• Title/Summary/Keyword: Fitness to work

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Bacterial Stringent Signal Directs Virulence and Survival in Vibrio cholerae.

  • Oh, Young Taek;Kim, Hwa Young;Yoon, Sang Sun
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2019.10a
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    • pp.8-8
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    • 2019
  • The stringent response (SR) is characterized as a bacterial defense mechanism in response to various growth-inhibiting stresses. It is activated by accumulation of a small nucleotide regulator, (p)ppGpp, and induces global changes in bacterial transcription and translation. Recent work from our group has shown that (p)ppGpp plays a critical role in virulence and survival in Vibrio cholerae. The genes, relA and relV, are involved in the production of (p)ppGpp, while the spoT gene encodes an enzyme that hydrolyzes it in V. cholerae. A mutant strain defective in (p)ppGpp production (i.e. ${\Delta}relA{\Delta}relV{\Delta}spoT$ mutant) lost the ability to produce cholera toxin (CT) and lost their viability due to uncontrolled production of organic acids, when grown with extra glucose. In contrast, the ${\Delta}relA{\Delta}spoT$ mutant, a (p)ppGpp overproducer strain, produced enhanced level of CT and exhibited better growth in glucose supplemented media via glucose metabolic switch from organic fermentation to acetoin, a neutral fermentation end product, fermentation. These findings indicates that (p)ppGpp, in addition to its well-known role as a SR mediator, positively regulates CT production and maintenance of growth fitness in V. cholerae. This implicates SR as a promising drug target, inhibition of which may possibly downregulate V. cholerae virulence and survival fitness. Therefore, we screened a chemical library and identified a compound that induces medium acidification (termed iMAC) and thereby loss of wild type V. cholerae viability under glucose-rich conditions. Further, we present a potential mechanism by which the compound inhibits (p)ppGpp accumulation. Together, these results indicate that iMAC treatment causes V. cholerae cells to produce significantly less (p)ppGpp, an important regulator of the bacterial virulence and survival response, and further suggesting that it has a therapeutic potential to be developed as a novel antibacterial agent against cholera.

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A Human Function Deployment for Managing Human Factor in Korea railroad (국내 철도시스템에서 기능전개를 통한 인적요소 관리방안 연구)

  • Heo, Eun-Mee;Kim, Sa-Kil;Byun, Seong-Nam
    • Proceedings of the KSR Conference
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    • 2009.05a
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    • pp.1376-1382
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    • 2009
  • Railway system is a word that includes rolling stock, railway infrastructure and signalling System in passenger transfer and rail freight. This system get higher competitiveness in energy efficiency part than other transfer system. But it is comprehensive system has latent loss of lives and property by big accident. First of all, to control this comprehensive system and to confirm safety of it, we need human resource management. This research will suggest how to apply efficiency safety verification and certification system to railway system. human resource management systems is defined as three kinds that is recruitment and management, ensure personnel's competencies and fitness, activity of assigning suitable responsible person for work.

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Effects of a High-Intensity Interval Training Program on the Fitness and Performance of Firefighters (고강도 인터벌 트레이닝(HIIT)이 소방공무원의 체력 및 업무능력에 미치는 영향)

  • Kim, Cherho;Ji, Changjin;Kim, Sangho
    • Fire Science and Engineering
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    • v.34 no.2
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    • pp.97-102
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    • 2020
  • The purpose of this study was to investigate the effectiveness of a Tabata exercise program as an alternative for firefighters whose working environment makes it difficult to manage physical fitness. The Tabata exercise program, in which 16 people participated, led to increased muscle mass and reduced weight and body fat, which not only improved the health of the firefighters but also improved their cardiopulmonary endurance, muscle endurance, and muscle strength, which are essential elements during firefighting emergency relief activities. On the basis of these results, it is believed that developing and providing guidelines for scientific and systematic exercise programs to firefighters will lead to better work capability during fire and disaster situations.

