• Title/Summary/Keyword: First Passage

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Growth Properties and Cholesterol Removal Ability of Electroporated Lactobacillus acidophilus BT 1088

  • Lye, H.S.;Khoo, B.Y.;Karim, A.A.;Rusul, G.;Liong, M.T.
    • Journal of Microbiology and Biotechnology
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    • v.22 no.7
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    • pp.981-989
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    • 2012
  • This study aimed to evaluate the effects of electroporation on the cell growth, cholesterol removal, and adherence abilities of L. acidophilus BT 1088 and their subsequent passages. The growth of electroporated parent cells increased (P<0.05) by 4.49-21.25% compared with that of the control. This may be attributed to the alteration of cellular membrane. However, growth of first, second, and third passages of treated cells was comparable with that of the control, which may be attributed to the resealing of transient pores on the cellular membrane. Electroporation also increased (P<0.05) assimilation of cholesterol by treated parent cells (>185.40%) and first passage (>21.72%) compared with that of the control. Meanwhile, incorporation of cholesterol into the cellular membrane was also increased (P<0.05) in the treated parent cells (>108.33%) and first passage (>26.67%), accompanied by increased ratio of cholesterol:phospholipids (C:P) in these passages. Such increased ratio was also supported by increased enrichment of cholesterol in the hydrophilic heads, hydrophobic tails, and the interface regions of the membrane phospholipids of both parent and first passage cells compared with that of the control. However, such traits were not inherited by the subsequent second and third passages. Parent cells also showed decreased intestinal adherence ability (P<0.05; decreased by 1.45%) compared with that of the control, without inheritance by subsequent passages of treated cells. Our data suggest that electoporation could be a potential physical treatment to enhance the cholesterol removal ability of lactobacilli that was inherited by the first passage of treated cells without affecting their intestinal adherence ability.

Average run length calculation of the EWMA control chart using the first passage time of the Markov process (Markov 과정의 최초통과시간을 이용한 지수가중 이동평균 관리도의 평균런길이의 계산)

  • Park, Changsoon
    • The Korean Journal of Applied Statistics
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    • v.30 no.1
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    • pp.1-12
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    • 2017
  • Many stochastic processes satisfy the Markov property exactly or at least approximately. An interested property in the Markov process is the first passage time. Since the sequential analysis by Wald, the approximation of the first passage time has been studied extensively. The Statistical computing technique due to the development of high-speed computers made it possible to calculate the values of the properties close to the true ones. This article introduces an exponentially weighted moving average (EWMA) control chart as an example of the Markov process, and studied how to calculate the average run length with problematic issues that should be cautioned for correct calculation. The results derived for approximation of the first passage time in this research can be applied to any of the Markov processes. Especially the approximation of the continuous time Markov process to the discrete time Markov chain is useful for the studies of the properties of the stochastic process and makes computational approaches easy.

Heat/Mass Transfer Characteristics in A Rotating Duct with $180^{\circ}$ Turn ($180^{\circ}$ 곡관부를 가지는 회전 덕트에서의 열/물질전달 특성)

  • Won, Chung-Ho;Lee, Sei-Young;Cho, Hyung-Hee
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.25 no.3
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    • pp.405-413
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    • 2001
  • The present study investigates convective heat/mass transfer and flow characteristics inside a rotating two-pass rectangular duct. A naphthalene sublimation technique is employed to determine the detailed local heat transfer coefficients using the heat and mass transfer analogy. The objective of this study is to determine the effects of turning geometry with rotation for 0.0$\leq$Ro$\leq$0.24. The results reveal that the sharp-turn corner has the larger pressure drop and lower heat transfer in the post-turn region than those of the round-turn corner. The strong secondary flow enhances heat transfer for the round-turn corner. Coriolis force induced by the rotation pushes the high momentum core flow toward the trailing wall in the first passage with radially outward flow and toward the leading wall in the second passage with radially inward flow. Consequently, the high heat transfer rates are generated on the trailing surface and the leading surface in the first and second passage, respectively. However, the strong secondary flow due to the turning dominates the flow pattern in the second passage, thus the heat transfer differences between the leading and trailing surfaces are small with the rotation.

