• 제목/요약/키워드: Free-Will

검색결과 2,045건 처리시간 0.027초

Hydrophobicity of Amino Acids in Protein Context

  • Cho, Hanul;Chong, Song-Ho;Ham, Sihyun
    • EDISON SW 활용 경진대회 논문집
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    • 제3회(2014년)
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    • pp.103-113
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    • 2014
  • Hydrophobicity is the key concept to understand the role of water in protein folding, protein self-assembly, and protein-ligand interaction. Conventionally, hydrophobicity of amino acids in a protein has been argued based on hydrophobicity scales determined for individual free amino acids, assuming that those scales are unaltered when amino acids are embedded in a protein. Here, we investigate how the hydrophobicity of constituent amino acids depends on the protein context, in particular, on the total charge and secondary structures of a protein. To this end, we compute and analyze the hydration free energy - free energy change upon hydration quantifying the hydrophobicity - of three short proteins based on the integral-equation theory of liquids. We find that the hydration free energy of charged amino acids is significantly affected by the protein total charge and exhibits contrasting behavior depending on the protein net charge being positive or negative. We also observe that amino acids in the central ${\beta}$-strand sandwiched by ${\beta}$-sheets display more enhanced hydrophobicity than free amino acids, whereas those in the ${\alpha}$-helix do not clearly show such a tendency. Our results provide novel insights into the hydrophobicity of amino acids, and will be valuable for rationalizing and predicting the strength of water-mediated interaction involved in the biological activity of proteins.

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자유표면에 작용하는 와동 현상에 대한 연구 (A Study on Vortex Pair Interaction with Fluid Free Surface)

  • 손권;류홍곤;김경훈;김석우
    • 한국가시화정보학회:학술대회논문집
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    • 한국가시화정보학회 2002년도 추계학술대회 논문집
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    • pp.67-72
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    • 2002
  • Today, the research to examine a fact that interaction between the air and the fluid free surface affects the steady state flow and air. We proved the interaction between vortex pairs and free surface on each condition that is created by the end of delta wings. another purpose of this study is to investigate the effect of surface active material which can change the surface tension and we must consider when we refer to turbulent flow on surface tension. therefore, this research examined the growth process of vortex pairs on condition of clean, contaminated free surface and wall after we made vortex pairs through counter rotating flaps. The results of this study suggest that vortex pairs in clean free surface rise safely but the vortex pairs in contaminated free surface and rigid, no slip is made secondary vortex or rebounding. However the secondary vortex in rigid, no slip is stronger than before, and we can find the vortex shape which roll up more completely. However, these will disappear by the effect of wall.

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Free vibration analysis of power-law and sigmoidal sandwich FG plates using refined zigzag theory

  • Aman Garg;Simmi Gupta;Hanuman D. Chalak;Mohamed-Ouejdi Belarbi;Abdelouahed Tounsi;Li Li;A.M. Zenkour
    • Advances in materials Research
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    • 제12권1호
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    • pp.43-65
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    • 2023
  • Free vibration analysis of power law and sigmoidal sandwich plates made up of functionally graded materials (FGMs) has been carried out using finite element based higher-order zigzag theory. The present model satisfies all-important conditions such as transverse shear stress-free conditions at the plate's top and bottom surface along with continuity condition for transverse stresses at the interface. A Nine-noded C0 finite element having eleven degrees of freedom per node is used during the study. The present model is free from the requirement of any penalty function or post-processing technique and hence is computationally efficient. The present model's effectiveness is demonstrated by comparing the present results with available results in the literature. Several new results have been proposed in the present work, which will serve as a benchmark for future works. It has been observed that the material variation law, power-law exponent, skew angle, and boundary condition of the plate widely determines the free vibration behavior of sandwich functionally graded (FG) plate.

