• Archives of Reconstructive Microsurgery
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• 제8권2호
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• pp.139-148
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• 1999

Since Nakayama's first report about venous flap, many experimental and clinical studies were done about this new type of flap. And due to its various benefits, its applications as arterialized venous free flap type have increased recently. In this study we have attempted to reconstruct composite of defects of the hand with new modification of arterialized venous free flap and simultaneous reconstruction of skin, nerve, tendon were performed successfully. From 1994 to 1999, the defects of the hands in 35 patients were reconstructed with various modifications of arterialized venous free flaps. The range of age was from 19 to 55 years and size of flap ranged from $1{\times}2cm\;to\;14{\times}9cm$. Among them, 12 cases of flap over 20cm in size were included. Indications of flaps were as follows: resurfacing of the defects of the skin (9 cases), simultaneous reconstruction of extensor, skin and digital nerve(2 cases), reconstruction of the skin with extensor(5 cases), as a flap-through type vascular reconstruction(6 cases), for digital nerve reconstruction(2 cases), contracture release(3 cases), and finger tip reconstruction(9 cases). All of the cases except one survived with marginal skin necrosis less than 10%. And relatively large flaps over 20cm in size successfully survived without any delay procedures. Composite reconstructions including tendon and nerve were successful with new modifications of this flap. Arterialized venous free flap is one of the useful procedure in reconstruction of the hand because it has many advantages such as non-bulky and good quality of flap, variable length of pedicle, preservation of major vascular pedicle, less operation time, single operative field and in addition possibility of various modifications.

• 한국수정란이식학회지
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• 제31권1호
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• pp.61-64
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• 2016

We developed a polymerase chain reaction (PCR)-based molecular method for sexing and identification using sexual dimorphism between the Zinc Finger-X and -Y (ZFX-ZFY) gene and polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) for mitochondrial DNA (mtDNA) cytochrome B (CYTB) gene in meat pieces and commercial sausages from animals of different origins. Sexual dimorphism based on the presence or absence of SINE-like sequence between ZFX and ZFY genes showed distinguishable band patterns between male and female DNA samples and were easily detected by PCR analyses. Male DNA had two PCR products appearing as distinct two bands (ZFX and ZFY), and female DNA had a single band (ZFX). Molecular identification was carried out using PCR-RFLP of CYTB gene, and showed clear species classification results. The results yielded identical information on the sexes and the species of the meat samples collected from providers without any records. The analyses for DNA isolated from commercial sausage showed that pig was the major source but several sausages originated from chicken and Atlantic cod. Applying this PCR-based molecular method was useful and yielded clear sex information and identified the species of various tissue samples originating from livestock.

• 한국산학기술학회논문지
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• 제14권3호
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• pp.1245-1251
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• 2013

본 연구의 목적은 손잡이 유형에 따른 손가락 길이비(2D:4D)의 특성을 파악하는데 있다. 자료수집은 2010년 10월 4일부터 2012년 4월 30일까지 실시되었다. 연구대상자들은 손잡이 유형 평가 후, 캘리퍼를 사용하여 양손의 집게손가락과 반지손가락의 길이가 측정되었다. 연구 결과, 2D:4D는 왼손잡이는 왼손에서, 오른손잡이는 오른손에서 성차이가 두드러지게 나타났다. 그러나 손잡이 유형에 따라서는 남녀 모두 유의한 차이가 없었다. 남자에서 왼손잡이는 좌우 2D:4D 사이에 차이가 없었으나, 오른손잡이는 오른손이 유의하게 2D:4D가 낮은 것으로 나타났다. 좌우 2D:4D의 상관관계는 남자에서는 오른손잡이의 상관관계가 높았고, 여자에서는 왼손잡이의 상관관계가 높았다. 결론적으로, 2D:4D는 한국인에서 손잡이 유형사이에 차이는 없으나, 성차이와 좌우 2D:4D의 상관관계는 손잡이 유형에 따라 다른 특성을 나타낸다고 할 수 있을 것이다.

