Oh, Won Sup;Choi, Jin;Kim, Yong Su;Do, Yong Hee;Jang, Tae Won;Jung, Maan Hong
Tuberculosis and Respiratory Diseases
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v.44
no.1
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pp.85-92
/
1997
Background : The standard treatment of recurrent, symptomatic malignant pleural effusion is intrapleural instillation of a chemical agent in an attempt to achieve a sterile inflammation and pleurodesis. There are many drugs used as pleural sclerosing agents, but the efficiency and side effects are different. The present study was undertaken to compare the commonly used drugs, doxycycline and bleomycin. Methods : Thirty-four patients with malignant pleural effusion who needed repeated thoracentesis were randomized to receive treatment with intrapleural instillation of doxycycline or bleomycin Fluid volumes before and after pleurodesis, drainge time, and side effects were analyzed, and the response to treatment was evaluated by clinical examination and chest radiography during admission in the hospital. Also median survival rime were evaluated according to the responses. Results : The response rate was higher in the patients receiving doxycycline than in those receiving bleomycin (87.5% vs 50.0%, p=0.02), and fever, nausea and vomiting were more common in the patients receiving bleomycin. The median survival time was significantly longer in the patients who responded to the sclerotherapy regardless of sclerosing agents. Conclusions : Chemical pleurodesis with doxycycline or bleomycin could reduce or stop pleural effusions and prolong the median survival rimes in these patients. Doxycycline appeared to be more efficient as sclerosing agent than bleomycin in the short-term follow-up periods. But a prospective study with a larger number of patients is warranted.
Kim, Jun-Gyu;Lee, In-bok;Yoon, Kwang-Sik;Ha, Tae-hwan;Kim, Rack-woo;Yeo, Uk-hyeon;Lee, Sang-yeon
Journal of Bio-Environment Control
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v.27
no.2
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pp.147-157
/
2018
With the rapid development of the 4th industrial revolution, the large-sized facilities of agriculture have been developed with high-technologies. However, it is difficult to maintain the optimum environment in large-sized facilities. Although it is essential to control micro-climate properly in large-sized facilities, there are a lot of problems to utilize high-technologies and equipment because of insufficient education for farmers. Most farms have limitations to access to their farm because of prevention of epidemics, exposure of management know-how, and so on. Especially, it is difficult to understand internal environmental factors (airflow, temperature, humidity, etc.) for farmers because these factors are invisible. Recently, Virtual reality technology which allows users to experience various phenomena directly is attracting attention. Virtual reality is very useful technology to visualize airflow and temperature distribution and so on. However, there is no cases applied this technology to agricultural facilities. In this study, research trends of virtual reality in various fields were investigated. In particular, the limitation and possibility of virtual reality technology were analyzed for educating farmers. Finally, the development of virtual reality contents for smart-farm facility were suggested.
In this study, PCDD/PCDFs, PAHs and PCBs in wastes from metal, plastic and wastewater treatment facilities were analyzed. The concentrations of PCDD/PCDFs ranged from 7.37~432.20 ng-TEQ/kg in fly ash, 0.51~855.01 ng-TEQ/kg in incinerated ash and 0.37~385.81 ng-TEQ/kg in dust. Dioxin content was lower, compared to data in foreign countries. PAHs concentration was in the range of 0.0075~2.9225 mg/kg for process sludge and 0.0035~1.6716 mg/kg for wastewater sludge, which satisfied all of the two standards (Nap, Ant, B(a)F:4/0.8, Phen, B(a)A:5/1, Flt:10/2.5, B(a)P:4.5/0.9) of the Marine Environment Management Act. PAHs concentration in process sludge and wastewater sludge were slightly lower than those abroad. According to the analysis of seven types of PCBs (in comparison with the first standard, 0.15 mg/kg), concentration was found in the range of 0.0~0.65 mg/kg, while PCB-52, PCB-101, PCB-138, PCB-153 and PCB-180 isomers were detected in excessive value in some machine oil and hydraulic fluid.
A case is reported of a man with malignant fibrous histiocytoma (MFH) in right thigh who developed streptococcal toxic shock syndrome (STSS) during postoperative radiotherapy. Before radiotherapy, a patient complained wax and wane lymphedema following wide excision of tumor mass which was confirmed as MFH. He took some nonsteroidal antiinflammatory drug (NSAID) for about one month. He suffered preexisting hepatitis C virus (HCV) infection, diabetes and well-controlled hypertension. The patient received conventional radiotherapy to right thigh with a total dose of 32.4 Gy at 1.8 Gy per day. At last radiotherapy fraction, cutaneous erythematous inflammation was suddenly developed at his affected thigh. At that time, he also complained of oliguria, fever and chills. The patient was consulted to internal medicine for adequate evaluation and management. The patient was diagnosed as suggested septic shock and admitted without delay. At admission, he showed hypotension, oliguria, constipation, abnormal renal and liver function. As a result of blood culture, Streptococcus pyogenes was detected. The patient was diagnosed to STSS. He was treated with adequate intravenous antibiotics and fluid support. STSS is one of oncologic emergencies and requires immediate medical intervention to prevent loss of life. In this patient, underlying HCV infection, postoperative lymphedema, prolonged NSAID medication, and radiotherapy may have been multiple precipitating factors of STSS.
