• Journal of Biomedical Engineering Research
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• v.17 no.4
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• pp.499-506
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• 1996

Blood flow velocimeter is an essential device to measure the blood flow in skin tissue. In this study, we developed a high-speed LDV(laser Doppler Velocimeter) that has real time processing capability using a DSP(digital signal processing) chip and is able to continuously measure information about blood-flow based on a noninvasive method using self-mixing type laser diode. This LDV system has a simpler structure than any other typical blood flow velocimeter and is composed of new self-mixing probe, stabilizer circuits DSP board, and interf'ace boule We measured velocity of speaker-unit by operational frequencies to identify Doppler effect of this system, performed clinical experiment on bare finger tip and compared it with a commercial euipment BPM403A(USA).

• Journal of Biomedical Engineering Research
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• v.30 no.5
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• pp.401-411
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• 2009

In this paper, we correct pulse wave velocity(PWV) with heart-rate and derive regression equations to estimate intima-media thickness(IMT). Widely used methods for diagnosis of arteriosclerosis are IMT and PWV. Arterial wall stiffness determines the degree of energy absorbed by the elastic aorta and its recoil in diastole but there is not correlation between sclerosis and IMT in an existing study. In this study, we will correct PWV with heart-rate and get regression equation to estimate IMT using heart-rate correction index(HCI). We executed experiments for this study. Made up question of physical condition and measured electrocardiogram(ECG), photoplethysmogram (PPG) of finger-tip and toe-tip and ultrasound image of carotid artery. Calculated PWV and IMT using ECG, PPG and ultrasound image. We found that every p-value between PWV and IMT is not significant(<0.05). But p-value between IMT and HCI which is a corrected PWV using heart-rate is significant(>0.01). We use HCI and various measured parameter for estimating regression equation and apply backward estimation to select parameters for regression analysis. Result of backward estimation, found that only HCI is possible to derive proper regression equation of IMT. Relationship between PWV and IMT is the second order. Result of regression equation of E-H PWV is $R^2$=0.735, adj $R^2$=0.711. This is the best correlation value. We calculate error of its analysis for verification of earlobe PWV regression equation. Its result is RMSEP=0.0328, MAPE(%) = 4.7622. Like this regression analysis, we know that HCI is useful parameter and relationship between PWV, HCI and IMT. In addition, we are able to suggest possibility which is that we can get different parameter of prediction throughout just one measurement.

• Korean Journal of Applied Biomechanics
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• v.12 no.1
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• pp.173-191
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• 2002

The purpose of this study was defined efficient throw motion pattern to obtain the quantitative data and to achieve successful bowling through kinetic - kinematic variables on the throw motion. Subject of group composed of three groups : Higher bowlers who are two representative bowlers with 200 average points and one pro-bowler. Middle bowlers who are three common persons with 170 average points. Lower bowler who are three common persons with 150 average points. Motion analysis on throw motion in three groups respectively has been made through three-dimension cinematography using DLT method. Two high-speed video camera at operating 180 frame per secondary. One-way ANOVA has been used to define variable relations. Analyzed result and conclusion are the following : The displacement of back of the hand must have wider difference of each right-left displacement to increase the spin of the ball. In high bowlers group, difference between the front-rear position of back of the hand in case of success and that in case of failure in follow throw is 0.17m. That is to say, momentum in case of success come to increase greatly, compared with that in case of failure. To increase the spin of the ball, the potential difference should be narrower in follow through. In case of the high bowlers, the velocity of the front-rear direction of the back of the hand has been the fastest both in release and follow through, compared with those in other groups, which has contributed to increasing the spin force of the ball. The orders in the resultant velocity of the back of the hand has shown the this : the finger tip$\rightarrow$the back of the hand$\rightarrow$wrist.These orders made the proximal segment support the distal segment. The distal segment has provided the condition to accelerate the velocity. In case of failure, the suddenly increased velocity has caused the failure in the follow through. Acutely flexing the angle of the back of the hand has contributed to lifting to increase the spin of the ball.

• Archives of Plastic Surgery
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• v.35 no.3
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• pp.312-315
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• 2008

Purpose: Amelanotic melanoma represents a melanoma with an absence or a small number of melanin pigments and comprises 2% of all melanomas. These melanomas are frequently misdiagnosed, probably because of its nonspecific clinical features and difficulty in diagnosis, resulting in delayed diagnosis and treatment. We report a patient with amelanotic melanoma, who underwent surgical treatment with sentinel lymph node biopsy using gamma probe. Methods: A 32-year-old female was presented with a slowly growing ill-defined, hypopigmented nonerythematous lesion with nail defect on right index finger tip. Preoperative punch biopsy was performed, showing an amelanotic melanoma. Sentinel lymph node biopsy was done using gamma probe(Crystal probe system, CRYSTAL PHOTONICS GmbH, Germany) and confirmed no evidence of regional lymph node metastases. The patient underwent amputation at the proximal interphalangeal joint. Results: Histopathologic findings showed superficial spreading melanoma. There were no melanin pigments in Hematoxylin & Eosin stain but positive immunohistochemical stainings for S-100 protein and Hmb45, which were consistent with amelanotic melanoma. Patient's postoperative course was uneventful without any complication and had no evidence of recurrence of tumor in 6 months follow-up period. Conclusion: Amelanotic melanoma is extremely rare subtype of malignant melanoma with histopathologic findings of atypical melanocytes without melanin pigments. Early detection is crucial since survival is strongly related to tumor thickness and tissue invasion at the time of diagnosis. Wide excision is the treatment of choice and other conjunctive therapy has not been successful.

