• Korean Chemical Engineering Research
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• 제57권5호
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• pp.735-742
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• 2019

이온 선택성 표면이 가지는 파상구조와 전기와류 불안정성 간의 전기동역학적 상호작용을 수치해석을 통하여 연구하였다. 유한요소법을 이용하여 전기장-이온 이동현상-유동장을 완전결합 해석을 하였다. 이를 통해 파상구조가 제공하는 전기와류 생성 기작인 Dukhin's mode의 유효성 및 역할을 제시하였다. Runinstein's mode와 경쟁관계에 놓이는 Dukhin's mode는 (i) 과한계 영역으로의 전이 전압을 낮춰주고 (ii) 혼돈계인 과한계 영역에서 전류를 비선형적으로 증가시켜준다. 또한, (iii) 전기와류 불안정성에서 발생하는 비효율적 혼합의 원인인 고주파수 Fourier 성분을 배제하여 전기와류의 혼합 효율을 상승시켜 준다. 결론적으로, 본 연구에서 제시한 기작은 전기투석, 화학전지 등의 이온 선택성 이동현상 시스템에 대한 에너지 효율적인 기작으로 활용 가능할 것이다.

• The Journal of Korean Physical Therapy
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• 제32권6호
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• pp.383-387
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• 2020

Purpose: The purpose of the present study was to investigate the effects of a simultaneous dual-task and horse-riding simulator (HRS) training regime on pulmonary function and flexibility. Methods: Sixteen subjects were recruited and randomly allocated to two groups: a dual-task (DT) (n=8) or a single-task (ST) (n=8) training group. Flexibility and pulmonary function were assessed before and after HRS training. Both groups underwent HRS training for 4 weeks, 3 times/week in 15-minute training sessions. The ST group underwent HRS training and the DT group underwent dual-task HRS training, which consisted of throwing and catching a ball and ring catching while HRS training. Results: Training significantly increased flexibility and FVC (forced vital capacity) and FEV1 (forced expiratory volume in 1 second) in both groups (p<0.05), but FEV1/FVC and PEF (peak expiratory flow) were not significantly different after training in both groups (p>0.05). After the training, flexibility and FVC in the DT group were significantly greater than in the ST group (p<0.05), but FEV1, FEV1/FVC, and PEF were not significantly different (p>0.05). Conclusion: Simultaneous dual-task and HRS motor training improved flexibility, FVC, and FEV1, and our comparative analysis suggests that dual-task HRS training improved flexibility and FVC more than single-task training.

• Advances in aircraft and spacecraft science
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• 제10권5호
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• pp.419-437
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• 2023

This paper presents the study of the effects of rigid-body motion simultaneously with the presence of the effects of temporal variation due to the existence of morphing speed on the aeroelastic stability of the two-stage telescopic wings, and hence this is the main novelty of this study. To this aim, Euler-Bernoulli beam theory is used to model the bending-torsional dynamics of the wing. The aerodynamic loads on the wing in an incompressible flow regime are determined by using Peters' unsteady aerodynamic model. The governing aeroelastic equations are discretized employing a finite element method based on the beam-rod model. The effects of rigid-body motion on the length-based stability of the wing are determined by checking the eigenvalues of system. The obtained results are compared with those available in the literature, and a good agreement is observed. Furthermore, the effects of different parameters of rigid-body such as the mass, radius of gyration, fuselage center of gravity distance from wing elastic axis on the aeroelastic stability are discussed. It is found that some parameters can cause unpredictable changes in the critical length and frequency. Also, paying attention to the fuselage parameters and how they affect stability is very important and will play a significant role in the design.

• Nuclear Engineering and Technology
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• 제35권5호
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• pp.426-441
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• 2003

A reactor inlet header break experiment, B9401, performed in the RD-14M multi channel test facility was analyzed using RELAP5/MOD3.2 and RELAP5/CANDU[1]. The RELAP5 has been developed for the use in the analysis of the transient behavior of the pressurized water reactor. A recent study showed that the RELAP5 could be feasible even for the simulation of the thermal hydraulic behavior of CANDU reactors. However, some deficiencies in the prediction of fuel sheath temperature and transient behavior in athe headers were identified in the RELAP5 assessments. The RELAP5/CANDU has been developing to resolve the deficiencies in the RELAP5 and to improve the predictability of the thermal-hydraulic behaviors of the CANDU reactors. In the RELAP5/CANDU, critical heat flux model, horizontal flow regime map, heat transfer model in horizontal channel, etc. were modified or added to the RELAP5/MOD3.2. This study aims to identify the applicability of both codes, in particular, in the multi-channel simulation of the CANDU reactors. The RELAP5/MOD3.2 and the RELAP5/CANDU analyses demonstrate the code's capability to predict reasonably the major phenomena occurred during the transient. The thermal-hydraulic behaviors of both codes are almost identical, however, the RELAP5/CANDU predicts better the heater sheath temperature than the RELAP5/MOD3.2. Pressure differences between headers govern the flow characteristics through the heated sections, particularly after the ECI. In determining header pressure, there are many uncertainties arisen from the complicated effects including steady state pressure distribution. Therefore, it would be concluded that further works are required to reduce these uncertainties, and consequently predict appropriately thermal-hydraulic behaviors in the reactor coolant system during LOCA analyses.

