• Journal of the Korean Geotechnical Society
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• v.25 no.11
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• pp.53-60
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• 2009

Construction of a tunnel induces rock masses damage around the tunnel. The degree of damage produced on rock masses will affect on the mechanical and hydraulic behaviors of the rock masses. In this paper, P wave velocity measured by cross-hole test was used to assess rock masses damage around the test tunnel. Initiation of source signal was carried out using mechanical impact at the source installed borehole. In consequence, the generated P wave signal was low noise and apparent wave form, which allows accurate pick-up of first arrival time. From the test, the region where rock damage is expected shows relatively low P wave velocity. In addition, with multiple points of P wave velocity measurement along each cross-hole, two dimensional P wave tomography was obtained. The tomography provides apparent view of the rock damage behind the tunnel. The measured P wave velocity was correlated with features of rock masses, porosity and Q value.

• Mycobiology
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• v.51 no.5
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• pp.360-371
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• 2023

Hispidin is an important styrylpyrone produced by Sanghuangporus sanghuang. To analyze hispidin biosynthesis in S. sanghuang, the transcriptomes of hispidin-producing and non-producing S. sanghuang were determined by Illumina sequencing. Five PKSs were identified using genome annotation. Comparative analysis with the reference transcriptome showed that two PKSs (ShPKS3 and ShPKS4) had low expression levels in four types of media. The gene expression pattern of only ShPKS1 was consistent with the yield variation of hispidin. The combined analyses of gene expression with qPCR and hispidin detection by liquid chromatography-mass spectrometry coupled with ion-trap and time-of-flight technologies (LCMS-IT-TOF) showed that ShPKS1 was involved in hispidin biosynthesis in S. sanghuang. ShPKS1 is a partially reducing PKS gene with extra AMP and ACP domains before the KS domain. The domain architecture of ShPKS1 was AMP-ACP-KS-AT-DH-KR-ACP-ACP. Phylogenetic analysis shows that ShPKS1 and other PKS genes from Hymenochaetaceae form a unique monophyletic clade closely related to the clade containing Agaricales hispidin synthase. Taken together, our data indicate that ShPKS1 is a novel PKS of S. sanghuang involved in hispidin biosynthesis.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.25 no.3
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• pp.224-228
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• 2012

We have developed new materials that lead to methyl meth acrylate monomer and styrene monomer to using polymerization method. The materials have a powder form and show liquid behavior. We call the "Electronic Bead". An our experiment, a positive-charged particle has $TiO_2$, polymer and CCA(-), while a negative-charged particle consists of carbon black, polymer and CCA(+). The charged particles have electrical characteristic of white -10 uC/g and black 10 uC/g, respectively. Also, these particles have good fluidity by additive of nano-sized silica. Using these materials, we demonstrated prototype displays that have $320{\times}320$ array of pixels and 6-in-diagonal viewable image size, driven by passive-matrix addressing. The reflectivity shows about 30% even though our experiment is at the beginning point. Also, the panel has contrast ratio 6:1. We think there are many chances to improve reflectivity through modifying components of particle resin, mixture ratio of each particle, panel structure and so on.

• Journal of Genetic Medicine
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• v.10 no.1
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• pp.1-6
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• 2013

Chronic granulomatous disease (CGD) is a rare inherited disorder of a defective NADPH oxidase enzyme, resulting in very low or no production of superoxide and subsequent reactive oxygen species. Consequently, patients with CGD are highly susceptible to severe bacterial and fungal infections. CGD is a genetically heterogeneous disease caused by defects in any one of the genes encoding the NADPH oxidase components. CGD generally affects about 3-4 per 1,000,000 individuals; thus, it is surprising that the prevalence of CGD on Jeju Island is 34.3 per 1,000,000 individuals. At present, 20 patients with CGD from 14 unrelated families on Jeju Island have been identified; nine males and 11 females. All patients with CGD tested on Jeju Island had an identical and homozygous mutation (c.7C>T in CYBA, p.Q3X in $p22^{phox}$). Therefore, all patients were autosomal recessive form of CGD. This strongly suggests that the unique and identical mutation in CYBA may be inherited from a common proband. Using mutation-specific primers to detect the mutated allele in CYBA, the frequency of subjects carrying a mutated allele was 1.3% of enrolled subjects from Seogwipo City. Further studies are necessary to elucidate how frequently this mutant allele occurs in the population on Jeju Island. Additionally, it is important to construct a national registry system to understand the pathophysiology of CGD and develop a strategy for long-term therapy.

• Fisheries and Aquatic Sciences
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• v.20 no.6
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• pp.10.1-10.7
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• 2017

Small GTPases are well known as one of the signal transduction factors of immune systems. The ADP-ribosylation factors (ARFs) can be classified into three groups based on the peptide sequence, protein molecular weight, gene structure, and phylogenetic analysis. ARF1 recruits coat proteins to the Golgi membranes when it is bound to GTP. The class I duplicated ARF gene was cloned and characterized from the olive flounder (Paralichthys olivaceus) for this study. PoARF1b contains the GTP-binding motif and the switch 1 and 2 regions. PoARF1b and PoARF1b mutants were transfected into a Hirame natural embryo cell to determine the distribution of its GDP/GTP-bound state; consequently, it was confirmed that PoARF1b associates with the Golgi body when it is in a GTP-binding form. The results of the qPCR-described PoARF1b were expressed for all of the P. olivaceus tissues. The authors plan to study the gene expression patterns of PoARF1b in terms of immunity challenges.

