Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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A Case of Mesenteric Myxosarcoma in a Dog

개에서 발생한 장간막 점액육종의 한 증례

  • Accepted : 2011.06.08
  • Published : 2012.04.30
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Abstract

A 6-year-old male Shih tzu dog was presented for evaluation of abdominal distention. Abdominal radiography and ultrasonography revealed a soft tissue density mass containing large amount of fluid. Ultrasonography-guided fine needle aspiration of the mass was performed and cytologic impression was granulation tissue with hematoma and fibroplasias. On exploratory laparotomy a mass was identified at the root of mesentery adhered to distal jejunum. Because the mass could not be separated from the attached jejuna loops, the mass and the adhered sites were surgically removed all together and enteroanastamosis was performed. Histologically a low grade myxosarcoma was diagnosed. Tumor cells were positive with alcian blue stain and Ki67 index by immunohistochemistry was 2.5. The dog recovered from surgery uneventfully, and has been in good condition without any signs of recurrence or metastasis for about 30 months after surgery.

6 년령의 수컷 시츄 견이 복부 팽만을 주 호소로 내원하였다. 복부 방사선 검사와 초음파 검사에서 많은 양의 액체를 포함하고 있는 연부조직 밀도의 종괴가 발견되었다. 종괴의 세포학적 검사를 위해 초음파 유도 세침흡인을 실시하였으며, 세포학적 검사 결과 섬유화가 동반된 육아조직이 의심되었다. 종괴의 확인과 수술적 제거를 위해 진단적 개복술을 실시하였다. 개복시 원위 공장부위에 인접한 장간막의 뿌리에서 유래한 종괴가 확인되었고 종괴는 원위공장 부위에 부착되어 있었다. 종괴와 부착 부위의 분리가 어려웠기 때문에 종괴와 부착 부위를 모두 수술적으로 제거하였으며 장문합술을 실시하였다. 종괴의 조직병리학적 검사 결과 저 악성도 점액육종이 진단되었으며, 종양 세포는 알시안 블루 염색에 양성 반응을 보였다. 추가로 실시한 Ki67 항체를 이용한 면역조직화학 염색 결과 Ki-67 지수는 2.5 였다. 환축은 절제술 실시 후 현재까지 30개월 동안 전이와 재발의 증거 없이 살고 있다.

Keywords

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