• Archives of Reconstructive Microsurgery
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• 제26권1호
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• pp.9-13
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• 2017

Purpose: Fingertip amputations are the most common type of upper limb amputations. Composite grafting is a simple and cost-effective technique. Although many factors have investigated the success of composite grafting, the success rate is not high. Therefore, this study was conducted to investigate whether the microscopic procedure process during composite grafts improves the success rate. Materials and Methods: Thirteen cases of unreplantable fingertip amputation underwent a microscopic resection procedure for composite graft in the operating room. The principle of the procedure was to remove the least devitalized tissue, maximize the clean tissue preservation and exact trimming of the acral vessel and to remove as many foreign bodies as possible. Results: All fingertips in the thirteen patients survived completely without additional procedures. Conclusion: Composite grafting allows for the preservation of length while avoiding the donor site morbidity of locoregional flaps. Most composite grafts are performed as quickly as possible in a gross environment. However, we take noticed the microscopic resection. This process is thought to increase the survival rate for the following reasons. First, the minimal resection will maximize the junction surface area and increase serum imbibition. Second, sophisticated trimming of injured distal vessels will increase the likelihood of inosculation. Third, accurate foreign body removal will reduce the probability of infection and make it possible to increase the concentration and efficiency in a microscopic environment. Although there is a need for more research into the mechanisms, we recommend using a composite graft under the microscopic environment.

• 한국컴퓨터정보학회논문지
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• 제19권11호
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• pp.63-72
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• 2014

본 논문에서는 깊이 카메라를 이용한 사용자의 손 모양 인식 시스템을 제안한다. 특히, 본 시스템에서 이용된 손 모양 템플릿은 수화 언어 중 한국어를 채택 하였다. 손 모양 인식 시스템은 손의 특징 검출과 특징들을 이용한 손 인식으로 크게 2 단계의 작업으로 나눌 수 있다. 손의 특징으로는 손가락의 개수, 길이, 손바닥의 넓이 등이 있다. 특징을 추출하기 위해 본 논문에서는 거리 변환(Distance Transform)을 이용한 손의 뼈대 검출 방법을 제안한다. 이 방법을 사용하면 기존의 윤곽선(Contour)을 이용한 손가락 검출보다 정확도 측면에서 향상된다. 손 모양 인식으로 손의 특징을 이용하여 각 분기를 잘 나눌 수 있는 결정 트리(Decision Tree)를 사용한다. 사용자의 입력을 이용하면 분기값이 정확하게 나오지 못하므로 이 분기 값을 결정하기 위해 해당 분기마다 SVM을 이용하여 분기값을 결정하였다. 실험결과에서는 기존의 연구 방법보다 제안된 방법이 특징 추출과 인식하는데 있어 더욱 개선되었음을 보인다.

• 대한물리의학회지
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• 제16권2호
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• pp.45-52
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• 2021

PURPOSE: This study examined the imaging procedure of pectoralis minor muscle thickness and assessed the intra- and inter-rater reliability of the muscle thickness measured by two raters using rehabilitative ultrasound imaging (RUSI) in healthy individuals. METHODS: Fifteen participants (aged 21 - 28, seven females, and eight males) were involved in the study. The primary rater palpated the coracoid process and the fourth rib, defined as the width of the index finger lateral to the sternum to avoid breast tissues, and lined the two landmarks. The second examiner checked 1 / 3 (1st point) and 1 / 2 (2nd point) of the line length as measurement points. The two raters obtained right side muscle images of the participants at a standardized sitting position using RUSI with a 7.5 MHz linear transducer at 40mm depth. For intra-rater reliability, the principal rater took three images per point and tried to take one more with an interval. For the inter-rater reliability, the other rater performed the same tasks as the principal rater on the same day. The reliability was analyzed using the intra-class correlation coefficient (ICC), the standard error of the measurement (SEM), and Bland and Altman plots. RESULTS: The reliability at all points was excellent for the same rater (ICC_3,1 = .973 - .978, SEM = .042 - .046), and between raters (ICC_2,1 = .939 - .959, SEM = .059 - .097). CONCLUSION: These findings show that the RUSI could be reliable for examining the pectoralis minor muscle thickness in healthy individuals at all measurement sites.

• 한국축산식품학회지
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• 제41권4호
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• pp.623-635
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• 2021

The effect of deer antler extract on muscle differentiation and muscle atrophy were evaluated to minimize muscle loss following aging. Various deer antler extracts (HWE, hot water extract of deer antler; FE, HWE of fermented deer antler; ET, enzyme-assisted extract of deer antler; UE, extract prepared by ultrasonication of deer antler) were evaluated for their effect on muscle differentiation and inhibition of 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR)-induced muscle atrophy in C2C12 cells. Morphological changes according to the effect of antler extracts on muscle differentiation were confirmed by Jenner-Giemsa staining. In addition, the expression levels of genes related to muscle differentiation and atrophy were confirmed through qRT-PCR. In the presence of antler extracts, the length and thickness of myotubes and myogenin differentiation 1 (MyoD1) and myogenic factor 5 (Myf5) gene expression were increased compared to those in the control group (CON). Gene expression of AMP-activated protein kinase (AMPK), MyoD1, and myogenin, along with the muscle atrophy factors muscle RING finger-1 (MuRF-1) and forkhead box O3a (FoxO3a) upon addition of deer antler extracts to muscle-atrophied C2C12 cells was determined by qRT-PCR after treatment with AICAR. The expression of MuRF-1 and FoxO3a decreased in the groups treated with antler extracts compared to that in the group treated with AICAR alone. In addition, gene expression of MyoD1 and myogenin in the muscle atrophy cell model was significantly increased compared that into the CON. Therefore, our findings indicate that antler extract can increase the expression of MyoD1, Myf5 and myogenin, inhibit muscle atrophy, and promote muscle differentiation.

