• Title/Summary/Keyword: Fixed Effect Analysis

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The Optimization of Reconstruction Method Reducing Partial Volume Effect in PET/CT 3D Image Acquisition (PET/CT 3차원 영상 획득에서 부분용적효과 감소를 위한 재구성법의 최적화)

  • Hong, Gun-Chul;Park, Sun-Myung;Kwak, In-Suk;Lee, Hyuk;Choi, Choon-Ki;Seok, Jae-Dong
    • The Korean Journal of Nuclear Medicine Technology
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    • v.14 no.1
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    • pp.13-17
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    • 2010
  • Purpose: Partial volume effect (PVE) is the phenomenon to lower the accuracy of image due to low estimate, which is to occur from PET/CT 3D image acquisition. The more resolution is declined and the lesion is small, the more it causes a big error. So that it can influence the test result. Studied the optimum image reconstruction method by using variation of parameter, which can influence the PVE. Materials and Methods: It acquires the image in each size spheres which is injected $^{18}F$-FDG to hot site and background in the ratio 4:1 for 10 minutes by using NEMA 2001 IEC phantom in GE Discovey STE 16. The iterative reconstruction is used and gives variety to iteration 2-50 times, subset number 1-56. The analysis's fixed region of interest in detail part of image and compute % difference and signal to noise ratio (SNR) using $SUV_{max}$. Results: It's measured that $SUV_{max}$ of 10 mm spheres, which is changed subset number to 2, 5, 8, 20, 56 in fixed iteration to times, SNR is indicated 0.19, 0.30, 0.40, 0.48, 0.45. As well as each sphere's of total SNR is measured 2.73, 3.38, 3.64, 3.63, 3.38. Conclusion: In iteration 6th to 20th, it indicates similar value in % difference and SNR ($3.47{\pm}0.09$). Over 20th, it increases the phenomenon, which is placed low value on $SUV_{max}$ through the influence of noise. In addition, the identical iteration, it indicates that SNR is high value in 8th to 20th in variation of subset number. Therefore, to reduce partial volume effect of small lesion, it can be declined the partial volume effect in iteration 6 times, subset number 8~20 times, considering reconstruction time.

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Cytotoxicity of Multipurpose Contact Lens Solutions on the Cultured Corneal Epithelial Cells Evaluated by Image Analysis (이미지 분석법을 이용한 소프트 콘택트렌즈용 다목적용액의 각막상피세포 독성 평가)

  • Kim, Nam-Youl;Lee, Koon-Ja
    • Journal of Korean Ophthalmic Optics Society
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    • v.20 no.1
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    • pp.51-60
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    • 2015
  • Purpose: To determine the effect of marketed multipurpose contact lens solutions (MPSs) on human corneal epithelial cells (HCEpiCs) toxicity by using image analysis. Methods: HCEpiCs were exposed six MPSs (product A-F) at 0.05~50% for 2h, 12h, 24h, and 48h respectively. HCEpiCs were fixed and stained with Draq5 after exposure with MPSs, and the cell viability and apoptosis were evaluated by using confocal microscope and ImageXpress UltraTM. Results: Viabilities of HCEpiCs exposed to MPS A-F for a 2h were not affected, while reductions (52~75%) in cell viability over a 12h exposure of MPS B, MPS C, MPS D and MPS F, and significant more reductions (29~73%) over a 24h and 48h-exposure. Apoptosis of HCEpiC was not affect over a 12h MPS exposure, however was significantly increased (199~526%) over 24h and 48h MPS exposure. Among the products MPS D, E and F reduced viability of HCEpiCs and apoptosis increased more than MPS A (p<0.05). Conclusions: Lower concentration of MPSs have not an cytotoxic effect on HCEpiCs, however higher concentration of MPSs induce apoptosis and reduce viability of HCEpiCs. Therefore, it need to develop MPS having antimicrobial effectiveness with low cytotoxicity.