• 대한조선학회논문집
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• 제50권6호
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• pp.399-406
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• 2013

In the present study, the flat plate model test method is developed to evaluate the skin friction of the marine coating in the cavitation tunnel. Six-component force balance is used to measure the profile drag of the flat plate and strut. LDV(laser Doppler velocimetry) technique is also employed to evaluate the drag and to figure out the reason of the drag reduction. The flow velocities above the surface can be used to assess the skin friction, combined with direct force measurement. Since the vortical structure in the coherent turbulence structure influences on the skin friction in the high Reynolds number regime, the interaction between the turbulence structure and the surface wall is paying more attention. This sort of thing is important in the passive control of the turbulent boundary layer because the skin friction can't be determined only by wall condition. As complicated flow phenomena exist around a paint film, systematic measurement and analysis are necessary to evaluate the skin friction appropriately.

• Nuclear Engineering and Technology
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• 제22권1호
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• pp.12-19
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• 1990

1981년 6월 9일 고리 1호기 원자력발전소에서 발생한 외부 전원 상실사고 자료를 근거로 RELAP5/MOD2코드모델 평가를 하였다. 계산된 주요 열ㆍ수력학 변수를 실측자료와 비교 분석하였으며 증기발생기의 Nodalization 민감도 분석이 수행되었다. 계산된 열ㆍ수력학 변수는 실측치와 비교적 잘 일치하고 있으며, 이러한 유형의 사고 분석에 RELAP5/MOD2가 적합하다는 것을 보였다. 그러나 가압기 압력과 수위변동에서는 상당한 차이를 보였으며 높게 계산되었다. 이러한 사실은 RELAP5의 수직관에서의 층류 열전달 모델에 기인하는 것으로 해당모델의 개선을 요하고 있다는 것을 알았다. 그리고 증기발생기의 Nodalization 연구를 통하여 수위변동을 잘 예측하기 1위해서는 증기발생기 증기 Dome와 Downcomer사이에 압력을 전달시켜주는 유로를 모델링 하여야 한다는 것을 알았다.

• 한국수자원학회논문집
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• 제42권10호
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• pp.773-783
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• 2009

강우유출모형의 입력 자료로 사용되는 강우 관측 자료의 불확실성이 유량예측에 미치는 영향을 분석하기 위하여 모형변수 검정의 불확실성 연구에서 사용하는 GLUE (Generalized Likelihood Uncertainty Estimation)방법을 입력 자료 부분으로 확장하여 적용 하였다. 독일의 Weida 유역의 강우 관측 자료를 바탕으로 구조적 및 비구조적인 불확실성 부분을 각각 구조적인 오차 수정 과정과 DUE (Data Uncertainty Engine)을 통하여 강우자료를 구성하였다. 이를 유역의 수문학적 작용을 고려하기 위해 선정한 집중형 강우유출모형, PDM (Probability Distribution Model)에 MC (Monte Carlo)와 GLUE 방법을 활용하여 적용하였다. MC검정변수들의 검정 후 반응 표면(Posterior response surface)을 검토하고 GLUE 의 반응검정 모형변수(Behavioural model parameter set)를 선택, 간략한 GLUE 유량곡선들을 계산하였다. 계산된 GLUE 유량곡선들을 모두 합하여 앙상블 유량을 산정하고, 이 유량의 90 분위를 강우량자료 및 모형변수 검정의 불확실성을 고려한 신뢰구간으로 제시하였다. PDM 모형의 결과는 유량곡선의 전구간에서 안정적인 모의 능력을 보여주고 있으나, 첨두유량 부분이 적게 산정되는 문제점을 보이고 있다. 본 연구에서 상대적으로 적은 수의 강우 시나리오 및 반응검정 모형변수의 적용이라는 한계에도 불구하고, GLUE 방법을 강우관측자료의 불확실성 부분으로 확장하여 강우자료 및 변수 검정의 불확실성을 고려한 모의된 유량예측의 신뢰구간의 적용가능성을 보여주고 있다.

