• Toxicological Research
• /
• v.29 no.2
• /
• pp.115-120
• /
• 2013

To investigate the effects of short-term exposure of beryllium on the human immune system, the proportion of T-lymphocytes such as CD3+, CD4+, CD8+, CD95, and NK cells, and the proportion of B cells and $TNF{\alpha}$ level in peripheral blood and immunoglobulins in the serum of 43 exposed workers and 34 healthy control subjects were studied. External exposure to beryllium was measured by atomic absorption spectrometer as recommended by the NIOSH analytical method 7300. T lymphocyte subpopulation analysis was carried out with flow cytometer. The working duration of exposed workers was less than 3 months and the mean ambient beryllium level was $3.4{\mu}g/m^3$, $112.3{\mu}g/m^3$, and $2.3{\mu}g/m^3$ in molding (furnace), deforming (grinding), and sorting processes, respectively (cited from Kim et al., 2008). However, ambient beryllium level after process change was non-detectable (< $0.1{\mu}g/m^3$). The number of T lymphocytes and the amount of immunoglobulins in the beryllium-exposed workers and control subjects were not significantly different, except for the total number of lymphocytes and CD95 (APO1/FAS). The total number of lymphocytes was higher in the beryllium-exposed individuals than in the healthy control subjects. Multiple logistic regression analysis showed lymphocytes to be affected by beryllium exposure (odd ratio = 7.293; p<0.001). These results show that short-term exposure to beryllium does not induce immune dysfunction but is probably associated with lymphocytes proliferation.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.19 no.5
• /
• pp.1-8
• /
• 2018

In this study, a small-scale siphon breaker experimental facility was designed to examine the validity of the Siphon Breaker Simulation Program (SBSP). To design the experimental facility, the simulation results of the C factor, Chisholm B coefficient, and Undershooting Height (UH) were obtained by SBSP. The major parts of the experimental facility were the upper tank, lower tank, downcomer, and Siphon Breaker Line (SBL). The area of the Upper tank was $0.09-m^2$ with a height of 0.65-m. The height of the downcomer was 1.6-m. Pressure transmitters and an electronic scale were used to obtain the experimental results. The experimental variables were the sizes of Loss of Coolant Accident (LOCA) and SBL. The experimental results were analyzed by UH. The SBSP well predicted the UH with an error of 2.5%. Overall, it is possible to design siphon breakers with various scales using SBSP.

• Proceedings of the KOSOMBE Conference
• /
• v.1997 no.05
• /
• pp.92-94
• /
• 1997

By measuring the increase of regional cerebral blood flow (rCBF) during the activation tasks, we can describe the brain regions that participate in certain specific functions. In this study, we composed the functional maps of verbal and nonverbal memory by performing the rCBF positron emission tomography (PET) activation studies and analyzing the differences between control and each activation state. Successive four tasks, which consist of one control state and three different activation tasks, were performed on 6 normal volunteers. All images were spatially normalized on standard atlas and the differences between control and activation states were statistically analyzed. The verbal memory activated predominantly left-sided structures, especially left superior temporal cortex, and the nonverbal short-term memory activated the right frontal cortex. Also, some regions ,where is thought to be related with short-term memory system, such as cingulate gyrus and hippocampus were activated. We conclude that biological validity of the brain regions for verbal and nonverbal memory could be tested using rCBF PET imaging technique and statistical analysis.

• Journal of Acupuncture Research
• /
• v.15 no.2
• /
• pp.301-310
• /
• 1998

Infrared thermographic imaging visualizes noninvasively various abnormal condition by detecting the skin temperature. As the imaging represents the objective condition by the changes in blood flow under the control of autonomic nervous system, it is used to diagnosis and monitor the lumboscral radiculopathy. And asymmetry is important in the diagnosis of disc herniation. The most common type of disc herniation occurs psoterolaterally. This frequently causes nerve root compression leading to a radiculopathy in the distribution of the involved nerve root, most of which also provoke the asymmetric changes in thermography. Central disc herniation, which accounts for 5% to 35% of disc herniation, is typically associated with low back pain. But radiculopathy is usually abscent unless central disc heriniaton is large enough to cause compression of the cauda equina. To evalute the diagnostic value of the thermographic imaging in the diagnosis of central disc herniation, the imaging of 15 normal subjects and 48 patients with central disc herniation documented by CT scan were analyzed. The patients had either bilateral radiculophathy or no radiculopathy. The imaging of patient group with non rediculopathy did not show any significant thermal difference to control. While bilateral radiculopathy group reveled hypothermic pattern compared twith control. Thermal difference between left and right side did not present any significance in non radiculopathy group but hypothermia in bilateral radiculopathy group. Large herniation group demonstrated hyperthemic pattern while the others showed no significant change. Cranial caudal thermal difference did not show any difference between experiment groups. These results shows that infrared thermographic imaging can be used central disc herniation with bilateral radiculopathy, while it seems to little useful on the diagnosis of non radiculopathic disc herniation.