An Analysis on Signal Control Efficiency in a Three-Leg Intersection Adopting Pedestrian Push-Button System Following Pedestrian volume (3지 교차로에서 보행자 교통량에 따른 보행자작동신호기를 이용한 신호제어효율에 관한 분석)

  • Kim, Eung-Cheol;Cho, Han-Seon;Jung, Dong-Woo;Kim, Hyoung-Soo
    • International Journal of Highway Engineering
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    • v.11 no.3
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    • pp.121-128
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    • 2009
  • This study has proposed the signal operating system to use both semi-actuated signal control and pedestrian push-button as a way to make up for the problems of 3 leg intersections which are operated inefficiently in the signal operation, one of the methods of traffic operations. In case of the semi-actuated signal control, it can reduce delay inside the intersection by serving to uncongested traffic on the main road where there is not much traffic volume on the secondary road and push-button signal can reduce unnecessary waiting time it could happen to vehicles by operating it though there is no pedestrian. Quantitative analysis was tried regarding the average delay reduction per vehicle using VISSIM, microscopic simulation program regarding how much effect it has compared with the existing signal control system and semi-actuated signal control system when the above two advantages are collected. The field test was performed for one three-leg intersection of Incheon. According to respectively signal control method pedestrian traffic changed and executed a sensitivity analysis. The result which compares the average delay time per a vehicle of scenarios, the signal control method of using the pedestrian push-button system in comparison with the fixed signal control method showed to decrease effect of a minimum 3.7 second (10%), a maximum 5.8 second (16%). When the pedestrian traffic volume was 20% or less of the measurement traffic volume, The signal control method of using the pedestrian push-button system appeared to be more efficient the semi-actuated signal control with object intersection.

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Weighting Effect on the Weighted Mean in Finite Population (유한모집단에서 가중평균에 포함된 가중치의 효과)

  • Kim, Kyu-Seong
    • Survey Research
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    • v.7 no.2
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    • pp.53-69
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    • 2006
  • Weights can be made and imposed in both sample design stage and analysis stage in a sample survey. While in design stage weights are related with sample data acquisition quantities such as sample selection probability and response rate, in analysis stage weights are connected with external quantities, for instance population quantities and some auxiliary information. The final weight is the product of all weights in both stage. In the present paper, we focus on the weight in analysis stage and investigate the effect of such weights imposed on the weighted mean when estimating the population mean. We consider a finite population with a pair of fixed survey value and weight in each unit, and suppose equal selection probability designs. Under the condition we derive the formulas of the bias as well as mean square error of the weighted mean and show that the weighted mean is biased and the direction and amount of the bias can be explained by the correlation between survey variate and weight: if the correlation coefficient is positive, then the weighted mein over-estimates the population mean, on the other hand, if negative, then under-estimates. Also the magnitude of bias is getting larger when the correlation coefficient is getting greater. In addition to theoretical derivation about the weighted mean, we conduct a simulation study to show quantities of the bias and mean square errors numerically. In the simulation, nine weights having correlation coefficient with survey variate from -0.2 to 0.6 are generated and four sample sizes from 100 to 400 are considered and then biases and mean square errors are calculated in each case. As a result, in the case or 400 sample size and 0.55 correlation coefficient, the amount or squared bias of the weighted mean occupies up to 82% among mean square error, which says the weighted mean might be biased very seriously in some cases.

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Effects of implant alignment and load direction on mandibular bone and implant: finite element analysis (임플란트 배열과 하중 방향이 임플란트와 치조골에 미치는 유한요소 응력분석)

  • Chung, Hyunju;Park, Chan;Yun, Kwi-Dug;Lim, Hyun-Pil;Park, Sang-Won;Yang, Hongso
    • Journal of Dental Rehabilitation and Applied Science
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    • v.36 no.3
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    • pp.176-182
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    • 2020
  • Purpose: To evaluate the effects of load direction, number of implants, and alignment of implant position on stress distribution in implant, prosthesis, and bone tissue. Materials and Methods: Four 3D models were made to simulate posterior mandible bone block: two implants and 3-unit fixed dental prosthesis (FDP) with a pontic in the center (model M1), two implants and 3-unit FDP with a cantilever pontic at one end (model M2), FDP supported by three implants with straight line placement (model M3) and FDP supported by three implants with staggered implant configuration (model M4). The applied force was 120 N axially or 120 N obliquely. Results: Peak von Mises stresses caused by oblique occlusal force were 3.4 to 5.1 times higher in the implant and 3.5 to 8.3 times higher in the alveolar bone than those stresses caused by axial occlusal force. In model M2, the connector area of the distal cantilever in the prosthesis generated the highest von Mises stresses among all models. With the design of a large number of implants, low stresses were generated. When three implants were placed, there were no significant differences in the magnitude of stress between staggered arrangement and straight arrangement. Conclusion: The effect of staggering alignment on implant stress was negligible. However, the number of implants had a significant effect on stress magnitude.