• PNF and Movement
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• 제18권3호
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• pp.305-313
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• 2020

Purpose: The aim of this study was to investigate the relationship between a functional evaluation model and the Fugl-Meyer assessment (FMA) scale in evaluating the upper extremities of stroke patients Methods: Thirty-eight stroke patients were evaluated using the FMA and performed reaching and grasping motions using a three-dimensional motion analysis (Qquas 1 series, Qualisys AB, Sweden). The participants sat on a chair with a backrest. The position of the cup was located at a distance of 80% to the front arm length. The markers were attached to the sternum, acromion, elbow lateral epicondyle, ulnar styloid process, three metacarpal heads, and the distal phalanges of the thumb and index finger. The variables of the correlation between the functional evaluation model and the FMA scale were analyzed. Multiple regression (stepwise) was used to investigate the effect of the kinematic variables. Results: A significant negative correlation was found between the movement time (p < 0.05), movement unit (p < 0.05), and trunk displacement values (p < 0.05) in the FMA total scores, while a positive correlation was found between the peak velocity (p < 0.05) and maximum grip aperture values (p < 0.05). As a result of the multiple regression analysis, the most significant factor was the movement unit, followed by the general movement assessment and trunk displacement. The explained FMA total score value was 62%. Conclusion: This study presents a new functional evaluation model for assessing the reaching and grasping ability of stroke patients. The factors of the proposed functional evaluation model showed significant correlations with the FMA scale scores and confirmed that the new functional evaluation model explained the FMA by 67%. This suggests a new functional evaluation model for reaching and grasping stroke patients.

• 한국엔터테인먼트산업학회논문지
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• 제14권3호
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• pp.229-236
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• 2020

본 논문에서는 우리나라의 국악기중 대표적인 관악기인 대금의 음색을 분석하였다. 대금은 크게 정악대금과 산조대금으로 구분하여 사용되고 있는데, 정악대금은 궁중음악과 풍류음악에서 연주되고 있으며, 산조대금은 산조, 시나위, 민속음악에서 주로 연주된다. 이렇게 2개의 대금이 서로 다른 음악장르에서 연주되고 있는 이유는 악기의 개량에 따른 것인데, 관의 길이와 지공의 위치를 조정하여 산조대금이 정악대금에 비하여 빠른 연주가 가능하게 되었고, 다양한 연주기법을 적용할 수 있게 되었으며, 음색의 차이를 만들어 냄으로써 음악과 조화로운 악기의 선택을 가능하게 하였다. 이번 실험에서는 정악대금과 산조대금을 같은 음을 연주하여 녹음한 결과를 바탕으로 배음의 구조와 음색의 특징을 분석하였으며, 이를 통해 저음이 풍부한 정악대금이 궁중음악 등 장중한 분위기의 곡에 조화로우며, 상대적으로 고음이 맑은 산조대금이 독주 등 밝은 음악에 잘 어울린다는 것을 알 수 있었다.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2010년도 추계학술발표대회
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• pp.1422-1425
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• 2010

현대 사회에서 심장 질환은 3대 사망요인 중 하나로 매우 위험한 질환으로 분류되고 있으며 이에 의한 사망률이 매년 증가하는 추세이다. 기존의 의학적 상식에 의하면 스테로이드계의 남성 호르몬인 테스토스테론은 심장 질환과 관련이 있다고 되어 있다. 테스토스테론은 남성에게 중요한 호르몬으로 적당량이 분비되어야 건강하지만 너무 적게 분비가 되면 남성에게 있어 여러 가지의 병의 원인이 된다. 이와 같은 테스토스테론은 남성의 무명지의 길이에 영향을 주는데 분비량에 비례하여 무명지의 길이가 검지에 비해 길어진다. 따라서 본 논문에서는 심장 질환자와 정상인의 무명지 길이와 검지 길이를 비교, 분석하여 무명지의 길이와 심장 질환의 상관관계를 분석하였다.