In this study, a long-term unsteady simulation model has been developed using rigid water column theory which is more accurate than Extended-period model and more efficient comparing with water-hammer simulation model. The developed model is applied to 24-hours unsteady simulation considering daily water-demand and water-hammer analysis caused by closing a valve. For the case of 24-hours daily simulation, the pressure of each node decreases as the water demand increase, and when the water demand decrease, the pressure increases. During the simulation, the amplitudes of flow and pressure variation are different in each node and the pattern of flow variation as well as water demand is quite different than that of KYPIPE2. Such discrepancy necessitates the development of unsteady flow analysis model in water distribution network system. When the model is applied to water-hammer analysis, the pressure and flow variation occurred simultaneously through the entire network system by neglecting the compressibility of water. Although water-hammer model shows the lag of travel time due to fluid elasticity, in the aspect of pressure and flow fluctuation, the trend of overall variation and quantity of the result are similar to that of water-hammer model. This model is expected for the analysis of gradual long-term unsteady flow variations providing computational accuracy and efficiency as well as identifying pollutant dispersion, pressure control, leakage reduction corresponding to flow-demand pattern, and management of long-term pipeline net work systems related with flowrate and pressure variation in pipeline network systems
Although there are many possible mechanisms for the intrinsic seismic attenuation in composite materials that include fluids, relative motion between solids and fluids during seismic wave propagation is one of the most important attenuation mechanisms. In our previous study, we conducted ultrasonic wave transmission measurements on an ice-brine coexisting system to examine the influence on ultrasonic waves of the unfrozen brine in the pore microstructure of ice. In order to elucidate the physical mechanism responsible for ultrasonic wave attenuation in the frequency range of 350.600 kHz, measured at different temperatures in partially frozen brines, we employed a poroelastic model based on the Biot theory to describe the propagation of ultrasonic waves through partially frozen brines. By assuming that the solid phase is ice and the liquid phase is the unfrozen brine, fluid properties measured by a pulsed nuclear magnetic resonance technique were used to calculate porosities at different temperatures. The computed intrinsic attenuation at 500 kHz cannot completely predict the measured attenuation results from the experimental study in an ice-brine coexisting system, which suggests that other attenuation mechanisms such as the squirt-flow mechanism and wave scattering effect should be taken into account.
Background: Spontaneous hemopneumothorax, occurring in 1% to 12% of patients with spontaneous pneumothorax, is a rare disorder that can potentially lead to life-threatening complications. Materials and methods: We have experienced 15 cases (2.28%) with spontaneous hemopneumothorax among 659 episodes of spontaneous pneumothorax for eight years, from 1990 to 1997, at our hospital. We studied our previously treated patients by retrospective case studies to determine the nature of optimal management. Results: There were 14 male and 1 female patients whose mean age was 27.5 years, ranging from 19 to 58. The sides with disorder were as following: right in 10 cases and left in 5, unilaterally. The amount of initial bleeding ranged from 400 to 1,500 mL and 8 patients received a homologous blood transfusion. Patients exhibited symptoms of chest pain, dyspnea, chest discomfort, and hypovolemic shock. We concluded that causes of this disease in our patients were a torn pleural adhesion (14 cases) and a rupture of vascularized bullae (1 case with an underlying intrinsic lung disease, tuberculosis). All patients underwent closed thoracostomy and had good results except for 3. One patient underwent thoracotomy within 3 days from the onset because of continuous active hemorrhage. Decortication was required in one case because of a reactive fluid collection in the pleural space, which led to impaired lung expansion. Another patient underwent thoracotomy due to a ipsilateral recurrent pneumothorax without blood collection. Conclusions: The goals of treatment include hemostasis and reexpansion of the collapsed lung. Thus, if patients arrive early at hospital, closed thoracostomy and transfusion are thought to be sufficient treatments, although early surgical repair has been considered recently.
