• Title/Summary/Keyword: Fine-needle aspiration

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Primary Lung Tumors in Five Dogs (개의 원발성 폐 종양 5증례)

  • Kim You-seok;Bhang Dong-ha;Kim Min-kyu;Seo Kyoung-won;Joo Min-suk;Park Jung-hyun;Choi Ul-soo;Jung Joo-hyun;Choi Eun-wha;Yoon Junghee;Youn Hwa-young;Choi Min-cheol;Lee Chang-woo
    • Journal of Veterinary Clinics
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    • v.22 no.3
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    • pp.288-295
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    • 2005
  • Five dogs at the age of 2-13 years, with variant respiratory signs like as dry cough, dyspnea, exercise intorelance and lameness were presented. On thoracic radiographs, all dogs had abnormalities such as soft tissue density, round mass image, increased pulmonary infiltration and pleural effusion. All dogs were diagnosed as adenocarcinoma on cytopathologic examinations by fine needle aspiration with ultrasound guidance. Computed tomography was performed in three cases to evaluate clinical stage. Primary papillary adenocarcinoma was confirmed after necropsy in one case.

Imaging Diagnosis: Heartbase Tumor in a Dog (개의 심기저부 종양의 영상진단학적 특징)

  • Chang, Jin-Hwa;Jung, Joo-Hyun;Yoon, Jung-Hee;Choi, Min-Cheol
    • Journal of Veterinary Clinics
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    • v.25 no.1
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    • pp.48-51
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    • 2008
  • A ten-year-old Yorkshire Terrier developed serious abdominal distension and respiratory distress. Radiography and ultrasonography revealed a hyperechoic mass around the aorta that was contiguous with the right atrium and main pulmonary artery. It was resulted in failure of the right side of the heart including tricuspid regurgitation, hepatomegaly with dilation of the hepatic vein and severe ascites due to a large, expansile mass. Computed tomography(CT) identified a large mass originating at the cardiac hilar region and spanning from the cranial vena cava to the caudal vena cava. The tumor had invaded the cranial vena cava, caudal vena cava, heart and pleural wall. A tentative diagnosis of chemodectoma was assigned to the tumor through a fine needle aspiration. This report focuses on the typical features of imaging diagnosis of heartbase tumors by radiography, ultrasonography and CT.

Atypical Cushing's Syndrome Associated with Sex Steroids Excess in a Dog (개에서 발생한 성호르몬 과다 분비와 관련된 비정형 부신피질기능 항진증)

  • Kim, Jun-Hwan;Hong, Yeon-Jung;Lee, Hyeon-Seok;Park, Jin-Ho;Park, Chul
    • Journal of Veterinary Clinics
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    • v.29 no.5
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    • pp.400-403
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    • 2012
  • A 10-year-old, intact male, toy poodle was presented with abdominal distension, truncal alopecia, hepatomegaly, and sustained elevation of alkaline phosphatase. Vacuolar hepatopathy and glycogen deposition in hepatocytes were confirmed by liver biopsy and ultrasound-guided fine-needle aspiration with periodic acid-Schiff (PAS) staining of mass lesion respectively. Cortisol and some sex hormones associated with adrenal gland were analyzed at IDEXX Reference Laboratories before and 1 hour after ACTH stimulation. The results of analysis confirmed elevation of some sex hormones including androstenedione, progesterone and 17 hydroxyprogesterone, not cortisol concentration, before and 1 hour after ACTH stimulation. The dog was diagnosed as atypical form of hyperadrenocorticism associated with sex steroids excess. The treatment was initiated with trilostane (0.5 mg/kg, PO, q12hr) that is an adrenal steroid synthesis inhibitor. Trilostane was administered for 8 weeks and the clinical sign including truncal alopecia was improved.

A Case of Mesenteric Myxosarcoma in a Dog (개에서 발생한 장간막 점액육종의 한 증례)

  • Kim, Sang-Chan;Kim, Hyun-Wook;Choi, Ji-Hye;Jang, Jae-Young;Choi, Ul-Soo
    • Journal of Veterinary Clinics
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    • v.29 no.2
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    • pp.173-176
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    • 2012
  • A 6-year-old male Shih tzu dog was presented for evaluation of abdominal distention. Abdominal radiography and ultrasonography revealed a soft tissue density mass containing large amount of fluid. Ultrasonography-guided fine needle aspiration of the mass was performed and cytologic impression was granulation tissue with hematoma and fibroplasias. On exploratory laparotomy a mass was identified at the root of mesentery adhered to distal jejunum. Because the mass could not be separated from the attached jejuna loops, the mass and the adhered sites were surgically removed all together and enteroanastamosis was performed. Histologically a low grade myxosarcoma was diagnosed. Tumor cells were positive with alcian blue stain and Ki67 index by immunohistochemistry was 2.5. The dog recovered from surgery uneventfully, and has been in good condition without any signs of recurrence or metastasis for about 30 months after surgery.

