• 제목/요약/키워드: Flux composition

검색결과 235건 처리시간 0.03초

아스코르빈산 팔미테이트를 함유한 리포겔의 피부 투과 및 잔류 특성 (Skin Penetration and Localization Characteristics of Lipogel Containing Ascorbyl Palmitate)

  • 이상길;우혜승;이연아;권용남;최영욱
    • Journal of Pharmaceutical Investigation
    • /
    • 제31권4호
    • /
    • pp.225-232
    • /
    • 2001
  • The present study was carried out to observe the effect of liposome dispersed gel formulation (Lipogel) on topical delivery of ascorbyl palmitate (AsP). Neutral and negatively charged MLV liposomes containing AsP were prepared with dimyristoylphosphadtidylcholine (DMPC) and dicetyl phosphate (DCP), and dispersed to poloxamer gel matrix. In the hydrolysis study in rat's skin homogenates, AsP hydrolyzed to ascorbic acid (AsA) according to the first-order kinetics with the rate constant of $2.46{\times}10^{-2}\;min^{-1}$. In the passive skin penetration study using Franz diffusion cell, lipogel systems exhibited the greater values in the flux $(J_s)$ and the amount penetrated $(Q_p)$ compared to control hydrogels containing diethyleneglycol monoethyl ether $(Transcutol^{\circledR})$ as a solubilizing agent and a penetration enhancer for AsP. The total amount penetrated $(Q_{Total})$, which is expressed as a summation of $Q_P\;and\;Q_L$, for lipogel system was about 1.4 times higher in average than that of control hydrogel. However the amount localized in the skin $(Q_L)$ was similar in both formulations. As a result, lipogel system enhanced the skin penetration of AsP, possibly due to the increase in local concentration of AsP by preferential adsorption of liposome to the skin and the enhancing effect of phospholipid in liposome composition. Moreover it was expected that the penetrated AsP would generate AsA during skin penetration by the skin esterase. In conclusion, lipogel formulation was considered as a good candidate for topical delivery of AsP.

  • PDF

PWR 1차계통내 해체 방사성선원항 평가방법에 관한 연구 (A Study on Radioactive Source-term Assessment Method for Decommissioning PWR Primary System)

  • 송종순;김현민;이상헌
    • 방사성폐기물학회지
    • /
    • 제12권2호
    • /
    • pp.153-164
    • /
    • 2014
  • 현재 전 세계적으로 설계단계에서 부식 생성물과 방사성 핵종의 양을 예측하는 프로그램에 대해서는 개발되거나 개발중인 프로그램이 다양하다. 그러나 원자력 발전소 해체 시 발생하는 방사화 부식생성물의 양을 평가하는 코드에 대한 개발은 이루어지지 않고 있어 정확한 산정에 어려움이 있다. 원자로 용기, 원자로 구성품 및 인접 구조물에서의 특성 원소의 중성자 조사로 인한 방사화재고량을 평가하기 위해서는 원자로의 고정된 구조물을 대표하는 모든 영역에서의 평균 중성자속과 구조물의 물질조성 및 원자로 운전이력 등을 이용하여 평가해야 한다. 본 논문에서는 설계단계에서 사용되는 1차 계통의 부식생성물과 방사성 핵종의 양을 예측하는 CORA, PACTOLE, CRUDSIM, CREAT 및 ACE 코드를 분석하였다. 향후 연구에서는 제염해체 폐기물 발생량 평가에 대한 사용가능성과 개선점을 찾아 부식생성물량 산정에 정확성을 높이고자 한다.