• 한국안전학회지
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• 제32권4호
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• pp.34-39
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• 2017

Typical flow regime of overflow at barrier or weir constructed in mid and small streams becomes as the submerged flow during most flood events. One of major causes of barrier failure has been reported as the levee-scour near the conjuction node between barrier and levee. However, most related design guidelines in Korea have not mentioned about the protection of levee around barrier or weir in detail. Furthermore, most previous researches have focused on the flow characteristics of overflow around several types of weirs but they did not have considered the material properties of levee itself. In this study, local scour near barrier was investigated with different material properties of levee under the submerged overflow condition which is assumed to reenact a flood event. Based on results from Fritz et al. and Mavis et al., a theoretical formula was also proposed in initial stage of laboratory experiments. And hydraulic experiments were carried out for the verification of the proposed formula. Levee was installed in the prismetic trapezoidal open channel and most parts were made of concrete except for movable section in which scour was expected to occur for the efficiency of experimental procedure. Each compaction of movable section in levee was followed by the basis of the KS F 2312. Further, after performing the experiments to find the optimum water content for each sediment, the specific amount of water was injected before flowing water. The difference between the proposed theoretical formula and experiment results was not much but considerable, which might be caused by the effect of compaction. For theoretical approach, it seemed that the formula did not take into account the compaction of levee, thus the correction coefficient for levee compaction determined in the literature was considered. Finally, the formula for the length of scour around barrier or weir was proposed, which can be useful to predict a levee in the reference design of revetment in mid and small streams. As shortly future study, scour length of levee around barrier or weir under different flow conditions such as perfect overflow condition will be studied and it will be able to contribute to suggest the design formula or criteria under all overflow conditions near barrier or weir.

• Environmental Analysis Health and Toxicology
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• 제27권
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• pp.10.1-10.7
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• 2012

Objectives: In recent years, a number of structurally diverse Histone deacetylase (HDAC) inhibitors have been identified and these HDAC inhibitors induce growth arrest, differentiation and/or apoptosis of cancer cells in vitro and in vivo. This study aimed at investigating the antitumor activity of newly synthesized HDAC inhibitor, 3-(4-dimethylamino phenyl)-N-hydroxy-2-propenamide (IN-2001) using human breast cancer cells. Methods: We have synthesized a new HDAC inhibitor, IN-2001, and cell proliferation inhibition assay with this chemical in estrogen receptor-positive human breast cancer MCF-7 cells. Cell cycle analysis on MCF-7 cells treated with IN-2001 was carried out by flow cytometry and gene expression was measured by RT-PCR. Results: In MCF-7 cells IN-2001 showed remarkable anti-proliferative effects in a dose- and time-dependent manner. In MCF-7 cells, IN-2001 showed a more potent growth inhibitory effect than that of suberoylanilide hydroxamic acid. These growth inhibitory effects were related to the cell cycle arrest and induction of apoptosis. IN-2001 showed accumulation of cells at $G_2$/M phase and of the sub-$G_1$ population in a time-dependent manner, representing apoptotic cells. IN-2001-mediated cell cycle arrest was associated with HDAC inhibitor-mediated induction of CDK inhibitor expression. In MCF-7 cells, IN-2001 significantly increased $p21^{WAF1}$ expression. Conclusions: In summary, cyclin-dependent kinase (CDK) induced growth inhibition, possibly through modulation of cell cycle and apoptosis regulatory proteins, such as CDK inhibitors, and cyclins. Taken together, these results provide an insight into the utility of HDAC inhibitors as a novel chemotherapeutic regime for hormone-sensitive and insensitive breast cancer.

• 스마트미디어저널
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• 제9권4호
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• pp.44-51
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• 2020

1990년대 중후반 이래 북한경제에 많은 변화가 나타나는 것은 분명하다. 2012년 김정은 집권 이후 그 변화는 더욱 뚜렷하게 나타나고 있기 때문에 시기별 경제정책 흐름을 추적하여 변화추이를 파악하는 데 논문의 목적이 있다. 본 논문에서는 텍스트마이닝 분석기법인 LDA 토픽모델링을 활용하여 북한에서 발간되는 경제 분야 대표문헌인 경제학술지 『경제연구』 논문을 분석한다. 『경제연구』에 게재된 논문을 기본 텍스트로 활용하여 북한 경제 전략과 정책변화를 파악한다. 북한에서 생산되는 경제 관련 학술지로 독보적 위치를 차지하고 있는 『경제 연구』에 대한 심층 분석은 북한 당국이 경제 관련 인식하고 있는 현실, 직면 하고 있는 한계, 대안 등을 추적하는데 필수적인 작업이라고 할 수 있다. 다양한 북한 경제 관련 논쟁 주제가 숨어있는 『경제연구』를 빅데이터를 통해 분석하여 북한 지도자의 경제정책 흐름을 살펴보고, 현 김정은 체제가 의도하는 '변화'의 내용을 분석한다.