• Journal of Applied Biological Chemistry
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• 제42권4호
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• pp.175-179
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• 1999

Grape seed oil was extracted using different preparatory treatments as follows: (1) grinding, (2) grinding and roasting, (3) grinding and wet- roasting, (4) grinding, roasting, and wet-roasting, and (5) grinding, wet-roasting, and wet-roasting. The highest antioxidant activity was obtained from the sample with the method (2). Initial states of oxidation were similar except method (1) that showed more oxidized state, being P.O.V.8. Acid values were observed in the range from 1.42 to 1.89. The lowest acid value was found as 1.42 in method (1) and those of others were somewhat higher, indicating that heating process of roasting produced some free fatty acids. From the results of sensory evaluation, the best odor and taste were obtained from the methods (2) and (3). Repetitive procedure of wet-roasting, like method 5, caused some loss of flavor components and decrease in the sensory evaluation score. Addition of grape seed oil (method 2) to soybean and perilla oil at the level of 20% retained considerable antioxidant activities as much as 4.3 and 5 times, respectively, than 100% soybean or perilla oil stored for 12 weeks. When soybean or perilla oil was mixed with 20% grape seed oils, P.O.V. decreased to half of that of unmixed oils.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2015년도 추계학술대회
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• pp.560-563
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• 2015

기존에 사용되어지는 도어락 시스템은 키 또는 카드, 패드를 이용하는 방식으로 복제, 분실, 훼손 등의 위험과, 타인에게 노출되는 문제점을 가지고 있다. 본 논문에서는 기존의 도어락 시스템 문제점을 보완하고자 스마트폰에 내장된 Bluetooth통신과 OTP(One-Time-Password), Hide-Key 인증방식 및 Arduino를 활용한 스마트폰 기반의 무선 OTP 도어락 시스템 설계 및 구현함으로써 사용자들은 보안 및 노출의 위험성에서 벗어나 보다 편리하고 안전한 생활을 가능하게 한다.

• 한국지역사회생활과학회지
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• 제22권3호
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• pp.407-416
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• 2011

The study examined and compared relationships among self-esteem, self-efficacy, and academic achievement of children in poverty and the comparative groups. The subjects of this study were 97 elementary school students who had benefited from the free meal project and 97 students as the comparative group who did not receive the benefit. Descriptive statistics, Cronbach's ${\alpha}$ tests, and multiple regression analysis were employed to analyze the data. The results showed that academic scores of the comparative group were statistically higher than those of children in the poverty group in Korean language, mathematics, science, and sociology. Also, self-esteem of children in the poverty group was lower than that of the comparative group's in terms of leadership and popularity. The poverty group also showed lower self-efficacy in self-regulated efficacy tasks. Finally, multiple regression analysis demonstrated that different sub-factors of self-esteem and self-efficacy predicted the academic achievement of children in poverty group and the comparative groups.

• 한국식품과학회지
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• 제16권2호
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• pp.251-253
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• 1984

리파제 활성을 측정하는 간편한 방법을 개발하였다. 본 방법에 의하면 효소작용에 의해 생성된 유리지방산과 측정하는 색도와 서로 직선관계를 보였으며. 측정 범위는 long chain지방산인 경우 올레인산으로 환산하여 $0.05-1.5\;{\mu}moles$이었으며 short chain지방산인 경우 카프로인산으로 환산하여 $0.2-2.0\;{\mu}moles$의 범위였다. 본 방법의 장점은 종래의 "Copper Soap" 추출방법에서 상부 용매층 제거에 많은 시간을 소비하는 과정을 클로로포름-핵산-에타놀 혼합용매와 NaCl로 포화시킨 copper reagent를 사용하므로서 손쉽게 해결하였다.

• 한국레이저가공학회지
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• 제14권4호
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• pp.21-27
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• 2011

In this work, we have studied on time-resolved transient reflective image of single crystalline Si surface after single-shot fs-laser irradiation with varying the laser fluence under two different laser spot sizes. The temporal profiles of transient reflectivity changes as well as its maximum values at the early delay time were found to be strongly dependent on both the laser beam spot size and laser fluence. We have interpreted the dependence of transient reflectivity changes on the laser spot size in terms of a relaxation of the generated free carriers to the bulk silicon, which should be interacted with the plasma.

• Nutritional Sciences
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• 제9권4호
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• pp.330-334
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• 2006

Chemical composition of the Eucommia ulmoides bark, including extractives, proximate, mineral, fatty acid and monosaccharide compositions, was studied The most abundant mineral was calcium (533.17 mg/l00 g). $\alpha-linolenic$ acid (24.7%) and linoleic acid (24.3%), showed higher contents among the fatty acids. Major monosaccharides of E. ulmoides balk were arabinose (13.94 mg/g), xylose (18.91 mg/g) and glucose (119.7 mg/g). From the bark of E ulmoides, four compounds were isolated and their structures were elucidated as caffeic acid (I), kaempferol (II), quercetin (III) and isoquercitrin (IV) by spectroscopic analysis such as NMR and MS, including cellulose TLC and other chemical evidence such as hydrolyzation and acetylation. The antioxidant activities of four isolated compounds were evaluated by DPPH free radical scavenging, hydroxyl scavenging and reducing power assays. The results indicated that all the isolated compounds showed higher DPPH radical scavenging activity than $\alpha-tocopherol$ and BHT that were used as positive controls and these four compounds exhibited considerable reducing power and hydroxyl radical (OH) scavenging activity. Considering from the results above, it suggests that the E. ulmoides bark is a potential natural source of antioxidant material.