• Journal of Applied Biological Chemistry
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• v.53 no.4
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• pp.225-231
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• 2010

To understand the inhibitory activity with changing hydroxyl substituents ($R_l-R_9$) of polyhydroxy substituted 2-phenyl-l,4-benzopyrone analogues (1-25) against tyrosinase (PDB ID: oxy-form; 1WX2), molecular docking and the three dimensional quantitative structure-activity relationships (3D-QSARs: Comparative molecular field analysis (CoMFA) & Comparative molecular similarity indices analysis (CoMSIA)) were studied quantitatively. The statistically best models were CoMFA 1 and CoMSIA 1 model from the results. The optimized CoMSIA 1 model with the sensitivity of the perturbation and the prediction produced ($dq^2'/dr_{yy'}^2$=1.009 & $q^2$=0.51l) by a progressive scrambling analysis were not dependent on chance correlation. The inhibitory activities with optimized CoMSIA 1 model were dependent upon electrostatic factor (51.4%) of substrate molecules. Contour mapping the 3D-QSAR models to the active site of tyrosinase provides new insight into the interaction between tyrosinase as receptor and 2-phenyl-l,4-benzopyrone analogues as inhibitor. Therefore, the results will he able to apply to the optimization of a new potent tyrosinase inhibitors.

• Journal of the Korean Chemical Society
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• v.19 no.5
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• pp.339-342
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• 1975

The rates of consumption of iodine and gas evolution in hydrazine-iodine reaction in the presence of large excess of hydrazine have been studied in the pH range 0.5${\sim}$7. They are the same at very low pH and both increase to respective asymptotic values as pH is increased. The rate of iodine consumption is three orders of magnitude faster than the rate of gas evolution at higher pH. The results are explained by postulating that $N_2H_4$ but not protonated form reacts with iodine and an intermediate, probably $N_2H_2I_2$, is formed which decomposed by first order reaction of rate constant about 1.5${\times}10^{-3}sec^{-1}$ in neutral and weakly acidic solutions.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.10 no.8
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• pp.3585-3601
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• 2016

The error rate performance of circularly distributed antenna system is studied over Nakagami-m fading channels, where a dual-channel receiver is employed for the quadrature phase shift keying signals detection. To mitigate the Co-Channel Interference (CCI) caused by the adjacent cells and to save the transmit power, this work presents remote antenna unit selection transmission based on the best channel quality and the maximized path-loss, respectively. The commonly used Gaussian and Q-function approximation method in which the CCI and the noise are assumed to be Gaussian distributed fails to depict the precise system performance according to the central limit theory. To this end, this work treats the CCI as a random variable with random variance. Since the in-phase and the quadrature components of the CCI are correlated over Nakagami-m fading channels, the dependency between the in-phase and the quadrature components is also considered for the error rate analysis. For the special case of Rayleigh fading in which the dependency between the in-phase and the quadrature components can be ignored, the closed-form error rate expressions are derived. Numerical results validate the accuracy of the theoretical analysis, and a comparison among different transmission schemes is also performed.

• Transactions on Electrical and Electronic Materials
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• v.1 no.1
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• pp.32-39
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• 2000

Langmuir probe measurements of electron density, electron temperature and potential are mad in the early stage (<5${\mu}$s) of a laser ablated plasma plume, in which a positive current form positive ions and a electron current are overlapped. The plasma wes produced by focusing the second harmonic, 532 nm, of Q-switched Nd:YAG laser on a high purity carbon target. Then the laser intensity on the target of ~1.6${\times}$10$\^$15/ W/$\textrm{cm}^2$. The measured electron desities and temperatures are ~2${\times}$10/sip 11/ cm$\^$-3/ and -3 eV. In particluar , the phenomenon that the electron temperature decreased and then increased was observed,. It could be well explained that this phenomenon occurred in the process of inverse Bremsstrahlung of free electrons in plasma. Additionally, the plasma potential(>11V) was higher than the published values.

• Computers and Concrete
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• v.33 no.1
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• pp.13-25
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• 2024

In this study, contact analysis in a functionally graded (FG) layer loaded with two circular punches is solved using the finite element method (FEM). The problem is consisted of a functionally graded layer that resting on an elastic semi-infinite plane and is loaded with two rigid punches of circular geometry. External loads P and Q are transferred to the layer via two rigid punches. The finite element model of the functionally graded layer is created using the ANSYS package program and a 2-dimensional analysis of the problem is analyzed. The contact lengths, obtained as a result of the analysis are compared with the analytical solution in the literature. In the study, the effects of parameters such as distances between punches, loads, inhomogenity parameter on contact zones, initial separation loads and distances, normal stresses, stresses across depth and contact stresses are investigated. As a result, in this study, it can be said that the magnitude of the stresses occurring in the FG layer is less than the homogeneous layer, therefore the life of FG materials will be longer than the homogeneous layer. When the distance between the punches is 2.25, the initial separation distance is 6.98, and when the distance between the punches is 4, the initial separation distance decreases to 6.10. In addition, when the load increased in the second punch, the initial separation load decreased from 55 to 18. The obtained results are presented in the form of graphs and tables.