• Title/Summary/Keyword: First-onset

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Ramsay Hunt Syndrome -Case report on two cases- (Ramsay Hunt 증후군 -2예 보고-)

  • Lee, Sang-Gon;Yeo, Sang-Im;Goh, Joon-Seock;Min, Byung-Woo
    • The Korean Journal of Pain
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    • v.5 no.2
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    • pp.263-268
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    • 1992
  • Involvement of the facial nerve(herpes zoster oticus, Ramsay Hunt Syndrome) is a rather common clinical syndrome. It begins with unilateral ear pain, followed shortly by a peripheral facial palsy. Paresis or paralysis may affect the muscles of facial expression, which also close the eyelids. The levator palpebrae which is innervated by the 5th cranial nerve is spared, so the eye may remain open. The rash is usually confined to the tympanic membrane and the external auditory canal. It may spread to involve the outer surface of the lobe of the ear, anterior pillar or the fauces and mastoid. There also may be a loss of taste in the anterior two thirds of tongue. At time, the auditory nerve involvement produces tinnitus, deafness and vertigo. The 5th, 8th and 10th nerves and even the upper cervical spinal nerve can be involved presumedly on the base of spread of the infective process along anastomotic connections between the facial nerve. The facial paralysis is identical to that of Bells palsy. Frequently the recovery of facial nerve function is incomplete, leaving the patient with some residual facial weak ness. We experienced 2 cases of Ramsay Hunt Syndrome. The first patients, 55 year old male, visited our pain clinic on the day when his left facial nerve start to paralyze. We injected 6 ml of 0.25% bupivacaine into his left stellate ganglion 15 times. TENS was also applicated simultaneously. His facial paralysis was recovered completely 3 weeks after treatment without any complications. Another one, 53 year old male, visited us 7 weeks after onset of facial paralysis. He has been treated conventional oriental method(acupuncture, massage, warm application, etc). But the degree of his left facial paralysis didn't improve at all He has been treating with SGB 50 times and TENS for 2 months. Temporal and zygomatic branch of his left facial nerve recovered nearly completely but buccal and mandibular branch did not recover completely. We are willing to insist on the early treatment is the best choice in managing of Ramsay Hunt Syndrome.

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Burden of disease of major cancers assessment using years of lives with disability in Korea (장애에 따른 상실건강년수를 활용한 우리 나라 주요 암질환의 질병부담에 관한 연구)

  • Yoon, Seok-Jun;Chang, Hye-Jung;Shin, Young-Soo
    • Journal of Preventive Medicine and Public Health
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    • v.31 no.4 s.63
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    • pp.801-813
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    • 1998
  • This study was carried out for the burden of disease of major cancers assessment using years of lives with disability in Korea. With the years of lives with disability, this indicator was applied in order to estimate burden of major cancer disease. For this work, We also estimated incidence rate, remission rater case fatality rate, average age of onset, expected duration with disability in each cancer disease. As sources of information, national health insurance data and national mortality registration data were analyzed. The results of the study are as follows; The top five causes of the burden of major cancer disease are evaluated as stomach cancer, liver cancer, colon and rectum cancer, esophageal cancer, lung cancer in male. The top five causes of the burden of major cancer disease are evaluated as stomach cancer, esophageal cancer, liver cancer, uterine cervix cancer ovarian cancer in female. The process of evaluating the burden disease of major cancers in Korea has not finished with this paper. This study should be seen as the first in a series in Korea. It is necessary to analyse with more accuracy the assumptions behind the methodology.

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A Review of Static Blood Pattern in Stroke Pattern Diagnosis (한의 중풍 변증 표준화 연구에서 어혈증에 관한 고찰)