낙동강 하구호에서의 인의 용출특성 (Release Characteristics of Phosphorus in Nakdong Estuary Barrage)

  • 양진우;송교욱;이석모
    • 한국수산과학회지
    • /
    • 제23권3호
    • /
    • pp.192-197
    • /
    • 1990
  • 낙동강 하구호의 수질관리 모델링을 위한 인자중의 하나를 구하기 위해 하구호내의 저층 적물로부터의 인의 용출특성에 대한 연구를 수행하였다. 저질에 존재하는 POP와 PIP의 총인에 대한 존재비율은 각각 $34.7\%,\;65.7\%$이었고, 대부분의 PIP 는 NAI-P($61.1\%$)와 Apatite-P($30.0\%$)의 형태로 존재하였다. 회분식 반응조를 이용하여 수온과 용존산소의 환경조건에 따라 산출한 인의 용출속도는, 높은 수온과 혐기적 조건에서는 $39.4mg/m^2/d$로 저질로부터 많은 양이 용출되며, 낮은 수온과 호기적 조건에서는 $-4.4mg/m^2/d$로 수층으로 부터 제거되는 것으로 나타났다. 이상의 결과에서 낙동강 하구호내의 저질이 인의 내부부하원으로 작용할 가능성이 매우 크며 하구호의 인 농도 증가에 직접적인 영향을 끼치고 있음을 알 수 있다.

  • PDF

PHYSICAL PROPERTIES OF THE GIANT H II REGION G353.2+0.9 IN NGC 6357

  • BOHIGAS JOAQUIN;TAPIA MAURICIO;ROTH MIGUEL;RUlZ MARIA TERESA
    • 천문학회지
    • /
    • 제37권4호
    • /
    • pp.281-284
    • /
    • 2004
  • Optical imaging and spectroscopy of G353.2+0.9, the brightest part of the giant H II region NGC 6357, shows that this H II region is optically thin, contains ${\~}300\;M_{\bigodot}$ of ionized gas and is probably expanding into the surrounding medium. Its chemical composition is similar to that found in other H II regions at similar galactocentric distances if temperature fluctuations are significant. The inner regions are probably made of thin shells and filaments, whereas extended slabs of material, maybe shells seen edge-on, are found in the periphery. The radio continuum and H$\alpha$ emission maps are very similar, indicating that most of the optical nebula is not embedded in the denser regions traced by molecular gas and the presence of IR sources. About $10^{50}$ UV photons per second are required to produce the H$\beta$ flux from the 1l.3'${\times}$10' region surrounding the Pis 24 cluster that is south of G353.2+0.9. Most of the energy powering this region is produced by the 03-7 stars in Pis 24. Most of the 2MASS sources in the field with large infrared excesses are within G353.2+0.9, indicating that the most recent star forming process occured within it. The formation of Pis 24 preceded and caused the formation of this new generation of stars and may be responsible for the present-day morphology of the entire NGC 6357 region.

융제법에 의한 RIG 단결정 육성 (Growth of RIG Single Crystals by Flux Technique)

  • 김성현;이석희;정수진
    • 한국세라믹학회지
    • /
    • 제26권4호
    • /
    • pp.459-470
    • /
    • 1989
  • Single crystals of rare-earth iron garnets were grown from solutions of molten lead oxide, lead fluoride, baric oxide, iron oxide, and the oxides of yttrium, samarium orgadolinium. The crystals were grown by slow cooling technique. A convenient composition was 41.8mol% PbO, 20.59mol% PbF2, 8.23mol% B2O3, 20.00mol% Fe2O3 and 10.00mol% R2O3 where R is Y, Sm or Gd. For this experiment, platinum crucibles of size 20, 30cc and a vertical siliconit tube furnace were used. The precipitation temperature of YIG was observed in the range of 115$0^{\circ}C$-112$0^{\circ}C$ and the optimum growth conditions in this experiment were determined. The nucleation rate was controlled by the holding time after the fast colling, the growth rate by the slow cooling conditiions. The form of the grown YIG crystals showed a combination of {110} and {211}, and the size of the crystals grown in this experiment was up to about 9mm under the conditions of holding time 16hour, cooling rate 2$^{\circ}C$/hr. and temperature range 115$0^{\circ}C$-90$0^{\circ}C$. The precipitatin temperature of SmIG was observed in the range of 105$0^{\circ}C$-98$0^{\circ}C$ and the size of the crystals grown in this experiment was up to about 5mm under the conditiions of holding time 16hours, cooling rate 2$^{\circ}C$/hr. and temperature range 100$0^{\circ}C$-80$0^{\circ}C$.

