• 제목/요약/키워드: Free T4

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울트라마라톤이 뇌하수체 전엽 및 갑상선 호르몬에 미치는 영향 (Effect of Ultramarathon on the Anterior Pituitary and Thyroid Hormones)

  • 신경아;김영주
    • 대한스포츠의학회지
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    • 제36권4호
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    • pp.214-220
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    • 2018
  • Purpose: The purpose of this research is to study changes in pituitary hormone in anterior lobe and thyroid hormone before, after, and during recovery time in severe 100 km ultramarathon. Methods: Healthy middle-aged runners (age, $52.0{\pm}4.8$ years) participated in the test. Grade exercise test is done, and then blood is taken from those participants before and after completing 100 km ultramarathon at the intervals of 24 hours (1 day), 72 hours (3 days), and 120 hours (5 days) to analyze their luteinizing hormone (LH), follicle-stimulating hormone (FSH), thyroid stimulating hormone (TSH), triiodothyronine (T3), thyroxine (T4), and free thyroxine (Free T4). Results: For LH, it decreased more significantly at 100 km than pre-race. However, after 1 day result increased more than that of 100 km. At 3 days, it was significantly higher than pre-race and 100 km, recovering at 5 days. In terms of FSH, it decreased at 100 km, 1 day, and 3 days more than pre-race but recovered at 5 days. TSH was higher at 1 day and 5 days compared to pre-race. T3 was only higher at 100 km than pre-race. T4 was higher till 5 days at 100 km than pre-race. Free T4 increased more significantly at 100 km than pre-race. Conclusion: In terms of severe long distance running, LH and FSH which belong to hormone from anterior lobe as well as T3, T4, and Free T4 which belong to thyroid hormone showed their variation within the standard range. However, TSH showed abnormal increase from enhanced concentration of blood after marathon becoming hyper-activation even during the recovery period.

Effects of Mixed Application of Chemical Fertilizer and Liquid Swine Manure on Agronomic Characteristics, Yield and Feed Value of Sorghum × Sudangrass Hybrid for Silage in Paddy Field Cultivation

  • Hwang, Joo Hwan;Lee, Sang Moo
    • 한국초지조사료학회지
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    • 제34권3호
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    • pp.155-162
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    • 2014
  • This study was conducted to investigate the influence of the mixed application of chemical fertilizer (CF) and liquid swine manure (LSM) on the agronomic characteristics, dry matter yield, amino acids, minerals, and free sugars in cultivating Sorghum ${\times}$ Sudangrass hybrid (SSH) on paddy soil. The field experiment was designed in a randomized block design with three replications and consisted of CF 100% (C), CF 70% + LSM 30% (T1), CF 50% + LSM 50% (T2), CF 30% + LSM 70% (T3), and LSM 100% treatment (T4). The application of LSM was based solely on the nitrogen. Plant length, leaf length, leaf width and number of leaf were significantly higher in T4 (p<0.05), but stem diameter did not show significant differences among treatments. Stem hardness increased significantly (p<0.05) as the LSM application rate decreased, but sugar degree decreased significantly (p<0.05) as the LSM application rate decreased. Fresh yield, dry matter yield and TDN yield were the highest in T4, whereas the lowest in T2 (p<0.05). Crude protein, crude fat and crude ash were the highest in C, T4 and T2, respectively (p<0.05). However, NDF and ADF did not show significant difference among treatments. Crude fiber decreased significantly (p<0.05) as the LSM application rate increased. The total mineral content was decreased significantly (p<0.05) as the LSM application rate increased. Total amino acid content was higher in the order of T1> C> T3> T4> T2 (p<0.05). Free sugar content increased significantly (p<0.05) as the LSM application rate increased. The analysis of all the above results suggests that the application of liquid swine manure is very effective, considering the yield performance and the content of sugar degree and free sugar. In addition, liquid swine manure may be possible to grow Sorghum ${\times}$ Sudangrass hybrid without chemical fertilizer.

IrMn 스핀필터 스페큘라 스핀밸브의 자기저항 특성 (Magnetoresistance of IrMn-Based Spin Filter Specular Spin Valves)

