• Title/Summary/Keyword: Free-floating

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Endogenous Sphingoid Bases Accumulation by FTY720 in $LLC-PK_1$ Cells (FTY720에 의한 $LLC-PK_1$ 세포내 sphingoid bases의 축적)

  • 이우진;이용문
    • YAKHAK HOEJI
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    • v.43 no.1
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    • pp.85-90
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    • 1999
  • FTY720, a novel immunosuppressant, elevated the level of endogenous sphingoid bases in a dose-dependent manner within 3 hr in $LLC-PK_1$ cells. The relative molar ratio of sphingoid bases expressed as sphingosine/sphinganine (SPN/SPA), a biomarker of altered sphingolipid biosynthesis, in $10{\;}{\mu}M$ of FTY720 showed tow-fold increase as compared with the one in control culture. FTY720 under the serum-free medium condition increased only cytosolic free sphingosine concentration, not sphinganine concentration in a time-dependent manner over the 8 hr incubation under the same condition as in serum free cultures, the SPN/SPA ratio began to fluctuate and the number of floating cells as an indicator of cytotoxicity was increased 8 hr after the addition of FTY720 to cultured cells. These results suggest that the process of FTY720-induced cell death in $LLC-PK_1$ cells.

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Development of cryogenic free-piston reciprocating expander utilizing phase controller

  • Cha, Jeongmin;Park, Jiho;Kim, Kyungjoong;Jeong, Sangkwon
    • Progress in Superconductivity and Cryogenics
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    • v.18 no.2
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    • pp.42-47
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    • 2016
  • A free-piston reciprocating expander is a device which operates without any mechanical linkage to a stationary part. Since the motion of the floating piston is only controlled by the pressure difference at two ends of the piston, this kind of expander may indispensably require a sophisticated active control system equipped with multiple valves and reservoirs. In this paper, we have suggested a novel design that can further reduce complexity of the previously developed cryogenic free-piston expander configuration. It is a simple replacement of both multiple valves and reservoirs by a combination of an orifice valve and a reservoir. The functional characteristic of the integrated orifice-reservoir configuration is similar to that of a phase controller applied in a pulse tube refrigerator so that we designate the one as a phase controller. Depending on the orifice valve size in the phase controller, the different PV work which affects the expander performance is generated. The numerical model of this unique free-piston reciprocating expander utilizing a phase controller is established to understand and analyze quantitatively the performance variation of the expander under different valve timing and orifice valve size. The room temperature experiments are carried out to examine the performance of this newly developed cryogenic expander.

Spatial Distribution Pattern of Cladoceran Community in Accordance with Microhabitat Types (미소서식처 유형별 지각류 (Cladocerans)의 분포 특성)

  • Jong-Yun Choi
    • Korean Journal of Environment and Ecology
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    • v.38 no.3
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    • pp.324-337
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    • 2024
  • Aquatic macrophytes are important factors in determining species diversity and abundance of cladocerans, but the effects of cladocerans on plant species composition or structure have not been fully considered. In South Korea, wetlands and reservoirs that are prone to covering aquatic macrophytes are scattered across the country, so it is necessary to consider on aquatic macrophytes study, when aquatic animals including cladoceran were studied. in this study, the species and abundance of cladocerans community in six microhabitat types are investigated, and based on these results, habitat conservation and efficient management are suggested. The high species numbers and abundance of cladocerans communities were found in mixed plant communities consisting of free-floating, floating-leaved, and submerged plants. The inclusion of submerged plants in plant communities contributes significantly to the complexity of habitat structures, and may increase species and abundance of cladocenran communities. This can be compared to a plant community consisting only of free-floating and floating-leaved plants in the absence of submerged plants, thereby identifying the efficiency of submerged plants. In the mixed plant communities, species diversity was the highest due to the emergence of cladoceran species (Graptoleveris testudinaria, Ilyocryptus spinifer, and Leydigia acanthococcides) absent from other plant communities. The gradual increase in the biomass (g) of submerged plants in the mixed plant communities significantly increased the species numbers and abundance of cladoceran communities (p<0.05). This is strong evidence that the increase of submerged plants in mixed plant communities has a positive effect on efficiency as a habitat for cladocerans. Although submeged plants do not contribute significantly to their landscape/aesthetic value because they are submerged in water, they have the effect of increasing species diversity in terms of biology, so they should be considered important when creating/restoring wetlands.