• Korean Journal of Oriental Medicine
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• v.16 no.3
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• pp.123-126
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• 2010

Objective : There are controversial opinions on the location of PC8 (Nogung). The one is to localize the point between the 2nd and 3rd metacarpal bone, the other is to localize the point between the 3rd and 4th metacarpal bone. The study was performed to provide an experimental evidence to standardize the location of PC8 point. Methods : We employed 30 healthy adults evenly in sex. To identify the location of PC8 in the hand, we took X-ray photograph in both hands of participants. Thin layer of leads were pasted on to PC7 and tip of middle finger prior to take X-ray photograph. The line connecting two points corresponding to the leads in X-ray film was read by a radiologist to decide that the line passes which side between the 2nd metacarpal space and the 3rd one. Results and Conclusions: The line passed the 3rd metacarpal space in 49 cases out of 60 hands (82 %). Data suggest that PC8 could be localized at the point between the 3rd and 4th metacarpal bone.

• Journal of Biomedical Engineering Research
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• v.31 no.6
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• pp.487-493
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• 2010

In this study, the circular friction massage technique was performed on the trapezius, the levator scapulae, and the deltoid muscles to collect the information on massage pressures and positions, and thus to utilize it in professional massage system design. Massage motion was measured with the 3-D motion capture system and finger pressures were simultaneously obtained with grip sensors. Massage motions, pressure patterns, and pressure times were different on each muscle, and the motion trajectory was similar to the ellipsoidal shape. The trapezius had higher pressure, longer massage time, and larger impulse than other muscles. These results could be useful to design a massage system based on biomechanical analysis. In order to improve massage effect, it is also strongly recommended that the tip of the system be similar with that of a human thumb in shape and material.

• The KIPS Transactions:PartB
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• v.16B no.5
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• pp.347-358
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• 2009

In this thesis, we develop a vision based hand motion recognition system using a camera with two rotational motors. Existing systems were implemented using a range camera or multiple cameras and have a limited working area. In contrast, we use an uncalibrated camera and get more wide working area by pan-tilt motion. Given an image sequence provided by the pan-tilt camera, color and pattern information are integrated into a tracking system in order to find the 2D position and direction of the hand. With these pose information, we estimate 3D motion plane on which the gesture motion trajectory from approximately forms. The 3D trajectory of the moving finger tip is projected into the motion plane, so that the resolving power of the linear gesture patterns is enhanced. We have tested the proposed approach in terms of the accuracy of trace angle and the dimension of the working volume.

• Journal of the Ergonomics Society of Korea
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• v.29 no.2
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• pp.203-210
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• 2010

For the development of a better product which fits to the target user population, physical workloads such as reach and visibility are evaluated using digital human simulation in the early stage of product development; however, ergonomic workload assessment mainly relies on visual observation of reach envelopes and view cones generated in a 3D graphic environment. The present study developed a quantitative assessment method of physical workload in a digital environment and applied to the evaluation of a Korean utility helicopter (KUH) cockpit design. The proposed assessment method quantified physical workloads for the target user population by applying a 3-step process and identified design features requiring improvement based on the quantified workload evaluation. The scores of physical workloads were quantified in terms of posture, reach, visibility, and clearance, and 5-point scales were defined for the evaluation measures by referring to existing studies. The postures of digital humanoids for a given task were estimated to have the minimal score of postural workload by finding all feasible postures that satisfy task constraints such as a contact between the tip of the index finger and a target point. The proposed assessment method was applied to evaluate the KUH cockpit design in the preliminary design stage and identified design features requiring improvement. The proposed assessment method can be utilized to ergonomic evaluation of product designs using digital human simulation.

• Journal of the Korean Society of Physical Medicine
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• v.7 no.4
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• pp.481-491
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• 2012

PURPOSE: This study find out the effect of improved two point discrimination (TPD), hand function and activities of daily living (ADL) performance through tactile stimulus of upper limb (U/L) in impaired characteristics of stroke METHODS: We selected 26 stroke patients in BMH who has problems with neglect, sensory and motor deficits. Patients were divided into 3 group with neglect group (NG), sensorimotor deficits group (SMG) and motor deficit group (MG). To compare each group we used assessment tools such as two point discrimination on affected side (TPDas) and unaffected side (TPDus), Manual functional test on affected side (MFTas) and unaffected side (MFTus) and Korean version modified barthel index (K-MBI). RESULTS: 1) In the NG, tactile stimulus on U/L was statistically important for TPDas (forearm, index finger tip) also SMG and MDG was statistically important for TPDas. 2) In the NG, SMG, there was statistically important for MFTas, MFTus and in the MG. K-MBI also was statistically importance. Among three group, there was an statistically important difference for TPTus (forearm, thenar, hypothenar), MFTas and MFTus. We analyzed the relationship among TPD, MFT and K-MBI and There was negative relationship between TPD, MFT and There was positive relationship between TPD and K-MBI CONCLUSION: In impaired characteristics of stroke patients, tactile stimulus on U/L influenced on two point discrimination, hand function and ADL's. And we also found relationship among somatosensory, hand function, and ADL performance.

• Clinical and Experimental Pediatrics
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• v.51 no.8
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• pp.886-891
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• 2008

Mixed connective tissue disease (MCTD) is characterized by diverse symptoms including rheumatoid arthritis, scleroderma, systemic lupus erythematosus, and dermatomyositis, associated with high titers of antibodies to extractable nuclear antigen (ENA), especially anti-ribonucleoprotein (anti-RNP) antibody. Since the first report of 25 cases with MCTD in adults, there have been only a few cases of MCTD reported in children. Here, we report a rare childhood case of MCTD in a 7-year-old girl presenting initially with Raynaud's phenomenon, swollen hands, and ulceration of the right index finger tip followed by alopecia and arthritis during follow-up.