The Analysis of Hysteresis in Youth Unemployment (청년실업의 이력현상 분석)

  • Kim, Namju
    • Economic Analysis
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    • v.25 no.2
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    • pp.96-131
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    • 2019
  • Initially entering into the job market during hard times with unfavorable market institutions has a persistent, negative effect on young workers' subsequent employment. This paper analyzes hysteresis in youth unemployment by using a composite fixed-effect panel data model. Data sets for the age-cohort unemployment rate and for labor market institutions are constructed from OECD statistics from 21 advanced economies, including Korea, from 1985 to 2017, and are then readjusted to match with the peculiarities of the Korean market. In Korea, with a less-aggressive stance on active labor market policy spending, a male worker who experiences a one percentage point higher youth unemployment rate when he was 20- to 29-years-old has a 0.146 percentage point higher unemployment rate at the ages of 30-to 34-years-old and a 0.035 percentage point higher unemployment rate at the age of 35- to 39-years-old. These figures are larger than those in most countries that have more aggressive spending schemes. These findings point out that hysteresis in the Korean labor market can be mitigated by expanding active labor market policy spending more aggressively and more effectively.

Development of Acquisition and Analysis System of Radar Information for Small Inshore and Coastal Fishing Vessels - Suppression of Radar Clutter by CFAR - (연근해 소형 어선의 레이더 정보 수록 및 해석 시스템 개발 - CFAR에 의한 레이더 잡음 억제 -)

  • 이대재;김광식;신형일;변덕수
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.39 no.4
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    • pp.347-357
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    • 2003
  • This paper describes on the suppression of sea clutter on marine radar display using a cell-averaging CFAR(constant false alarm rate) technique, and on the analysis of radar echo signal data in relation to the estimation of ARPA functions and the detection of the shadow effect in clutter returns. The echo signal was measured using a X -band radar, that is located on the Pukyong National University, with a horizontal beamwidth of $$3.9^{\circ}$$, a vertical beamwidth of $20^{\circ}$, pulsewidth of $0.8 {\mu}s$ and a transmitted peak power of 4 ㎾ The suppression performance of sea clutter was investigated for the probability of false alarm between $l0-^0.25;and; 10^-1.0$. Also the performance of cell averaging CFAR was compared with that of ideal fixed threshold. The motion vectors and trajectory of ships was extracted and the shadow effect in clutter returns was analyzed. The results obtained are summarized as follows;1. The ARPA plotting results and motion vectors for acquired targets extracted by analyzing the echo signal data were displayed on the PC based radar system and the continuous trajectory of ships was tracked in real time. 2. To suppress the sea clutter under noisy environment, a cell averaging CFAR processor having total CFAR window of 47 samples(20+20 reference cells, 3+3 guard cells and the cell under test) was designed. On a particular data set acquired at Suyong Man, Busan, Korea, when the probability of false alarm applied to the designed cell averaging CFAR processor was 10$^{-0}$.75/ the suppression performance of radar clutter was significantly improved. The results obtained suggest that the designed cell averaging CFAR processor was very effective in uniform clutter environments. 3. It is concluded that the cell averaging CF AR may be able to give a considerable improvement in suppression performance of uniform sea clutter compared to the ideal fixed threshold. 4. The effective height of target, that was estimated by analyzing the shadow effect in clutter returns for a number of range bins behind the target as seen from the radar antenna, was approximately 1.2 m and the information for this height can be used to extract the shape parameter of tracked target..