A case of Free-floating Left Atrial Ball Thrombus in Mitral Stenosis (승모판 협착증과 동반된 자유롭게 부유하는 좌심방 구형혈전 1례)

  • Kim, Young-Jin;Lee, Tea-Il;Choi, Kyo-Won;Kang, Seung-Ho;Sin, Dong-Gu;Kim, Young-Jo;Shim, Bong-Sup;Lee, Hyun-Woo;Hong, Eun-Pyo;Lee, Dong-Hyup;Lee, Jung-Cheul;Han, Sung-Sae
    • Journal of Yeungnam Medical Science
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    • v.10 no.1
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    • pp.237-244
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    • 1993
  • A free-floating ball thrombus in the left atrium is a rare complication of the mitral valvular disease. A 53-year-old man was admitted for pain and paresthesia on both legs. On admission he had auscultatory sign of mitral stenosis and mitral regurgitation, and the roentgenogram of his chest revealed a slight pulmonary venous congestion, enlargement of the pulmonary conus and cardiomegaly. Laboratory findings including complete blood counts, coagulation studies and blood chemistry were normal. An echocardiographic examination revealed a mitral stenosis and a free-floating ball thrombus in the left atrium. We performed the emergent open heart surgery for removal of the ball thrombus and mitral replacement successfully with Duromedics 29 mm valve. The size of thrombus was $39{\times}32{\times}30$ mm.

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A 3-Dimentional Radiation Diffraction Problem Analysis by B-Spline Higher-Order Panel Method

  • Kim Gun-Do;Lee Chang-Sup
    • Journal of Ship and Ocean Technology
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    • v.10 no.1
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    • pp.10-26
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    • 2006
  • The radiation problem for oscillating bodies on the free surface has been formulated by the over-determined Green integral equation, where the boundary condition on the free surface is satisfied by adopting the Kelvin-type Green function and the irregular frequencies are removed by placing additional control points on the free surface surrounded by the body. The B-Spline based higher order panel method is then applied to solve the problem numerically. Because both the body geometry and the potential on the body surface are represented by the B-Splines, that is in polynomials of space parameters, the unknown potential can be determined accurately to the order desired above the constant value. In addition, the potential expressed in B-Spline can be differentiated analytically to get the velocity on the surface without introducing any numerical error. Sample computations are performed for a semispherical body and a rectangular box floating on the free surface for six-degrees of freedom motions. The added mass and damping coefficients are compared with those by the already-validated constant panel method of the same formulation showing strikingly good agreements.

Element-Free Galerkin Method for the Analysis of Diffraction and Radiation Problems of Floating Breakwaters (무요소절점법을 이용한 부유식 구조물의 회절 및 방사문제 해석)

  • Lee, Jeongwoo;Cho, Woncheol
    • Proceedings of the Korea Water Resources Association Conference
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    • 2004.05b
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    • pp.1001-1006
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    • 2004
  • 본 연구에서는 요소를 사용하지 않고 절점들만을 이용하여 해석이 가능한 수치기법인 무요소절점법(element-free Galerkin method)의 개념을 선형파의 회절 및 방사문제에 적용하는 방법에 대해 연구하였다. 파동장에 놓인 부유식 구조물에 의한 연직 2차원 경계치 문제를 해석 대상으로 하였고, 파랑과 구조물의 상호작용을 해석함에 있어 구조물에 작용하는 동유체력과 이로 인한 구조물의 동적응답을 계산하기 위해서 무요소절점법을 이용하였다. 무요소절점법의 수식화과정을 체계적으로 정리하였으며, 무요소절점법의 타당성 및 적용성을 입증하기 위해서 직사자형 부유체에 내한 수치해석을 실시하여 타 논문의 결과와 비교하였다. 또한 해의 정확도에 직접적으로 영향을 미치는 절점간격과 파수와의 관계에 대한 기준 설정을 위한 수치실험도 수행하였다.