  • Lee, Jung-Sup;Kim, So-Yeon;Kang, Byoung-Kab;Ko, Mi-Mi;Kim, Jeong-Cheol;Oh, Dal-Seok;Kim, Yoon-Sik;Lee, In;Cho, Ki-Ho;Chen, Chan-Yong;Han, Chang-Ho;Bang, Ok-Sun
    • The Journal of Internal Korean Medicine
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    • v.30 no.4
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    • pp.813-820
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    • 2009
  • Background : Static blood is a kind of etiological factor including stagnated blood and blood overflowed out of the vessels. It is one of the causes of stroke in oriental medicine. Objectives : The purpose of this study was to evaluate the static blood pattern and its indicators in stroke pattern diagnosis. Methods : For the standardization of pattern diagnosis in stroke, we set 5 patterns (Fire-heat, Dampness-phlegm, Static blood, Qi deficiency, Yin deficiency) and developed 61 indicators. Patients with a first-ever stroke, within 1 month after the onset of stroke. Two physicians checked the indicators independently. They then performed pattern diagnosis and rechecked the indicators which were referred to pattern diagnosis. If pattern identifications were diagnosed the same, it would confirm pattern identification. We examined the frequency of all indicators and referred indicators in static blood pattern patients. Results : In 859 patients, static blood pattern was shared by 24(2.8%). The indicators which affect static blood pattern were mainly rough pulse and bluish purple tongue, other indicators were not major effectors. Conclusion : This result shows that it is inconsistent to set up static blood pattern as a major pattern in stroke. Nevertheless, static blood is still a valuable concept in the clinical field. Other study methods will be required to establish the pattern diagnostic indicators for static blood pattern.

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A Study of Patients Who Visited the Emergency Department at a Korean Medical Hospital: A Retrospective Chart Review (한의과대학 부속 한방병원 응급실 내원환자에 대한 고찰 : 후향적 차트리뷰)

  • Ryu, Hae-rang;Kim, Yoon-jung;Kim, Young-kyun;Kim, Kyoung-min
    • The Journal of Internal Korean Medicine
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    • v.39 no.3
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    • pp.350-362
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    • 2018
  • Objectives: By analyzing the characteristics and the distribution of diseases of patients who visited the emergency room of a Korean medical hospital, we sought to determine the methods of activating the Korean emergency medical system and to use this analysis as a basis for future research. Methods: We conducted a retrospective review of 959 patients who visited the emergency department of the Dong-Eui University Korean Medical Hospital from January 2016 to December 2016. The review was conducted using electronic medical records created during the emergency department visit. Results & Conclusions: In distribution of sex, the rate of males was 47.9%, and that of females was 52.1%. In distribution of age, the greatest number of patients were in their 50s (27.5%), followed by those in their 60s (19.9%) and 40s (14.8%). In distribution of residence, most patients were from Busan (84.9%). In distribution of week, more patients visited the emergency room on Sundays and holidays (44.3%). September was the busiest month (12.5%). Visits usually occurred during daytime and nighttime, and there were few visits at dawn. In the analysis of the time interval between onset of symptoms and the emergency room visit, most patients visited within 24 hours (46.5%). In the distribution of diseases, facial palsy was the most common (34.6%). In the systematic distribution of diseases, circulatory diseases were the most common (56.7%), followed by diseases of the musculoskeletal system (28.6%). The rate of first emergency room visit was 52.9%, and the rate of revisit was 47.1%. The rate of hospitalization after emergency room treatment was 27.5%, and the rate of discharge was 72.4%. The rate of revisit was 63.4%. In the distribution of treatment before arrival at the emergency room, direct was the most common (51.0%), and the outpatient department of western medicine was next. In the distribution of treatment in the emergency room, acupuncture was the highest (91.4%), followed by herb-med (43.0%).

Agro-climate Characteristics and Stability in Crop Production of Daegwallyeong Area in Korea (기상자료 분석을 통한 대관령 지역의 작물 최저 한계온도일 추정)

  • Ryu, Jong-Soo;Lee, Jeong-Tae;Lee, Gye-Jun;Oh, Dong-Shig
    • Korean Journal of Soil Science and Fertilizer
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    • v.45 no.6
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    • pp.1153-1156
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    • 2012
  • Daegwallyeong area to be formed along the mountainous terrain more above 800 m of sea level is known as the cold zone to occur frequently wind, rain and fog. This study to evaluate the stability of crop production and agricultural production potential in the Daegwallyeong was calculated for the low temperature frequency of occurrence and potential evapotranspiration changes with announce the release of Korea Meteorological Administration (KMA) from 1972 to 2009 up to 38 years. Evapotranspiration calculated FAO and other international standard method authorized under the PENMAN-MONTEITH Method was used, and the low temperature onset and frequency of the Gumbel probability density function was used. As a result, the variation of day evaporation for 38 years were showed to respectively width of variation from maximum $9mm\;day^{-1}$ to minimum $0.5mm\;day^{-1}$. The frequency of reappearance to first emergence day that lasts more than 5 days with temperature $5^{\circ}C$ over is 3 April a 50-year frequency, 10 April a 25-year frequency, 20 April a 10-year frequency, 28 April a 5-year frequency, 8 May a 2-year frequency. Psychrotrophic crop to growth temperature more than $5^{\circ}C$ can be secured to stable production with planting after May 8, prior to planting for normal growth can be seen that the risk of growth.