  • PDF

Fe-Zr-N 연자성 박막의 자기적 성질 (Magnetic Properties of Fe-Zr-N Soft Magnetic Thin Films)

  • 김택수;김종오;이중환;윤선진;김좌연
    • 한국자기학회지
    • /
    • 제6권5호
    • /
    • pp.317-322
    • /
    • 1996
  • RF magnetron reactive sputtering 법으로 Fe-Zr-N 박막을 제작하여 열처리 온도와 질소 분압의 변화에 따른 포화자화, 보자력, 고주파에서의 투자율 그리고 열적 안정성을 조사하였다. Fe-Zr-N 박막은 비정질과 결정질의 경계 조성인 $Fe_{72-78}Zr_{7-10}N_{15-18}$의 조성범위에서 연자성을 나타내었다. 이러한 박막은 포화자속밀도 1.55 T, 1 MHz에서의 실효 투자율은 3000 이상의 연자성을 나타내고 열처리 온도 $550^{\circ}C$ 까지도 실효투자율 2500 정도의 열적 안정성을 나타내었다. X-선 회절 분석 결과 열처리에 의해서 ZrN 미결정이 석출하여 $\alpha-Fe$ 결정 성장이 억제되어 우수한 연자기적 성질이 나타난다고 판단된다. 이때 $\alpha-Fe$ 입자 크기는 $40~50\AA$, ZrN의 입자 크기는 $10~15\AA$이었다.

  • PDF

미분탄 순산소 연소에서 주위 기체와 석탄 특성이 화염전파에 미치는 영향 (Influence of Surrounding Gas and Coal Characteristics on Flame Propagation in Oxy-Fuel Combustion of Pulverized Coal)

  • 강영민;심영삼;문철언;성연모;서상일;김태형;최경민;김덕줄
    • 대한기계학회논문집B
    • /
    • 제33권1호
    • /
    • pp.38-45
    • /
    • 2009
  • Oxy-fuel combustion of pulverized coal is one of the promising new technologies to reduce $CO_2$ and NOx from coal combustion. However, the stability of pulverized coal flame is reduced in the oxy-fuel combustion. This flame stability is concerned with the flame propagation that is affected by surrounding gas and coal characteristics, such as gas temperature, gas composition, coal volatile, coal activation energy and coal size. In this paper, a study on the influence of surrounding gas and coal characteristics on the flame propagation velocity in oxy-fuel combustion of pulverized coal was preformed. One dimensional model was used to calculate the flame propagation velocity of pulverized coal clouds. In this model, the radiation is considered to be the main source of heat exchange, and Monte Carlo method was adopted for accurate calculation of radiation heat flux. It was found that the flame propagation velocity become higher with the decrease of coal activation energy and the increase of coal volatile. Also, according to the increase of gas temperature and $O_2$ concentration, flame propagation velocity increased.

고체연료 램젯용 HTPB 연료그레인에 첨가제와 점화보조제가 미치는 영향 (Effects of Additives and Ignition Support Material on HTPB Fuel Grains for Solid Fuel Ramjet)

