• The Journal of Internal Korean Medicine
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• v.41 no.6
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• pp.1052-1065
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• 2020

Objectives: To evaluate the reliability of a pattern identification tool for benign prostatic hyperplasia and to examine the relationship between pattern identification tool readings and IPSS and uroflowmetry. Methods: We analyzed 56 patients diagnosed with benign prostatic hyperplasia from December 27th, 2017 to December 26th, 2018 by two different Korean medical doctors and followed with a pattern identification tool and by IPSS and uroflowmetry. One week later, the patients were retested to analyze the reliability of the pattern identification tool, determined with the intraclass correlation coefficient (ICC) using the test-retest method. The correlation between IPSS and uroflowmetry was analyzed with the Pearson coefficient. Result: The reliability of the pattern identification tool for benign prostatic hyperplasia was evaluated as "poor agreement beyond chance" (ICC=0.349). The reliability of each pattern identification score was evaluated as "good" for Yang Deficiency of Kidney, Yin Deficiency of Kidney, Deficiency of Middle Qi, and Dampness-heat of Lower Energizer. The internal consistency was evaluated as "good" for Yang Deficiency of Kidney, Yin Deficiency of Kidney, and Dampness-heat of Lower Energizer, and as "excellent" for Deficiency of Middle Qi. The correlation between pattern identification and IPSS was evaluated as a "moderate positive correlation" for all pattern identifications. The average flow rate and maximum flow rate using uroflowmetry was evaluated with "moderate negative correlation" for Yang Deficiency of Kidney and Dampness-heat of Lower Energizer. Conclusion: The reliability of a pattern identification tool for benign prostatic hyperplasia was evaluated as "poor agreement beyond chance." Further research is needed.

• Aerospace Engineering and Technology
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• v.8 no.2
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• pp.140-148
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• 2009

MOV(Main Oxidizer shut-off Valves) control the combustion of launch vehicle systems by the supply and the isolation of liquid oxygen to a main combustion chamber in launch vehicle systems. Moreover, in the steady operational state, the MOV should secure a constant flow rate of liquid oxygen for combustion instability in the combustion chamber. Concerning the development of MOV, TM(Technology Model) has been manufactured and normal operations of the valve have been verified. However, the Cv of TM has been proved to be too low as compared with a design specification value. Therefore, CFD analysis have been performed by modification of the configurations of TM in order to increase sufficiently Cv of EM(Engineering Model), which is the following model of TM. The modifications of TM configurations such as partial scale-up of valve, increase of stroke length, and outlet angle of 120o would result in a considerable augmentation of Cv. It has been verified by flow capacity tests that the improved Cv of EM is min. 212, which is higher than Cv of TM, 161 by about 32%.

• Applied Chemistry for Engineering
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• v.10 no.2
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• pp.310-318
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• 1999

The concentration breakthrough curves were examined to predict mass transfer coefficients of nitrogen and oxygen in adsorption column for design data of PSA process. Experimental breakthrough curves for bulk gas flow were compared with theoretical simulation results. For quantitative analysis of the adsorption, coupled Langmuir isotherm was considered and LDF model was used to describe the mass transfer effect. In the experimental and theoretical results, it was found that mass transfer coefficient was not affected by flow rate but strongly affected by pressure. As a result of this tendency, mass transfer resistance in this system was proved to belong to the macropore diffusion controlling region and the mass transfer coefficients could be expressed by exponential functions of pressure change. The mass transfer coefficients for one component, nitrogen or oxygen, were successfully applied to breakthrough curves for bulk mixed gases. The experimental curves were reasonably in consistent with the theoretical curves and the error time was less than 5 percent.

• Nuclear Engineering and Technology
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• v.28 no.1
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• pp.56-71
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• 1996

The local hydrulic characteristics in subchannels of 5$\times$5 nuclear fuel bundles with spacer grids were measured at upstream and downstream of the spacer grid for the investigation of the spacer grid effects on turbulent flow structure by using an LDV(Laser Doppler Velocimeter). The measured parameters are axial velocity and turbulent intensity, skewness factor, and flatness factor. Pressure drops were also measured to evaluate the loss coefficient for the spacer grid and the friction factor for rod bundles. From these data, it was found that the turbulent mixing and forced mixing occur up to $x/D^h=10$ and 20 from the spacer grid, respectively. The turbulence decay behind spacer grid behaves in the similar decay rate as turbulent flow through mesh grids or screens. Mixing factors useful in subchannel analysis code were correlated from the data and show the highest value near spacer grid and then have a stable values.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.25 no.2
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• pp.94-100
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• 2013

A convergent-divergent nozzle or venturi nozzle has been used to accelerate the wind speed at its throat. The wind speed at the throat is inversely proportional to its area according to the continuity equation. In this numerical study, an airflow phenomena in the venturi system placed at a vertical structure was investigated to understand the vortex effect occurred at the rear-side of the vertical structure on the air speed increment at the throat of the venturi system. For this study, a venturi system sized by $20(m){\times}20(m){\times}6(m)$ was modelled and the area ratio(AR) of the model venturi was 2.86. To see the vortex effect on the air flow acceleration in the venturi throat, two different boundary conditions was defined From the study, it was found that the pressure coefficient(CP) of the venturi system with the vortex formed at the exit of the venturi was about 2.5times of the CP of the venturi system without the vortex effect. The velocity increment rate of the venturi system with the vortex was 61% but 9.5% only at the venturi system without the vortex. Conclusively, it can be said that the venturi system installed in a vertical structure has very positive effect on the flow acceleration at its throat due to the vortex formed at the rear-side of the vertical structure.