Acoustic differences according to the epileptic focus in benign partial epilepsy with centrotemporal spikes patients (양성 부분 간질 환아에서 간질 발생 위치에 따른 음성언어 분석)

  • Kim, Jung Tae;Choi, Sang Hoon;Kim, Sun Jun
    • Clinical and Experimental Pediatrics
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    • v.50 no.9
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    • pp.896-900
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    • 2007
  • Purpose : The aim of this study was to investigate the speech problems in benign rolandic epilepsy (BRE) according to the seizure focus in EEG and semiology. Methods : Twenty three patients [right origin (13 patients) or left side (10 patients)] who met the BRE criteria by International League Against Epilepsy (ILAE) were prospectively enrolled. We excluded the patients who had abnormal MRI or showed both side spikes in EEG. Computerized Speech Lab was used to assess the speech characteristics of the patients. Results : The error pattern of laryngeal articulation in BRE was exclusively substitution of stop consonants, these errors showed more frequent in the left group (16.0% vs 25.5%). Voice onset time (VOT) of stop consonants and Total duration (TD) of word in both groups were prolonged than normal control group, especially in left group (P<0.05). The first formant of vowel /o/ and second formant of /e/ were significantly decreased in left group (P<0.05). The right group scored wider on pitch range ($192.9{\pm}54.0Hz$) and energy range in spontaneous speech ($14.2{\pm}6.4db$) than the left group ($233.3{\pm}12.5Hz$, $19.4{\pm}9.3db$, respectively, P>0.05). Duration of counting (5 to 9) in left group slower than right group ($8.6{\pm}1.7$ vs $7.9{\pm}1.8sec$). Conclusion : Our data suggested that interictal spikes and seizures in either centrotemporal sides, especially left side group, may induce speech problems. We recommend the logopedic and phoniatric evaluations of speech in BRE patients.

The Lexical Access of Regular and Irregular Korean Verbs in the Mental Lexicon (한국어 규칙 동사와 불규칙 동사의 심성 어휘집 접근 과정)

  • Park, Hee-Jin;Koo, Min-Mo;Nam, Ki-Chun
    • Korean Journal of Cognitive Science
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    • v.23 no.1
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    • pp.1-23
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    • 2012
  • This study investigated the lexical access processing of inflected Korean verbs in the mental lexicon. In Korean, verbs can be classified into two main types of inflections, which are regular and irregular inflections, which can be further divided into three types of regular inflections and two types of irregular inflections. A masked priming lexical decision task was used and the priming effects were compared. Experiments were carried out using the five different types of verbal inflections in Korean: (1) No change-regularity (regular verbs with no orthographical or phonological changes), (2) Phonological change-regularity (regular verbs with phonological changes to the stem only), (3) Orthographical change-regularity (regular verbs that only undergo orthographical changes), (4) Stem change-irregularity (the stem is omitted or alternated with the other phoneme of the stem in irregular verbs), (5) Ending change-irregularity (irregular verbs with changes in the endings by phoneme substitution). The first three types are regarded as regular verbal inflections whereas the latter two types are regarded as irregular verbal inflections. The infinitive forms of the verb were presented as target words and three different conditions were presented as prime words. The three conditions included regular verbal inflection, irregular verbal inflection, and a control condition in which morphologically and semantically unrelated primes were presented. In addition, different stimulus onset asynchrony (SOA) were manipulated (43ms, 72ms, 230ms) to examine the time frame of the morphological decomposition process in word recognition. The results revealed that there were significant priming effects in all three SOAs across conditions. Hence, there was no significant differences in priming effects between regular and irregular verbal inflection conditions. This may suggest that Korean verb processing does not adopt different processing routes for regular and irregular inflections, which can also be an indication of earlier morphological information processing for Korean verbs.