A Case of Canine Uterine Adenocarcinoma with Negative Estrogen and Progesterone Receptor Expression (개의 에스트로겐과 프로케스테론 수용체 발현이 되지 않은 자궁 선암종 증례)

  • Cho, Hyang-Mi;Kim, Hyun-Wook;Kim, Hye-Jin;Choi, Ji-Hye;Jang, Jae-Young;Choi, Ul-Soo
    • Journal of Veterinary Clinics
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    • v.28 no.3
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    • pp.303-306
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    • 2011
  • A 12-year-old female mixed breed dog receiving a progesterone drug was referred for evaluation of an abdominal mass. Abdominal radiography and ultrasonography revealed a swollen uterus and an associated mass. Serum chemistry revealed hyperglobulinemia consistent with acute inflammation based on the results of serum protein electrophoresis. Fine needle aspiration of the mass guided by ultrasonography was performed for cytological evaluation. The cytological impression was consistent with adenocarcinoma. Exploratory laparotomy identified a uterine body mass, which was surgically removed for histopathology. Histology of the mass identified a uterine adenocarcinoma. Immunochemistry using anti-estrogen and progesterone receptor antibodies was performed and neoplastic cells were negative to both antibodies while some normal elements were reactive to both of them. Computer tomography demonstrated evidence of metastatic disease in the lung one week after the surgery and the dog died about 40 days after surgery.

Application of Low-Budget Protocol with Lomustine and Prednisolone for Multicentric Lymphoma in a Dog (개 다발성 림프종에 대한 Lomustine 및 Prednisolone을 이용한 Low-budget protocol 적용 증례)

  • Lee, Do-Hyung;Lim, Soo-Jung;Son, Sun-Ho;Lee, Sun-Hee;Jun, Hyung-Kyou;Choi, Ho-Jung;Lee, Young-Won;Cho, Sung-Whan;Song, Kun-Ho
    • Journal of Veterinary Clinics
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    • v.26 no.3
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    • pp.263-267
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    • 2009
  • A 9-year-old, female, Maltese Dog(2.15 kg of body weight) was referred to the Veterinary Medical Teaching Hospital, Chungnam National University with cervical masses, abdominal masses and petechia. Physical examination showed masses in mandibular, prescapular, inguinal, popliteal lymph node and abdominal subcutaneous hemorrhage. This case was diagnosed as the multicentric lymphoma by physical examination, laboratory examination, radiography, ultrasonography, CT, fine needle aspiration and histopathologic examination. This dog was treated by low-budget protocol with lomustine and prednisolone. The dog show that response duration and survival time is 143days and 263 days, respectively.

A case report of diagnosis and treatment of metastatic calcinosis circumscripta secondary to chronic renal failure (만성 신부전에서 속발한 metastatic calcinosis circumscripta의 진단과 치료 1례)

  • Park, Seong-Jun;Park, Hye-Yeon;Jeon, So-Bun;Choi, Ho-Jung;Jeong, Seong-Mok;Song, Kun-Ho;Cho, Jong-Ki;Lee, Young-Won;Shin, Sang-Tae;Kim, Myung-Cheol;Kim, Duck-Hwan
    • Korean Journal of Veterinary Research
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    • v.45 no.3
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    • pp.445-450
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    • 2005
  • A 1.35 kg, three-year-old, female, Yorkshire terrier was referred to the veterinary medical teaching hospital of Chungnam National University with an alopecia, scale, polydipsia and polyuria. During hospitalization, the patient revealed swelling and pain of all four foot pads. The hematology indicated nonregenerative anemia. Blood serum chemistry revealed elevation of BUN, serum creatinine and phosphorus contents. Radiographs of feet revealed increased radiodensity in the soft tissue of the foot pad. In ultrasonographs of abdomen, kidneys showed diffusely echodense renal cortex with loss of the normal corticomedullary boundary. Fine needle aspiration of the swollen pad cysts contained a amorphous basophillic chalky, white and pasty material. The culture result was negative for bacteria. In conclusion, it was diagnosed as metastatic calcinosis circumscripta secondary to chronic renal failure. An oral charcoal absorbent and aluminum hydroxide were used to treat this condition. After six weeks treatment, hyperphosphatemia was corrected and metastatic calcinosis circumscriptawas not presented any more.