• Journal of the Korean Institute of Gas
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• v.11 no.3
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• pp.19-25
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• 2007

The heat transfer phenomena in a coil-typed LPG vaporizer with a hot water bath employed an electrical heating system were experimentally analyzed. The heat energy is initially used to sensible heat region to heat LPG and then is done to latent heat region to vaporize LPG and to heat up the vaporized gas. A two-phase flow region could be found from periodic temperature fluctuations, and only sensible heat effect was found after passing through the region. The overall heat capacity was defined as multiplying the overall heat transfer coefficient by the heat transfer area and we found a correlation employing the heating water temperature and LPG flow rate. The results of this work can effectively be applied for the design of field scale LPG vaporizers in the near future because they can predict the features of heat transfer on a kind of coil type LPG vaporizer.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.19 no.1
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• pp.33-39
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• 1983

Tidal exchange of sea water was studied by using drogue experiments and tidal current measurement data in Yeoja Bay which has a narrow channel. At the spring tide, the volume of tidal transport in the bay was estimated to be 43% of the mean volume of the sea water in Yeoja Bay, 1.96km super(3). Residual current was deduced to flow southward at the rate of 3,658$\times$10 super(4) m super(3) per tidal cycle. The mean tidal exchange of sea water during the flood flow was estimated to be approximately 5.0% of the volume of sea water at the mean high water level in the bay, 2.33km super(3), while that during the ebb flow was 6.3%. One dimensional diffusion coefficient of 1.69-1.97$\times$10 super(6) cm super(2)/sec was obtained at the channel in the bay.

• Journal of the Korean Society of Marine Environment & Safety
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• v.25 no.1
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• pp.130-137
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• 2019

In this study, a centrifugal seawater cooling pump was analyzed to investigate its cavitation behavior over different operating flow rates. 3D two-phase simulations were carried out with ANSYS-CFX commercial code. The $k-{\varepsilon}$ turbulence and Rayleigh-Plesset cavitation models were employed in the simulations. A head drop characteristics curves for three discharge rates was built based on numerical predictions. At higher flow rates, the impeller was more vulnerable to bubble cavitation. The 3 % head drop points of the pump working at 0.7Q, Q, and 1.3Q (Q: design flow rate) corresponded with NPSHa 1.21 m, 1.83 m, and 3.45 m, respectively. The volume of vapor bubbles was estimated and cavitation locations were anticipated to visualize the development of the cavity within the impeller. Moreover, the distribution of pressure coefficient and a blade loading chart are specifically presented, bringing out the harmful impacts of cavitation on the pump operation.

• Nuclear Engineering and Technology
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• v.26 no.4
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• pp.516-525
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• 1994

Since the TMI and Chernobyl accidents, many passive safety features are suggested in advanced reactors in order to enhance the safety in future nuclear power plants. In order to verify the effectiveness and provide the data for detailed design of passive cooling system, in the present work, the effects of air inlet position and external condition on the natural circulated air flow rate and the natural and forced convective heat transfer coefficient have been investigated for the one-side heated closed path such as the passive containment cooling system of the Westinghouse's AP-600. A series of experiments have been peformed with the 1/26th scaled segment type test facility of the AP-600 passive containment. Under natural and forced convection, the air velocities and temperatures are measured at several points of the air flow path. The experimental result are compared with a simple one-dimensional model and it shows a good agreement.

• Journal of Pharmaceutical Investigation
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• v.35 no.3
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• pp.137-142
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• 2005

A rapid, selective and sensitive reversed-phase HPLC method for the determination of glipizide in human serum was validated and applied to the pharmacokinetic study of glipizide. Glipizide and internal standard, tolbutamide, were extracted from human serum by liquid-liquid extraction with benzene and analyzed on a Nova Pak $C_{18}\;60{\AA}$ column with the mobile phase of acetonitrile-potassium dihydrogen phosphate (10 mM, pH 3.5) (4:6, v/v). Detection wavelength of 275 nm and flow rate of 0.7 ml/min were fixed for the study. The assay robustness for the changes of mobile phase pH, organic solvent content, and flow rate was confirmed by $3^3$ factorial design using a fixed glipizide concentration (500 ng/ ml) with respect to its peak area and retention time. And also, the ruggedness of this method was investigated at three different laboratories using same quality control (QC) samples. This method showed linear response over the concentration range of 10-1000 ng/ml with correlation coefficient greater than 0.999. The lower limit of quantitation using 0.5 ml of serum was 10.0 ng/ml, which was sensitive enough for pharmacokinetic studies. The overall accuracy of the quality control samples ranged from 82.6 to 105.0% for glipizide with overall precision (% C.V.) being 1.13-13.20%. The percent recovery for human serum was in the range of 85.2 93.5%. Stability studies showed that glipizide was stable during storage, or during the assay procedure in human serum. The peak area and retention time of glipizide were not significantly affected by the changes of mobile phase pH, organic solvent content, and flow rate under the conditions studied. This method showed good ruggedness (within 15% C.V.) and was successfully used for the analysis of glipizide in human serum samples for the pharmacokinetic studies at three different laboratories, demonstrating the suitability of the method.