• 대한정형외과학회지
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• 제56권6호
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• pp.498-503
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• 2021

목적: 컴퓨터 단층 촬영 영상을 이용하여 한국인에서 상완골 근위부 골절 치료에 적용되는 직선형 전향적 상완골 골수 내 금속정의 이상적 삽입점 위치를 알아보고 해부학적 적합성을 분석하고자 한다. 대상 및 방법: 2014년 5월부터 2016년 10월까지 견관절 외상으로 컴퓨터 단층 촬영을 시행한 환자 중 건측 견관절을 동시에 촬영한 한국인 74예를 대상으로 하였으며, 평균 나이는 64.5세(범위, 22-95세)였다. 영상의학적 평가는 건측 근위 상완골의 컴퓨터 단층 촬영 영상을 이용하여 다면 재구성(multiplanar reconstruction) 기법을 이용하였다. 직선형 골수정의 이상적 삽입점은 상완골 골수강 내 중심축과 상완골두가 만나는 점으로 선정하였으며 삽입점과 국소 해부학적 위치와의 거리를 측정하였다. 삽입점에서 극상건 부착부의 가장 내측까지의 관상면상 거리를 임계거리(critical distance)로 정의하고 이를 이용하여 삽입점과 회전근개 부착부와의 근접성을 평가하였다. 회전근개의 손상을 피하고 충분한 고정력을 얻기 위한 임계거리는 Euler 등이 제시한 대로 8mm 이상 확보 되어야 하며, 8 mm 미만인 경우를 위험형(critical type)으로 정의하였다. 임계거리와 성별, 나이, 키, 몸무게, 신체용적지수(body mass index)와의 통계적 유의성을 확인하였다. 결과: 이 연구에서 이상적인 삽입점의 위치는 이두구 외측연에서 시상면상 거리인 전후 거리는 평균 11.5 mm (범위, 4.0-16.6), 대결절의 가장 외측연에서 관상면상 거리인 내외 거리는 평균 20.5 mm (범위, 16.3-27.4)였다. 이상적 삽입점에서 극상건 부착부의 가장 내측까지의 관상면상 거리인 임계거리는 평균 8.0 mm (범위, 4.1-16.6)이며, 임계거리가 8 mm 미만인 위험형(critical type)ㅏ이은 74예 중 41예(55.4%)였다. 결론: 한국인에서 직선형 전향적 상완골 골수 내 금속정의 사용시, 상완 이두구의 외측연에서 후방으로 11.5 mm, 대결절 외측연에서 내측으로 20.5 mm 지점이 평균적인 이상적 삽입점의 위치였다. 하지만 55.4%의 경우에서 이상적 삽입점의 위치로 삽입할 경우 회전근개의 손상을 줄 수 있는 위험형(critical type)이였으므로, 술 전 치료방법의 선택 과정에서 환자 개개인의 해부학적 특성을 충분히 고려하여야 한다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제34권3호
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• pp.250-265
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• 2008

Distraction osteogenesis is a well-established clinical treatment for limb length discrepancy and skeletal deformities. Appropriate mechanical tension-stress is believed not to break the callus but rather to stimulate osteogenesis. In contrast to fracture healing, the mode of bone formation in distraction osteogenesis is primarily intramembranous ossification. Although the biomechanical, histological, and ultrastructural changes associated with distraction osteogenesis have been widely described, the basic biology of the process is still not well known. Moreover, the molecular mechanisms in distraction osteogenesis remain largely unclear. Recent studies have implicated the growth factor cascade is likely to play an important role in distraction. And current reserch suggested that mechanical tension-stress modulates cell shape and phenotype, and stimulates the expression of the mRNA for bone matrix proteins. The purpose of this study is to examine the pattern of expression of growth factors($TGF-{\beta}1$, IGF-I, bFGF) and extracellular matrix proteins(osteoclacin, osteonectin) related to osteogenesis by osteodistraction of the mandible in rabbits. 24 rabbits is used for this experiment. Experimental group are gradual distraction(0.7mm, twice/day), acute distraction(1.4mm, twice/day) and control group is only osteotomized. After 5 days latency, osteotomic site is distracted for each 7 days and 3.5 days. Consolidation period is 28 days. The animal is sacrificed at the 3th, 7th, 14th, 28th. The distracted bone is examined by immunohistochemical analysis and RT-PCR analysis. The results obtained from this study were as follow : No significant difference was found on clinical examination according to distraction rate, but gradual distraction was shown to improve regenerate bone formation on radiographic and histologic examination. Growth factors and extracelluar matrix proteins expression increased in distraction group than control group. From these results, it could be stated that graudal distraction is shown to improve and accelerate bone formation and mechanical stress like distraction has considerable effects on osteogenesis related factors. And rabbit is the most appropriate animal model for further reseach on the molecular mechanisms that mediate osteodistraction. It is believed that understanding the biomolecular mechanisms that mediate distraction osteogenesis may guide the development of targeted strategies designed to improve distraction osteogenesis and accelerate bone healing.

