• International Journal of Naval Architecture and Ocean Engineering
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• v.10 no.4
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• pp.508-519
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• 2018

In order to design the hull form of an underwater vehicle in the conceptual design phase, the dynamic characteristics depending on the hull form parameters should be identified. Course-keeping stability, turning ability, yaw-checking ability, and mission competence are set to be the indices of the dynamic characteristics, and the geometric parameters for the bare hull and rudder are set to be the hull form design parameters. The total sensitivity of the dynamic characteristics with respect to the hull form parameters is calculated by the chain rule of the partial sensitivity of the dynamic characteristics with respect to the hydrodynamic coefficients, and the partial sensitivity of the hydrodynamic coefficients with respect to the hull form parameters. Based on the sensitivity analysis, important hull form parameters are selected, and those optimal values to satisfy the required intercept time of mission competence of a specific underwater vehicle and turning rate are estimated.

• Journal of the Society of Naval Architects of Korea
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• v.45 no.6
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• pp.601-610
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• 2008

This paper deals with a new geometrical surface modeling method of forebody's hull form which is fully defined by form parameters. The complex hull form in the forebody can be modeled by the combination of three parts: bare hull, bulbous bow and blending part which connects a bare hull and a bulbous bow. All these subdomain parts are characterized by each own form parameters and constructed with simple surface model. For this, we need only 2-dimensional hull form data and then the form parameters are calculated automatically from these data. Finally, the smooth hull form surfaces are generated by parametric design and fair-skinning. In the practical point of view, we show that this new method can be useful and efficient modeling tool by applying to the hull form surface modeling of Panamax container's forebody.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.44 no.1
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• pp.68-74
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• 2008

This study is concerned with the development of the basic planing hull form of small fishing boat in 25 knots high speed. A series of model test to determine the optimum performance hull form of actual fishing boat with 10 gross tonnage was carried out for 5 models made available planing hull form in the circulation water channel. Model test was performed with the resistance test to study the hydrodynamic characteristics of model ships and the sinkage and trim measurement to investigate the stability of model ships and also the wave pattern observation to analyze the effectiveness of model ships. As the result, the planing hull form of P-4 with deep V type bow can be derived as the best hull form with good performance especially in ship's resistance efficiency showing less residual resistance and sinkage and trim and the spray effect, etc..

• Journal of Pharmaceutical Investigation
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• v.39 no.3
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• pp.173-176
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• 2009

A new crystal form of valsartan dipotassium was isolated by recrystallization using the one-pot method. The new crystal form was identified as a monohydrate form ($C_{24}H_{27}N_5O_3K_2.H_2O$) and characterized by diffential scanning calorimetry (DSC), thermogravimetric analysis (TGA) and X-ray powder diffractometry (PXRD). The new crystal data demonstrated to be clearly different from those known for the tetrahydrate form ($C_{24}H_{27}N_5O_3K_2.4H_2O$). It was observed that the monohydrate of vasartan dipotassium salt was completely dissolved in water within 1 hour and its dissolution rate was much faster than anhydrous free form of valsartan.

• Journal of the Society of Naval Architects of Korea
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• v.46 no.6
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• pp.562-568
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• 2009

Hull form generation and variation methods to be mainly discussed in this study are based on the fairness optimized B-Spline form parameter curves (FOBFC). These curves can be used both as indirect modification function for variation and as geometric entities for hull form generation. The flexibility and functionality of geometric control technique play the most important role for the success of hull form optimization. This study shows the hydrodynamic optimization process and the characteristics of optimum design hull forms of a 14,000TEU containership and 60K LPG carrier. SHIPFLOW has been used as a CFD solver and FS-Framework as a geometric modeler and optimizer.

• International Journal of Naval Architecture and Ocean Engineering
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• v.13 no.1
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• pp.147-162
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• 2021

The problem of predicting a ship's form factor and associated scale effects has been subject to many investigations in recent years. In this study, an attempt is made to investigate whether the form factor is influenced by a change in the ship's speed by numerically modelling a geosim series of the KCS hull form by means of a RANS solver. The turbulence dependence of the problem is also studied by altering the closure model among three widely used approaches (the k-𝜔, k-𝜔 SST, and k-𝜀 models). The results show that at very low speeds (Froude numbers in the range of 0.02-0.06) the numerical model predicts changes in the form factor of a ship between 10% and 20%, depending on the turbulence model and scale factor choices. As the speed is increased further, the form factor exhibits little change, usually in the range of 1% or less. Simulations where the Reynolds number is changed by approximately two orders of magnitude, achieved by altering the value of viscosity, confirmed that the form factor can be considered Froude-dependent only for low speeds, predicting essentially identical values when high speed cases are considered.