• Natural Product Sciences
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• 제25권2호
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• pp.122-129
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• 2019

The roots of Phlomis umbrosa (Turcz.) (Phlomidis Radix) have been traditionally used to treat cold, reduce swelling and staunch bleeding. Four iridoids (1 - 3 and 5) and six phenylethanoid derivatives (4, and 6 - 10) were isolated from the roots of P. umbrosa. A simple, sensitive, and reliable analytical HPLC/PDA method was developed, validated, and applied to determine 10 marker compounds in Phlomidis Radix. Furthermore, the isolates were evaluated for cytotoxic and anti-oxidant activities as well as DPPH-HPLC method. Among them, compounds 4 and 6 - 9 displayed potent anti-oxidant capacities using DPPH assay with $IC_{50}$ values of $27.7{\pm}2.4$, $10.2{\pm}1.1$, $18.0{\pm}0.8$, $19.1{\pm}0.3$, and $19.9{\pm}0.6{\mu}M$, and compounds 6, 8, and 9 displayed significant cytotoxic activity against HL-60 with $IC_{50}$ values of $35.4{\pm}3.1$, $18.6{\pm}2.0$, and $42.9{\pm}3.0{\mu}M$, respectively.

• 대한한의학회지
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• 제41권4호
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• pp.112-119
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• 2020

Objectives: The present study reports a case of chronic anemia patient who was significantly improved after taking Nokyongdaebo-tang (NYDBT) Methods: A 48-year-old male patient diagnosed with iron deficiency anemia (IDA) visited the Daejeon Korean medicine Hospital of Daejeon University on June 2018. The patient was treated with Korean medicine for 23 months including acupuncture, herbal medicine and Sasang constitutional medicine prescription. Improvement of anemia was assessed by changes of Hemoglobin value. Laboratory analysis was used to evaluate the safety of treatment. Results: Chronic anemia has significantly improved since taking NYDBT on 9 days (2019.12.09-2019.12.17). The Hb value has been maintained in the normal range since it first entered the normal range on January 18, 2020. The patient had become transfusion-free and this condition persisted for 6 months after stopping the transfusion. Conclusion: This case demonstrates the therapeutic potential of Sasang constitutional medicine for chronic anemia as a personalized medicine.

• BMB Reports
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• 제55권11호
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• pp.553-558
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• 2022

Hepatocellular carcinoma (HCC) is dangerous cancer that often evades early detection because it is asymptomatic and an effective detection method is lacking. For people with chronic liver inflammation who are at high risk of developing HCC, a sensitive detection method for HCC is needed. In a meta-analysis of The Cancer Genome Atlas pan-cancer methylation database, we identified a CpG island in the USP44 promoter that is methylated specifically in HCC. We developed methylation-sensitive high-resolution melting (MS-HRM) analysis to measure the methylation levels of the USP promoter in cell-free DNA isolated from patients. Our MS-HRM assay correctly identified 40% of patients with early-stage HCC, whereas the α-fetoprotein test, which is currently used to detect HCC, correctly identified only 25% of early-stage HCC patients. These results demonstrate that USP44 MS-HRM analysis is suitable for HCC surveillance.

• 한국주조공학회지
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• 제42권3호
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• pp.191-197
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• 2022

This study aims to improve the machinability of gray cast irons in high speed cutting by using nonmetallic inclusions. In this research, small quantities of AL and Mg were added to conventional gray cast irons without influencing their mechanical characteristics and castability to investigate the effects of these nonmetallic inclusions in the gray cast irons on tool wear in high speed cutting. During the high speed turning of gray cast iron containing Al and Mg using a cermet tool, protective layers consisting of Al, Mg, Si, Mn, S and O were detected on the flank face and rake face of the tool, and flank and crater wear were significantly reduced compared to the turning of conventional gray cast iron and gray cast iron added with Al. The effect of inclusions on tool wear increased with increasing cutting speed, and flank and crater wear was the smallest at the cutting speed of 700m/min. Moreover, in face milling, the addition of Al and Mg drastically decreased the wear rate, and wear hardly progressed even in prolonged cutting length after initial wear. The amount of adhesion on tool faces increased as the cutting speed increased. This increase in cutting speed resulted in the formation of a thick protective layer and the reduction of tool wear. Furthermore, the addition of small amounts of Al and Mg prevented thermal cracks in the face milling of gray cast irons.