  • 황재연;이장로
    • 한국자기학회지
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    • 제14권6호
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    • pp.236-239
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    • 2004
  • 미소 자유자성층에 인접한 스핀필터층 (SFL; spin filter layer)을 갖는 Ta3/NiFe2/IrMn7/CoFe1/(NOL1)/CoFe2/Cu 1.8/CoFe( $T_{f}$)/Cu( $t_{SF}$ )/(NOL2)/Ta3.5 (두께단위 nm) 구조의 스페큘라 스핀밸브 (SSV; specular spin valve)를 마그네트론 스퍼터링 장치를 사용하여 제작하였다. 반강자성체 I $r_{22}$M $n_{78}$을 속박층으로 한 스핀필터 스페큘라 스핀밸브 (SFSSV; spin filter specular spin valve) 박막에 대하여 자유자성층의 두께 ( $t_{F}$)와 SFL의 두께 ( $t_{SF}$ )가 각각 1.5nm일 때 극대 자기저항 (MR; magnetoresistance)비 11.9%를 얻었으며, $t_{SF}$ 가 1.0nm으로 감소하여도 11%이상의 MR비를 유지하였다. 이것은 나노산화층 (NOL; nano-oxide layer)에 의한 스페큘라 전자와 SFL에 의한 전류분류효과의 증가 때문이다. 또한, 자유자성층과 피속박층 사이의 층간결합장 ( $H_{int}$; interlayer coupling field)은 RKKY력과 정자기결합력으로 설명할 수 있다. 자유자성층의 보자력 ( $H_{cf}$ ; coercivity of the free layer)은 기존의 스핀밸브 (TSV; traditional spin valve)에 비해 현저히 감소했으며, $t_{F}$가 1nm에서 4nm로 변하여도 4 Oe이하의 값을 유지하였다. 따라서 SFL의 삽입으로 자유자성층의 연자성 특성을 떨어뜨리지 않으면서 자유자성층 두께의 감소와 MR비의 향상을 가능하게 하였다.

An existence of solutions for an infinte diffusion constant

  • Ham, Yoon-Mee
    • 대한수학회보
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    • 제33권4호
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    • pp.631-638
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    • 1996
  • The parabolic free boundary problem with Puschino dynamics is given by (see in [3]) $$ (1) { \upsilon_t = D\upsilon_{xx} - (c_1 + b)\upsilon + c_1 H(x - s(t)) for (x,t) \in \Omega^- \cup \Omega^+, { \upsilon_x(0,t) = 0 = \upsilon_x(1,t) for t > 0, { \upsilon(x,0) = \upsilon_0(x) for 0 \leq x \leq 1, { \tau\frac{dt}{ds} = C)\upsilon(s(t),t)) for t > 0, { s(0) = s_0, 0 < s_0 < 1, $$ where $\upsilon(x,t)$ and $\upsilon_x(x,t)$ are assumed continuous in $\Omega = (0,1) \times (0, \infty)$.

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운동강도의 차이가 안정시대사량 및 에너지 소비량에 미치는 영향 (Effects of Changes in Exercise Intensity on Resting Metabolic Rate (RMR) and Energy Expenditure in Young Men)

  • 곽이섭;진영완;박찬호
    • 생명과학회지
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    • 제15권3호
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    • pp.352-358
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    • 2005
  • The purpose of this study was to examine the effect of various exercise intensity on Resting Metabolic Rate (RMR), excess post exercise energy expenditure (EPEE), and thyroid hormonal changes in trained (TR) and untrained (UT) people. The subject of the present study were divided into two groups and four periods: trained (TR; n=6) and untrained (UT; n=6) group. And the periods were divided as follows; Resting (R), Maximal (M), High intensity (H), and Low intensity (L). The percent body fat and RMR of all subjects were measured at every periods. The RMR was measured early in the morning following a 12-hour fast using MMX3B gas analyzer and blood sample were collected from the anticubital vein to investigate thyroid hormonal (T3, T4, Free T3, Free T4, & TSH) changes. All the RMR values were expressed as absolute value/BSA $(kcal/d/m^2)$. And We also analyzed mean energy expenditure for 30 minutes during and after different intensity exercise. There was significant difference in RMR among different intensity of exercise. in TR (p < .05) not in the UT group. however, there was no significant different percent body fat in TR and in UT group. In the energy expenditure, there was significant different between TR and UT in HEE (high intensity exercise energy expenditure), LEE (low intensity exercise energy expenditure), HEEPE (high intensity exercise energy expenditure post exercise) & LEEPE (low intensity exercise expenditure post exercise). In the hormonal level, there was significant different in T4 level in the TR group at H period and in T4, Free T3, & Free T4 levels in TR group at L period, however there was no significant different in the UT group. The present cross-sectional study was design to investigate the relationship between exercise intensity and RMR. The focus of this investigation was to compare RMR in aerobically trained (TR) and untrained (VI). The relationship among RMR, exercise intensity and percent body fat would best be investigated using MMX3B and body composition analyzer. Each subject completed measurement of percent body fat, RMR, hormone in the period of maximal oxygen uptake exercise (M), high intensity exercise (H), and low intensity exercise (L). From the results, Low intensity of exercise (L), there was a trend for an increased RMR (kcal/day) in the TR not for the UT. This is best explained not by the reduced percent body fat but by the highly induced energy expenditure (during exercise and post exercise energy expenditure) and increased T4, Free T3, and Free T4 hormonal levels in the low intensity exercise for the TR group.