• Structural Engineering and Mechanics
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• 제63권3호
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• pp.361-370
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• 2017

Through the use of finite element analysis and acoustic emission techniques we have evaluated the interfacial failure of a carbon fiber reinforced polymer (CFRP) repair patch on a notched aluminum substrate. The repair of cracks is a very common and widely used practice in the aeronautics field to extend the life of cracked sheet metal panels. The process consists of adhesively bonding a patch that encompasses the notched site to provide additional strength, thereby increasing life and avoiding costly replacements. The mechanical strength of the bonded joint relies mainly on the bonding of the adhesive to the plate and patch stiffness. Stress concentrations at crack tips promote disbonding of the composite patch from the substrate, consequently reducing the bonded area, which makes this a critical aspect of repair effectiveness. In this paper we examine patch disbonding by calculating the influence of notch tip stress on disbond area and verify computational results with acoustic emission (AE) measurements obtained from specimens subjected to uniaxial tension. The FE results showed that disbonding first occurs between the patch and the substrate close to free edge of the patch followed by failure around the tip of the notch, both highest stress regions. Experimental results revealed that cement adhesion at the aluminum interface was the limiting factor in patch performance. The patch did not appear to strengthen the aluminum substrate when measured by stress-strain due to early stage disbonding. Analysis of the AE signals provided insight to the disbond locations and progression at the metal-adhesive interface. Crack growth from the notch in the aluminum was not observed until the stress reached a critical level, an instant before final fracture, which was unaffected by the patch due to early stage disbonding. The FE model was further utilized to study the effects of patch fiber orientation and increased adhesive strength. The model revealed that the effectiveness of patch repairs is strongly dependent upon the combined interactions of adhesive bond strength and fiber orientation.

• 농업과학연구
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• 제41권4호
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• pp.473-480
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• 2014

Upon setting up a dedicated plastic greenhouse for tomato cultivation developed by the Rural Development Administration on the Gyehwa reclaimed land, this study was aimed at analyzing the problems can be occurred in the installation of plastic greenhouse on reclaimed lands as well as finding out solutions for improvement. A relatively cheaper wooden pile was used in the installation in order to supplement the soft ground conditions. Based on the results of ground investigation of the installation site, both the allowable bearing capacity and pulling resistance of the wooden pile with a diameter of 150 mm and a length of 10 m were computed and came out to be 30.645 kN. It was determined that the values were enough to withstand the maximum compressive force (17.206 kN) and the pullout force (20.435 kN) that are generally applied to the greenhouse footing. There are three problems aroused in the process of greenhouse installation, and the corresponding countermeasures are as follow. First, due to the slightly bent shape of the wooden pile, there were phenomenon such as deviation, torsion, and fracture when driving the pile. This could be prevented by the use of the backhoe (0.2) rotating tongs, which are holding the pile, to drive the pile while pushing to the direction of the driving and fixing it until 5 m below ground and applying a soft vibrating pressure until the first 2 m. Second, there exists a concrete independent footing between the column of the greenhouse and the wooden pile driven to the underground water level. Since it is difficult to accurately drive the pile on this independent footing, the problem of footing baseplate used to fix the column being off the independent footing was occurred. In order to handle with this matter, the diameter of the independent footing was changed from 200 mm to 300 mm. Last, after films were covered in the condition that the reinforcing frame and bracing are not installed, there was a phenomenon of columns being pushed away by the strong wind to the maximum of $11m{\cdot}s^{-1}$. It is encouraged to avoid constructions in winter, and the film covering jobs always to be done after the frame construction is completely over. The height of the independent footing was measured for 9 months after the completion of the greenhouse installation, and it was found to be within the margin of error meaning that there was no subsidence. The extent to the framework distortion and the value of inclinometers as well showed not much alteration. In other words, the wooden pile was designed to have a sufficient bearing capacity.

