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Acoustic differences according to the epileptic focus in benign partial epilepsy with centrotemporal spikes patients  

Kim, Jung Tae (Department of Pediatrics, Department of Clinical Speech Pathology/Research Institute of Speech Science Medical School, Chonbuk National University)
Choi, Sang Hoon (Department of Pediatrics, Department of Clinical Speech Pathology/Research Institute of Speech Science Medical School, Chonbuk National University)
Kim, Sun Jun (Department of Pediatrics, Department of Clinical Speech Pathology/Research Institute of Speech Science Medical School, Chonbuk National University)
Publication Information
Clinical and Experimental Pediatrics / v.50, no.9, 2007 , pp. 896-900 More about this Journal
Abstract
Purpose : The aim of this study was to investigate the speech problems in benign rolandic epilepsy (BRE) according to the seizure focus in EEG and semiology. Methods : Twenty three patients [right origin (13 patients) or left side (10 patients)] who met the BRE criteria by International League Against Epilepsy (ILAE) were prospectively enrolled. We excluded the patients who had abnormal MRI or showed both side spikes in EEG. Computerized Speech Lab was used to assess the speech characteristics of the patients. Results : The error pattern of laryngeal articulation in BRE was exclusively substitution of stop consonants, these errors showed more frequent in the left group (16.0% vs 25.5%). Voice onset time (VOT) of stop consonants and Total duration (TD) of word in both groups were prolonged than normal control group, especially in left group (P<0.05). The first formant of vowel /o/ and second formant of /e/ were significantly decreased in left group (P<0.05). The right group scored wider on pitch range ($192.9{\pm}54.0Hz$) and energy range in spontaneous speech ($14.2{\pm}6.4db$) than the left group ($233.3{\pm}12.5Hz$, $19.4{\pm}9.3db$, respectively, P>0.05). Duration of counting (5 to 9) in left group slower than right group ($8.6{\pm}1.7$ vs $7.9{\pm}1.8sec$). Conclusion : Our data suggested that interictal spikes and seizures in either centrotemporal sides, especially left side group, may induce speech problems. We recommend the logopedic and phoniatric evaluations of speech in BRE patients.
Keywords
Rolandic epilepsy; Speech; Language;
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1 Staden U, Isaacs E, Boyd SG, Brandl U, Neville BG. Language dysfunction in children with Rolandic epilepsy. Neuropediatrics 1998;29:242-8   DOI   ScienceOn
2 Saint-Martin AD, Seegmuller C, Carcangiu R, Kleitz C, Hirsch E, Marescaux C, et al. Cognitive consequences of Rolandic Epilepsy. Epileptic Disord 2001;3:SI 59-65
3 Park JI, Kim SJ, Kim HG. Acoustic effects of carbamazepine in benign rolandic epilepsy. Epilepsy Behav 2005;7:468-71   DOI   ScienceOn
4 Beaussart M. Benign epilepsy of children with rolandic (centrotemporal) paroxysmal foci. Epilepsia 1972;13:795-811   DOI   ScienceOn
5 Wolff M, Weiskopf N, Serra E, Preissl H, Birbaumer N, Kraegeloh-Mann I. Benign partial epilepsy in childhood: selective cognitive deficits are related to the location of focal spikes determined by combined EEG/MEG. Epilepsia 2005;46:1661-7   DOI   ScienceOn
6 Hommet C, Billard C, Motte J, Passage G, Perrier C, Patrice Gillet P, et al. Cognitive function in adolescents and young adults in complete remission from benign childhood epilepsy with centro-temporal spikes. Epileptic Disord 2001;3:207-16
7 Papavasiliou A, Mattheou D, Bazigou H, Kotsalis C, Paraskevoulakos E. Written language skills in children with benign childhood epilepsy with centrotemporal spikes. Epilepsy Behav 2005;6:50-8   DOI   ScienceOn
8 Lundberg S, Frylmark A, Eeg-Olofsson O. Children with rolandic epilepsy have abnormalities of oromotor and dichotic listening performance. Dev Med Child Neurol 2005;47:603-8   DOI
9 Traccis S, Monaco F, Sechi GP, Moglia A, Mutani R. Long-term therapy with carbamazepine: effects on nerve conduction velocity. Eur Neurol 1983;22:410-6   DOI
10 Scheffer IE. Autosomal dominant rolandic epilepsy with speech dyspraxia. Epileptic Disord 2000;2(Suppl 1):19-22
11 Croona C, Kihlgren M, Lundberg S, Eeg-Olofsson O, Eeg- Olofsson KE. Neuropsychological findings in children with benign childhood epilepsy with centrotemporal spikes. Dev Med Child Neurol 1999;41:813-8   DOI   ScienceOn
12 Loiseau P, Beaussart M. The seizures of benign childhood epilepsy with rolandic paroxysmal discharges. Epilepsia 1972;14:381-9   DOI   ScienceOn
13 Weglage J, Demsky A, Pietsch M, Kurlemann G. Neuropsychological, intellectual, and behavioral findings in patients with centrotemporal spikes with and without seizures. Dev Med Child Neurol 1997;39:646-51   DOI   ScienceOn
14 Berroya AG, McIntyre J, Webster R, Lah S, Sabaz M, Lawson J, et al. Speech and language deterioration in benign rolandic epilepsy. J Child Neurol 2004;19:53-8   DOI
15 Wyllie E. The treatment of epilepsy principles & practice. 3rd ed. Philadelphia: Lippincott williams & Wilkins 2001:475- 84
16 Gunduz E, Demirilek V, Korkmaz B. Benign rolandic epilepsy: neuropsychological findings. Seizure 1999;8:246-9   DOI   ScienceOn