Comparison of polymerase chain reaction for antigen receptor gene rearrangement and flow cytometric analysis for the diagnosis of canine lymphoma

  • Song, Ru-Hui;Yu, Do-Hyeon;Kim, Jun-Hwan;Lee, Hyun-Seok;Lee, Da-Mi;Park, Chul;Yu, Il-Jung;Park, Jin-Ho
    • Korean Journal of Veterinary Service
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    • v.34 no.3
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    • pp.265-271
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    • 2011
  • Lymphoma is the most common hematopoietic malignancy in dogs. Diagnosis of lymphoma is classically performed by morphological assessment and immunohistochemistry. But some cases in the early stage are difficult to distinguish and need more objective and accurate methods. So, Polymerase chain reaction (PCR) for antigen receptor rearrangements (PARR) and flow cytometric immunophenotype of lymphoma have been developed continuously. In this study, we performed these two methods to classify lymphoma type in 3 cases. According to PARR analysis, B cell origin lymphoma was diagnosed in two of three cases by testing PBMC and lymph node. All fine needle aspiration (FNA) samples of lymph nodes had high expression of CD21 on >88% of total cell population and PBMC samples also showed high expression of CD21 on >30% of total lymphocytes in those two cases, while the expression of CD3, CD4 and CD8 was absent. These results suggest that concurrent use of PARR and flow cytometric immunophenotype is more effective and valuable tool for the diagnosis and monitoring of canine lymphoma patients.

Diagnostic Application of Temporomandibular Joint Disorder and Ultra Sound Guided Oral &Maxillofacial application (초음파를 이용한 턱관절질환의 진단과 초음파 가이드의 활용)

  • Seong, Tae-Hwan;Park, Jung-Hyun;Kim, Sun-Jong
    • The Journal of the Korean dental association
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    • v.55 no.11
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    • pp.789-799
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    • 2017
  • Ultrasound images are noninvasive, can be observed in real time, have no radiation exposure, do not cause pain, and are not restricted in use depending on the patient's prosthetic implant or medical condition. Since the use of ultrasound in the dental field was first applied for tooth preparation in 1957, the use of diagnostic ultrasound for the first time in 1963 has been reported. Currently, it is used in the diagnosis of soft tissue lesions such as malignant tumor or salivary gland disease, fine needle aspiration test, temporomandibular joint disease, lymph node metastasis, measurement of muscle thickness and inflammatory diseases, differentiation of periapical cyst and granulation tissue, measurement of periodontal tissue thickness. The ultrasound image can be visualized in real time. The clinician can explain the structure to the patient while consulting the patient and consult the patient. When injecting the drug into a specific site or aspirating a specific site or substance, So that it can be confirmed and practiced. Recently, ultrasonic equipment specialized in the dental field has been developed and marketed, and it is expected that the use of ultrasonic waves will become active in the dentistry. In the future, development of popular equipment with size and frequency suitable for dental diagnosis and various researches on maxillofacial ultrasonic anatomy. If clinical studies are continuously carried out to demonstrate efficacy, ultrasound is expected to aid in accurate diagnosis and treatment throughout the dentistry.

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A Case of Inflammatory Pseudotumor Completely Resolved by Steroid Therapy (스테로이드 요법으로 완치된 염증성 가종양 1예)

  • Bang, Seung-Ho;Kim, Chi-Hong;Kwon, Soon-Seog;Kim, Young-Kyoon;Kim, Kwan-Hyoung;Moon, Hwa-Sik;Song, Jeong-Sup;Park, Sung-Hak
    • Tuberculosis and Respiratory Diseases
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    • v.40 no.6
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    • pp.709-713
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    • 1993
  • Inflammatory pseudotumor, also known as plasma cell granuloma, is a rare, benign tumor that affects at all ages and frequently involves the lung, gastrointestinal tract, and salivary gland. They are the most common, isolated, primary lesion of the lung in children less than 16 years of age, and usually present as circumscribed, peripheral, parenchymal tumors, which may be static or increase slowly in size without causing symptoms. Surgical excision is the treatment of choice bacause of the location and benign nature of this lesion. The prognosis after resection is excellent. Adjuvant therapeutic modalities include radiation and steroid therapy. Recently, we experienced a case of inflammatory pseudotumor of the lung, the diagnosis of which was made by percutaneous fine needle aspiration cytology examination. We tried steroid and the lesions of the lung was completely resolved. We report this case with a review of literatures.

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