• 대한의용생체공학회:의공학회지
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• 제30권1호
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• pp.49-55
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• 2009

Purpose : The aim of this study is to evaluate a possibility of clinical application for the effects of low intensity ultrasound stimulation (LIUS) in morphological characteristics (i.e., structure, bone mineral density) of bone on osteoporotic fracturesprevention. Materials and Methods : Eight virgin 14-week-old ICR mice (approximate weight 25g) were used and ovariectomized (OVX) to induce osteoporosis. Right tibia (US) for each mouse served as the LIUS (1.5MHz frequency, 1.0 kHz pulse repetition on frequency, $30mW/cm^2$ intensity, $200{\mu}s$ pulse length, and stimulation for 20 minutes a day and 5 days a week over a 6-week period). Left tibia (CON) for each mouse served as the non-stimulated controls. Structural parameters and bone mineral density ($g/cm^3$) on trabecular bone of tibiae were calculated and measured from images derived in-vivo micro computed tomography (micro-CT) at 0 week and after 6weeks. Results : The BV/TV and Tb.N in US group were significantly bigger than those in CON group. The Tb.Pf in US group, moreover, was significantly smaller than that in CON group (p<0.05).For the others structural parameters and BMD, however, there were no significant difference between US group and CON group (p>0.05). Conclusion : The LIUS might prevent bone loss and keep bone connectivity in osteoporotic bones. Therefore, the LIUS might prevent effectively the osteoporotic fractures in clinics.

• 한국생물공학회:학술대회논문집
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• 한국생물공학회 2001년도 추계학술발표대회
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• pp.867-870
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• 2001

아급성 독성 시험으로부터, 미립구내의 레티노익 산을 기준으로 한 투여량이 100mg/kg 일때는 4마리의 치사 개체가 보이는 등의 심각한 독성 효과가 유발되었으며, 25 및 50mg/kg인 경우에 독성 효과가 거의 나타나지 않음을 관찰하였다. 50mg/kg의 투여량의 경우, 일부 동물에서 뼈골절 현상이 나타났지만, 이러한 독성효과는 항염증제를 같이 투여함으로써 극복될 수 있을 것으로 생각되어졌다. 따라서, 앞으로의 실험에서는 항염증제를 이용하여, 가능한 독성을 억제하연서, 보다 빠른 기간 내에 상태가 회복될 수 있도록 하는 연구를 행할 것이다.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제11권1호
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• pp.50-62
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• 1989

저자는 1982년 1월부터 1987년 12월까지 대구시내 주의료기관인 5개 종합병원에 입원가료한 바 있는 하악골 골절환자 677명을 대상으로 임상적 연구를 시행한 바 다음과 같은 결과를 얻었다. 발생빈도에 있어서 연도별로는 약간의 증가추세에 있었고, 월별로는 5월과 9월에 호발하였고 지역별로는 대구시(55.7%)가 많았으며 대도시 (63.0%)에서 다소 높았다. 연령별 및 성별에서 20대(38.3%)에서 가장 호발하였으며 10대(18.5%), 30대 (18.0%)의 순으로 나타났으며 남녀비는 4.64 : 1로서 남자에게서 호발하였다. 원인별로 볼때 구타(31.5%), 교통사고 (29.5%)와 추락(15.2%), 전도(15.1%)로 많은 비중을 나타내었으며,별로 보면 20-40시 사이에 구타가 가장 많았다. 골절부위별로는 하악골 단독골절이 95.5%였으며 중안면골 골절이 동반된 경우가 4.5%였으며 골절 부위 수는 총 1,033개로서 1인당 평균 1.53개였으며 정중부(39.8%), 우각부(25.2%), 과두부(22.7%)의 순이었으며 정중부를 제외한 좌우측 비교에서 좌측이 364례로서 우측의 257례보다 많았다. 수상후 24시간이내에 전체의 62.9%가 내원하였으며, 1차 진료기관을 거친 경우가 42.4%였으며 유형별로는 일반의원(44.6%), 일반병원(27.9%) 및 치과의원(25.4%)의 순으로 나타났다. 처치내용별로는 관혈적정복수술이 전체의 55.0%를 차지하였고 37.2%는 비관혈적 정복수술을 받았으며, 소아에서는 주로 비관혈적 정복수술이 50.6%를 차지하였다.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제11권1호
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• pp.79-86
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• 1989