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Exact Solution on the Anti-symmetric Responses of Ships having Uniform Sectional Properties with Hydro-elasticity (균일단면 선박의 유탄성 수평응답에 대한 해석해)

  • ;;A. Korobkin
    • Journal of the Society of Naval Architects of Korea
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    • v.41 no.4
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    • pp.45-52
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    • 2004
  • Exact solution on the anti-symmetric response of ships having uniform sectional properties in waves is derived. Boundary value problem consisted of Timoshenko beam equation and free-free end condition is solved analytically. The responses are assumed as linear and wave loads are calculated by using strip method. Horizontal bending moment, shear force and torsional moment are calculated. The developed analysis model is used for the benchmark test of the numerical codes in this problem. Also the application on the preliminary design of barge-like ships and VLFS (Very Large Floating Structure) is expected

Exact Solution on the Vertical Hydro-elastic Responses of Ships having Uniform Sectional Properties (균일단면 선박의 유탄성 수직응답에 대한 해석해)

  • Park, In-Kyu;Jung, Jong-Jin;A. Korobkin
    • Journal of the Society of Naval Architects of Korea
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    • v.41 no.2
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    • pp.47-54
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    • 2004
  • Exact solution on the vertical responses of ships having uniform sectional properties in waves is derived. Boundary value problem consisted of Timoshenko beam equation and free-free end condition is solved analytically. The responses are assumed as linear and wave loads are calculated by using strip method. Vertical bending moment, shear force and deflection are calculated. The developed analysis model is used for the benchmark test of the numerical codes in this problem. Also the application on the preliminary design of barge-like ships and VLFS (Very Large Floating Structure) is expected.

Flora, Actual Vegetation Map, and Primary Production of the Vascular Hydrophytes and Hygrophytes in the Upo Wetland (우포늪에서 수생 및 습생 관속식물의 식물상, 현존식생도 및 1차 생산)

  • Kang, Min-jeong;Kim, Cheol-Soo;Oh, Kyung-hwan
    • Journal of Wetlands Research
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    • v.9 no.2
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    • pp.45-55
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    • 2007
  • Flora, actual vegetation map, distribution area by the life form, primary productivity and annual primary production by the vascular hydrophytes and hygrophytes were investigated in the Upo wetland, Changnyeong-gun, Gyeongsangnam-do, Korea from May 2005 to March 2006. The flora of Upo, Mokpo, Sajipo, Jokjibyeol, Topyeongcheon upstream, and Topyeongcheon downstream were composed of 263, 233, 244, 182, 190, and 178 taxa, respectively. The flora of total study area was 85 families, 224 genera, 287 species, 42 varieties, 4 form, or total 333 taxa. Among them, hydrophytes, hygrophytes, and others were 38, 108, and 187 taxa, respectively. The life form of the vascular hydrophytes was classified as 20 taxa of emergent plants, 6 taxa of floating-leaved plants, 5 taxa of free-floating plants, and 7 taxa of submersed plants, respectively. There were 27 plant communities including pure population, mixed population, and etc. It is also found that Trapa japonica-Ceratophyllum demersum community occupies 60.64 ha, the largest area, and Salvinia natans-Ceratophyllum demersum community 32.91 ha, Zizania latifolia community 30.05 ha, and that the area of free-floating plants was the largest as 172.6 ha(47.9%) on the basis of life form. Total annual primary production of the vascular hydrophytes and hygrophytes was 1,383.3ton. That of the emergent hydrophytes was the most as 564.1 ton(40.8%), and those of the free-floating, floating-leaved, and the submersed were 484.1 ton(34.9%), 146.7 ton(10.6%), and 1.3 ton(0.5%), respectively, and the hygrophytes was 182.1 ton(13.2%). Since most plant species are fairly adapted to the present marsh environment, bad influences and change of species composition are expected by the artificial influences on the wetland such as fragmentation, reclamation, and introduction of the exotic species. Therefore, schemes and counterplans for the conservation and preservation of the marsh are demanded.

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Hydroelastic Responses for a VLFS close to a Breakwater by the Velocity Potential Continuation and Singularity Distribution Method (속도포텐셜접속법과 특이점분포법에 의한 방파제에 근접한 부유식 해상공항에 대한 유탄성 응답 해석)

  • Ho-Young Lee;Young-Ki Kwak;Jong-Hwan Park
    • Journal of the Society of Naval Architects of Korea
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    • v.39 no.2
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    • pp.11-18
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    • 2002
  • In this paper, the method calculating hydroelastic responses of very large floating structure close to a breakwater in waves is presented. The source-dipole distribution method is used to calculate the generalized radiation problem considering breakwater effects and the diffraction problem is analyzed by using the source-dipole distribution andvelocity potential continuation method. The response of a VLFS is approximated by anexpansion in terms of a free-free beam. Calculated model is a VLFS with 1000m in length in a sea with a straight breakwater. The vertical displacements and bonding moments around a VLFS are calculated by variations for distance between a VLFS and a breakwater and incident wave angle to know the effect of a breakwater.