• 한국정보전자통신기술학회논문지
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• 제6권3호
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• pp.135-140
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• 2013

본 논문은 스마트 그리드의 핵심 설비중 하나인 반도체 지능형 변압기의 시스템 구성과 이에 필요한 PWM 컨버터의 PWM 생성 방식에 관한 논문으로, 반도체 지능형 변압기의 경우 입력단이 수전계통에 직접 접속되기 때문에 고전압을 견딜 수 있는 방식으로 구성되어야 하고 이를 위해서는 다단 연결방식의 PWM 컨버터의 구성이 필수적이다. 종래의 PWM 생성 방식의 경우 지령전압의 크기에 따라서 각 단별 스위칭 부하가 균등하게 분포되지 않기 때문에 이를 해결하기 위한 복잡한 리던던시를 스위칭 패턴에 추가해야 했으나, 본 논문에서 제안하는 방식의 경우 부하의 분담이 자동적으로 이루어지기 때문에 그러한 부담없이 시스템을 구성하는 것이 가능하다.

• 대한전기학회논문지
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• 제39권6호
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• pp.568-576
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• 1990

Recently, streaming electrification in forced oil cooled power transformer has been taken up as a serious problem. In this paper, the charging tendency of various insulation oils, such as mineral oil, polybutene and silicone oil has been measured by means of an injection type charging tendency measuring apparatus under various condition. The experimental data of the dependence of the leakage current on flow velocity and temperature of oil can be explained by considering the flow state such as laminar and turbulent flow. The effect of additives on the charging tendency of mineral oil has been investigated. BTA is regarded as the most effective retardant to electrification of oil among the additives chose for this investigation.

• Journal of Mechanical Science and Technology
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• 제14권12호
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• pp.1376-1385
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• 2000

This study investigates spray characteristics before and after wall impingingment of gasoline spray in suction air flow. For this study, a rectangular model intake port was made of acrylic glass, and suction air was generated by using the forced air blower contrariwise. The injector for this study was a pintle-type port gasoline injector in which an air-assist adaptor is installed to supply assisted air. A PDPA system was employed to simultaneously measure the size and velocity of droplets near the wall. Measured droplets are divided into "pre-impinging droplets"with positive normal velocity and "post-impinging droplets"were negative normal velocity for the suction flow. The velocities, size distributions and Sauter mean diameter(SMD) of pre-and post-impinging droplets for varions injection angles and air-assists are comparatively analyzed.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2013년도 춘계학술대회 논문집
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• pp.256-260
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• 2013

The fan-shroud plays the important role in cooling down the engine heat by the forced convection. As the fan-shroud is made by injection molding, the unbalance of the fan blades is inevitable, and its low frequency characteristics makes it easy to excite the resonances of the environmental structures. So controlling its vibration, specially the dominant vibration source of unbalance vibration, is one of key factor to improve the sound and vibration quality of the modern vehicles. This paper introduces the plane balancing method, the most appropriate way of controlling the fan-shroud by generating the acceleration orbit measured from 2 accelerometers, and proves its balancing effect by the experiment.

• 대한기계학회논문집
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• 제16권9호
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• pp.1780-1787
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• 1992

본 연구에서는 대수층을 시뮬레이션한 실험장치를 통하여 온도분포를 관찰하 고 자연대류에 관한 단순화된 이론적 모델을 개발하여 실험치와 비교 검토하고자 한 다.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2004년도 춘계학술대회
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• pp.2082-2087
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• 2004

In this study, the variation of spark plug location in the combustion chamber was investigated for the sake of emission characteristics from SI engine by using PDA valve. The swirl is ong of the important parameters that effects emission characteristics. PDA valve has been used to satisfy the requirements of sufficient swirl generation to improve combustion and emission reduction to effect on flow profile on a combustion chamber. Especially, the variation of spark plug location have an important effect to analyze exhaust gas and the early flame propagative process. Therefore, this test is forced that injection timing, spark timing and intake air motion govern the stable combustion. From the results, it showed that the variable spark plug location and PDA valve can be reduced exhaust gas.

