동을 모델링 한 뒤, 컨텍스트 전이가 일어나는 시점을 감지하여 전력 소모를 최소화할 수 있는 freezing 알고리즘을 적용하는 기법을 제안한다. 시중의 실내/실외 위치추적 어플리케이션을 이용하여 컨텍스트 전이가 발생하는 지점에서, 제안하는 기법의 유무에 따른 소비 전력 차이를 실측하였으며, 시중의 어플리케이션의 실제 구동 중 컨텍스트 전이과정에서의 전력 절감이 있었으며, 전체 시나리오에서 약 20%의 전력 절감 효과를 얻었다.

• 콘크리트학회논문집
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• 제15권4호
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• pp.529-540
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• 2003

최근 콘크리트 내구성설계에 관한 연구가 활발히 진행되고 있으며, 사용수명 예측이 핵심인 내구성 평가모델 개발이 그 좋은 예이다. 본 연구에서는 콘크리트 구조물의 잔존수명예측 모델을 개발하여 적정시기의 유지보수를 통한 경제적 구조물 사용을 목적으로 하였다. 육지 콘크리트 구조물인 저수지의 콘크리트 구조물 부분을 대상으로 전국 70개 지구를 선정하고, TG/DTA 법과 페놀프탈레인 지시약법으로 중성화를, pH메타법으로 pH 값을 측정하여 탄산칼슘함량 대비 사용연수, pH값, 콘크리트 피복 두께의 관계함수를 각각 유도한 후 가능한 최소의 자료측정으로 잔존수명을 예측할 수 있는 모델을 개발하였다. 개발된 잔존수명예측 모델은 탄산가스등의 고정변수에 의한 실내촉진실험 자료기반 모델과 달리 동결융해작용, 중성화, 철근 부식 등 복합적인 열화작용이 동시에 일어나는 현장의 환경적 영향을 받은 구조물에서 측정한 자료를 기반으로 개발되었다. 이러한 점에서 그 신뢰성을 높게 평가 받을 수 있을 것이며, 시설물 유지관리자에게 적정 보수보강 시점을 제공하여 경제적인 구조물 사용에 도움을 줄 수 있을 것으로 판단된다.

• 한국자동차공학회논문집
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• 제20권4호
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• pp.125-132
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• 2012

Urea-SCR system, which converts nitrogen oxides to nitrogen and water in the presence of a reducing agent, usually AdBlue urea solution, is known as one of the powerful NOx reduction systems for mobile as well as stationary applications. For its consistent and reliable operation in mobile applications, such various problems as transient injection, ammonia slip, and freezing in cold weather have to be resolved. In this work, therefore, numerical study on three-dimensional unsteady heating problems were analyzed to understand the melting and heat transfer characteristics such as urea liquid volume fraction, temperature profiles and generated natural convection behavior in urea solution by using the commercial software Fluent 6.3. After validating by comparing numerical and experimental data with pure gallium melting phenomena, numerical experiment for urea melting is conducted with three different coolant heating models named CH1, 2, and 3, respectively. Finally, it can be found that the CH3 model, in which more coolant is concentrated on the lower part of the urea tank, has relatively better melting capability than others in terms of urea quantity of $1{\ell}$ for start-up schedule.

• 대한기계학회논문집
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• 제18권12호
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• pp.3276-3286
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• 1994

In most direct contact liquid-liquid heat exchangers, oil or hydrocarbon with a density less than water is normally used as dispersed working fluid. The main difficulty that arises with this arrangement lies in the control of the interface at the top of the column. When it is connected with a solar collector which uses water as its working fluid, the main difficulties arise from the fact that the water can be frozen during winter time. In order to solve these problems and to demonstrate the technical feasibility of a direct contact liquid-liquid heat exchanger, liquids heavier than water with low freezing temperature has been utilized as dispersed phase liquids in a small laboratory scale model made of pyrex glass. In the present investigation, dimethyl phthalate(C/sub 6/H/sub 4/)COOCH/sub 3/)/sub 2/) and diethyl phthalate (C/sub 6/H/sub 4/(CO/sub 2/C/sub 2/H/sub 5/)/sub 2/) are utilized as heavy dispersed phase working fluids. The results of the present investigation the technical in the utilization of heavier dispersed working liquid in the spray-column liquid-liquid heat exchanger for a solar system. The overall average temperature difference along the column is found to be almost half of the initial temperature difference between the dispersed and the continuous phase. Despite the fact that the two phthalates tested in the experiment differ significantly in some of their physical properties, the volumetric heat transfer coefficients in terms of dispersed fluid superficial velocities were found to be similar for both phthalates tested.