• Proceedings of the Korean Society of Propulsion Engineers Conference
• /
• 2006.11a
• /
• pp.377-381
• /
• 2006

This paper describes experimental work to control supersonic jet noise using a mesh screen that is placed at the nozzle exit plane. The mesh screen is a wire-gauze screen that is made of long stainless wires with a very small diameter. The nozzle pressure ratio is varied to obtain the supersonic jets which are operated in a wide range of over-expanded to moderately under-expanded jets. In order to perturb mainly the initial jet shear layer, the hole is perforated in the central part of the mesh screen. The hole size is varied to investigate the noise control effectiveness of the mesh screen. A schlieren optical system is used to visualize the flow fields of supersonic jet with and without the mesh screen device. Acoustic measurement is performed to obtain the OASPL and noise spectra. The results obtained show that the present mesh screen device leads to a substantial suppression of jet screech tones. The hole size is an important factor in reducing the supersonic jet noise. For over-expanded jets, the noise control effectiveness of the mesh screen appears more significant, compared to correctly and under-expanded jets

• Proceedings of the KSME Conference
• /
• 2000.11b
• /
• pp.371-376
• /
• 2000

In this study, the computational method is presented to simulate the hemodynamics of the patients after the Fontan procedure. The short-term feedback control models are implemented to assess the hemodynamic responses of the patients exposed to the stresses such as gravitational effect or hemorrhage. To construct the base line of the Fontan model, we assume an increase in venous tone, in heart rates, and in systemic resistance that are based on the clinical observations. For the verification of the present method we simulate the LBNP (lower body negative pressure) test for the normal and the Fontan model and we compare these with experimental data. Computational results show that the diastolic ABP(arterial blood pressure) increases but the systolic ABP decreases during LBNP. The increase in heart rate is due to the control system activated by the decreased mean ABP and CVP(central venous pressure). In case of the Fontan model, the increased venous tone is the reason of the diminished CVP change during LBNP. We also simulate 20% hemorrhage stress to the patient after the Fontan procedure and these results are compared with the experimental and the existing computational one. Computational results on the hemodynamics of patients after the Fontan procedure show that the mean ABP and cardiac output decrease. Heart rate and systemic resistance increase to compensate for the decrease in ABP. The sensitivity analysis according to the conduit resistance is also presented to delineate the effects of the local blood flow resistance. The cardiac output decreases according to the increase of the conduit resistance. The 50% increase in the conduit resistance causes about 3% decrease of cardiac output.

• Korean journal of food and cookery science
• /
• v.11 no.3
• /
• pp.249-260
• /
• 1995

6 Central commissary and 2 conventional school foodservice operations were assessed in terms of time-temperature relationship and microbiological quality, and monitoring control methods were identified through hazard analysis during the phases of prodution and distribution. 2 conventional schools from Seoul and 6 commissary schools from Kyungkido were participated in the survey. Meals produced in central commissary were distributed to satellites, therefore delivery practices of foods were identified as critical. Microbiological test results for commissary and conventional schools revealed that microbiological quality of foods was mainly related to time-temperature management, types of food, and equipment sanitation not to the foodservice system used. Time-temperature profiles at temperature danger zone (7.2-60$^{\circ}C$) observed were to be related to the following sanitary practices: cooked vegetables were held at temperature danger zone for relatively longer delayed time (15-38$^{\circ}C$: 15-226 min, 7-60$^{\circ}C$: 75-226 min), and same results were observed for deep-fat fried cutlets (15-38$^{\circ}C$: 15-151 min, 7-60$^{\circ}C$: 33-151 min). Menu items with various ingredients and frequent contacts with hands and equipments during the production flow were held at temperature danger zone for longer delaying time than other menu items with brief prodution stages. Based on hazard analysis critical control points, microbiological quality was collectively affected by time-temperature relationships, equipment sanitation, proper cooking methods, and sanitary management competencies of dietitians. Microbiological test results of working equipments and surface of dishes and trays showed that immediate action should be taken. Cutting boards used in central kitchen were also showed similar results of potential dager of cross-contamination. Effective sanitary control methods were urgently needed.

• Journal of the Korean Society of Propulsion Engineers
• /
• v.18 no.3
• /
• pp.8-16
• /
• 2014

This paper analyzes the effects of sideslip angle(SA) on the buzz margin of supersonic intake. The buzz margin is assumed to be stabilized by a controller which generates command depending only on the longitudinal sensor measurements. The analysis is performed based on three dimensional CFD results with which the sensor measurements can be simulated. In such a control system based on the longitudinal measurements, unexpected lateral flow perturbation results in the increase in the total angle of attack(TAoA), that causes the degradation of the engine intake performance. As a consequence, it is shown that the control stability is reduced such that additional control margin needs to be secured.

• Journal of the Korean Institute of Intelligent Systems
• /
• v.24 no.6
• /
• pp.609-614
• /
• 2014

Cerebellar ataxia is a steadily progressive neurodegenerative disease associated with loss of motor control, leaving patients unable to walk, talk, or perform activities of daily living. Direct motor instruction in cerebella ataxia patients has limited effectiveness, presumably because an inappropriate closed-loop cerebellar response to the inevitable observed error confounds motor learning mechanisms. Recent studies have validated the age-old technique of employing motor imagery training (mental rehearsal of a movement) to boost motor performance in athletes, much as a champion downhill skier visualizes the course prior to embarking on a run. Could the use of EEG based BCI provide advanced biofeedback to improve motor imagery and provide a "backdoor" to improving motor performance in ataxia patients? In order to determine the feasibility of using EEG-based BCI control in this population, we compare the ability to modulate mu-band power (8-12 Hz) by performing a cued motor imagery task in an ataxia patient and healthy control.

• Journal of Navigation and Port Research
• /
• v.32 no.10
• /
• pp.771-776
• /
• 2008

The main purpose in having a control surface on a ship is to control the motion of it. It is the important element to determine the maneuvering characteristics of the ship. In this paper, the measured results has been compared with each other to predict the performance characteristics of flapped rudder's 2-dimensional section at $Re=3.0{\times}10^4$ using 2-frame grey level cross correlation PIV method. The side force of the rudder could be mainly improved by the lift force at 10 degrees angle of attack and the drag force at 20 degrees angle of attack. The separation point and boundary layer could be controlled by the change of the only flap's angle at 10 degrees angle of attack.