• Journal of the Korean Applied Science and Technology
• /
• v.32 no.4
• /
• pp.694-701
• /
• 2015

In order to get stabilized pure retinol in skin care cosmetics, developing the three layered matrix bead capsules were studied. This study relates to make a cosmetic composition using the three layered matrix capsule that could increase the stability of the active ingredient. A primary encapsulation, vitamin A (pure retinol) of active ingredient was perfectly capsulated into water-in-oil (Water-in-Oil: W/O) emulsion vesicle using PEG-10 dimethicone copolyol emulsifier. A secondary encapsulation of multiple emulsion of the water-in-oil-in-water (W/O/W) emulsion blending W/O emulsion using sucrose distearate of surfactant was developed using homogenizing emulsifying system. Pure retinol of active ingredient was stably capsulized to inside the W/O/W-multiple emulsion in order to load the triple matrix capsulation. By coating it with a polymer matrix base, encapsulated in the triple layered type, which were developed bead encapsulation of 2~10mm uniformly size. To show beautifully appearance capsulated bead type, these finish particles in this triple matrix layer were developed as a gold, green, dark brown, silver and blue color were encapsulated in the bead types. Structural particle certification of triple matrix layer was observed through SEM analysis. Stability of pure retinol was remained stable more than 99.7% for 30 days at $42^{\circ}C$ incubating conditions compared with non-capsule. This technology was applied in different formulations such as various sizes and colors that by applying the skin care cosmetics. In the future, this technology to encapsulate an unstable active ingredient, we expect to be expanded this application in the food and drug as a time delivery system.

• Journal of Biosystems Engineering
• /
• v.42 no.4
• /
• pp.301-313
• /
• 2017

Purpose: This study was conducted to discriminate between normal hulled barley and Fusarium (Fusarium asiaticum and Fusarium graminearum) infected hulled barley by using the near-infrared spectroscopy (NIRS) technique. Methods: Fusarium asiaticum and Fusarium graminearum were artificially inoculated in hulled barley and the reflectance spectrum of the barley spike was obtained by using a near-infrared spectral sensor with wavelength band in the range 1,175-2,170 nm. After obtaining the spectrum of the specimen, the hulled barley was cultivated in a greenhouse and visually inspected for infections. Results: From a partial least squares discriminant analysis (PLS-DA) prediction model developed from the raw spectrum data of the hulled barley, the discrimination accuracy for the normal and infected hulled barley was 99.82% (563/564) and 100% (672/672), respectively. Conclusions: NIRS is effective as a quick and nondestructive method to detect whether hulled barley has been infected with Fusarium. Further, it expected that NIRS will be able to detect Fusarium infections in other grains as well.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.10 no.11
• /
• pp.3384-3389
• /
• 2009

There are two major problems with current National GAP system. One was false in traceability record because it was written or inputted by farmers or distributers and no other measures to check the accuracy was valid. The other was incapability of tracking back and recalling the contaminated agricultural products. For solving these matters, IT convergence model which combined information technology with agricultural experience is elaborated. In IT convergence model, video analytic system classifies every activity depending on the pre-programmed farming process and create the traceability data automatically. Also real time trace system based on USN would solve the problem of tracking back. This system transmits the present location and monitors data of agricultural products from farm to table at all times.

• Journal of Veterinary Clinics
• /
• v.35 no.1
• /
• pp.1-6
• /
• 2018

This study reviewed the regulatory safety management system for prevention of side effects of veterinary medical devices in Korea based on data obtained through analyses of those medical devices. In order to ensure the safety of medical devices, Ministry of Food and Drug Safety has established the management system include licensing, test inspection (134 designated clinical trial agencies) and post management. In addition, it was introduce the good manufacture practice (GMP) certification system and device tracking requirements. In contrast, it is necessary to establish regulations for side effects report and awareness on veterinary medical devices in Korea. The center for veterinary medicine of FDA in the United States has been operated side effects reporting system of veterinary medical devices from user, manufactures and distributor. Due to increase the use of various kinds of veterinary medical devices for animals, it should be required to improve regulation related to the licensing procedures, GMP system, and the side effects reporting system in our country.