  • 정우석;백승관;정연수;권태수;박주현;김인철;권세진
    • 한국추진공학회:학술대회논문집
    • /
    • 한국추진공학회 2017년도 제48회 춘계학술대회논문집
    • /
    • pp.957-967
    • /
    • 2017
  • 첨가제와 점화 보조제가 적용된 고체연료 램젯 용 연료 그레인의 연소시험을 수행하여 점화 지연과 연소 효율을 확인하였다. 연료 그레인은 HTPB에 AP 파우더 15 wt.% 보론 입자 5 wt.%가 혼합된 형태로 구성되어 있다. 연료 그레인에 $NC/BKNO_3$와 Composite 추진제로 이루어진 점화보조제를 도포하여 우수한 점화성능을 확보하였다. 에탄올 블렌딩 과산화수소 가스발생기를 통해 램젯 연소실의 공기와 가깝도록 온도, 압력, 산소 조성을 조절한 산화제 가스를 유속 $200kg/m^2s$ 으로 흐르도록 설정하였다. 실험 결과, 점화보조제의 작동을 통해 연료그레인에서 0.5초의 점화 지연시간을 파악하였다. 또한 보론의 연소를 통해 8 bar의 일정한 연소실 압력과 0.86의 높은 연소 효율을 확인하였다.

  • PDF

구봉석회석광산의 지질조사보고(地質調査報告) (Geologic Report on the Goobong Limestone Mine)

  • 이대성
    • 자원환경지질
    • /
    • 제3권1호
    • /
    • pp.17-24
    • /
    • 1970
  • The purpose of this report is to prepare a data for the economic evaluation on the Goobong Limestone Mine which is located at the south-eastern corner of the Yongchun Quadrangle scaled in 1:50,000. The accessibility from the mine to railroad was considered in two ways. One is to Dodam Station on Central Railway Line and the other is to reach Songjung-ni village which is near Sangyong Station on Hamback Railway Line. The distance of the former way is 26.7km and the later is 24.2km. Geologically the mine is situated near the base of the Greast Limestone Series which strikes generally $N25^{\circ}{\sim}30^{\circ}E$. The series comprises six different formations from older to younger; Pungchon Limestone Formation and Whajol Formation of Cambrian age, and Dongjum Quartzite Formation, Dumudong Formation, Maggol Limestone Formation and Goseong Formation of lower to middle Ordovician age. 82 samples; 48 from Pungchon Limestone Formation, 11 from Dumudong Formation, 15 from Maggol Limestone Formation and 8 from Goseong Formation, were taken from the series in the crossed direction to the general trend of the series as shown in geological map. They were chemically analyzed on the components of CaO, MgO, $SiO_2$, $R_2O_3(Al_2O_3+Fe_2O_3)$ and ignition loss as shown in table 2, table 3, table 4, and table 5. As seen from the tables, among the formations of the series, middle to upper parts of the Pungchon Limestone Formation and middle and upper parts of the Dumudong Formation have chemical composition as available source for the raw material of cement industry, not only that but also the part of the Pungchon Formation was highly evaluated as source for the flux of iron smelting and the raw material of carbide manufacturing because of its high purity of calcium carbonate.

  • PDF

강원도 영서지역 출토 분청사기의 조성 및 미세구조 분석: 원주(原州) 법천사지(法泉寺址)를 중심으로 (Compositional and microstructural analyses of grayish-blue-powdered celadon in Yeongseo Region in Gangwon-do:by Wonju Beopcheon-temple site)

  • 이병훈;소명기
    • 분석과학
    • /
    • 제26권3호
    • /
    • pp.211-221
    • /
    • 2013
  • 본 연구는 원주 법천사지에서 출토된 분청사기의 화학조성과 미세조직, 결정상을 X-선형광분석기와 주사전자현미경-에너지분산형엑스선분석기, X-선회절분석기를 이용하여 알아보았다. 태토의 화학성분 분석 결과, 낮은 실리카($RO_2$) 함량과 높은 융제(RO+$R_2O$) 함량임을 알 수 있다. 유약의 경우 융제 성분 중 CaO 함량이 높은 전형적인 석회계열(lime type)과 석회-알칼리 계열(lime-alkali type) 유약을 사용하였으며 태토의 결정상으로는 quarts, mullite, microcline, albite가 확인되었다. 특히 원주 법천사지에서 출토된 분청사기 태토의 화학적 조성은 제겔식을 이용하여 이미 연구된 다른 유적에서 출토된 분청사기와 비교하였으며 화학조성은 서로 상이한 결과를 보였다.