The is a retrospective study on the transoral approach to open reduction of the Mandibular fractures. Our study was based on a series of 64 patients with mandibular fractures among 99 patients of facial bone fractures who had been treated by transoral approach with or without extraoral approach at Department of Oral and Maxillofacial Surgery, Yonsei Medical Center, Yonsei University from January 1981 to October 1988. We studied favorite sites of open reduction, fixation methods, results and prognosis related to transoral approaches of Mandibular fractures, and which compared with extraoral approaches. The results obtained are as follows : 1. The transoral open reduction was used more frequently in Mandibular fractures(64.6%) than Midfacial bone fractures(35.4%). Among 64 patients of mandibular fractures, 47 patients(73.4%) were treated only by transoral approach and others(26.6%) were treated by both trans- and extra-oral approach. Among 92 sites of mandibular fractures, 75 sites(81.5%) were treated by transoral approach and 17(18.5%) were treated by extraoral approach. 2. The most favorite site for transoral approach compared with extraoral approach was Symphysis(100%), and Angle(62.5%) was next in order of frequency on Mandibular fractures. 3. Direct Interosseous Wiring(DIW) was most commonly used for fixation(64.6%) and Miniplate osteosynthesis was used next in 28.1%. 4. Simple(39.1%) and Compound(52.2%) fractures were frequently indicated for transoral approach, however comminuted fractures were rarely indicated. 5. The direction of fracture lines on Angle of the mandible did not influence to determine whether transoral approach should be selected or not. However this area seemed to be more difficult to reduce exactly by transoral procedure than other areas because simultaneous superior and inferior fixation was applied predominantly on this area. 6. The success rate of reduction and fixation analyzed from us was more excellent in Direct Interosseous Wiring(29/53=54.7%) than in Rigid Internal Fixation(9/29=31.0%). But it might be depended upon various factors as like as sugeon's skill. 7. The postoperative complication due to transoral open reduction of mandible was not high(12.0%) and this rate was similar with other published reports.

• 구강회복응용과학지
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• 제34권2호
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• pp.89-96
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• 2018

목적: 본 연구의 목적은 비스 아크릴 복합 레진의 수리 시 지연시간, 표면처리, 수리재료가 미치는 영향을 전단 결합강도 비교를 통해 알아보고, 폴리메틸 메타크릴레이트 레진을 이용한 비스 아크릴 복합 레진 수리의 효용성을 평가하고자 하는 것이다. 연구 재료 및 방법: 총 90개의 비스 아크릴 복합 레진 시편을 제작하였고, 지연시간, 표면처리, 수리재료에 따라 10개씩 9개의 실험군으로 분류하였다. 각각의 시편들은 제작 직후 만능시험기를 사용하여 전단 결합강도를 측정하였고, 통계분석 프로그램(IBM SPSS statistics 20)을 이용하여 분석하였다. 전단 결합강도 측정 후 시편의 파절 단면을 관찰하였다. 결과: 시편 제작 직후, 접착제(bonding agent)를 이용하여 광중합형 유동성 복합 레진을 접착한 실험군에서 가장 높은 전단 결합강도를 보였다($17.54{\pm}3.14MPa$). 결론: 비스 아크릴 복합 레진을 수리할 때 경과시간에 따라 재제작 여부를 고려해야 하며, 효과적인 수리를 위해 사용부위나 목적에 따라 알맞은 재료와 표면처리 방법을 고려하는 것이 바람직할 것이다.

• 지질공학
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• 제20권3호
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• pp.329-338
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• 2010

OO지역에 건설되는 경전철 노선은 경기편마암복합체 내 흑운모 편마암, 석영장석질편마암, 석회암 및 석회규산염암, 반상변정질편마암과 중생대에 이들을 관입한 반화강암이 분포하는 지역이다. 이 지역은 3차례 이상의 습곡작용을 받았으며, 첫 번째 변형작용(D1)은 습곡축면이 엽리면과 거의 평행한 등사습곡 내지 층간습곡이며, 두 번째 변형작용(D2)은 F1습곡이 재습곡작용을 받은, 습곡축면의 경사가 거의 수직인 폐쇄습곡이며 세 번째 변형작용(D3)은 이들 F1, F2습곡을 재습곡 시킨 개방습곡이다. 이 지역에는 서북서 방향의 곤지암단층이 지나는대, 이 단층은 단층파쇄대가 3 m정도이며 손상대는 약 10 m 이상이고 연장도 15 km로 추정하였다. 조사지역을 지나는 두개의 터널 중에서 AA터널 지역 시점 및 종점부 전체적으로 불연속면의 분포가 남쪽, 북서 및 남동쪽 방향으로 경사지는 비슷한 경향을 나타내고 있으며 AA터널의 굴진방향이 대략 남동-북서임을 고려할 때 시 종점부의 북서방향의 절리인 set3 그룹이 터널진행과 평행하기 때문에 불리한 상황이다. BB터 널은 굴진방향이 대략 시점부에서는 $100^{\circ}-280^{\circ}$ 그리고 종점부에서는 $125^{\circ}-305^{\circ}$임을 고려할 때 불연속면들이 터널굴착방향과 사교하기 때문에 터널굴착에 영향을 주지는 않음이 밝혀졌다.