Effects of Mixed Application of Chemical Fertilizer and Liquid Swine Manure on Agronomic Characteristics, Yield and Feed Value of Corn Hybrid for Silage in Paddy Field Cultivation

  • Lee, Sang Moo
    • 한국초지조사료학회지
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    • 제32권4호
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    • pp.369-378
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    • 2012
  • This study was performed out to investigate the influence of the mixed application of chemical fertilizer (CF) and liquid swine manure (LSM) on the growth characteristics, dry matter yield, amino acids, minerals, and free sugars in cultivating silage corn on paddy soils. The field experiment was designed in a randomized block design of 3 repetitions with CF 100% treatment (C), CF 70% + LSM 30% treatment (T1), CF 50% + LSM 50% treatment (T2), CF 30% + LSM 70% treatment (T3), and LSM 100% treatment (T4). At this time, the application of LSM was based solely on the nitrogen. Ear length, ear circle, stem diameter, and stem hardness of the silage corn did not show significant differences between treatments. Fresh yield, dry matter yield and TDN yield were highest in T3, whereas the lowest in C treatment (p<0.05). Crude protein, crude fat, and crude ash content were significantly higher in T1, C, and T4 treatment, respectively (p<0.05). However, NDF, ADF and crude fiber content did not show significant difference between treatments. The total mineral content decreased significantly (p<0.05) as the LSM application rate increased. Total composition amino acid content was higher in the order of T1 > T2 > C > T4 > T3 treatment (p<0.05). Free sugar content was higher in the order of T1 > T3 > T4 > T2 > C treatment (p<0.05). Based on the above results, suggests that the mixed application of chemical fertilizer 30~50% and LSM 50~70% (T2 and T3) is the most effective, considering the yield performance and the content of sugar degree and free sugar affecting silage.

흰목이와 흑목이 버섯의 다당추출 및 유리라디칼 소거활성 비교 (Polysaccharide Extraction and Comparison of Free Radical Scavenging Activities from Tremella fuciformis and Auricularia auricula Fruit Body)

  • 김현민;허원;이신영
    • 산업식품공학
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    • 제15권1호
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    • pp.6-14
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    • 2011
  • The polysaccharides from fruit body of Auricularia auricula and Tremella fuciformis were extracted using hot water, and partially purified through ethanol precipitation and dialysis. Free radical scavenging activities of the crude and purified polysaccharides were examined and compared each other. Free radical scavenging activities of the partially purified polysaccharides were higher than those of crude polysaccharides. DPPH free radical, ABTS radical and SOD-like activities of partially purified polysaccharide at 1 mg/mL of concentration from A. auricula were 61.7, 9.6 and 38.9%, respectively, while those of T. fuciformis were 9.6, 5.7 and 15.3%, respectively. Results of site and non-site specific hydroxyl radical scavenging activities indicated that the partially purified polysaccharide fractions from A. auricula and T. fuciformis exhibited the hydroxyl radical scavenging effect by hydrogen donating ability and iron ion chelating ability. Also, reducing powers of A. auricula and T. fuciformis were 77.1 and 14.7% of BHT (0.1%) as standard, respectively. It was suggested that antioxidant activities of A. auricula were about 1.4~6.4 times higher than those of T. fuciformis due to different levels of polyphenol content.

선천성 갑상선기능저하증에 대한 신생아 선별검사의 재평가 (Reevaluation of the Neonatal Screening Test for Congenital Hypothyroidism)

