• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.5 no.1
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• pp.19-44
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• 2010

This study intend to analyze effect on a change mental feature of founder received entrepreneurship short-term education called the successful foundation package. In other words, what kind of change the mental feature of founder before and after entrepreneurship education. The founder of the psychological characteristics include the locus of control, risk-taking propensity, need for achievement, ambiguity tolerance and specially new psychological trait, that is, creativity. The result of paired T-test and ANCOVA on pre-founders who received Entrepreneurship short-term education which called successful business start-up package is that need for achievement, ambiguity tolerance and creativity among pre-founders' psychological characteristics are enhanced by Entrepreneurship short-term education. However ANCOVA shows that there are no psychological characteristics changes according to age, education, the number of Entrepreneurship education.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.17
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• pp.7929-7933
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• 2015

Background: The incidence of breast cancer in India is on the rise and is rapidly becoming the number one cancer in females, pushing the cervical cancer to the second position. Most of the predisposition to hereditary breast and ovarian cancer has been attributed to inherited defects in two tumor suppressor genes BRCA1 and BRCA2. Alterations in these genes have been reported in different populations, some of which are population-specific mutations showing founder effects. Two specific mutations in the BRCA1 (185delAG) and BRCA2 (6174delT) genes have been reported to be of high prevalence in different populations. The aim of this study was to estimate the carrier frequency of 185delAG and 6174delT mutations in eastern Indian breast cancer patients. Materials and Methods: We selected 231 histologically confirmed breast cancer patients from our tertiary cancer care center in eastern India. Family history was obtained by interview or a self-reported questionnaire. The presence of the mutation was investigated by allele specific duplex/multiplex-PCR on genomic DNA extracted from peripheral blood. Results: A total of 231 patients (age range: 26-77 years), 130 with a family history and 101 without were screened. The two founder mutations 185delAG in BRCA1 and 6174delT in BRCA2 were not found in any of the subjects. This was confirmed by molecular analysis. Conclusions: Our findings suggest that these BRCA mutations may not have a strong recurrent effect on breast cancer among the eastern Indian population. The contribution of these founder mutations to breast cancer incidence is probably low and could be limited to specific subgroups. This may be particularly useful in establishing further pre-screening strategies.

• Journal of Digital Convergence
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• v.15 no.8
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• pp.59-68
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• 2017

This study is a study on the entrepreneurial characteristics of entrepreneurship by marketing competency. This study examines the relationship between the characteristics of entrepreneurs and their marketing competence, and examines the effects of these characteristics on entrepreneurial performance. The results of the empirical analysis show that the characteristics of entrepreneurs influence on entrepreneurship performance. Second, marketing competence affects entrepreneurial performance. Third, it is found that the characteristics of entrepreneurs influence the entrepreneurial performance according to marketing competence. Therefore, this study confirms that the characteristics of entrepreneurs and marketing competence affect the performance of entrepreneurship, and that the characteristics of entrepreneurs influence the entrepreneurship performance according to marketing competence. Therefore, It is significant to provide theory and implications.

• Journal of Digital Convergence
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• v.10 no.11
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• pp.103-114
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• 2012

The study is analyzed that policy support impact on youth entrepreneurship and to purpose enhancing the effectiveness of the policy support, would like to empirical study on support performance by start-up support program through education level of the founder, performance of the establishment enterprises and an empirical study of start-up support. This study reported that start-up support should be different from impact of performance of support by young founder to participate in the success of entrepreneurship incubator package or preliminary young founders and is focused on study of policy support. Examines the literature of associated young founder's characteristics and entrepreneurship support policies at domestic and foreign, and the government's support policies in order to achieve the purpose of this study, survey research as the basis of the model was set. This study surveyed to university student which were trained nationwide entrepreneurship program in order to validate the research model. The survey targeted engineering students who is practical technology foundation possible during from June 1, 2012 to June. 15, 2012, the way of data collection was directly surveryed to engineering students who participated in the entrepreneurship program. and an empirical analysis were collected each 157 call.

• Journal of Korean Society of Forest Science
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• v.72 no.1
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• pp.16-26
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• 1986

Allozyme study on a small pitch pine stand originating and expanded rather rapidly from a few founder trees indicated that the colonization of the pitch pine population was made progressively from the place where the founder trees located to another by moving in cohorts of seeds from a limited number of family or genetically closely related family groups in line with the succeeding generations. This pattern of migration and colonization resulted marked differences in allelic and genotypic frequencies at many of the allozyme loci between the initially colonized subpopulation on the south-facing slope and the lately colonized subpopulation on north-facing slope of a hill. It appeared that gene fixation due to inbreeding and genetic drift occurred at some loci in the pitch pine population or subpopulations. However, even in t 1e inbreeding small pitch pine population or subpopulations, a comparatively large amount of genetic diversity or heterozygosity was maintained due to the high levels of gene recombination at many of the gene loci and natural selections favoring for heterozygotes.