• Journal of The Korean Society of Agricultural Engineers
• /
• v.61 no.3
• /
• pp.89-99
• /
• 2019

The project to utilize kenaf as thermal power plant fuel has a positive effect on the unused energy utilization, greenhouse gas reduction, and farm income. However, it is analyzed that it is difficult to secure economical efficiency because the fuel cost of kenaf is higher than that of power by thermal power plant and Renewable Energy Certification (REC). The project of power generation using kenaf is meet the government's major policies, while government support is essential for securing economical efficiency. As a result of the sensitivity analysis on the ratio of the government subsidies, to secure economical efficiency, the power generation prices using kenaf through the direct financial support of the government indicate that 47% and 76% of kenaf fuel cost are supported by government in case of the Saemangeum reclamation and Gangneung-si, respectively. In the case of the government indirect policy support, if kenaf is included as a renewable energy source of Renewable Energy Portfolio Standard and REC is granted, the economic efficiency of Saemangeum reclamation and Gangneung-si is obtained when REC secured at 1.05 or more and 2.43 or more, respectively. The results of this study are meaningful in that the direct and indirect effects of the government on the development of the herbaceous energy crop, kenaf, were evaluated economically. These results are to suggest the need for demonstration study, but economics analyze and evaluate are necessary based on operational data through the demonstration phase in the future.

• Journal of Pharmacopuncture
• /
• v.24 no.2
• /
• pp.59-67
• /
• 2021

Objectives: We aimed to compare the external herbal dispensary (EHD) evaluation criteria for pharmacopuncture and the Korea Good Manufacturing Practice (KGMP) sterile medicine standards to contribute to the establishment of quality control criteria for pharmacopuncture. Methods: We obtained the KGMP standards from the Ministry of Food and Drug Safety and the pharmacopuncture certification criteria from the Ministry of Health and Welfare of South Korea. The EHD evaluation items were classified into three categories: facilities, quality control, and validation. The evaluation items were compared with the KGMP sterile medicine criteria to determine their conformance with each other, followed by a discussion among the committee of six experts and their consensus to suggest the items to complement the EHD evaluation criteria. Results: Among the KGMP sterile medicine criteria, 44 were related to the management of the facilities, and 32 pharmacopuncture evaluation items corresponded to these KGMP items (66.7%). Fifty-eight KGMP criteria were related to quality management, and 42 pharmacopuncture evaluation items corresponded to these KGMP items (72.4%). Twentyfive KGMP sterile medicine criteria were related to validation, and 11 pharmacopuncture evaluation items corresponded to these KGMP items (44.0%). Sixteen items under the pharmacopuncture EHD criteria corresponded to the KGMP sterile medicine criteria based on the consent of the experts. Among these, 4 were related to facility management, 6 were related to quality control, and 6 were related to validation. Conclusion: For the safety and quality control of pharmacopuncture, there is a need to select the criteria for the mandatory items among the proposed pharmacopuncture-EHD criteria laws and systems to ensure that the pharmacopuncture materials are produced under the pharmacopuncture-EHD in compliance with the relevant requirements. More studies are needed to secure the safety level of pharmacopuncture materials corresponding to that of conventional medicine.

• Journal of Microbiology and Biotechnology
• /
• v.32 no.4
• /
• pp.437-446
• /
• 2022

In this study, to obtain icaritin with high pharmacological activities from icariin, which has a content ratio of over 58% in the total flavonoids of Epimedium herb, a special Epimedium flavonoid-glycosidase was produced, purified and characterized from Aspergillus sp.y848 strain. The optimal enzyme production was gained in a medium containing 5% (w/v) wheat bran extract and 0.7% (w/v) Epimedium leaf powder as the enzyme inducer, and strain culture at 30℃ for 6-7 days. The molecular weight of the enzyme was approximately 73.2 kDa; the optimal pH and temperature were 5.0 and 40℃. The enzyme Km and Vmax values for icariin were 15.63 mM and 55.56 mM/h. Moreover, the enzyme hydrolyzed the 7-O-glucosides of icariin into icariside II, and finally hydrolyzed 3-Orhamnoside of icariside II into icaritin. The enzyme also hydrolyzed 7-O-glucosides of epimedin B to sagittatoside B, and then further hydrolyzed terminal 3-O-xyloside of sagittatoside B to icarisiede II, before finally hydrolyzing 3-O-rhamnoside of icarisiede II into icaritin. The enzyme only hydrolyzed 7-O-glucoside of epimedin A or epimedin C into sagittatoside A or sagittatoside C. It is possible to prepare icaritin from the high-content icariin in Epimedium herb using this enzyme. When 2.5% icariin was reacted at 40℃ for 18-20 h by the low-cost crude enzyme, 5.04 g icaritin with 98% purity was obtained from 10 g icariin. Also, the icaritin molar yield was 92.5%. Our results showed icaritin was successfully produced via cost-effective and relatively simple methods from icariin by crude enzyme. Our results should be very useful for the development of medicines from Epimedium herb.