• Honam Mathematical Journal
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• v.35 no.2
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• pp.147-161
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• 2013

In this paper we determine certain class of $n$-dimensional QR-submanifolds of maximal QR-dimension isometrically immersed in a quaternionic space form, that is, a quaternionic K$\ddot{a}$hler manifold of constant Q-sectional curvature under the conditions (3.1) concerning with the second fundamental form and the induced almost contact 3-structure.

• Journal of Pharmaceutical Investigation
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• v.33 no.2
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• pp.99-103
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• 2003

Four different crystal forms of prednisolone, two polymorphic forms and two pseudopolymorphic forms, were obtained by the recrystallization from different organic solvents under varying conditions. The isolated crystal forms were characterized by differential scanning calorimetry (DSC), thermogravimetric analysis (TGA) and X-ray powder diffraction (XRD). Form 1 was the most stable form that had the highest melting point and melt at $250.1^{\circ}C$. Form 2 was a monohydrate and Form 3 was a methanol solvate. The endothermic peak of Form 4 was shown at $230.2^{\circ}C$. When stored at different relative humidity over the period of 3 months, all of the modifications did not undergo transformation. The dissolution patterns of these four modifications were also checked in distilled water at $37{\pm}0.5^{\circ}C$, for 120 minutes. The dissolution rate of Form 4 was highest and those of Form 3, Form 2, Form 1 followed. Form 2, Form 3 and Form 4 had higher dissolution rate than Form 1.

• Journal of the Korean Chemical Society
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• v.62 no.5
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• pp.352-357
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• 2018

Celecoxib (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide) is a cyclooxygenase-2 inhibitor used in the treatment of arthritis, acute pain, and dysmenorrhoea. Celecoxib is a Biopharmaceutics Classification System (BCS) class II compound whose oral bioavailability is highly limited owing to its poor aqueous solubility. Several polymorphs of celecoxib have been identified as Form I, Form II, and Form III with melting points of about $162.8^{\circ}C$, $161.5^{\circ}C$, and $160.8^{\circ}C$, respectively. Form IV was generated from the precipitated suspension in the presence of HPMC (Hydroxypropyl methylcellulose) and Polysorbate 80. A rapid rate of dissolution is useful because the rate of dissolution of a drug typically increases its bioavailability. The aim of this study was to investigate the possibility of production of new crystal form of celecoxib that has higher solubility than Form III. New crystal form of celecoxib (Form A) has been isolated by recrystallization and characterized by differential scanning calorimetry (DSC), thermogravimetric (TG) analysis and powder X-ray diffractometry (PXRD). Form A was dissolved faster than Form III. At 30 minutes, the dissolution of Form A was 97.3%, whereas the dissolution of Form III was 82.2% (p < 0.1). After storage of three months at $20^{\circ}C$, in 24% RH (Relative Humidity), the crystal form was not transformed.

• Architectural research
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• v.16 no.4
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• pp.157-166
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• 2014

This research investigates the design process of free-form architecture to understand the design strategy and changing factors during the development phase and the cause for them. It is aimed to foresee the changing factors from the design process and to reduce design changes. It analyzes the design changes of free-form architecture based on projects with finalized documentation or under construction in South Korea. Many free-form shapes of the free-form architectures have to be adjusted to rigid-form in order to satisfy function and be economical to build. The research finds three patterns in design changes. First, from the factors for design changes: function, constructability, design, program add/subtract, efficiency, circulation; Function and Constructability are the higher factors compared with the rest. The two are the design changes suitable for actual usage and cost savings. Second, each project has different predominant factors for design changes as the degree of free-form is different. Contrary to initial expectation, the greater the degrees of free-form of the competition scheme, the higher the rate of Function among the factors for design changes. Constructability is higher when the degree of the free-form is less than others. It means that the lower the degree of the free-form, the more properly planned the space of the building is. Last, Constructability of free-form architecture is considered during the earlier design phase than definite-form, one by which the design changes by comparing 'Before fixed Space Program' (BSP) and 'After fixed Space Program' (ASP) design changes. The research would be helpful as a reference for setting up competition guidelines to reduce trial and error during the design process.