Comparative Analysis of Track-Bridge Interaction of Sliding Slab Track and Rail Expansion Joint for Long-Span Railway Bridge (장경간 철도 교량에 적용된 슬라이딩 궤도와 레일신축이음장치의 궤도-교량 상호작용 비교)

  • Lee, Kyoung Chan;Jang, Seung Yup;Lee, Jungwhee;Choi, Hyun Sung
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.29 no.2
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    • pp.169-177
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    • 2016
  • Sliding slab track system, which consists of low friction sliding layer between track slab and bridge deck, is recently devised to reduce track-bridge interaction effect of continuously welded rail(CWR) without applying special devices such as rail expansion joint(REJ). In this study, a series of track-bridge interaction analyses of a long-span bridge with sliding slab track and REJ are performed respectively and the results are compared. The bridge model includes PSC box girder bridge with 9 continuous spans, and steel-concrete composite girder bridge with 2 continuous spans. The total length of the bridge model is 1,205m, and the maximum spacing between the two fixed supports is 825m. Analyses results showed that the sliding slab track system is highly effective on interaction reduction since lower rail additional axial stress is resulted than REJ application. Additionally, horizontal reaction forces in fixed supports were also reduced compared to the results of REJ application. However, higher slab axial forces were developed in the sliding slab track due to the temperature load. Therefore, track slab section of the sliding slab track system should be carefully designed against slab axial forces.

Effect of the Application of Temporal Mask Map on the Relationship between NDVI and Rice Yield (시계열 마스크 맵이 논벼 NDVI와 단수와의 관계에 미치는 영향)

  • Na, Sang-il;Ahn, Ho-yong;Park, Chan-won;Hong, Suk-young;So, Kyu-ho;Lee, Kyung-do
    • Korean Journal of Remote Sensing
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    • v.36 no.5_1
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    • pp.725-733
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    • 2020
  • The objectives of this study were (1) to develop a temporal mask map using MCD12Q1 data, and (2) to extract the annual variations in paddy, (3) to investigate the correlation analysis between MYD13Q1 NDVI and rice yield, and (4) to review its applicability. For these purposes, the temporal mask map was created using annual MCD12Q1 PFT data from 2002 to 2019, and compared with the fixed mask map. As a result, it found that the temporal mask map well reflected the variations of the paddy area. In addition, the correlation coefficient between NDVI and rice yield was also high significant as compared to the fixed mask map. Therefore, the temporal mask map will be useful for NDVI extraction, crop monitoring, and estimation of rice yield.

Genome-wide Association Study to Identify Quantitative Trait Loci for Meat and Carcass Quality Traits in Berkshire

  • Iqbal, Asif;Kim, You-Sam;Kang, Jun-Mo;Lee, Yun-Mi;Rai, Rajani;Jung, Jong-Hyun;Oh, Dong-Yup;Nam, Ki-Chang;Lee, Hak-Kyo;Kim, Jong-Joo
    • Asian-Australasian Journal of Animal Sciences
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    • v.28 no.11
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    • pp.1537-1544
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    • 2015
  • Meat and carcass quality attributes are of crucial importance influencing consumer preference and profitability in the pork industry. A set of 400 Berkshire pigs were collected from Dasan breeding farm, Namwon, Chonbuk province, Korea that were born between 2012 and 2013. To perform genome wide association studies (GWAS), eleven meat and carcass quality traits were considered, including carcass weight, backfat thickness, pH value after 24 hours (pH24), Commission Internationale de l'Eclairage lightness in meat color (CIE L), redness in meat color (CIE a), yellowness in meat color (CIE b), filtering, drip loss, heat loss, shear force and marbling score. All of the 400 animals were genotyped with the Porcine 62K SNP BeadChips (Illumina Inc., USA). A SAS general linear model procedure (SAS version 9.2) was used to pre-adjust the animal phenotypes before GWAS with sire and sex effects as fixed effects and slaughter age as a covariate. After fitting the fixed and covariate factors in the model, the residuals of the phenotype regressed on additive effects of each single nucleotide polymorphism (SNP) under a linear regression model (PLINK version 1.07). The significant SNPs after permutation testing at a chromosome-wise level were subjected to stepwise regression analysis to determine the best set of SNP markers. A total of 55 significant (p<0.05) SNPs or quantitative trait loci (QTL) were detected on various chromosomes. The QTLs explained from 5.06% to 8.28% of the total phenotypic variation of the traits. Some QTLs with pleiotropic effect were also identified. A pair of significant QTL for pH24 was also found to affect both CIE L and drip loss percentage. The significant QTL after characterization of the functional candidate genes on the QTL or around the QTL region may be effectively and efficiently used in marker assisted selection to achieve enhanced genetic improvement of the trait considered.