Hwang Seho;Shim Jehyun;Park Inhwa;Choi Sun Young;Park Ki Hwa;Koh Gi Won
한국지구물리탐사학회:학술대회논문집
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2005.09a
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pp.55-71
/
2005
Jeju Island is mainly composed of basaltic lava flows and subordinate amounts of volcaniclastic sedimentary rocks. Jeju Province operates the monitoring wells for seawater intrusion problems around Jeju Island to evaluate of groundwater resources in coastal area. Various surveys and monitoring have been performed in boreholes, and also conventional geophysical well loggings conducted to identify basalt sequences and assess seawater intrusion problems. Various conventional geophysical well logs, including radioactive logs, electrical log, caliper log, and temperature and conductivity log and heat-pulse flowmeter log were obtained in 29 boreholes. The results of geophysical well loggings for saturated rocks are interesting and consistent. Natural gamma logs are useful in basalt sequences to sedimentary interbeds, unconsolidated U formation, and seoguipo formation with higher natural gamma log regardless of saturated or unsaturated basalts. Neutron logs are very effective to discriminate among individual lava flows, flow breaks, and sedimentary interbeds in saturated formation. In hyalocastite, porosity is high and resistivity is low, and we think that hyalocastite is a major pathway of fluid flow. In trachybasalt, porosity has a wide range and resistivity is high. In sedimentary interbeds, unconsolidated U formation and seoguipo formation, porosity is high and resistivity is low. The temperature logs in eastern area in Jeju are useful to interpret the hydrogeological unit and evaluate seawater intrusion in Suan area.
Lee, In Soo;Choi, Hwan Jun;Lee, Han Jung;Lee, Jae Wook;Lee, Dong Gi
Archives of Plastic Surgery
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v.36
no.3
/
pp.351-355
/
2009
Purpose: Cervical necrotizing fasciitis tends to involve the deep soft tissues and spread caudally to the anterior chest and mediastinum, often resulting in major complications and death. It may rapidly spread into the thorax along fascial planes, and the associated diagnostic delay results in this descending necrotizing mediastinitis. So, aggressive multidisciplinary therapy with surgical drainage is mandatory. We present a very rare case of descending necrotizing mediastinitis with literature review. Methods: A 53 years old male visited our department 7 days after trauma in neck. His premorbid conditions and risk factors of necrotizing fasciitis were concealed hepatoma, trauma history, chronic liver disease, and nutrition deficit. Computed tomographic scans of the head and neck region were performed in this patient : signs of necrotizing fasciitis, were seen in the platysma, sternocleidomastoid, trapezius muscle and strap muscles of the neck. Fluid accumulations involved multiple neck spaces and mediastinum. At the time, he diagnosed as necrotizing fasciitis on his neck and anterior chest. Necrotic wound was excised serially and we treated this with the Vacuum - assisted closure(VAC, Kinetics Concepts International, San Antonio, Texas) system device. After appropriately shaping the sponge and achieving additional 3 pieces drainage tubes in the pockets, continuous negative pressure of 125 mmHg was applied. The VAC therapy was utilized for a period of 12 days. Results: We obtained satisfactory results from wide excision, abscess drainage with the VAC system, and then split thickness skin graft. The postoperative course was uneventful. Conclusion: The refined technique using the VAC system can provide a means of simple and effective management for the descending necrotizing mediastinitis, with better cosmetic and functional results. Finally, the VAC system has been adopted as the standard treatment for deep cervical and mediastinal wound infections as a result of the excellent clinical outcome.
Background: This study was undertaken to evaluate the clinical pattern of the patients with penetrating torso injury. We retrospectively analyzed the clinical symptoms, mechanism of injury, injury type including injured organ, and ultimate outcome of treatment. Our purpose of the study was to establish guideline of management in penetrating torso injury. Methods: This study consists of an analysis of a consecutive series of 94 patients with penetrating injury of trunk treated at one general hospital during 7year period (from January 1995 to April 2003) who was admitted through in our emergency department. All data were collected from the medical records and entered in a database for analysis on the following: age, sex, mechanism of injury, vital sign at admission, clinical outcome including hospital mortality, length of hospital stay, length of intensive care unit stay, requirement of crystalloid fluid and blood product. Results: Among 94 patients, there were 68 men and 26 women, with ages ranging from 19 to 82 years (average 38.2 years). The most frequent mechanism of injury was violence by others including rob (n=54, 57.4%) followed by suicidal attempt (n=24, 25.5%) and accidental injury (n=16, 17.0%). No injury was inflicted from gun. In 37 patients, systolic blood pressure at admission was under 90mmHg. The time interval from injury to admission, and from admission to operation was 57.8minutes and 4hour 12minutes each. Laparotomy was required in 70 patients, thoracotomy in 5 patients, and 3 patients required thoracotomy and laparotomy. Among 94 patients, an average of 1.7 organs were injured. The small bowel and colon were the organs most commonly wounded followed by liver, mesentery, pleura. Of the 94 patients, 6 died for an overall mortality rate of 6.4%, and two of them were not related with hemorrhage. The average length of hospital stay was 18.1 days, and 40 patients required ICU care. Conclusion: Of the 94 patients who were admitted from penetrating torso injury, no patient was injured from firearm. Overall mortality rate was 6.4%. In our hospital, firearm injury was relative rare.
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