  • 강소영;장영표;유지숙
    • Clinical and Experimental Pediatrics
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    • 제48권4호
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    • pp.387-394
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    • 2005
  • 목 적 : 선천성 갑상선기능저하증에 대한 신생아 선별검사결과의 이상빈도는 실제 임상적으로 진단되는 질환의 발생빈도보다 훨씬 높다. 본원에서 시행되는 선천성 갑상선기능저하증에 대한 신생아 선별검사의 위양성률과 소환율을 알아보고 재태기간과 출생체중에 따른 검사결과치를 비교하여 각각의 결과에 따라 cut-off value를 재평가함으로써 임상에서 신생아 선별검사의 결과를 해석하고 질환을 진단하는데 도움을 주고자 하였다. 방 법 : 2000년 5월부터 2003년 1월까지 단국대학교병원에서 출생한 2,133명의 신생아를 대상으로 정상분만의 경우 생후 3일째, 제왕절개인 경우 생후 5일째, 신생아중환자실에 입원한 미숙아인 경우 생후 $14.3{\pm}12.4$일(5-79일) 이내에 신생아의 발뒤꿈치를 천자하여 모세혈을 검사용 채혈지에 묻혀 갑상선자극호르몬과 유리 $T_4$를 효소면역법으로 분석하였고 각각의 기존참고치인 $20{\mu}IU/mL$ 이상, 1 ng/dL 미만일 경우 소아과 외래로 불러 재검하였으며 이때 이학적 검사 및 주산기적 병력, 약물력, 모체질환 등의 여부를 조사하였고 혈청을 이용해 면역형광법에 의한 갑상선기능검사를 시행하였다. 결 과 : 1) 다른 질병이 없었던 1,749명의 갑상선자극호르몬과 유리 $T_4$의 평균${\pm}$표준편차는 각각 $9.01{\pm}5.82{\mu}IU/mL$, $1.99{\pm}0.90ng/dL$이었고 성별, 분만형태, 아프가 점수에 따른 차이는 없었다. 2) 재태연령과 출생체중에 따라 갑상선자극호르몬의 수치는 의미있는 차이가 없었고 유리 $T_4$의 수치는 의미있는 차이가 있었다(P<0.01). 3) 다른 질병이 있었던 384명의 갑상선자극호르몬과 유리 $T_4$의 평균${\pm}$표준편차는 각각 $9.17{\pm}7.22{\mu}IU/mL$, $1.52{\pm}0.75ng/dL$이었고, 건강한 신생아와 비교시 갑상선자극호르몬의 수치는 의미있는 차이가 없었고 유리 $T_4$의 수치는 의미있는 차이가 있었다(P<0.01). 4) 신생아 선별검사에서 131명이 소환되었고 재소환율은 7.48%이었으며, 이중 추적관찰이 가능했던 87명의 갑상선기능이 정상화된 기간은 출생체중과 의미있는 관계는 없었고, 출생주수와는 음의 상관관계를 보였다(P=0.042, Pearson 상관계수 -0.177). 5) 신생아 선별검사에서 재소환되어 선천성 갑상선기능저하증을 진단받은 환아는 모두 4명으로 2명은 갑상선자극호르몬 수치만 $20{\mu}IU/mL$ 이상이었고 2명은 유리 $T_4$ 수치만 1 ng/dL 미만이었으며, 3명은 건강한 신생아에, 1명은 질병이 있었던 군에 속했다. 6) Cut-off value를 본 연구에서 시행되었던 기준인 갑상선 자극호르몬이 $20{\mu}IU/mL$ 이상이거나 또는 유리 $T_4\;1\;ng/dL$ 미만인 경우 소환율, 양성예측률, 민감도, 특이도는 각각 7.48%, 2.29%, 75%, 92.6%이었다. 갑상선자극호르몬이 $20{\mu}IU/mL$ 이상이거나 유리 $T_4\;0.64\;ng/dL$ 미만인 경우에 소환율, 양성예측률, 민감도, 특이도가 각각 4.8%, 3.57%, 75%, 95.3%이었다. 결 론 : 결론적으로 선천성 갑상선기능저하증에 대한 신생아 선별검사에서 갑상선자극호르몬 및 유리 $T_4$ 모두를 선별검사로 사용하는 것은 타당하고, 현재의 cut-off value가 소환율이 높기는 하나 검사의 민감도를 고려할 때 cut-off를 바꾸기에는 문제가 있을 것으로 생각되며 향후 더 큰 대상군을 바탕으로 한 재평가가 필요하리라 생각된다.

THE FRACTIONAL WEAK DISCREPANCY OF (M, 2)-FREE POSETS

  • Choi, Jeong-Ok
    • 대한수학회보
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    • 제56권1호
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    • pp.1-12
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    • 2019
  • For a finite poset $P=(X,{\preceq})$ the fractional weak discrepancy of P, denoted $wd_F(P)$, is the minimum value t for which there is a function $f:X{\rightarrow}{\mathbb{R}}$ satisfying (1) $f(x)+1{\leq}f(y)$ whenever $x{\prec}y$ and (2) ${\mid}f(x)-f(y){\mid}{\leq}t$ whenever $x{\parallel}y$. In this paper, we determine the range of the fractional weak discrepancy of (M, 2)-free posets for $M{\geq}5$, which is a problem asked in [9]. More precisely, we showed that (1) the range of the fractional weak discrepancy of (M, 2)-free interval orders is $W=\{{\frac{r}{r+1}}:r{\in}{\mathbb{N}}{\cup}\{0\}\}{\cup}\{t{\in}{\mathbb{Q}}:1{\leq}t<M-3\}$ and (2) the range of the fractional weak discrepancy of (M, 2)-free non-interval orders is $\{t{\in}{\mathbb{Q}}:1{\leq}t<M-3\}$. The result is a generalization of a well-known result for semiorders and the main result for split semiorders of [9] since the family of semiorders is the family of (4, 2)-free posets.