Estimate of First-Passage Probability for Hazard Fluctuating Wind Velocity (재난 변동풍속의 최초파괴확률 평가)

  • Oh, Jong Seop;Heo, Seong Je
    • Journal of Korean Society of Disaster and Security
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    • v.6 no.2
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    • pp.23-30
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    • 2013
  • A dynamic analysis of random vibration processes is concerned with the first excursion probability based on first passage time during some specified lifetime or duration of the excitation. This study is concerned with the estimation of first-passage probability for hazard fluctuate wind velocity in the major cities reflecting the recent meteorological with largest data samples (yearly 2003-2012). The basic wind speeds were standardized homogeneously to the surface roughness category C, and to 10m above the ground surface. In this paper, the hazard fluctuate wind velocities are treated as a time-independent (stationary) random process and Gaussian random processes. The first excursion probability were calculated from Poisson model based on the independent event of level crossing & two-state Markov model based on the envelopes of level crossing.

The Effect of Combustion Chamber Shape on the Performance of Swirl Chamber in Diesel Engine(II) (와류실식 소형 디젤기관의 연소실 형상이 기관 성능에 미치는 영향(II))

  • Ra, Jin-Hong
    • Journal of Ocean Engineering and Technology
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    • v.13 no.3B
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    • pp.47-55
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    • 1999
  • A study on swirl chamber for diesel engine is to realize lower fuel consumption and exhaust emission than the current marketing engines. Author formerly reported the performance characteristics of small IDI diesel engine with swirl chamber by changing the jet passage area and its angle, and the depth and shape of the piston top cavity. Following after the first report, in this paper, the characteristics of fuel consumption, soot emission, and exhaust gas temperature were examined and analyzed after dimension of jet passage area expanded to $70.1mm^2$ The results were that the optimum values of the jet passage area depending on the depth of the piston top cavity were different at each engine speeds and loads, and in accordance with application of engine running conditions they were able to be selected as optimum dimensions of each design parameters.

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Improvements of the Public Pedestrian Passage in the Apartment Complex from Crime Prevention Through Environmental Design Aspect (범죄예방 환경설계 관점에서 공동주택 단지 내 공공보행통로의 개선방안 연구)

  • Lee, Seung-Ji
    • Journal of the Architectural Institute of Korea Planning & Design
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    • v.34 no.6
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    • pp.135-142
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    • 2018
  • A public pedestrian passage induces traffic into the apartment complex, and therefore, it requires the application of Crime Prevention Through Environmental Design(CPTED). This paper aims to analyze the conditions and to suggest the improvements of public pedestrian passages in apartment complexes, applying a 3-D approach from CPTED aspect. The first aspect is "Designation": 1)The linkage between the public pedestrian passages is weak, and their designated purpose becomes unclear. 2)When the designated purpose is not considered for each complex, the closure rate is high. 3)The closure rate of the "Through type" is high. It suggests that the pedestrian network should be built and vitalized at the local urban level. The second aspect is "Definition." The public pedestrian passage lacks a social, cultural, and legal definition and only has a passive physical definition. It suggests that a legal definition and specialized guildline be prepared. The third aspect is "Design": 1)Insufficient territoriality exists between the public pedestrian passage and the inside of the complex. Territoriality should be reinforced between the public pedestrian passage and the rest of the internal territory. 2)The landscaping adjacent to the public pedestrian passage lacks deliberation. Since this is where safety and privacy collide, detailed design and maintenance of the landscaping is required. 3)It lacks systematical crime prevention facilities and should compensate accordingly.