• Journal of Industrial Convergence
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• v.18 no.6
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• pp.1-7
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• 2020

In this study, we hypothesized that the needs for start-up support services may vary depending on the founder's psychological characteristics, such as self-efficacy or his attitude toward uncertainty. To verify this, a survey was conducted on the founders of 86 companies located in Business Incubators at Seoul and Daejeon and an empirical analysis was conducted based on the data. According to the analysis, the higher the self-efficacy of the founder, the more active he expressed his willingness to accept the start-up support service, which aims to provide start-up zones to busy areas outside the university. While the founder, who has experienced failure in the past, responded positively to attracting customers located outside the university. The results of this study supported the hypothesis and suggest that differentiated start-up support services should be designed by including not only characteristics at the level of start-up companies, such as industries and growth stages, but also the psychological characteristics of start-ups in important consideration.

• Journal of Digital Convergence
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• v.20 no.4
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• pp.405-410
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• 2022

As the non-face-to-face economy is activated by digital innovation, the boundaries of the industry are blurred and new start-up opportunities are occurring due to convergence between industries. Therefore, this study aims to investigate the relationship between the founders' digital competence and innovation as an antecedents that affect the substanability of start-up companies. According to the analysis results, the digital competence of the founder has a significant positive (+) effect on the innovation of the founder, and the innovation of the founder has a significant positive (+) effect on the substanability of the entrepreneur. In addition, the innovation of founders has been verified to mediate the relationship between them, and this study is meaningful in that it examines the preceding factors affecting the substanability of start-up companies.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.14 no.5
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• pp.61-78
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• 2019

This study is about the effect of the founder's self-efficacy on the sales of the founding company by focusing on the factors that are currently emphasized in the founding education. In particular, this paper starts from the consciousness of the problem that the education that is being implemented to achieve the purpose of successful start-up among various government-based start-up support projects is failing to produce many start-up failures. Entrepreneurs cannot be assessed by objective financial data, but there is a high degree of uncertainty that should be determined based on their personal and learning abilities. In addition, many previous studies, which are likely to be successful when there is a high self-efficacy in a specific field due to the influence of factors such as personal experience or learning, will answer the direction of support for start-up companies. This study focuses on the impact of the founder's self-efficacy on the sales of the founding firms, especially the sales that are the key to the survival of the founding firms. This study has six major studies. First, to analyze whether the self-efficacy of entrepreneurs with respect to entrepreneurship affects the sales of entrepreneurs. Second, to analyze whether the self-efficacy of entrepreneurs with respect to market orientation affects the sales of entrepreneurs. Analysis of whether the founder's self-efficacy affects the sales of the founding firms. Fourth, analysis of whether the founder's self-efficiency affects the sales of the founding firms' understanding of management environment changes. An analysis of whether efficacy affects the sales of a start-up company, and sixth, an analysis of whether the founder's self-efficacy of business model building ability affects the sales of a start-up company. As a result of the empirical analysis, this study found that the self-efficacy of entrepreneurs on product differentiation capability and business model building capacity had a positive influence on the sales of entrepreneurs. The self-efficacy had a positive effect on self-efficacy, and the customer orientation had a positive effect on self-efficacy on business model building capacity. Also, it was confirmed that a path exists between the components of self-efficacy and that self-efficacy through the path has a positive effect on the sales of the start-up company. Therefore, the results of this study suggest the implications of establishing such a path and strengthening self-efficacy to create the survival and start-up performance of a start-up company if the goal of the start-up company is to survive when implementing various support projects for the start-up company.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.8 no.1
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• pp.19-28
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• 2013

This study emphasize the importance of founder having knowledge on detecting entrepreneurship opportunities and analyzed how the founder detects such opportunity using what process. I used people who have found and established a company on own as a survey sample. The result is like the following. First, it's found that most founders had business motivation before the establishment and used skills and knowhow from related area of business for their business establishment that led to the comparably safe business. Second, founders were highly motivated in advance of business establishment and it is found that their chance of establishment was not from the coincidence. Third, it is also found that people had pre-education on business establishment was very on purpose and those who had not had any education had a high chance of coincidence in the establishment. Fourth, it is found that higher the desire for the business achievement, more likely that the founder's business establishment was a plan. Fifth, it is found that higher the awareness of business opportunity and vision, more likely that the founder's business establishment was on plan.

• Reproductive and Developmental Biology
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• v.31 no.3
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• pp.145-152
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• 2007

Transgenic mice were generated by microinjecting a plasmid DNA containing the SV40 (simian virus 40) large T antigen (Tag) gene fused with mouse albumin promoter/enhancer sequences into fertilized one-cell mouse embryos. Among eleven founder transgenic animals, four developed hepatocellular carcinoma, two showed kidney cancer and one developed skin and brain tumors. Three stable transgenic lines, #1-2, #1-6 and #1-11 were established. Members of the lines #1-6 and #1-11 reproducibly developed liver tumors by 8 to 10 weeks of age but did not exhibit any phenotypic changes in other tissues. Histological changes loading to liver tumor formation occurred with predictable kinetics and could be classified into three distinct stages; (a) newborn to 3 weeks of age, characterized by hyperplastic hepatocytes with reduced amounts of cytoplasm without any nuclear alterations, (b) between 4 to 8 weeks of age, characterized by diffuse liver cell dysplasia without observable tumor nodules, and (c) 9 weeks of age and thereafter, characterized by hepatocellular carcinomas in the background of extensive liver dysplasia. Metastasis to the lung from a liver carcinoma was observed in #1-11 founder animal. This transgenic mouse system displays similarities with human liver cancers in a number of aspects and provides a useful model for the study of molecular events involved in hepatocarcinogenesis.