• Mycobiology
• /
• v.51 no.4
• /
• pp.195-209
• /
• 2023

The seed borne disease such as bakanae is difficult to control. Crop yield loss caused by bakanae depending on the regions and varieties grown, ranging from 3.0% to 95.4%. Bakanae is an important disease of rice worldwide and the pathogen was identified as Fusarium fujikuroi Nirenberg (teleomorph: Gibberella fujikuroi Sawada). Currently, four Fusaria (F. fujikuroi, F. proliferatum, F. verticillioides and F. andiyazi) belonging to F. fujikuroi species complex are generally known as the pathogens of bakanae. The infection occurs through both seed and soil-borne transmission. When infection occurs during the heading stage, rice seeds become contaminated. Molecular detection of pathogens of bakanae is important because identification based on morphological and biological characters could lead to incorrect species designation and time-consuming. Seed disinfection has been studied for a long time in Korea for the management of the bakanae disease of rice. As seed disinfectants have been studied to control bakanae, resistance studies to chemicals have been also conducted. Presently biological control and resistant varieties are not widely used. The detection of this pathogen is critical for seed certification and for preventing field infections. In South Korea, bakanae is designated as a regulated pathogen. To provide highly qualified rice seeds to farms, Korea Seed & Variety Service (KSVS) has been producing and distributing certified rice seeds for producing healthy rice in fields. Therefore, the objective of the study is to summarize the recent progress in molecular identification, fungicide resistance, and the management strategy of bakanae.

• Journal of Korean Society for Quality Management
• /
• v.52 no.2
• /
• pp.201-220
• /
• 2024

Purpose: Smart farming is related to the low carbon certification system as it provides many opportunities to cultivate and manage crops in an eco-friendly, thereby reducing carbon footprint. However, there is a significant lack of consumer perception research on low carbon labels for smart farms vegetables. Therefore, this study aims to investigate consumer perceptions of smart farm vegetable and low carbon labels. Methods: This study manipulated cultivation type(general vs. smart farm) and low carbon labels (yes vs. no) as experimental stimuli. Measurement questions and the research model were validated through confirmatory factor analysis and reliability analysis. Hypotheses testing were conducted using SPSS 29.0, AMOS 28.0. Results: The results of the study showed no significant difference in consumers perceived naturalness based on cultivation types, and there was also no moderating effect of the low carbon label. There was no difference between environmental benefits and health benefits according to the cultivation type. Perceived naturalness had a significant effect on both environmental and health benefits, and environmental benefits showed a higher impact relationship. These benefits positively affected attitudes and willingness to pay a premium, Environmental benefits had a higher impact on attitudes, while health benefits had a higher impact on willingness to pay a premium. Lastly, attitudes were found to have a significant impact on the willingness to pay a premium. Conclusion: This study is valuable in that it investigated consumer perceptions of smart farms and low carbon labels that have not been previously studied. It compares the environmental and health benefits, confirming their influence on attitudes and willingness to pay a premium. The results suggest a potential expansion in academic research on smart farming and low carbon labels, offering practical insights for marketing strategies and policies for relevant companies.

• Journal of Food Hygiene and Safety
• /
• v.34 no.6
• /
• pp.551-556
• /
• 2019

Recently, due to the fact that the mineral content in the wash water of the GAP-certified melon exceeds the GAP wash water standards, there are cases where the certification cannot be maintained. Therefore, agricultural industry demand requesting relaxation of the inorganic elements standard for water quality has been increasing, taking into account the consumption characteristics of Korean melon, which is eaten after removing the peel. This study was conducted to evaluate the human risks of four inorganic materials (fluorine, arsenic, iron and manganese) based on the water quality data of 142 samples of groundwater that was used for washing GAP-certified Korean melon in Seongju area from 2017 to 2019. As a result, the HQ of four minerals in Koreans who consumed groundwater used for washing GAP-certified Korean melons in the Seongju area was below 0.10 on average. In particular, in the case of iron and manganese which are esthetic influence substances, the average HQ was 0.00. The overexposure group showed 0.01, which was lower than the HQ (average 0.01, overexposure group 0.03) of the group that consumed Korean melon. Based on all the results, even if the groundwater of the Seongju area is used to wash GAP-certified Korean melon, the impact from these four inorganic materials, including iron and manganese, for Korean population consuming Korean melon will be minimal.