Health Status, Health Behavior, and Health Promotion Program Needs of Industrial Male Workers according to Shift Work at an Workplace (일개 산업장 남성 근로자의 근무형태별 건강상태와 건강행위 및 건강증진 프로그램 요구도)

  • Hwang, Seung-Sook
    • Research in Community and Public Health Nursing
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    • v.17 no.2
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    • pp.210-222
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    • 2006
  • Purpose: This study was performed to identify the health status, healthy behavior, and health promotion program needs of day time and shift time industrial male workers at an workplace. Method: Relevant data were collected from June 20 to August 18, 2005. Questionaries were distributed to all subjects along with their medical records of 2005 and 151 sets of responses were used for the analysis. Collected data were analyzed using SPSS WIN 10.0. Result: 1. Health Status - day time and shift-time workers had significant differences in obesity ($x^2=8.38$, p<.01) and blood pressure ($x^2=-2.17$, p<.05). 2. Healthy Habits - Full-time and part-time workers had significant differences in regular meals (63.83, p<.01), preferred foods ($x^2=7.10$, p<.05), and sleep time (t=-3.55, p<.01). They also had significant differences in exercising ($x^2=13.11$, p<.01), exercising time (minutes) (t=-2.25, p<.01), and use of fitness centers ($x^2=7.02$, p<.05). 3. They also had significant differences in their needs of health programs ($x^2=8.66$, p<.01). Conclusion: This study revealed that day time and shift-time workers had differences in obesity and blood pressure, as well as differences in eating sleeping, and exercising patterns. Both groups needed 'fitness programs' more than any other types of health programs and picked 'weight loss' and 'stress control' programs for other options. Industrial nurses should be able to create appropriate health programs for each group based on the above results and induce the workers' active participation.

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Female Workers' Uniform Preference of the Fiber Firms (섬유업체 근로여성의 작업복 실태 및 선호연구)

  • 이옥희
    • Journal of the Korean Home Economics Association
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    • v.35 no.4
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    • pp.185-198
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    • 1997
  • This study was initiated to research on the uniform preference uniform satisfaction and wearing of female workers' uniform of the fiber firms. Data was obtained from 361 female workers of the fiber firms in Chon Buk. And it was analyzed by frequency percent mean duncan's multiple test. The results of this study were as follows; 1) Pocket sleeve and front hem were parts of the damage. The weaving workers were mostly wore upper and under garments but most of there workers were only wore an upper garment on the basic type of uniform The older and married were small in the fitness of uniform the armhole sleeve girth sleeve length and breast girth were unfitted 2) Workers was dissatisfied to the noise and the dust in working environment. Uniform satisfaction of workers were mostly low design color and fabric were the lowest factors of uniform satisfaction. The satisfaction of material were also low the lowest factors were absorptiveness elasticity breathability. Workers wanted the fashion and light colored uniform but they prefered function activity to work and manageability on wearing rather than externals among the uniform preference.

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An intelligent fuzzy theory for ocean structure system analysis

  • Chen, Tim;Cheng, C.Y.J.;Nisa, Sharaban Tahura;Olivera, Jonathan
    • Ocean Systems Engineering
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    • v.9 no.2
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    • pp.179-190
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    • 2019
  • This paper deals with the problem of the global stabilization for a class of ocean structure systems. It is well known that, in general, the global asymptotic stability of the ocean structure subsystems does not imply the global asymptotic stability of the composite closed-loop system. The classical fuzzy inference methods cannot work to their full potential in such circumstances because given knowledge does not cover the entire problem domain. However, requirements of fuzzy systems may change over time and therefore, the use of a static rule base may affect the effectiveness of fuzzy rule interpolation due to the absence of the most concurrent (dynamic) rules. Designing a dynamic rule base yet needs additional information. In this paper, we demonstrate this proposed methodology is a flexible and general approach, with no theoretical restriction over the employment of any particular interpolation in performing interpolation nor in the computational mechanisms to implement fitness evaluation and rule promotion.