Theoretical Results for a Dipole Plasmonic Mode Based on a Forced Damped Harmonic Oscillator Model

  • Tongtong Hao;Quanshui Li
    • Current Optics and Photonics
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    • 제7권4호
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    • pp.449-456
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    • 2023
  • The localized surface-plasmon resonance has drawn great attention, due to its unique optical properties. In this work a general theoretical description of the dipole mode is proposed, using the forced damped harmonic oscillator model of free charges in an ellipsoid. The restoring force and driving force are derived in the quasistatic approximation under general conditions. In this model, metal is regarded as composed of free charges and bound charges. The bound charges form the dielectric background which has a dielectric function. Those free charges undergo a collective motion in the dielectric background under the driving force. The response of free charges will not be included in the dielectric function like the Drude model. The extinction and scattering cross sections as well as the damping coefficient from our model are verified to be consistent with those based on the Drude model. We introduce size effects and modify the restoring and driving forces by adding the dynamic depolarization factor and the radiation damping term to the depolarization factor. This model provides an intuitive physical picture as well as a simple theoretical description of the dipole mode of the localized surface-plasmon resonance based on free-charge collective motion.

ON THE FREE AUTOMATA AND TENSOR PRODUCT

  • Park, Chin-Hong
    • Journal of applied mathematics & informatics
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    • 제9권2호
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    • pp.705-716
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    • 2002
  • In this paper we shall introduce the algebraic structure of a tensor product for arbitrarily given automata, giving a defintion of the tensor product for automata. We introduce and study that for any set X there always exists a free automaton on X. The existence of a tensor product for automata will be investigated in the same way like modules do.

A SHAPE OPTIMIZATION METHOD USING COMPLIANT FORMULATION ASSOCIATED WITH THE 2D STOKES CHANNEL FLOWS

  • Kim, Hongchul
    • Korean Journal of Mathematics
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    • 제16권1호
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    • pp.25-40
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    • 2008
  • We are concerned with a free boundary problem for the 2D Stokes channel flows, which determines the profile of the wing for the channel, so that the given traction force is to be distributed along the wing of the channel. Using the domain embedding technique, the free boundary problem is transferred into the shape optimization problem through the compliant formulation by releasing the traction condition along the variable boundary. The justification of the formulation will be discussed.

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2차원 광학 위치센서에 관한 연구 (A study on the rotation-free optical position sensor in two dimensional tracking)

  • 오준호;제우성;임준영
    • 제어로봇시스템학회:학술대회논문집
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    • 제어로봇시스템학회 1988년도 한국자동제어학술회의논문집(국내학술편); 한국전력공사연수원, 서울; 21-22 Oct. 1988
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    • pp.448-451
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    • 1988
  • This paper deals with the rotation-free optical sensor which will be used for two dimensional robot tracking. This sensor consists of position sensing device and coordinate transformation unit which transform the sensor coordinate into base coordinate. A new coordinate transformation algorithm which use analog signal is presented, and an analog circuit based on this algorithm is constructed. To prove the rightness of this algorithm, same experiments are carried out. And the performance, of this sensor is investigated.

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A NOTE ON KADIRI'S EXPLICIT ZERO FREE REGION FOR RIEMANN ZETA FUNCTION

  • Jang, Woo-Jin;Kwon, Soun-Hi
    • 대한수학회지
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    • 제51권6호
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    • pp.1291-1304
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    • 2014
  • In 2005 Kadiri proved that the Riemann zeta function ${\zeta}(s)$ does not vanish in the region $$Re(s){\geq}1-\frac{1}{R_0\;{\log}\;{\mid}Im(s){\mid}},\;{\mid}Im(s){\mid}{\geq}2$$ with $R_0=5.69693$. In this paper we will show that $R_0$ can be taken $R_0=5.68371$ using Kadiri's method together with Platt's numerical verification of Riemann Hypothesis.

UNIT GROUPS OF QUOTIENT RINGS OF INTEGERS IN SOME CUBIC FIELDS

  • Harnchoowong, Ajchara;Ponrod, Pitchayatak
    • 대한수학회논문집
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    • 제32권4호
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    • pp.789-803
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    • 2017
  • Let $K={\mathbb{Q}}({\alpha})$ be a cubic field where ${\alpha}$ is an algebraic integer such that $disc_K({\alpha})$ is square-free. In this paper we will classify the structure of the unit group of the quotient ring ${\mathcal{O}}_K/A$ for each non-zero ideal A of ${\mathcal{O}}_K$.