A Statistical Study of Foreign Bodies in Food and Air Passage (식도 및 기도이물의 통계적 고찰)

  • 손영규;양희찬;최정현;신명수;이선철
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1982.05a
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    • pp.6.2-7
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    • 1982
  • We have observed foreign bodies in food and air passage in 270 cases during the period from Sep. 1976 to Aug. 1981 in E.N.T. department of Han Gang Sacred Heart Hospital. The following results were obtained. 1) Distribution of location was 256 cases (94.8%) in food passage and 14 cases(5.2%) in air passage. 2) Age distribution was predominent in under 5 years old showing 198 cases(77.7%) in food passage and 10 cases (71.4%) in air passage. Under 5 years old group in the cases of food passage, coin was the most frequent material : 175 cases(87.9%), and in the cases of air passage, plastic material was the most frequent material : 5 cases(50.0%). Over 40 years old group in the cases of food passage, bony pieces was the most frequent material : 8 cases(47.1%), and meats was second frequent material: 6 cases. 3) Male seems to be more frequently involved than female in cases of food and air passage. Food passage - Male: Female - 151 : 105 (1.4:1) Air passage - Male : Female - 10:4 (2.5:1) 4) Coin was the most frequent foreign body in food Passage (199 cases-77.7%). Others were metals, bony pices, and meats. Plastic material was the most frequent foreign body in air passage (7 cases-50%). 5) In the locality of food passage, the first narrowing of the esophagus was the most frequent site, and air passage, the bronchus-especially right bronchus-was the most frequent site. 6) During of lodgement was 218 cases (85.2%) within 24 hours in food passage and 9 cases (64.3%) within 24 hours in air passage, and in air passage one case visited 5 months later after the accident.

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A Distribution for Regulated ${\mu}-Brownian$ Motion Process with Control Barrier at $x_{0}$

  • Park, Young-Sool
    • Journal of the Korean Data and Information Science Society
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    • v.7 no.1
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    • pp.69-78
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    • 1996
  • Consider a natural model for stochastic flow systems is Brownian motion, which is Brownian motion on the positive real line with constant drift and constant diffusion coefficient, modified by an impenetrable reflecting barrier at $x_{0}$. In this paper, we investigate the joint distribution functions and study on the distribution of the first-passage time. Also we find out the distribution of ${\mu}-RBMPx_{0}$.

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A Feasibility Study on the Flow Passage Shape for an Inline Francis Hydro Turbine

  • Chen, Chengcheng;Singh, Patrick Mark;Inagaki, Morihito;Choi, Young-Do
    • The KSFM Journal of Fluid Machinery
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    • v.18 no.2
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    • pp.5-13
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    • 2015
  • The aim of this study is to investigate the feasibility of a new type of casing for the inline Francis hydro turbine. Comparing with the traditional turbine with spiral casing, this turbine is unique for its flow passage shape at the first stage of flow to the turbine, very similar to a pipe, called inline casing. Before the commercialization of this new type of casing, a global investigation of the inline casing must be conducted. Preserving the structural characteristics of simple, compact-size and convenient for manufacture, different shapes of the belt passage, vertical corner and stay vanes are applied to investigate the influence of flow passage shape on the turbine performance. Stable and relatively high efficiency is achieved regardless of flow passage shape difference proving the feasibility of the inline casing used in a hydro turbine.

A Statistical Study of Foreign Body in Food and Air Passage (식도 및 기도이물의 통계적 고찰)

  • 조진규;안회영;신명수;박문서;한상욱
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1981.05a
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    • pp.3.3-4
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    • 1981
  • We have observed foreign body in food and air passage in 138 cases during the period from Jan. 1972 to Dec. 1980 in E.N.T. department of Kyung Hee university hospital. The following results were obtained. 1) Age distribution was predominent in under 5 years old showing 102 cases (73.9%). 2) Distribution of location was 132 cases in food passage and 6 cases in air passage. 3) In food passage, malewas 81 cases (61.4%). In air passage, male was 4 cases(66.7%). 4) Coin was the most frequent foreign body in food passage. Others were metals, meats, bony pieces, and shell. 5) Distribution of lodgement was frequent in first narrowing of esophagus. 6) Duration of lodgement was 112 cases (84.8%) within 24 hours in food passage and 4 cases (66.7%) within 24 hours in air passage.

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