A Study on the Development of Low Back Pain and the Risk Factors of Manufacturing Workers (일부 제조업 근로자들의 요통유병률과 요인에 관한 조사)

  • Park, Am
    • Journal of Preventive Medicine and Public Health
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    • v.26 no.1 s.41
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    • pp.37-48
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    • 1993
  • This study was conducted to investigate the prevalence rate of low back pain during past one year and its risk factors. The data were collected from 1,384 manufacturing factory workers from March 1, 1992 to August 30, 1992. The results obtained were as follows: 1. The one year prevalence rate of low back pain by manufacturing company was 38.4% in textile manufacturing, 35.2% in concrete reenforcement, 31.0% in cigarette and 26.1% in metal part(P<0.01). 2. In textile manufacturing, age groups with high prevalence rate of low back pain were 30's(36.8%) and 40's(36.4%) (P<0.05), and the one year prevelence rates of low back pain by marital state were 34.9% in married workers and 28.5% in unmarried(P=0.0511). 3. The one year prevelence rates of low back pain by job part are 35.0% in labor workers and 26.1% in clerical(P<0.05), and by work hour per day it was 34.9% in 9 or more and 28.9% in 8 or less(P<0.05). 4. The highest group of low back pain by work posture was 43.5% in 'lifting and transfering materials', and it by fitness of chair was 56.0% in uncomfortable one, and by height of working board was 33.6% in low working one. 5. In logistic regression analysis, significant determinants with low back pain were marital state(p<0.05), work hour per day(P<0.05), height of working board(P<0.01), and work posture(P<0.01).

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Need Assessment for Worksite Health Promotion Program (산업장 근로자의 건강증진 프로그램 요구도)

  • Song, Yeon-ee;Jang, Jung Hee
    • Korean Journal of Occupational Health Nursing
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    • v.8 no.2
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    • pp.115-129
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    • 1999
  • This study was conducted to investigate the kinds of health promotion program which workers want, worker's intention for participation, proper method, time, duration and manager. A self-administered questionnaire method was used to collect data from 412 employees of 3 worksites in Chungpook and Kyungkee. This survey was carried out from Aug. 10 to Aug. 20, 1998. The results of this study are as follows: 1. In male, among health promotion programs, favorite ones were physical fitness(32.2%), periodic health check-up(24.6%), and stress management(18.0%). In female, among health promotion programs, favorite ones were periodic health check-up(26.0%), physical fitness(22.0%), and body weight control(19.5%). 2. The more young subjects are, the more they like physical fitness program, and the female like body weight control program regardless of BMI. Manufacturing worker preferred back pain prevention program to clerical worker did. In female, drinker preferred stress management program to non-drinker did. 3. The more old subjects are, the more they like back pain prevention program, and non-smoker preferred body weight control program to smoker did. 4. In health promotion program format which the subjects wanted, learning of self-examination techniques was 41.1%, worksite screening was 3l.0%, availability of pamphlets and audiovisual materials was 20.0%, presentation of worksite educational sessions was 7.9%, and the most wanted manager for the program was medical doctor and then nurse, physical trainer, psychological counselor. The favorite health promotion program duration was less than 30 minutes(49.6%), and the favorite time was before work(49.6%). 5. Among respondents, 48.5% was smokers, 81.8% was drinkers, 39.9% engaged in the regular exercise, 68.2% engaged in regular diet habit. In vaccination, 50.2%, if possible, wanted to be vaccinated and 37.6% never wanted to be vaccinated. 6. Ex-smoker, ex-drinker, the subjects in the regular exercise, and in the regular diet habit responded they were in good health. There was a significant difference between exercise and health status. Need and intention for participation of health promotion program were high in ex-smoker, ex-drinker, the subjects in the regular exercise, and in the regular diet habit. According to results for this study, if the favorite programs, exercise, periodic health check-up, stress management program, are operated at a proper time and with managers they want, this programs can really raise the participation of employees. And as employees want to learn self-examination techniques if worksite educational sessions are performed, health promotion program can effectively be operated.