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Age of Diagnosis of Breast Cancer in China: Almost 10 Years Earlier than in the United States and the European Union

  • Song, Qing-Kun;Li, Jing;Huang, Rong;Fan, Jin-Hu;Zheng, Rong-Shou;Zhang, Bao-Ning;Zhang, Bin;Tang, Zhong-Hua;Xie, Xiao-Ming;Yang, Hong-Jian;He, Jian-Jun;Li, Hui;Li, Jia-Yuan;Qiao, You-Lin;Chen, Wan-Qing
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.22
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    • pp.10021-10025
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    • 2014
  • Background: The study aimed to describe the age distribution of breast cancer diagnosis among Chinese females for comparison with the United States and the European Union, and provide evidence for the screening target population in China. Materials and Methods: Median age was estimated from hospital databases from 7 tertiary hospitals in China. Population-based data in China, United States and European Union was extracted from the National Central Cancer Registry, SEER program and GLOBOCAN 2008, respectively. Age-standardized distribution of breast cancer at diagnosis in the 3 areas was estimated based on the World Standard Population 2000. Results: The median age of breast cancer at diagnosis was around 50 in China, nearly 10 years earlier than United States and European Union. The diagnosis age in China did not vary between subgroups of calendar year, region and pathological characteristics. With adjustment for population structure, median age of breast cancer at diagnosis was 50~54 in China, but 55~59 in United States and European Union. Conclusions: The median diagnosis age of female breast cancer is much earlier in China than in the United States and the European Union pointing to racial differences in genetics and lifestyle. Screening programs should start at an earlier age for Chinese women and age disparities between Chinese and Western women warrant further studies.

Wavelet-based Pitch Detector for 2.4 kbps Harmonic-CELP Coder (2.4 kbps 하모닉-CELP 코더를 위한 웨이블렛 피치 검출기)

  • 방상운;이인성;권오주
    • The Journal of the Acoustical Society of Korea
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    • v.22 no.8
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    • pp.717-726
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    • 2003
  • This paper presents the methods that design the Wavelet-based pitch detector for 2,4 kbps Harmonic-CELP Coder, and that achieve the effective waveform interpolation by decision window shape of the transition region, Waveform interpolation coder operates by encoding one pitch-period-sized segment, a prototype segment, of speech for each frame, generate the smooth waveform interpolation between the prototype segments for voiced frame, But, harmonic synthesis of the prototype waveforms between previous frame and current frame occur not only waveform errors but also discontinuity at frame boundary on that case of pitch halving or doubling, In addtion, in transition region since waveform interpolation coder synthesizes the excitation waveform by using overlap-add with triangularity window, therefore, Harmonic-CELP fail to model the instantaneous increasing speech and synthesis waveform linearly increases, First of all, in order to detect the precise pitch period, we use the hybrid 1st pitch detector, and increse the precision by using 2nd ACF-pitch detector, Next, in order to modify excitation window, we detect the onset, offset of frame by GCI, As the result, pitch doubling is removed and pitch error rate is decreased 5.4% in comparison with ACF, and is decreased 2,66% in comparison with wavelet detector, MOS test improve 0.13 at transition region.

Efficacy of Antiepileptic Drug on the Benign Childhood Epilepsy with Centro-Temporal Spikes (중심-측두엽 극파를 보이는 양성 소아 간질 환자에서 항경련제 투여의 유효성)

  • Oh, Mee Hye;Kim, Soo Young;Seo, Won Hee;Pee, Dae Hun;Choi, Byung Min;Eun, Baik-Lin
    • Clinical and Experimental Pediatrics
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    • v.46 no.9
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    • pp.893-897
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    • 2003
  • Purpose : Benign childhood epilepsy with centrotemporal spikes(BECT) is characterized by an excellent prognosis. Therefore, the necessity for the use of antiepileptic drugs is controversial. The object of this study is to know about the long-term follow-up of BECT, comparing daily treatment with antiepileptic drug(AED) versus no medication. Methods : We retrospectively studied 56 cases of BECTs, examined at Pediatric Neurology Clinic, Korea University Medical Center as reference study time, August 2002. Thirty-eight patients didn't have mediation(group I), while eighteen patients received one or two AED(group II). We evaluated demographics, clinical manifestations at diagnosis, EEG findings and clinical courses in groups I & II. Results : There was no significant differences of sex, age, seizure frequency, seizure type, seizure onset time, family history and EEG findings between group I & II. The reasons to start AED were : parents' anxiety(three cases), frequent seizure(12 cases) and daytime seizure(three cases). There was no evolution of status epilepticus and no difficulty in school performance. Conclusion : AED treatment was of no advantage and long-term prognosis was good regardless of treatment strategy. So it is advisable not to choose AED as the first line of therapy, provided that the patient himself/herself or the family understands the benign nature of BECT.