• 한국임상수의학회지
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• 제19권3호
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• pp.328-332
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• 2002

Cordyceps is reputed for its broad biological activities and as a tonic for replenishing vital function in Chinese traditional medicines. As an attempt to obtain fundamental data for the development of new type Cordyceps, the effects of the fruiting bodies of cultivated fungus of Paecilomyces japonica grown on silkworm larvae on fatigue and hematotoxicity were investigated. The antifatigue activity of dongchongxiacao (Paecilomyces japonica) was studied in mice using weight loaded forced swimming performance method. The water extract of dongchongxiacao(25 mg/kg of body weight, intraperitoneal injection at 12 and 36 hours before irradiation and 30 minute and 24 hours after irradiation) showed a significant antifatigue effect in normal mice and radiation-induced fatigue mice (p<0.0005). In the experiment on the improvement of hematotoxicity, a significant difference from the irradiated controls was seen at day 3 of the group treated with dongchongxiacao and substantial differences from the irradiated controls at day 7 was also detected.

• Journal of Ginseng Research
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• 제44권4호
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• pp.644-654
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• 2020

Background: Posttraumatic stress disorder (PTSD), a mental disorder induced by traumatic stress and often accompanied by depression and/or anxiety, may involve an imbalance in the neurotransmitters associated with the fear response. Korean Red Ginseng (KRG) has long been used as a traditional medicine and is known to be involved in a variety of pharmacological activities. We used the open field test and forced swimming test to examine the effects of KRG on the depression-like response of rats after exposure to single prolonged stress (SPS), leading to activation of the serotonergic system. Methods: Male rats received KRG (30, 50, and 100 mg/kg, intraperitoneal injection) once daily for 14 days after exposure to SPS. Results: Daily KRG administration significantly improved depression-like behaviors in the forced swimming test, increased the number of lines crossed and time spent in the central zone in the open field test, and decreased freezing behavior in contextual and cued fear conditioning. KRG treatment attenuated SPS-induced decreases in serotonin (5-HT) tissue concentrations in the hippocampus and medial prefrontal cortex. The increased 5-HT concentration during KRG treatment may be partially attributable to the 5-hydroxyindoleacetic acid/5-HT ratio in the hippocampus of rats with PTSD. These effects may be caused by the activation of hippocampal genes encoding tryptophan hydroxylase-1 and 2 mRNA levels. Conclusion: Our findings suggest that KRG has an antidepressant effect in rats subjected to SPS and may represent an effective use of traditional medicine for the treatment of PTSD.

• 생물정신의학
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• 제27권1호
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• pp.27-35
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• 2020

Objectives Ketamine has been reported to have antidepressant effects or psychotomimetic effects. The aim of this study was to investigate the behavioral effects of ketamine treatment at various sub-anesthetic doses in adolescent and adult naïve mice. Methods In each experiment for adolescent and adult mice, a total of 60 male Institute of Cancer Research mice were randomly divided into 6 groups, which were intraperitoneally treated with physiological saline, 10, 20, 30, 40, and 50 mg/kg ketamine for consecutive 3 days. At 1 day after last injection, the locomotor and depressive-like behaviors were evaluated in mice, using open field test (OFT) and forced swim test (FST), respectively. Results In case of adolescent mice, ketamine dose was negatively correlated with total distance traveled in the OFT (Spearman's rho = -0.27, p = 0.039). In case of adult mice, we found significant positive correlation between ketamine dose and duration of immobility in the FST (Spearman's rho = 0.45, p < 0.001). Immobility time in the 50 mg/kg ketamine-treated mice was significantly higher compared to the saline-treated mice (Dunnett's post-hoc test, p = 0.012). Conclusions We found that the repeated treatment with ketamine could decrease the locomotor or prolong the duration of immobility in mice as the dose of ketamine increased. Our findings suggest that sub-anesthetic doses of ketamine might induce schizophrenia-like negative symptoms but not antidepressant effects in naïve laboratory animals.

• Tuberculosis and Respiratory Diseases
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• 제67권6호
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• pp.569-573
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• 2009

Idiopathic pulmonary alveolar proteinosis (PAP) is a rare disorder characterized by surfactant component accumulation in the alveolar space. Idiopathic PAP has recently been recognized as a autoimmune disease of impaired alveolar macrophage function caused by autoantibodies against granulocyte-macrophage colony-stimulating factor (GM-CSF). While whole lung lavage has been the standard treatment, not every patient shows a complete response. Subcutaneous injection or inhalation of GM-CSF is another promising treatment option for PAP. A 45-year-old patient visited our hospital for dyspnea, he was diagnosed as PAP and underwent whole lung lavage. Eighteen months later, the patient had not achieved complete remission in despite of initial response. After then he was administered with GM-CSF (5 ${mu}g/kg/day$, subcutaneous injection) for fivetimes a week during 2 months. Nine months later, the abnormal shadows in high-resolution computed tomography (HRCT) decreased and the patient fully recovered in forced vital capacity. After 60 months, the HRCT scan showed complete remission of PAP.