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EDNN based prediction of strength and durability properties of HPC using fibres & copper slag

  • Gupta, Mohit;Raj, Ritu;Sahu, Anil Kumar
    • Advances in concrete construction
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    • v.14 no.3
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    • pp.185-194
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    • 2022
  • For producing cement and concrete, the construction field has been encouraged by the usage of industrial soil waste (or) secondary materials since it decreases the utilization of natural resources. Simultaneously, for ensuring the quality, the analyses of the strength along with durability properties of that sort of cement and concrete are required. The prediction of strength along with other properties of High-Performance Concrete (HPC) by optimization and machine learning algorithms are focused by already available research methods. However, an error and accuracy issue are possessed. Therefore, the Enhanced Deep Neural Network (EDNN) based strength along with durability prediction of HPC was utilized by this research method. Initially, the data is gathered in the proposed work. Then, the data's pre-processing is done by the elimination of missing data along with normalization. Next, from the pre-processed data, the features are extracted. Hence, the data input to the EDNN algorithm which predicts the strength along with durability properties of the specific mixing input designs. Using the Switched Multi-Objective Jellyfish Optimization (SMOJO) algorithm, the weight value is initialized in the EDNN. The Gaussian radial function is utilized as the activation function. The proposed EDNN's performance is examined with the already available algorithms in the experimental analysis. Based on the RMSE, MAE, MAPE, and R2 metrics, the performance of the proposed EDNN is compared to the existing DNN, CNN, ANN, and SVM methods. Further, according to the metrices, the proposed EDNN performs better. Moreover, the effectiveness of proposed EDNN is examined based on the accuracy, precision, recall, and F-Measure metrics. With the already-existing algorithms i.e., JO, GWO, PSO, and GA, the fitness for the proposed SMOJO algorithm is also examined. The proposed SMOJO algorithm achieves a higher fitness value than the already available algorithm.

Sleep Quality and Associated Factors Among Firefighters in Bangkok, Thailand: A Cross-sectional Study

  • Nunnapat Piyachaiseth;Pornchai Sithisarankul;Jate Ratanachina
    • Journal of Preventive Medicine and Public Health
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    • v.57 no.1
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    • pp.83-90
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    • 2024
  • Objectives: Professional firefighters face various health hazards and are required to maintain both physical and mental fitness to effectively mitigate crises and respond to emergencies. Moreover, the long working hours and shift work of this profession impact sleep quality. This study investigated the quality of sleep and its associated factors among firefighters in Bangkok, Thailand. Methods: This was a cross-sectional study of firefighters affiliated with the Bangkok Fire and Rescue Department, Bangkok Metropolitan Administration, Thailand between January 2023 and March 2023. A cluster random sampling technique was utilized to distribute 600 questionnaires to firefighters in 15 fire stations. The questionnaire addressed demographic, work-related, and environmental factors. Sleep quality was assessed using the Thai version of the Pittsburgh Sleep Quality Index (PSQI). Data analysis involved both descriptive and inferential statistics. Bivariate and multiple logistic regressions were performed. Results: The response rate was 78.7% (n=472), and 44.1% of the firefighters reported poor sleep quality (PSQI score >5). Sleep quality was statistically associated with conflicting family relationships (odds ratio [OR], 1.8; 95% confidence interval [CI], 1.1 to 2.9), additional part-time jobs (daytime, OR, 2.4; 95% CI, 1.3 to 4.4; or nighttime, OR, 4.3; 95% CI, 1.1 to 16.7), noisy sleeping areas (OR, 1.7; 95% CI, 1.1 to 2.8), and the availability of adequate bedding (OR, 3.0; 95% CI, 1.8 to 4.9). Conclusions: Poor sleep quality among firefighters was associated with various personal, work-related, and environmental factors. Organizations should promote policies that improve sleep quality through good sleep hygiene practices and facilities.